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| Number | Title | Issue Date |
| 7473805 | Process for obtaining tolterodine The process comprises reacting a compound of formula (II), where R is a hydroxyl protecting group, and the asterisk indicates an asymmetric carbon atom, with diisopropylamine in the presence of a reducing agent; optionally converting the resulting intermediate into ... | 01/06/2009 |
| 7361789 | Dihydronaphthalene compounds, compositions, uses thereof, and methods for synthesis The present invention relates to novel dihydronaphthalene compounds, compositions, methods for using the same, and processes for preparing the same. The present invention also relates to novel total synthesis approaches for preparing these compounds. In addition, th... | 04/22/2008 |
| 7312362 | Process for the production of di- and polyamines of the diphenylmethane series The present invention relates to a process for the production of mixtures of di- and polyamines of the diphenylmethane series (MDA) containing less than 1,000 ppm of water and less than 200 ppm of aniline by reaction of aniline and formaldehyde in the presence of ac... | 12/25/2007 |
| 7235694 | Process for preparing 4-aminodiphenylamine A process for preparing 4-aminodiphenylamine having the steps of reacting nitrobenzene and aniline in the presence of a complex base catalyst, hydrogenating the reaction mixture with hydrogen, a powdery composite catalyst, and a hydrogenation solvent; separating, re... | 06/26/2007 |
| 7230134 | Method for the production of amines by reductive amination of carbonyl compounds under transfer-hydrogenation conditions This application claims the benefit of German priority Application No. 10138140.9, filed on Aug. 9, 2001, and International Application No. PCT/EP02/08748, filed on Aug. 6, 2002. The invention relates to the production of amines by the reaction of aldehydes or keton... | 06/12/2007 |
| 7183438 | Catalysts and method for the production of amines Disclosed are catalysts, the catalytically active mass of which contains 22 to 40 percent by weight of oxygen-containing compounds of zirconium, calculated as ZrO2, 1 to 30 percent by weight of oxygen-containing compounds of copper, calculated as CuO, 15 ... | 02/27/2007 |
| 7176332 | Methods for the synthesis of amines such as ephedrine and intermediates A method for the preparation of a compound of formula (VI): in which R2 is an optionally substituted C1–C6 alkyl; R4 is H, OH, an optionally substituted C1–C6 alkyl or an optionally substituted C1–C6 alkoxy; R5 is an optionally... | 02/13/2007 |
| 7176333 | Process for preparing 4-aminodiphenylamine The present invention discloses a process for preparing 4-aminodiphenylamine, which process uses nitrobenzene and aniline as raw materials, a complex base catalyst as condensation catalyst and a powdery composite catalyst as hydrogenation catalyst, and comprises fiv... | 02/13/2007 |
| 7084302 | Process for preparing 4-aminodiphenylamine A process for preparing 4-aminodiphenylamine using nitrobenzene and aniline as raw materials, a complex base catalyst as the condensation catalyst, and a powdery composite catalyst as the hydrogenation catalyst. The process has 5 process stages including condensatio... | 08/01/2006 |
| 7081551 | Optically active (R)-1-(4-trifluoromethylphenyl)ethylamine Optically active (R)-1-(4-trifluoromethylphenyl)ethylamine is a novel compound as an important intermediate for medicines and agricultural chemicals. This compound can be obtained with high optical purity and high yield by a process including the steps of (a) a dehy... | 07/25/2006 |
| 7078475 | Synergistic amine chain-extenders in polyurea spray elastomers Disclosed are derivatives of isophorone diamine exhibiting a synergistic relationship with other commonly employed chain extenders offering enhanced efficacy with regard to slowing of the polyurea elastomer cure profile, and processes employing their use. According ... | 07/18/2006 |
| 7074962 | Catalyst holder and agitation system for converting stirred tank reactor to fixed bed reactor This invention relates to apparatus particularly a monolith catalytic reactor in a stirred tank reactor. The stirred tank reactor including the fixed bed catalytic reactor apparatus comprises: an housing having an open top and open... | 07/11/2006 |
| 7034186 | Preparation of an amine Process for preparing an amine by reacting a primary or secondary alcohol, aldehyde or ketone with hydrogen and a nitrogen compound selected from the group consisting of ammonia and primary and secondary amines in the presence of a catalyst whose preparation has inv... | 04/25/2006 |
| 6696608 | Transfer hydrogenation process A catalytic transfer hydrogenation process is provided. The process can be employed to transfer hydrogenate N-substituted imines and iminium salts, which are preferably prochiral. The catalyst employed in the process is preferably a metal complex with one... | 02/24/2004 |
| 6696609 | Process for producing diamines A process for producing diamines which comprises the steps of: (1) reacting a dialdehyde with ammonia and hydrogen in the presence of an alcohol and a hydrogenation catalyst to synthesize the corresponding diamine; (2) separating and recovering the alcoho... | 02/24/2004 |
| 6689914 | Preparation of amines The preparation of amines of the formula (I): R1 R2 CH--N R3 R4 (I) in which R1, R2, R3 and R4, independently of one another, are hydrogen, straight-chain or branched C1 | 02/10/2004 |
| 6689913 | Process for preparing terbinafine and HCI salt thereof Provided is a process for preparing terbinafine or its HCl salt comprising: reacting a furan derivative with a base to form a second compound; performing a reductive alkylation of the second compound obtained in the step with N-methyl-1-naphthalenemethyla... | 02/10/2004 |
| 6642420 | Method for producing aldehydes and/or alcohols or amines A process for the preparation of aldehydes and/or alcohols or amines by reacting olefins in the liquid phase with carbon monoxide and hydrogen, a part of these gases being dispersed in the form of gas bubbles in the reaction liquid and another part being ... | 11/04/2003 |
| 6583320 | Process for preparing 4-aminodiphenylamine intermediates The invention is directed-to a method of producing one or more 4-aminodiphenylamine intermediates comprising the steps of bringing an aniline or aniline derivative and nitrobenzene into reactive contact and reacting the aniline and nitrobenzene in a confi... | 06/24/2003 |
| 6525222 | Process for preparing amines Amines are prepared by reacting aldehydes or ketones at elevated temperature under elevated pressure with nitrogen compounds selected from the group of ammonia, primary and secondary amines, and with hydrogen in the presence of a catalyst, wherein the cat... | 02/25/2003 |
| 6479704 | Hydrogenation with monolith reactor under conditions of immiscible liquid phases The present invention relates to an improved for the hydrogenation of an immiscible mixture of an organic reactant in water. The immiscible mixture can result from the generation of water by the hydrogenation reaction itself or, by the addition of, water ... | 11/12/2002 |
| 6462236 | Preparation of amines Amines of the formula (I) R1 R2 CH--NR3 R4 (I) where R1, R2, R3 and R4 are each, independently of one another, hydrogen, straight-chain or branched C1 -C12 | 10/08/2002 |
| 6429335 | Reductive amination of aldehydes The present invention relates to a process for preparing amines of formula (I) R1 --CH2 --NH2 (I), wherein R1 represents optionally branched C1 -C12 -alkyl, C3 -C8 -cycloa... | 08/06/2002 |
| 6417353 | Preparing amines Amines are prepared by reacting aldehydes or ketones at elevated temperature under elevated pressure with nitrogen compounds selected from the group of ammonia, primary and secondary amines, and with hydrogen in the presence of a catalyst containing coppe... | 07/09/2002 |
| 6395933 | Process for preparing 4-aminodiphenylamine intermediates The invention is directed to a method of producing one or more 4-aminodiphenylamine intermediates comprising the steps of bringing an aniline or aniline derivative and nitrobenzene into reactive contact; and reacting the aniline and nitrobenzene in a conf... | 05/28/2002 |
| 6342079 | Primary intermediate for use in oxidative hair dyeing 1-(2,5-Diaminophenyl)ethanol useful as a primary intermediate for the oxidative dyeing of hair.... | 01/29/2002 |
| 6331649 | Process for producing trifluoromethylbenzylamines The present invention relates to a process for producing a trifluoromethylbenzylamine represented by the general formula (1). This process includes the step of reducing an oxime represented by the general formula (2), ##STR1## where R1 rep... | 12/18/2001 |
| 6320084 | Process for the preparation of glyceraldehyde and derivatives thereof The invention pertains to a process for the preparation of glyceraldehyde, or an acetal or a hemiacetal thereof, characterized in that 3-butene-1,2-diol is dissolved in a lower alkanol and is subjected to ozonolysis to obtain a 3-hydroperoxy-3-alkoxy-prop... | 11/20/2001 |
| 6232501 | Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines This invention relates to a process for the cis-selective preparation of cyclic amines of the sertraline type by reductive alkylation of cyclic immines or of their precursors and for the catalytic hydrogenation in the presence of copper-containing catalys... | 05/15/2001 |
| 6194615 | Crosslinkers based on dibenzalacetone derivatives The present invention relates to the composition, process of preparation, and use of novel derivatives prepared from 1,5-bis-(4'-carbomethoxyphenyl)-1,4-pentadien-3-one. These novel compositions can act as crosslinkers with polyfunctional monomeric, ... | 02/27/2001 |
| 6187957 | Preparation of amines Amines are prepared by reacting primary or secondary alcohols, aldehydes or ketones with nitrogen compounds selected from the group consisting of ammonia and primary and secondary amines at elevated temperatures and superatmospheric pressures in the prese... | 02/13/2001 |
| 6100395 | Reductive alkylation of secondary amines with hydrosilane A novel process for the production of tertiary amines by reductive alkylation of second amine using hydrosilane and a Lewis acid is disclosed. The novel process has applications in the preparation of imidazole-containing benzodiazepines, inhibitors of far... | 08/08/2000 |
| 6072085 | Imine hydrosilylation, uses and reagents related thereto The method of the present invention provides a simple general route to a wide range of secondary amines.... | 06/06/2000 |
| 5977411 | Catalytic hydrogeneration of nitrobenzene to 4-aminodiphenylamine in the presence of a hydroxyl compound and a solvent This invention provides a method for preparing 4-ADPA by charging nitrobenzene into a reaction zone under hydrogen pressure in the presence of a strong organic base and a catalyst for hydrogenation. The method provides the convenience and economy of a one... | 11/02/1999 |
| 5973205 | Process for the preparation of 1, 3-diaminopropane derivatives and intermediates useful in this process A process for preparing a compound of formula (I) or an addition salt thereof and/or a solvate thereof: ##STR1## wherein R1, R2, R4 and R5 are each independently C1-4 alkoxy and R3 is ... | 10/26/1999 |
| 5885538 | Method and composition for the regeneration of an aminal compound The present invention provides a method and composition regeneration of an aminal that has previously been reacted with a sulfide selected from hydrogen sulfide and mercaptans. The method includes contacting a scavenging mixture which includes an aminal, ... | 03/23/1999 |
| 5861535 | Reductive alkylation process to prepare tertiary aminoaryl compounds Tertiary aminoaryl compounds, such as N,N'dialkylaminoaryl compounds, are prepared using successive reductive steps without isolation therebetween, at high temperature and pressure. A nitroaryl compound is reduced using a ketone as both solvent and reacta... | 01/19/1999 |
| 5817876 | Preparation of N-alkyl-arylamines Preparation of an N-alkyl-arylamine of the formula ##STR1## in which Ar represents an aryl radical which is optionally monosubstituted or polysubstituted by at least one of halogen and in each case optionally substituted alkyl, alkoxy or alkoxycarbon... | 10/06/1998 |
| 5817698 | Substituted cycloalkylamine derivatives and their use as calcium channel antagonists A method of treatment of a condition or disease related to the accumulation of calcium in the brain cells of a mammal which comprises administering to a subject in need thereof an effective amount of a compound of formula (I), wherein X is O, S, C.dbd.O o... | 10/06/1998 |
| 5719298 | Methods of producing pantothenic acid derivative and its starting materials for producing the same A method of producing a pantothenic acid derivative of formula (I): ##STR1## wherein each of R1 and R2 is different, and is a branched aliphatic hydrocarbon group having 3 to 5 carbon atoms, or a phenyl group; or a straight chai... | 02/17/1998 |
