...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7538252 | Drug design for tubulin inhibitors, compositions, and methods of treatment thereof The present invention relates to a computer-assisted method of a designing of a tubulin inhibitor comprising: a) determining an interaction between a tubulin protein and a chemical known to bind the tubulin protein by evaluating a binding of the tubulin protein to t... | 05/26/2009 |
| 7226949 | Compounds of use in the treatment of epilepsy, seizure, and electroconvulsive disorders The present invention provides pharmaceutical preparations and the uses thereof for preventing and/or treating seizures and other electroconvulsive disorders by administering a pharmaceutically effective amount of a therapeutic compound having the following formula ... | 06/05/2007 |
| 7223518 | Compositions and methods of use thereof Compositions and methods of use thereof are disclosed. One exemplary composition, among others, includes a polymer resin and a photoacid generator. In particular, the composition includes a polymer resin, wherein the polymer resin does not substantially absorb about... | 05/29/2007 |
| 7090958 | Positive photoresist compositions having enhanced processing time Novel compositions comprising photoactive polymers comprising a dinitrobenzyl group in conjunction with a photoacid generator are disclosed. In one embodiment, the photoacid generator is a diazide and/or a sulfonyl aceto carbonyl compound. The photoacid generators a... | 08/15/2006 |
| 6933411 | Aromatic diamine and polyimide thereof The aromatic diamine compound of the present invention is represented by the following formula (1), and from the aromatic diamine compound a polyimide having a repeating unit represented by the following formula (4), which has low-temperature adherability, can be ob... | 08/23/2005 |
| 6924348 | Polyamide acid and polyimide, and optical material A polyimide excelling in heat resistance, chemical resistance, water repellency, dielectric characteristics, electrical characteristics, and optical characteristics and a polyamide acid useful as the raw material therefor are provided. Specifically, a polyamide acid... | 08/02/2005 |
| 6921840 | SPECT imaging agents for serotonin transporters The present invention is directed to compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein X is hydrogen, Cl, Br, I, NO2, NR3R4 or —L—Ch; Y is hydrogen, —CH2OR5, —CH2N... | 07/26/2005 |
| 6809119 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases The invention relates to BCAT inhibitors and the use thereof for treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic la... | 10/26/2004 |
| 6664425 | Process for producing 1,3-bis(3-aminophenoxy)benzene 1,3-Bis(3-aminophenoxy)benzene effective, for example, as a raw material for highly heat-resistant polyimide is produced industrially at a high yield by a reaction between 1,3-difluorobenzene and an alkali metal salt of 3-aminophenol.... | 12/16/2003 |
| 6630540 | Covulcanizable anti-aging agents This invention relates to covulcanizable anti-aging agents which can be produced by the reaction of p-phenylenediamines, which are optionally substituted, and/or of sterically hindered phenols, with bifunctional alkyl, aryl and/or aralkyl compounds and by... | 10/07/2003 |
| 6596772 | Phosphate mimics and methods of treatment using phosphatase inhibitors The invention relates to trifluoromethyl sulfonyl and trifluoromethyl sulfonamido compounds and the physiologically acceptable salts and the prodrugs thereof. These compounds are expected to modulate the activity of protein tyrosine enzymes which are rela... | 07/22/2003 |
| 6552230 | Method for preparing 2-nitro-5-(phenylthio)-anilines The invention relates to a process for preparing 2-nitro-5-(phenylthio)anilines of formula (I) ##STR1## wherein R1 represents hydrogen, C1 -C8 -alkyl, C3 -C8 -cycloalkyl, C1 -C8 ... | 04/22/2003 |
| 6380423 | Colorless compounds The invention includes colorless compounds having a central core and at least two arms extending from the core. The core can comprise one or more atoms. The at least two arms have the formula ##STR1## In such formula, Z is a segment of one or more atoms; ... | 04/30/2002 |
| 6323243 | Tyrosine-derived compounds as calcium channel antagonists The present invention provides compounds that block calcium channels and have the Formula I: ##STR1## and pharmaceutically acceptable salts, esters, and pro-drugs thereof, wherein R1 and R2 are independently H, phenylcyclopentylcarbo... | 11/27/2001 |
| 6169206 | 4-(n,n-dialkylamino)aniline compound, photographic processing composition containing the same and color image-forming method 4-(N,N-Dialkylamino)aniline compounds of the following general formula (I): ##STR1## wherein R1 represents an alkyl group, an aryl group or a heterocyclic group, R2 to R5 each represent a hydrogen atom or a substituent, an... | 01/02/2001 |
| 6162832 | 2-Phenoxyaniline derivatives A 2-phenoxyaniline derivative represented by the formula: ##STR1## wherein R1 is a hydrogen atom or a lower alkoxy group, R2 is a halogen atom or a nitro group, and R3 is a hydrogen atom or a halogen atom, or a pharma... | 12/19/2000 |
| 6156801 | 2-phenoxyaniline derivatives A 2-phenoxyaniline derivative represented by the formula: ##STR1## wherein R1 is a hydrogen atom, an amino group or an NHCOR3 group, R2 is a halogen atom, an amino group, a cyano group, a C1-6 alkyl group, ... | 12/05/2000 |
| 6069278 | Aromatic diamines and polyimides based on 4,4'-bis-(4-aminophenoxy)-2,2' or 2,2',6,6'-substituted biphenyl This invention relates the novel diamines, the polyimide oligomers and the polyimides derived therefrom and to the method of preparing the diamines, oligomers and the polyimides. The thermoplastic polyimides derived from the aromatic diamines of this inve... | 05/30/2000 |
| 6037499 | Aromatic diamines and polyimides based on 4,4'-bis-(4-aminophenoxy)-2,2' or 2,2',6,6'-substituted biphenyl This invention relates the novel diamines, the polyimide oligomers and the polyimides derived therefrom and to the method of preparing the diamines, oligomers and the polyimides. The thermoplastic polyimides derived from the aromatic diamines of this inve... | 03/14/2000 |
| 6008413 | Process for recrystallizing 1,3-bis(aminophenoxy benzene) A process for purifying 1,3-bis(aminophenoxy benzene) (APB) on a manufacturing scale to at least 99.5% purity comprises the sequential steps of (a) forming the dihydrochloride salt of APB (hereinafter APB-HCl), (b) recrystallizing the APB-HCl from isoprop... | 12/28/1999 |
| 5977413 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds Disclosed is a method for producing bis(3-amino-4-hydroxyphenyl) compounds, which comprises reducing bis(3-nitro-4-hydroxyphenyl) compounds with hydrazines in the presence of a catalyst. The method produces bis(3-amino-4-hydroxyphenyl) compounds of high q... | 11/02/1999 |
| 5910578 | Phenylazoanilines Azo dyes of the formula ##STR1## where X is oxygen or a radical of the formula NR6, where R6 is hydrogen or substituted or unsubstituted C1 -C13 -alkyl, R1 is substituted or unsubstituted C1 | 06/08/1999 |
| 5865854 | BIS-(2-4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods The invention provides compositions and methods containing novel bis-(2,4-diaminophenoxy)benzene coupling compounds, and cosmetically acceptable salts thereof, for use with conventional primary intermediate dye compounds and oxidizing agents for the oxida... | 02/02/1999 |
| 5847218 | Sulfonium salts and chemically amplified positive resist compositions The invention provides a novel sulfonium salt having a substituted or unsubstituted arylsulfonate anion. The novel sulfonium salt minimizes the influence of deactivation by basic compounds not only at a resist surface, but also at a resist-substrate inter... | 12/08/1998 |
| 5840984 | Stabilization of (hydrocarbylthio) aromatic amines against odor formation Odor formation during storage of (hydrocarbylthio)aromatic amines due to formation and release of odoriferous sulfur-containing species such as dihydrocarbyldisulfides, is suppressed. To accomplish this, a small amount of N,N-dihydrocarbylhydroxylamine od... | 11/24/1998 |
| 5831127 | Bisaminothiophenol compound A novel bisaminothiophenol compound represented by the following general formula: ##STR1## where Rf is a perfluoroalkylidene group having 1 to 10 carbon atoms, is used as a cross-linking agent for fluorine-containing elastomers having CN groups ... | 11/03/1998 |
| 5776951 | Anti-atherosclerotic diaryl compounds The present invention is concerned with diaryl compounds of formula (l) and their use in medical therapy, particularly in the prophylaxis or treatment of a clinical condition for which an ACAT inhibitor is indicated, such as hyperlipidaema or atherosclero... | 07/07/1998 |
| 5750789 | Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor An unsaturated imide compound represented by formula (1): ##STR1## wherein Q is an alicyclic structure-containing hydrocarbon group having 4-20 carbon atoms; each of R1, R2, R3, R4, Ri and R... | 05/12/1998 |
| 5696167 | 4-mercaptobenzoylguanidine derivatives 4-Mercaptobenzoylguanidines of the formula I ##STR1## in which A, R1, R2 and R3 have the meanings given, and the physiologically unobjectionable salts thereof exhibit antiarrhythmic properties and are active as inhibi... | 12/09/1997 |
| 5689004 | Diamines containing pendent phenylethynyl groups Controlled molecular weight imide oligomers and co-oligomers containing pendent phenylethynyl groups (PEPIs) and endcapped with nonreactive or phenylethynyl groups have been prepared by the cyclodehydration of the precursor amide acid oligomers or co-olig... | 11/18/1997 |
| 5675039 | Bis-m-benzotrifluoride compounds Disclosed are bis-meta-benzotrifluoride compounds having the general formula ##STR1## where each A is independently selected from the group consisting of NO2, NH2, and NH3+ Z-, Z- is ... | 10/07/1997 |
| 5637119 | Substituted aromatic polyalkyl ethers and fuel compositions containing the same Substituted aromatic polyalkyl ethers having the formula: ##STR1## wherein R1 is a polyalkyl group having an average molecular weight of about 450 to about 5,000; A is nitro, amino, cyano, aminomethyl, N-alkylamino or N-alkylaminomethyl wh... | 06/10/1997 |
| 5599993 | Phenylethynyl amine Four phenylethynyl amine compounds--3 and 4-aminophenoxy-4'-phenylethynylbenzophenone, and 3 and 4-amino-4'-phenylethynylbenzophenone--were readily prepared and were used to endcap imide oligomers. Phenylethynyl-terminated amide acid oligomers and ph... | 02/04/1997 |
| 5569784 | Sulfonium salt and resist composition A novel sulfonium salt having at least one substituted aromatic group having acid labile groups and at least one nitrogenous aromatic group is provided. A chemically amplified, positive resist composition comprising the sulfonium salt as well as an alkali... | 10/29/1996 |
| 5545444 | Diamino compounds and liquid crystal aligning films The present invention is to provide new diamino compounds useful for raw materials for production of liquid crystal aligning films that have excellent aligning properties and uniform and high pretilt angles over the whole display surface of wide substrate... | 08/13/1996 |
| 5440009 | Recovery of cyclic arylene sulfide oligomers A method for recovering cyclic oligomers from a poly(arylene sulfide) polymer or poly(arylene sulfide) polymerization reaction mixture is provided in which the cyclic oligomers are maintained in a solution comprising a suitable solvent and the cyclic olig... | 08/08/1995 |
| 5434308 | Method for the manufacture of 3,4'-diaminodiphenyl ether A method of dehydrogenating 3-amino-2-cyclohexene-1-one with a supported palladium or palladium-platinum catalyst in a solvent in the presence of base to produce 3-aminophenol and its use directly without purification to produce 3,4'-oxydianiline.... | 07/18/1995 |
| 5430195 | Diamino compounds and liquid crystal aligning films The present invention is to provide new diamino compounds useful for raw materials for production of liquid crystal aligning films that have excellent aligning properties and uniform and high pretilt angles over the whole display surface of wide substrate... | 07/04/1995 |
| 5426232 | Substituted tetracyanoquinodimethanes, processes for their preparation and their use Compounds of the formula I ##STR1## in which R1 and R2 independently of one another are C1 -C6 alkyl, C3 -C8 cycloalkyl which is unsubstituted or substituted by C1 -C4 | 06/20/1995 |
| 5414126 | Diamino compounds and liquid crystal aligning films The present invention is to provide new diamino compounds useful for raw materials for production of liquid crystal aligning films that have excellent aligning properties and uniform and high pretilt angles over the whole display surface of wide substrate... | 05/09/1995 |