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| Number | Title | Issue Date |
| 7468460 | Method for producing amines from hydroxamic acids A method for producing unprotected or carbamate-protected amines of formulae (II) and (III) or R1—NH2 (II) or R1—NHCO2R2 (III) by reacting hydroxamic acids of formula (I) (R1 CONHOH) with a) alkyl... | 12/23/2008 |
| 7378555 | Method of synthesizing camptothecin-relating compounds The present invention is to prepare efficiently 2′-amino-5′-hydroxypropiophenone corresponding to the AB-ring part of camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE-ring part in order to provide efficiently CPT by the total synthesis... | 05/27/2008 |
| 7202384 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate The present invention relates to a process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate, in which 4-(2-nitrophenyl)-n-butyronitrile is converted to 4-(2-nitrophenyl)-n-butyric acid. ... | 04/10/2007 |
| 7202378 | Process for producing 5-nitro-3,4-dihydro-1(H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate The present invention relates to a process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate, in which 4-(2-nitrophenyl)-n-butyronitrile is converted to 4-(2-nitrophenyl)-n-butyric acid. ... | 04/10/2007 |
| 7094928 | Process for the synthesis of (±) 2-Amino-N-[2,(2,5-dimethoxy phenyl)-2-hydroxyethyl] acetamide monohydrochloride This invention relates to an improved process for synthesizing (±)-2-Amino-N-[2-(2,5-dimethoxyphenyl]-2-hydroxyethyl acetamide monohydrochloride in good yield and in a cost effective manner from 1-(2,5-dimethoxyphenyl)-2-bromoethanone by reacting the same with hexa... | 08/22/2006 |
| 7057071 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate The present invention relates to a process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate, in which 4-(2-nitrophenyl)-n-butyronitrile is converted to 4-(2-nitrophenyl)-n-butyric acid. ... | 06/06/2006 |
| 6900245 | Pharmaceutical composition comprising crystalline sibutramine methanesulfonate hemihydrate The present invention relates to a pharmaceutical composition for treating or preventing obesity, comprising novel crystalline sibutramine methanesulfonate hemihydrate of formula (I). The crystalline sibutramine methanesulfonate hemihydrate according to the present ... | 05/31/2005 |
| 6657085 | Process for the preparation of aniline compounds A process for the preparation of aniline compounds of formula: ##STR1## wherein n and R are as defined in claim 1, by reacting nitro compounds of formula: ##STR2## wherein n and R are as defined, with hydrazine at elevated temperature in the prese... | 12/02/2003 |
| 6552228 | Exchange and to the release of an amine from its carbamoyl fluoride The present invention relates to a process for the treatment of an aryl carbamoyl fluoride comprising in its molecule at least one perhalogenated aliphatic carbon, which carbon carries at least one halogen atom to be exchanged with fluorine. This process ... | 04/22/2003 |
| 6476266 | Diamino compound and production process for the same Provided is a diamino compound suitable for obtaining a polyimide which can form a liquid crystal alignment film capable of providing a liquid crystal display element, an intermediate therefor and a production process for the same. The above production pr... | 11/05/2002 |
| 6448446 | Synthesis of N,N-disubstituted-p-phenylenediamine An improved synthesis of N,N,-disubstituted-p-phenylene-diamine (DSPDA) preferably di-n-butyl-p-phenylenediamine is disclosed. The improvement rests on the discovery that DSPDA and its salts are extremely sensitive to oxygen so that once the product DSPDA... | 09/10/2002 |
| 6444851 | Process for the preparation of Midodrine The invention provides a process for the preparation of 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide of the formula 1 by hydrogenolysis of substituted 2-dibenzylamino-N-[2-(2',5'-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide having the fo... | 09/03/2002 |
| 6403833 | Single step hydrogenation of nitrobenzene to p-aminophenol The present invention provides a single step process for the preparation of p-aminophenol by hydrogenation of nitrobenzene in presence of an aqueous acid over a mono or bimetallic nickel catalyst at a temperature in the range of 80-120° C. for a period o... | 06/11/2002 |
| 6169187 | Process for recovery of ascorbic acid The invention provides a process for the recovery of ascorbic acid from a feed containing at least one precursor of ascorbic acid comprising converting the precursor into at least one product, the at least one product being ascorbic acid in an organic ext... | 01/02/2001 |
| 6121491 | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-OL or cericlamine (INN) Process for the preparation of cericlamine which consists: i) in arylating methacrylic acid with the diazonium chloride of 3,4-dichloroaniline, to obtain (+/-)2-chloro-3-(3,4-dichlorophenyl)-2-methylpropionic acid, ii) in aminating the acid with dimethyla... | 09/19/2000 |
| 5847217 | Process for the preparation of 2-amino-5-alkyl-phenols 2-Amino-5-alkyl-phenols, which are suitable as intermediates in the production of crop-protection agents or photographic couplers, can be prepared by subjecting 2-amino-5-alkyl-benzenesulphonic acids or their salts to alkaline hydrolysis.... | 12/08/1998 |
| 5693863 | Method for the production of E-1-4'- (2- Dimethylaminoethoxy) - Phenyl!-1-(3-Hydroxyphenyl) -2-Phenyl-1-Butene The present invention relates to methods for the production of E-1-4'-(2-dimethylaminoethoxy)-phenyl!-1-(3'-hydroxyphenyl)-2-phenyl-1-bu tene of formula (I) which comprises heating the compound of formula (II) in the presence of an organic solvent and HC... | 12/02/1997 |
| 5672753 | Method of producing racemic amino alcohols -oximino carboxylic acids or their esters are reduced with an alkali boron hydride and hydrogen chloride or sulfuric acid to yield racemic amino alcohols (e.g. (RS)-tert-leucinol).... | 09/30/1997 |
| 5486609 | Preparation of carbocylic M-aminohydroxyaromatics A process for preparing carbocyclic m-aminohydroxyaromatics comprises reacting the corresponding o-- or m-halohydroxyaromatics or metal salts thereof with primary or secondary amines in the presence of a base and in the presence or absence of a diluent.... | 01/23/1996 |
| 5471002 | Process for preparing trifluoromethylanilines A process for preparing trifluoromethylanilines of the formula (I), ##STR1## in which R1 and R2, independently of each other, are hydrogen, halogen, (C1 -C4) alkyl, hydroxyl, alkoxy, alkylthio, carboxyl, or... | 11/28/1995 |
| 5430188 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides A process for the preparation of 2-alkyl-6-methyl-N(1'-methoxy-2'-propyl)-aniline by catalytic reductive alkylation wherein at least one mole equivalent of methoxyacetone is reacted with one mole equivalent of 2-alkyl-6-methyl-aniline in a liquid med... | 07/04/1995 |
| 5354891 | Method of producing aromatic amine derivatives Disclosed is a method for producing aromatic amine derivatives in a high yield at a low price, which comprises inducing an aromatic hydroxamic acid derivative to undergo a rearrangement reaction under a mild condition in the presence of a base and a nitri... | 10/11/1994 |
| 5326911 | Process for the preparation of ortho-amides Ortho-amides of the formula ##STR1## can be prepared by reacting salts of the formula ##STR2## with alcoholates of the formula M1 OR1 (III) where the radicals R1 to R4 | 07/05/1994 |
| 5214170 | Radioisotope iodine-labeled 1 (or 24R), 25-dihydroxy vitamin D3 A novel 1 (or 24R), 25-dihydroxy vitamin D3 amino acid derivative of the formula ##STR1## wherein R1 is OH or --O--CO--A--NH2, and R2 and R3 are each selected from the group consisting of ... | 05/25/1993 |
| 5145958 | Process for the preparation of 2,4- or 2,6-dihalogeno-aniline 2,4- or 2,6-dihalogeno-aniline can be prepared by reacting an amino-benzoic acid ester of the formula ##STR1## in which R1, R2 and R3 have the meanings indicated in the description, with 2-2.5 moles of a chlorinating ... | 09/08/1992 |
| 5041563 | Rearrangement process A process for the manufacture of ascorbic acid from 2-ketogulonic acid esters (KGAE) utilizing amine salts of the latter is disclosed.... | 08/20/1991 |
| 4973758 | Process for the preparation of 1,5-dihydroxynaphthalene and 1,5-diaminonaphthalene The characteristic of the improved process for the preparation of 1,5-dihydroxynaphthalene and 1,5-diaminonaphthalene is to carry out the alkaline pressure hydrolysis of the disodium salt of naphthalene-1,5-disulphonic acid at temperatures from 270° to ... | 11/27/1990 |
| 4964876 | Blue anthraquinone disperse dyes and mixtures of blue disperse dyes The dye mixture mentioned in claim 1 or one of the dyes mentioned in claims 12 or 13 are used for the dyeing of polyester textile material.... | 10/23/1990 |
| 4855503 | Preparation of P,P'-oxybis(aniline) Oxybisaniline is prepared in high yield by reacting a hydroxylamine with a polycarboxylic diphenyl ether in the presence of an inorganic acid. The acid groups are directly converted to amine groups. By-products of the reaction are negligible.... | 08/08/1989 |
| 4804407 | Method for recovering cobalt from hexammine cobaltic (111) solutions A method is disclosed for recovering cobalt, which comprises adding ammonia to a cobalt chloride solution to a pH of from about 8.8 to about 9.6 with oxidation, to form hexammine cobalt (III) chloride, adding to the resulting solution of hexammine cobalt ... | 02/14/1989 |
| 4748277 | Process for the preparation of trifluoromethylanilines A process for the preparation of trifluoromethylanilines. Hydrolysis and exchange fluorination of a para-trihalomethyl benzene isocyanate or carbamyl halide are carried out in liquid hydrofluoric acid.... | 05/31/1988 |
| 4624937 | Process for removing surface oxides from activated carbon catalyst An improved process is provided for the selective production of secondary amines and primary amines by bringing together under reaction conditions a tertiary amine or a secondary amine with oxygen or an oxygen-containing gas in the presence of an activate... | 11/25/1986 |
| 4506039 | Process for the production of polymer-containing aromatic polyether polyamines Polymer-containing polyether polyamines containing terminal aromatically-bound amino groups are produced by in situ polymerization of a polyether polyamine with an olefinically unsaturated monomer. The polyether polyamine starting material must have termi... | 03/19/1985 |
| 4481370 | Method for the preparation of benzenamines A method for the preparation of aromatic amines comprises reacting hydrogen fluoride with a phenyl carbamic fluoride.... | 11/06/1984 |
| 4363766 | Process for the preparation of sulfur-containing N-benzyl-amino acids and esters A process for the preparation of sulfur-containing N-benzyl-amino acids of the formula ##STR1## wherein X and Y, which may be identical to or different from each other, are each hydrogen or halogen; R1 is hydrogen or alkyl of 1 to 4 carbon... | 12/14/1982 |
| 4299983 | Chemical process A process for the production of symmetrical and unsymmetrical substituted diarylamines is disclosed. The process provides said diarylamines in high yield and purity by the reaction of a salt of an arylsulfonic acid and an alkali metal salt of a primary ar... | 11/10/1981 |
| 4198522 | 4-(Monoalkylamino)phenyl carbinols and ester derivatives This disclosure describes 4-monoalkylaminophenyl carbinols (primary, secondary, and tertiary alcohols) and with derivatives and salts thereof useful as hypolipidemic and anti-atherosclerotic agents.... | 04/15/1980 |
| 4182877 | Substituted anthranilates Anthranilic acid derivatives exhibiting fungicidal properties and useful as synthesis intermediates have the formula: ##STR1## wherein R is selected from the group consisting of a hydrogen atom; a --COOR3 group and a --CH2 OH gr... | 01/08/1980 |
| 4180523 | Manufacture of N-[3,4-dimethylphenyl]-D-ribamine A process for the manufacture of N-[3,4-dimethylphenyl]-D-ribamine, in which (a) a mixture of 3,4-dimethylaniline and/or 3,4-dimethylnitrobenzene and a D-ribonic acid derivative of the formula ##STR1## where each R' is hydrogen or one of the R's toge... | 12/25/1979 |
| 4168279 | Manufacture of amines of the formula Ar--NH--CH2 --R Amines of the formula Ar--NH--CH2 --R, where Ar is unsubstituted or substituted phenyl and R is alkyl of 3 to 6 carbon atoms substituted by hydroxyl groups, are manufactured by catalytic hydrogenation of a salt of an acid of the formula R--COOH... | 09/18/1979 |
