Class 564/387 - The aryl ring or ring system is polycyclo

Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the aryl ring system is a polycyclo ring
No. of patents: 122
Last issue date: 05/26/2009

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Number	Title	Issue Date
7538250	Pyrene compound and organic light emitting device An object of the present invention is to provide a novel pyrene compound. Provided is a pyrene compound represented by the following general formula (I): wherein: R1 and R2 each represent a substituted...	05/26/2009
7288678	Process for preparing terbinafine by using platinum as catalyst A process for the preparation of terbinafine, comprising the reaction of a compound of formula (II), or a salt thereof, wherein X is a leaving group, with tert-butylacetylene, in the presence of a platinum catalyst ...	10/30/2007
7244703	Pharmaceutical compositions and methods for peptide treatment Compositions and methods for treating a patient with a pharmaceutically active peptide that combines a pharmaceutically active peptide, a permeation enhancer, and a carrier, are disclosed. ...	07/17/2007
7122184	Specific monoclonal antibody against terbinafine The invention concerns momoclonal antibodies to terbinafine in free base or salt form, immunogenic conjugates suitable for preparing them, hybridoma capable of producing them, and corresponding assay kits. The antibodies can be prepared by administering to an approp...	10/17/2006
7112561	Pharmaceutical compositions and methods for insulin treatment Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed. ...	09/26/2006
7022883	Preparation of aryl intermediates Disclosed are methods of making aryl intermediate compounds of the formula (A) which are useful in the production of heteroaryl ureas, Y and P are defined herein below. ...	04/04/2006
6919317	Pharmaceutical composition comprising squalene epoxidase inhibitor and macrolide immunomodulator Synergistic combinations of a squalene epoxidase inhibitor such as terbinafine and a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro, 33-desoxyascomycin are provided, which are useful in particular in the treatment of diseases involving fu...	07/19/2005
6787570	Substituted N-cycloalkyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted N-Alkyl/Alkenyl/Cycloalkyl/Heterocycyl N-Aryl/Heteroaryl tertiary-Heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and metho...	09/07/2004
6710089	Substituted N-fused-phenyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atheroscle...	03/23/2004
6689913	Process for preparing terbinafine and HCI salt thereof Provided is a process for preparing terbinafine or its HCl salt comprising: reacting a furan derivative with a base to form a second compound; performing a reductive alkylation of the second compound obtained in the step with N-methyl-1-naphthalenemethyla...	02/10/2004
6583183	Substituted n-phenyl-n-fused-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating...	06/24/2003
6515181	Process for the preparation of terbinafine A process for the preparation of terbinafine which comprises the reaction of tert-butylacetylene with a compound of formula (II) ##STR1## characterized in that the reaction is carried out in the presence of copper (I) salts and of a base, in the absence o...	02/04/2003
6495496	Hydroxy aromatic mannich base condensation products and the use thereof as soot dispersants in lubricating oil compositions Low molecular weight Mannich base condensates of hydroxy aromatic compounds, an aldehyde; and an amine, wherein the combined number of substituent carbon atoms does not exceed 80. Such compounds are useful as soot dispersants in lubricating oils when used...	12/17/2002
6448295	Use of substituted N-fused-phenyl-N-benzyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating...	09/10/2002
6252114	Process for preparing novel biologically active synthetic molecule 4-(p-methoxyphenyl)-2-amino-butane The invention provides a process for the preparation of 4-(p-methoxyphenyl)-2-aminobutane represented by structural formula (1) as shown herein below: ##STR1## [C11 H17 ON=4-(p-methoxy phenyl)-2-amino butane] said process comprising ...	06/26/2001
6114394	Polyamine derivatives as radioprotective agents The present invention relates to polyamine derivatives of the formula RHN-(CH2)m -NH-(CH2)n -NHR wherein m is an integer from 2 to 4, n is an integer from 3 to 10 and R is C2 -C6 alkyl or -...	09/05/2000
6001884	Calcium receptor-active molecules The present invention features molecules which can modulate one or activities of an inorganic ion receptor. Preferably, the molecule can mimic or block the effect of extracellular Ca2+ on a calcium receptor. The preferred use of such molecules...	12/14/1999
5981599	Inorganic ion receptor active compounds The present invention features compounds able to modulate one or more activities of an inorganic ion receptor and methods for treating diseases or disorders using such compounds. Preferred compounds can mimic or block the effect of extracellular calcium o...	11/09/1999
5817875	Methods for the manufacture of terbinafine Process for the manufacture of naphthylmethylamine derivatives and among them terbinafine as potential antimycotic agents....	10/06/1998
5808098	Optically active beta-aminoalkoxyborane complex 1. An optically active ଲ-aminoalkoxyborane complex of the formula (I): ##STR1## wherein R1 is C1 -C8 alkyl, C3 -C7 cycloalkyl, C7 -C11 aralkyl or C6 -C10	09/15/1998
5686616	Process for preparing an optically active amine A novel process for preparing an optically active amine by asymmetric hydrogenation of an imine compound, such as an imine compound prepared by condensing benzylamine and acetophenone, in the presence of a catalytic amount of an iridium-optically active p...	11/11/1997
5633405	Asymmetric synthesis of (-)-6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1- benzoxanzin-2-one An improved synthesis of a highly potent HIV reverse transcription inhibitor is disclosed, involving an acetylide and a trifluoromethyl ketone which produces a chiral product in the presence of a chiral amino alcohol....	05/27/1997
5571942	Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor....	11/05/1996
5508306	Aromatic amine derivatives This invention relates to novel aromatic amine compounds having the structure: ##STR1## where each W, Z1 and Z2 is independently H, C1 -C6 alkyl, C1 -C6 alkoxy, OH, F, Cl, Br, I, NO	04/16/1996
5436354	Intermediates for producing enyne derivatives (E)-N-(3-Chloro-2-propenyl)-N-methyl-1naphthylenemethanamine and (E)-3-chloro-N-(3-chloro-2-propenyl)-N-methylbenzo[b]thiophene-7-methanami ne which are useful as intermediates in the production of enyne compounds which exhibit squalene epoxidase inhibitin...	07/25/1995
5430063	Phenoxyphenyl derivatives, compositions thereof and methods for their use The invention concerns a phenoxyphenyl compound having the formula ##STR1## wherein R is one or two halogen atoms; and A is CH2 NR1 R2 or 4,5-dihydro-1H-imidazole, in which R1 and R2 are independently...	07/04/1995
5359091	Intermediates for producing enyne derivatives A compound of the formula: ##STR1## wherein R11 is hydrogen, lower alkyl, haloloweralkyl, lower alkenyl, lower alkynyl or cycloalkyl; R21 is a group of the formula: ##STR2## wherein each of R3, R31, an...	10/25/1994
5334628	Amine derivatives, processes for preparing the same and fungicides containing the same Amine derivatives having the general formula (I): ##STR1## wherein X is selected from the group consisting of ##STR2## wherein Q is oxygen, sulfur or nitrogen atom, and ##STR3## wherein Q is as above; Y is selected from the group consisting...	08/02/1994
5296612	Process for producing enyne derivatives A process for producing an enyne derivative, and intermediate, which is useful for preparing compounds showing strong inhibiting activities against squalane epoxidase of Eumycetes and strong anti-cholesterol activities. The process comprises reacting a co...	03/22/1994
5276053	Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed....	01/04/1994
5245028	Process for preparing tetracyclic amines useful as cerebrovascular agents Processes for the preparation of a series of tetracyclic amines useful in the treatment and/or prevention of cerebrovascular disorders are disclosed....	09/14/1993
5231183	Process for producing enyne derivatives A process for producing an enyne derivative, and intermediate, which is useful for preparing compounds showing strong inhibiting activities against squalane.epoxidase of Eumycetes and strong anti-cholesterol activities. The process comprises reacting a co...	07/27/1993
5216178	Process of reducing olefins Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds ar...	06/01/1993
5202486	Tetrahydroethanonaphthaleneamine derivatives Tetrahydronaphthaleneamine derivatives having the formula ##STR1## wherein R, R', R1 and R2 are as defined herein, are novel calcium channel blockers....	04/13/1993
5180746	Aralkylamine compounds An aralkylamine compound of the formula ##STR1## wherein R1 means a hydrogen atom or a lower alkyl group; R2 means an aromatic group which may be substituted; R3 means a hydrogen atom, a lower alkyl group or an aromat...	01/19/1993
5166438	1,3-pentadiene derivatives and electrophotographic photoconductor using the same A charge transporting material comprising a 1,3-pentadiene derivative having formula (I): A--CH.dbd.CH--CH.dbd.CH--CH2 --A (I) wherein A represents a 9-anthryl group which may have a substituent, a N-substituted carbazolyl group...	11/24/1992
5149714	Antidepressants The present invention provides novel aryloxy indanamines of the formula ##STR1## wherein n, p and q are each independently 0, 1 or 2, Y and X are each independently lower alkyl, lower alkoxy, hydroxy, CF3, halogeno or when p or q are 2 and each...	09/22/1992
5132459	Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals Compounds of formula I ##STR1## wherein R1 represents a group of formula ##STR2##...	07/21/1992
5117062	Aromatic tertiary amines, enamines, deoxybenzoins and benzils A novel synthesis of aromatic tertiary amines involves reacting an aromatic anil and an aromatic ether in a molar ratio of 1:1; adjusting the ratio to 2:1 produces novel enamines and by employing a two step process for enamine production, various unsymmet...	05/26/1992
5032616	4-substituted cyclohexylamine derivatives, fungicides containing these and a method of controlling fungi 4-trans-substituted cyclohexylamine derivatives of the formula ##STR1## where R1 is the group CR5 R6 R7, in which R5, R6 and R7 are hydrogen, unsubstituted or substituted alkyl, ...	07/16/1991

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Class 564/387 - The aryl ring or ring system is polycyclo