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| Number | Title | Issue Date |
| 7432399 | Diols formed by ring-opening of epoxies A polyol monomer comprising the formula: R1 and R3 are —H, aliphatic, aromatic, or ether; R2 is aliphatic, aromatic, ester, ether, or acrylic, and R1 contains a hydroxyl group, ... | 10/07/2008 |
| 7230018 | Substituted propane-1,3-diamine derivatives and the pharmaceutical use thereof Substituted propane-1,3-diamine derivatives, methods for producing such derivatives, and medicaments and pharmaceutical compositions containing such derivatives useful for the treatment or prophylaxis of pain, urinary incontinence, itching, tinitus aurium, or diarrh... | 06/12/2007 |
| RE39530 | 3-amino-3-arylpropan-1-ol-compounds, their preparation and use 3-amino-3-arylpropan-1-ol compounds corresponding to the formula I in which R1 to R5, A and X have the meanings according to claim 1, and their preparation and use as medicaments. ... | 03/27/2007 |
| 7074970 | Process for producing vinyl ether compounds A process produces vinyl ether compounds and includes allowing a vinyl ester compound represented by following Formula (1): wherein R1, R2, R3 and R4 are the same or di... | 07/11/2006 |
| 6951958 | Solid phase parallel synthesis of tertiary amines Described is method for preparing tertiary amines comprising sequential, exhaustive alkylation of a hydroxylamine derivative and cleavage of the O—N bond using the following steps: a) reacting the hydroxylamine derivative with an alkylating agent or w... | 10/04/2005 |
| 6849767 | Method of hydroborating alcohols and reducing functional groups using a recyclable fluorous borane-sulfide A method of hydroborating an alkene or alkyne, or reducing an organic functionality, oxidizing primary and secondary alcohols using a fluorous borane-sulfide is disclosed. The method includes regeneration and recycling the fluorous borane-sulfide. ... | 02/01/2005 |
| 6765023 | Use of substituted N, N-disubstituted reverse aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atheroscle... | 07/20/2004 |
| 6759554 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or a... | 07/06/2004 |
| 6723753 | Substituted n-benzyl-n-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atheroscle... | 04/20/2004 |
| 6723752 | (R)-chiral halogenated substituted n-benzyl-n-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1 )-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for... | 04/20/2004 |
| 6713135 | Materials for inducing alignment in liquid crystals and liquid crystal displays The present invention provides novel polyimides, poly(amic acids) and poly(amide esters) thereof, and optical alignment layers derived therefrom, for inducing alignment of liquid crystals and liquid crystal displays. The novel compositions comprise side-chain polyme... | 03/30/2004 |
| 6683099 | Substituted N,N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/27/2004 |
| 6683113 | (R)-chiral halogenated substituted N,N-Bis-benzyl aminioalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and m... | 01/27/2004 |
| 6677380 | Substituted N, N-disubstituted mercapto amino compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/13/2004 |
| 6677375 | Substituted N,N-bis-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/13/2004 |
| 6515180 | Method for the catalytic, symmetric disubstitution of carboxylic acid amides with grignard reagents The invention relates to a method for symmetrically disubstituting carboxylic acid amides on the geminal carbonyl-C-atom using grignard reagents in the presence of a metal alcoholate compound used as a catalyst and in the presence of another organometalic... | 02/04/2003 |
| 6512145 | Method for the catalytic, asymmetric disubstitution of carboxylic acid amides with two different grignard reagents The invention relates to a method for asymmetrically disubstituting carboxylic acid amides on the geminal carbonyl-C-atom using two grignard reagents in the presence of a metal alcoholate compound used as a catalyst and in the presence of another organome... | 01/28/2003 |
| 6479661 | Method for symmetrically and asymmetrically disubstituting carboxylic acid amides with organotitanates and grignard reagents The invention relates to a method for disubstituting carboxylic acid amides on a geminal carbonyl-C-atom using a Grignard reagent in the presence of an organotitanate.... | 11/12/2002 |
| 6476075 | Use of substituted N, N-bis-benzyl aminoalcohol compounds inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 11/05/2002 |
| 6476057 | Use of substituted N, N-disubstituted cycloalkyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for t... | 11/05/2002 |
| 6476268 | Preparation of N-benzylamines N-Benzylamines are prepared by a process in which (i) in a first step, a benzaldehyde is reacted with a primary amine to give the imine and (ii) in a second step, the imine is hydrogenated with hydrogen in the presence of a catalyst containing one or more meta... | 11/05/2002 |
| 6465693 | Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed aryla... | 10/15/2002 |
| 6462092 | Use of substituted N, N-disubstituted reverse aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for t... | 10/08/2002 |
| 6458849 | use of substituted N,N-disubstituted mercapto amino compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkyamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for tr... | 10/01/2002 |
| 6429335 | Reductive amination of aldehydes The present invention relates to a process for preparing amines of formula (I) R1 --CH2 --NH2 (I), wherein R1 represents optionally branched C1 -C12 -alkyl, C3 -C8 -cycloa... | 08/06/2002 |
| 6380432 | Materials for inducing alignment in liquid crystals and liquid crystal displays The present invention provides novel aromatic diamines useful in preparing polyimides for optical alignment layers in liquid crystal displays. The novel compositions comprise side-chains general formula I --L1 --D--L2 --Cf wher... | 04/30/2002 |
| 6362372 | Process for producing trifluoromethylbenzylamines The invention relates to a process for producing a trifluoromethylbenzylamine represented by the following general formula (1), ##STR1## where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine... | 03/26/2002 |
| 6291713 | Process of transferring , ଲ-unsaturated alkyl groups to electrophiles There is described a process of transferring ,ଲ-unsaturated alkyl groups to an electrophile (aldehyde, ketone, nitrile, imine, alkyne) by means of a masked zinc alkyl in an aprotic solvent.... | 09/18/2001 |
| 6288278 | 3-amino-3-arylpropan-1-ol-compounds, their preparation and use 3-amino-3-arylpropan-1-ol compounds corresponding to the formula I ##STR1## in which R1 to R5, A and X have the meanings according to claim 1, and their preparation and use as medicaments.... | 09/11/2001 |
| 6235871 | Synthesis of oligoarylamines, and uses and reagents related thereto The transition metal-catalyzed amination of aryl halides, in conjunction with an orthogonal protective group scheme, forms the basis of two routes to oligoaniline precursors. The oligoaniline precursors are soluble in a variety of common organic solvents,... | 05/22/2001 |
| 6235936 | Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed aryla... | 05/22/2001 |
| 6232467 | Method for the synthesis of amines and amino acids with organoboron derivatives Amines and amino acids are prepared by reacting an amine, a carbonyl derivative, and an organoboron compound under mild conditions.... | 05/15/2001 |
| 6175041 | Process for producing trifluoromethylbenzylamines The invention relates to a process for producing a trifluoromethylbenzylamine represented by the following general formula (1). This process includes hydrogenating a trifliuoromethylbenzonitrile represented by the following general formula (2) by hydrogen... | 01/16/2001 |
| 6169200 | Method for producing -hydroxy-ଲ-aminocarboxylic acids The present invention provides a simple and inexpensive method for producing -hydroxy-ଲ-aminocarboxylic acids and their esters. An ester of an N-protected -amino acid ester is converted into a ଲ-ketosulfoxide, which is then processed ... | 01/02/2001 |
| 6169116 | Amino-tetralines, pharmaceutical compositions containing them and their pharmaceutical uses Compounds of formula I ##STR1## wherein R1, R2, R3, R4 and R5 are as defined in the description, are useful as pharmaceuticals.... | 01/02/2001 |
| 6127550 | Stereospecific preparation of chiral 1-aryl-and 1-heteroaryl-2-substituted ethyl-2-amines This invention is directed to methods for stereospecifically preparing [(1-optionally substituted aryl)- or (1-optionally substituted heteroaryl)]-2-substituted ethyl-2-amines, having chirality at the 2-position, and to intermediates to the substituted et... | 10/03/2000 |
| 6072085 | Imine hydrosilylation, uses and reagents related thereto The method of the present invention provides a simple general route to a wide range of secondary amines.... | 06/06/2000 |
| 6057358 | Amine derivatives, processes for producing them and a use of them as antiarrhythmic drugs Novel amine derivatives of the following general formula (I): ##STR1## (wherein) A may denote --(CH2)--O--, --(CH2)2 --O--, or --(CH2)2 --NH--; B may denote --(CH2)2 --; R1 | 05/02/2000 |
| 5929281 | Process for producing heterocyclic aromatic amine or arylamine A heterocyclic aromatic halide or an aryl halide is reacted with an amine compound in the presence of a base to give a heterocyclic aromatic amine or an arylamine, respectively. In this reaction, a catalyst comprising a palladium compound and a tertiary p... | 07/27/1999 |
| 5883284 | Method for producing -hydroxy-ଲ-aminocarboxylic acids The present invention provides a simple and inexpensive method for producing -hydroxy-ଲ-aminocarboxylic acids and their esters. An ester of an N-protected -amino acid ester is converted into a ଲ-ketosulfoxide, which is then processed ... | 03/16/1999 |
