Class 564/460 - Bicyclo ring system

Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the polycyclo ring system is bicyclo.
No. of patents: 42
Last issue date: 03/20/2012

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Number	Title	Issue Date
8138377	Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use The invention provides novel arylbicyclo[3.1.0]hexylamines, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disor...	03/20/2012
7101916	Exo-S-mecamylamine formulation and use in treatment A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in combination with a pharmaceutically acceptable carrier. Preferably the amount is...	09/05/2006
6649658	(-)-Verbenone derivatives A description is given here of novel solid and stable derivatives of (-)-verbenone having formula (I) wherein, when X=O Z=H, .dbd.CHAr, .dbd.C(OH)COOEt, .dbd.NOR; Y=H, NH2, NH3 +X1 -, NHCOAr, NHCOR, NHCONHR, NHCONHAr, X	11/18/2003
6635783	Bicyclic 1,3-aminoalcohols, d8-metal complexes and hydrogenation processes Bicyclic amino alcohols, whose amino group and hydroxy group are bonded in positions 1,3 adjacent to the bridge, for example ##STR1## are valuable ligands for metal complexes of the d-8 metals of the periodic table of elements. The metal complexes in ques...	10/21/2003
6166234	Tripodal cyclopentadiene derivatives and their use Novel tripodal cyclopentadiene derivatives have the formula (I) ##STR1## where E are identical or different and are --N(R)(R), --P(R)(R), --As(R)(R), --Sb(R)(R), --OR, --SR, --SeR, --TeR, where R are identical or different and are each hydrogen, a C	12/26/2000
6137019	Process for converting a geminally substituted cyclopentadiene Process for converting a geminally substituted cyclopentadiene containing 2-6 substituents into a non-geminally substituted cyclopentadiene by reacting the geminally substituted cyclopentadiene with a base, sodium or potassium at a temperature of 0-200° ...	10/24/2000
6114392	Agmatine, and polyaminoguanidine-bound heterocyclic compounds for neurotrauma and neurodegenerative diseases The invention relates to the use of agmatine, in the treatment of acute neurotrauma (such as stroke) and degenerative disorders of the central and peripheral nervous system (such as dementia). The invention further provides novel compounds of general formula I...	09/05/2000
6025328	Antitumor agents The present invention provides illudin analogs of the general formula I: ##STR1## wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceuticall...	02/15/2000
5986142	Process for preparing bicycloheptanamine compounds The present invention provides a process for preparing compounds of Formula I: ##STR1## wherein R1 is methyl by reduction of a camphene intermediate with a reducing agent....	11/16/1999
5763647	Preparation of optically active 1,4-bridged-cyclohexane carboxylic acid derivatives A process for preparing an optically active 1,4-bridged-cyclohexane carboxylic acid derivatives which are clinically important thromboxane A2 thromboxane of formula (IV): ##STR1## wherein, R is phenyl or phenyl substituted with hydroxy, lo...	06/09/1998
5719280	Benzocycloalkylazolethione derivatives and processes for preparing the same The present invention relates to novel benzocycloalkylazolethione compounds which are dopamine ଲ-hydroxylase inhibitors in which the benzocycloalkyl portion of the compound is selected from indanyl, 1,2,3,4-tetrahydronaphthalenyl and 6,7,8,9-te...	02/17/1998
5610300	Carbocyclic nucleosides containing bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates Compounds of the formulae I and Ia and their racemates ##STR1## in which A is --CH2 -- or --CH2 CH2 --, R1 is hydrogen or a protective group, R2 is hydrogen or a protective group or a radical for...	03/11/1997
5461152	Carbocyclic nucleosides containing bicycle rings, oligonucleotides therefrom, process for their preparation, their use and intermediates Compounds of the formulae I and Ia and their racemates ##STR1## in which A is --CH2 -- or --CH2 CH2 --, R1 is hydrogen or a protective group, R2 is hydrogen or a protective group or a radical for...	10/24/1995
5284976	Method of producing primary amines in high yields A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and RNH2 in high yields from novel intermediates RBMe2 or RBMe2 wherein R is an organo group, R* is a chiral...	02/08/1994
5276195	Process for producing dimethylorganoboranes A process for preparing a dimethylorganoborane represented by the formula RBMe2 wherein R is a chiral organyl group attached to the boron, B is boron and Me is methyl comprising treating a chiral boronic ester R*B(OR')2 with a meth...	01/04/1994
5254707	Preparation of cyclopentadiene derivatives The process for preparing a compound of the formula: Cp'YNHR wherein: Cp' is a cyclopentadienyl or a substituted cyclopentadienyl group, Y is a covalent bridging group which contains one or more group 14 elements, and R is a C1 to C20 hyd...	10/19/1993
5243080	Method of fluorinating by using N-fluoropyridinium pyridine heptafluorodiborate The present invention provides a novel compound represented as ##STR1## The present novel compound is prepared by reacting fluorine with pyridine-boron trifluoride and is useful as a fluorinating agent in the fluorination of organic compounds....	09/07/1993
5214209	Method of producing primary amines in high yields and novel intermediates therefor A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and RNH2 in high yields from novel intermediates RBMe2 or RBMe2 wherein R is an organo group, R* is a chiral...	05/25/1993
5210310	Optically active dimethylorganoboranes A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and RNH2 in high yields from novel intermediates RBMe2 or RBMe2 wherein R is an organo group, R* is a chiral...	05/11/1993
5196542	Cyclic hydrocarbons with an aminoalkyl sidechain Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity....	03/23/1993
5084592	Azulenesquaric acid dyes, azulene intermediates therefor, and optical recording medium Azulenesquaric acid dyes of the formula ##STR1## where R1, R2, R3, R4 and R5 each have specified meanings are prepared from azulene derivatives of the formula ##STR2## where R1, R...	01/28/1992
5041673	Novel tetralin derivatives This invention relates to novel derivatives of tetralin, to the processes for their preparation, to their use as aminopeptidase inhibitors and to their end-use application as immunomodulators and as analgesic agents....	08/20/1991
4812543	Co-polymer-bound amine antioxidants A novel metathesis catalyst polymerizable composition is provided which comprises at least one ring-opening metathesis catalyst polymerizable norbornene-type monomer and at least one ring-opening metathesis catalyst polymerizable amine antioxidant comonom...	03/14/1989
4804659	Decahydronaphth-2-yl-alkylamines Novel fungicidally active decahydronaphth-2-yl-alkylamines of the formula ##STR1## in which A represents optionally substituted decahydronaphth-2-yl and R1 and R2 are identical or different and represent alkyl or alkenyl, or R1	02/14/1989
4716248	Aminocyclohexyl-substituted, branch alkylamines New compounds having the formula: wherein p is 1 or 2 and the residues QNH2 are the same or different and each is a residue of formula: ##STR1## wherein n is an integer from 1 to 15; R1 is C1 -C8 alkyl; R	12/29/1987
4472292	Liquid crystalline dielectric, new dichroitic naphthoquinone dyestuffs and electro-optical indicator element A liquid crystalline dielectric useful in electro-optical display elements based on the guest-host effect, comprises a liquid crystalline compound and a pleochroitic dyestuff of the formula ##STR1## wherein X and Y are the same or different and each ...	09/18/1984
4376217	Cobalt alkylnitroso complexes and methods therewith This invention provides a general method for the conversion of alkenes to primary vicinal diamines by use of a cobalt alkylnitroso complex and reduction with lithium aluminum hydride. A preferred species has the structure ##STR1##...	03/08/1983
4365085	Bicyclic reductone developing agents The present invention relates to novel bicyclic compounds useful as photographic silver halide developing agents, to the preparation of these compounds and to photographic products, processes and compositions employing the same. The subject compounds may ...	12/21/1982
4332969	Substituted 11-aminoundecanols Novel substituted 11-aminoundecanols of the formula ##STR1## and a process for their preparation are described; in the formula, R1 and R3 independently of one another are hydrogen or alkyl having 1-8 C atoms and R2 an...	06/01/1982
4288625	Dinitriles, diamines, and polyamides Unsaturated dinitriles are reacted with an aromatic compound such as benzene in the presence of a Lewis acid such as aluminum chloride to yield novel aralkylenedinitriles, such as 5-methyl-5-phenylnonanedinitrile and isomers thereof. The aralkylenedinitri...	09/08/1981
4275237	Hydrogenated polynitrile mixture useful as an epoxy hardener Heavy reaction product after separation as by distillation of light reaction product or diadduct from a reaction mixture obtained by reaction of olefinically unsaturated nitriles with monoolefinic hydrocarbons containing an allylic hydrogen atom is hydrog...	06/23/1981
4256667	2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI₂ compounds The present invention provides novel 2-decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications....	03/17/1981
4238414	2-Decarboxy-2-aminomethyl-6a-carba-PGI₂ compounds The present invention relates to novel 2-decarboxy-2-aminomethyl-6a-carba-PGI2 compounds, which are useful for inducing a variety of prostacyclin-like pharmacological effects. Accordingly, these compounds are useful pharmacological agents for t...	12/09/1980
4220650	Organic diamine therapeutic compositions and methods A series of organic diamine base compounds derived from either an aromatic, alicyclic or heterocyclic ring and possessing, for the most part, an intervening methylene group between the ring and the aforesaid basic moiety have been prepared, including thei...	09/02/1980
4189575	Halogenated spiro compounds Halogenated spiro compounds of the formula: ##STR1## wherein X is Cl, Y is Cl, p-chlorophenoxy, ##STR2## or ##STR3## wherein R is H, R1 is H, alkyl, alkenyl, cycloalkyl, aralkyl, aryl, or m-bromophenyl. The compounds accordi...	02/19/1980
4154611	Bicyclic reductone developing agents The present invention relates to novel bicyclic compounds useful as photographic silver halide developing agents, to the preparation of these compounds and to photographic products, processes and compositions employing the same. The subject compounds may ...	05/15/1979
4087551	Amino-bicycloheptanes Pharmaceutical compositions are described in which the active ingredient is a 7,7-dimethyl-[2,2,1]-bicycloheptane having at the 1-position a substituted or unsubstituted amino or aminomethyl group. The active ingredients have been found to possess antivir...	05/02/1978
4053511	Nopinylamines The nopinylamines of the general formula I ##STR1## where R1 and R2 are hydrogen or alkyl of 1 to 5 carbon atoms, and the salts of these amines with mineral acids and with alkylcarboxylic acids of 1 to 4 carbon atoms. The manufa...	10/11/1977
4032700	Process for the preparation of aminated polymers useful as additives for fuels and lubricants Preparation of aminated polymeric additives useful as oil additives, for example as dispersants for hydrocarbon fuels and lubricants, and as multifunctional dispersant-viscosity index improvers for lubricants, by the reaction of amine with a halogen conta...	06/28/1977
3988362	Intermediates for preparation of 2,2,3-endotrimethyl-7-anti-amino-norbornanes The present disclosure relates to intermediates 2,2,3-endo-trimethyl-7-anti-amino-norbornanes and N-substituted analogs thereof. In particular the aforesaid compounds have a conventional protective group on the amino moiety and also hydroxymethyl or ...	10/26/1976

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Class 564/460 - Bicyclo ring system