Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
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| Number | Title | Issue Date |
| 8076518 | Chain extenders This invention provides chain extender compositions. These compositions comprise (i) an aliphatic secondary diamine, and (ii) a component selected from the group consisting of: (a) a cy... | 12/13/2011 |
| 7875750 | Method of obtaining 2-amino-6-alkyl-amino-4,5,6,7-tetrahydrobenzothiazoles The present invention relates to a process for preparing 2-amino-6-alkyl-amino-4,5,6,7-tetrahydrobenzothiazoles (I) wherein the asterisk (*) represents an asymmetric carbon and R1 is C1-C6 alkyl; their enantiomers or mixtures thereof... | 01/25/2011 |
| 7485755 | Acid addition salt of carbasugar amine derivative An acid addition salt of a carba-sugar amine derivative represented by the following formula (1): wherein R1 and R2 each independently represents a hydrogen atom, or an alkyl group, an alkenyl group, a... | 02/03/2009 |
| 7432399 | Diols formed by ring-opening of epoxies A polyol monomer comprising the formula: R1 and R3 are —H, aliphatic, aromatic, or ether; R2 is aliphatic, aromatic, ester, ether, or acrylic, and R1 contains a hydroxyl group, ... | 10/07/2008 |
| 7419981 | Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor The instant invention relates to a combination of an alpha-2-delta ligand and a PDEV inhibitor for use in therapy, particularly in the treatment of pain, particularly neuropathic pain. Particularly preferred alpha-2-delta ligands are gabapentin and pregabalin. A par... | 09/02/2008 |
| 7365192 | Preparation method of valienamine from acarbose and/or acarbose derivatives using trifluoroacetic acid The present invention provides a preparation method of valienamine from acarbose or acarbose derivatives using organic acid TFA (trifluoroacetic acid). By using the method of the present invention, valienamine, the core precursor of voglibose which is a strong retar... | 04/29/2008 |
| 7276631 | Cyclopentylamine and cyclohexylamine derivatives as NK-1/SSRI antagonists The present disclosure relates to chemical compounds and their use in human therapy. A specific embodiment of the disclosure relates to compounds of Formula (I); or an isomer, a pharmaceutically acceptable salt or solvate thereof or a pharmaceutically acceptable for... | 10/02/2007 |
| 7232847 | 4-hydroxymethyl-1-aryl-cyclohexylamine compounds The invention relates to 4-hydroxymethyl-1-aryl-cyclohexylamine compounds, methods for their production, pharmaceutical formulations containing such compounds and the use of 4-hydroxymethyl-1-aryl-cyclohexylamine derivatives for producing medicines which are useful,... | 06/19/2007 |
| 7196226 | Fluoraminoolefins and fluorination reagents which can be prepared therefrom The present invention relates to fluorination reagents comprising 1-fluoro-1-aminoolefins and also processes for preparing fluorination reagents comprising 1-fluoro-1-aminoolefins. ... | 03/27/2007 |
| 7084303 | Tertiary amine compounds having an ester structure and processes for preparing same The present invention provides ester group-containing tertiary amine compounds of the formula (R1OCH2CH2)nN(CH2CH2CO2R2)3-n which, when used as additives in chemical a... | 08/01/2006 |
| 7038087 | Process for the production of optically active amino alcohols An object of the present invention is to provide a process for the production of an optically active amino alcohol, particularly an optically active amino alcohol of a trans-form, being excellent in economy and efficiency, and suitable for industry using easily avai... | 05/02/2006 |
| 7026514 | Compounds used to treat alcoholism N,N′-bis(3-aminopropyl)cyclohexane-1,4-diamine, of formula (I), is a new compound that is prepared by hydrogenation with Raney nickel catalyst of N,N′-bis(2-cyanoethyl)-cyclohexane-1,4-diamine, the latter being prepared by reaction between 1,4-cyclohexanediamine... | 04/11/2006 |
| 6962964 | Hydrogenation of methylenedianiline homologs and epoxy resins cured with same This invention relates to improved polyepoxide resins cured with a mixture of methylene bridged poly(cycloaliphatic-aromatic)amines and a process for preparing such polyepoxide resins as well as to the methylene bridged poly(cycloaliphatic-aromatic)amine composition... | 11/08/2005 |
| 6951958 | Solid phase parallel synthesis of tertiary amines Described is method for preparing tertiary amines comprising sequential, exhaustive alkylation of a hydroxylamine derivative and cleavage of the O—N bond using the following steps: a) reacting the hydroxylamine derivative with an alkylating agent or w... | 10/04/2005 |
| 6828462 | Unsaturated 1-amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists Unsaturated 1-Amino-alkylcyclohexane compounds which are systemically-active as NMDA, 5HT3, and nicotinic receptor antagonists, pharmaceutical compositions comprising the same, method of preparation thereof, and method of treating CNS disorders which invo... | 12/07/2004 |
| 6765104 | Transition metal complexes of n, n',n″trialkyl-cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use The present invention provides transition metal complexes of N,N′,N″-trialkyl-cis,cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use in vitro and in vivo, such as a therapeutic agent or a delivery/imaging agent. ... | 07/20/2004 |
| 6747149 | Glucamine salts for treating hepatitis virus infections N-Substituted glucamine compounds of formula I are effective in treatment of hepatitis infections, including hepatitis B and hepatitis C. In treating hepatitis infections the compounds of formular I may be used alone, or in combinatioin with another antiviral agent ... | 06/08/2004 |
| 6723879 | Process for preparing amino compounds by using salen-manganese complexes as the catalyst Disclosed is a process for the enantioselective production of an optically active amino compound by the amination of the C—H bond of an organic compound. The amino compound is produced by converting the C—H bond at the allyl position of an alkene or the C—H bo... | 04/20/2004 |
| 6632635 | Methods of refolding proteins Methods are disclosed for refolding proteins of the TGF-ଲ family of proteins. The methods employ as refolding agents one or more compounds which are acid substituted aminocyclohexanes.... | 10/14/2003 |
| 6583246 | Modifiers for anionic polymerization The invention provides modifiers for the anionic polymerization of conjugated dienes or of conjugated dienes with vinylaromatic compounds, wherein the modifiers are specific aminoethers.... | 06/24/2003 |
| 6562934 | Amino compound and process for producing the same An amino compound obtained by addition reaction of diamine represented by the following formula (1) and an alkenyl compound and a process for producing the same. H2 N--H2 C--A--CH2 --NH2 (1) wherein A is a phenylene... | 05/13/2003 |
| 6448445 | Method for catalytically disubstituting carboxylic acid amides with at least one grignard reagent The invention relates to a method for disubstituting carboxylic acid amides on the geminal carbonyl-C-atom using at least one grignard reagent in the presence of a metal alcoholate compound used as a catalyst and in the presence of another organometallic ... | 09/10/2002 |
| 6369274 | Method for producing cyclohexanediamines 1,n-cyclohexanediamines (n=2, 3, 4) of general formula (I), wherein one of the radicals R1 to R3 is an amino group and the two others mean hydrogen, are produced from the corresponding cyclohexanediols and ammonia in the presence of ... | 04/09/2002 |
| 6242641 | Cycloaliphatic compounds The present invention relates to compounds selected from formula I ##STR1## wherein R1, R2, R3 and R4 are the same or different and represent hydrogen, C1, to C6 -alkyl, C5 to C6... | 06/05/2001 |
| 6232501 | Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines This invention relates to a process for the cis-selective preparation of cyclic amines of the sertraline type by reductive alkylation of cyclic immines or of their precursors and for the catalytic hydrogenation in the presence of copper-containing catalys... | 05/15/2001 |
| 6172116 | Use of aminoadamantane compounds as immunoregulators wherein R1, R2, R3 and R4 are selected independently from each other from --NR5 R6, --NR5 R6 R7+, hydrogen, aryl or heteroaryl with up to 7 ring membe... | 01/09/2001 |
| 6111140 | Ru--Pd halogen-free catalyzers and method for producing cycloaliphatic amines Catalysts containing ruthenium and palladium for the hydrogenation of aromatic amines to cycloaliphatic amines. Methods for making and using the catalysts.... | 08/29/2000 |
| 6069176 | Phenylethanolamine compounds useful as ଲ 3 agonists, process for producing the same, and intermediates in the production of the same The present invention relates to phenylethanolamine compounds represented by general formula [I]: ##STR1## (where R1 represents hydrogen or halogen; R2 represents hydrogen, hydroxy, lower alkoxy, lower alkoxy substituted with on... | 05/30/2000 |
| 6034134 | 1-Amino-alkylcyclohexane NMDA receptor antagonists Certain 1-aminoalkylcyclohexanes are systemically-active uncompetitive NMDA receptor antagonists having rapid blocking/unblocking kinetics and strong voltage-dependency and are therefore useful in the alleviation of conditions resulting from disturbances ... | 03/07/2000 |
| 6013838 | Chemical intermediates bearing a trifluoromethyl group Novel trifluoromethylated intermediates are provided which are useful in synthesizing trifluoromethylated organic compounds. Specifically, compounds of the formula CF3 CR are provided, wherein R is (Cl).dbd.CHCH2 SO2 Ph, (... | 01/11/2000 |
| 5923044 | Lithium dialkylamide and lithium alkylenecycloimide formulations and methods of preparation A process for producing nornally liquid hydrocarbon solutions of lithium dialkylamides and lithium alkylenecycloimides, essentially free of ethers and by-product gaseous alkanes derived from C1-C4 alkyllithium compounds, comprising reacting lithium metal ... | 07/13/1999 |
| 5814616 | Administration of valienamine-related disaccharide compounds in reducing inflammation in a sensitized mammal arising from exposure to an antigen The present invention is directed to methods of reducing the degree of inflammation arising from a secondary immune response in a mammal due to antigen exposure (challenge) by the administration of valienamine-related disaccharide compounds and the pharma... | 09/29/1998 |
| 5801202 | Amine derivatives for treatment of skin disorders Disclosed is an amine derivative represented by the following formula (1) or an acid addition salt thereof: ##STR1## wherein R1 represents a group ##STR2## a cyclopentyl group, cyclohexyl group, or a cycloheptyl group, R2 i... | 09/01/1998 |
| 5773617 | Deallylation reagent and deallylation method using said reagent The present invention relates to a reagent and to a process which are useful, when carrying out an organic synthesis, for cleaving an allylic group from a function which is protected with the latter. This reagent is defined in that it contains: a) a solvent sy... | 06/30/1998 |
| 5741928 | Process for producing bis (aminomethyl) cyclohexane Disclosed is a process for producing bis(aminomethyl)cyclohexane, which comprises hydrogenating a xylylenediamine in the presence of a catalyst and at least one solvent selected from the group consisting alkylamines and alkylenediamines.... | 04/21/1998 |
| 5739405 | Preparation of amines from olefins over zeolites of the type SSZ-37 A process for the preparation of amines of the general formula I ##STR1## in which R1, R2, R3, R4, R5, R6 denote hydrogen, C1 -C20 alkyl, C2 -C20... | 04/14/1998 |
| 5726308 | High purity formulations of highly substituted lithium amide bases A process for preparing high purity solutions of highly substituted lithium amide bases by direct reaction of lithium metal with highly substituted amine bases alone or in an ether solvent, a hydrocarbon solvent or in a mixed ether/hydrocarbon solvent mix... | 03/10/1998 |
| 5719280 | Benzocycloalkylazolethione derivatives and processes for preparing the same The present invention relates to novel benzocycloalkylazolethione compounds which are dopamine ଲ-hydroxylase inhibitors in which the benzocycloalkyl portion of the compound is selected from indanyl, 1,2,3,4-tetrahydronaphthalenyl and 6,7,8,9-te... | 02/17/1998 |
| 5693864 | Process for the production of secondary amine terminated polyethers Disclosed herein is a process for preparing an amine terminated polyether comprising reacting a polyether containing a leaving group with a primary amine or ammonia at a temperature of about 70 to 250 degrees Centigrade.... | 12/02/1997 |
| 5665877 | Synthesis of bisindolylmaleimides The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because i... | 09/09/1997 |
