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| Number | Title | Issue Date |
| 7459586 | Optically active 1-aryl-2-fluoro-substituted ethylamine and method for producing same The present invention relates to a method of producing an optically active 1-aryl-2-fluoro-substituted ethylamine compound of the formula [2] or a salt thereof by hydrogenolysis of an optically active secondary amine compound of the formula [1] or a salt thereof in ... | 12/02/2008 |
| 7358398 | Methods of amination A method of synthesizing a compound of formula I: comprising the step of reacting a moiety of formula II: with a moiety of formula III: in compressed carbon dioxide in the presence of a transition metal catalyst and a base, wherein L is a labile leaving group; R | 04/15/2008 |
| 7321066 | Method for producing aromatic diamine derivative The invention provides a method for efficiently producing an aromatic diamine derivative represented by formula (3) at high yield, the method including reacting an aromatic amide represented by formula (1) with an aromatic halide represented by formula (2): | 01/22/2008 |
| 7183437 | Method for preparing three types of benzidine compounds in a specific ratio A method for preparing three types of benzidine compounds in a specific ratio, the method uses two types of diphenylamine compounds and one type of biphenyldihalide compound in a specific ratio as reactants to mix with an organic solvent and an additive to synthesiz... | 02/27/2007 |
| 7138548 | Process for the preparation of aryl hydrazone and aryl hydrazine A process for the preparation of a compound of formula (I): wherein Ar represents an optionally substituted aromatic carbocycle or heterocycle, and R1 and R2 independently represent hydrogen... | 11/21/2006 |
| 7119122 | Compounds for the inhibition of nitric oxide synthase There are provided novel compounds of formula (I) wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their prepara... | 10/10/2006 |
| 7102023 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries One aspect of the present invention relates to optionally substituted halogenated benzyl halides and the like. These compounds are useful as halogenated benzyl ether-based protecting groups for a variety of functional groups. Another aspect of the present invention ... | 09/05/2006 |
| 6969528 | Phosphorus-containing dendrimers as transfection agents The invention concerns phosphorus-containing dendrimers and their uses, as gene transfection agents, in vitro and in vivo, including in the treatment of human and animal diseases. These agents or vectors are in particular suited for delivering to appropriate target ... | 11/29/2005 |
| 6958204 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus An electrophotographic photosensitive member includes a charge generating material and a charge transfer material. The charge transfer material contains a triarylamine compound synthesized from an amine compound and an aryl halide in the presence of a catalyst compr... | 10/25/2005 |
| 6946577 | Process for the production of aminodiphenylamines The present invention relates to a process for the production of aminodiphenyl-amines, such as 4-aminodiphenylamine (4-ADPA), by reacting nitrohalogenated benzenes with anilines in the presence of a base as well as a copper-phosphorus complex, followed by hydrogenat... | 09/20/2005 |
| 6803462 | Process for synthesizing functionalized styrene monomer This invention discloses a rubbery polymer which is comprised of repeat units that are derived from (1) at least one conjugated diolefin monomer, and (2) at least one functionalized monomer having of the structural formula: ... | 10/12/2004 |
| 6770786 | Process for preparing a substituted allylamine derivative and the salts thereof The antifungal agent (E)-N-methyl-N-(1-naphthylmethyl)-6,6-dimethyl-hept-2-ene-4-ynyl-1-amine of formula (I) and acid addition salts thereof are prepared by reacting a chloro-compound of formula (IIIb) ... | 08/03/2004 |
| 6770785 | Antiozonant cum antioxidant, process for preparation The present invention relates to a novel antiozonant as well as antioxidant based on functionalized hindered phenol and the process for the preparation thereof of formula 1 wherein R1 is tert-butyl and R2... | 08/03/2004 |
| 6759554 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or a... | 07/06/2004 |
| 6713652 | Process for hydrolyzing optically active amides The present invention relates to a process for hydrolyzing optically active amides to carboxylic acids and optically active amines with retention of the center of chirality, where the hydrolysis of the amides is carried out with an alkali metal or alkaline earth met... | 03/30/2004 |
| 6710210 | N-substituted-aminomethyl cyclopropyl ketone derivatives or salts thereof and production process therefor Novel N-substituted-aminomethyl cyclopropyl ketone derivatives are represented by following Formula (1): wherein R1, R2 and R3 are each a hydrogen atom or an aliphatic hydrocarbon group; ... | 03/23/2004 |
| 6670471 | Process for synthesizing functionalized styrene monomer This invention discloses a rubbery polymer which is comprised of repeat units that are derived from (1) at least one conjugated diolefin monomer, and (2) at least one functionalized monomer having of the structural formula: ##STR1## wherein R represe... | 12/30/2003 |
| 6476268 | Preparation of N-benzylamines N-Benzylamines are prepared by a process in which (i) in a first step, a benzaldehyde is reacted with a primary amine to give the imine and (ii) in a second step, the imine is hydrogenated with hydrogen in the presence of a catalyst containing one or more meta... | 11/05/2002 |
| 6465693 | Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed aryla... | 10/15/2002 |
| 6423871 | Efficient synthesis of secondary amines by selective alkylation of primary amines A method for selective mono-N-alkylation of primary amines to produce secondary amines that are substantially free of overalkylated tertiary amines and quaternary ammonium salts, under mild reaction conditions without the necessity of protecting groups. C... | 07/23/2002 |
| 6235871 | Synthesis of oligoarylamines, and uses and reagents related thereto The transition metal-catalyzed amination of aryl halides, in conjunction with an orthogonal protective group scheme, forms the basis of two routes to oligoaniline precursors. The oligoaniline precursors are soluble in a variety of common organic solvents,... | 05/22/2001 |
| 6235936 | Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed aryla... | 05/22/2001 |
| 6137009 | Method of manufacturing flumetralin The invention is a process to manufacture the intermediate secondary amine N-ethyl-2-chloro-6-fluoro-benzylamine, and then the process of reacting this intermediate to manufacture the herbicide flumetralin. Equimolar quantities of monoethylamine, sodium h... | 10/24/2000 |
| 6100398 | Transition metal-catalyzed process for preparing N-aryl amine compounds Disclosed is a process for the preparation of N-aryl amine compounds, comprising reacting an amine compound with an arylating compound in the presence of a base and a transition metal catalyst under reaction conditions effective to form an N-aryl amine co... | 08/08/2000 |
| 6072085 | Imine hydrosilylation, uses and reagents related thereto The method of the present invention provides a simple general route to a wide range of secondary amines.... | 06/06/2000 |
| 6034240 | Substituted aminomethylphosphines, coordination complexes of aminomethylphosphines and their synthesis Novel aminomethylphosphine ligands have particular substituents on the central carbon atom. Such ligands form coordination complexes that may be catalysts for the polymerization of monomers or other catalytic induced reactions.... | 03/07/2000 |
| 5929281 | Process for producing heterocyclic aromatic amine or arylamine A heterocyclic aromatic halide or an aryl halide is reacted with an amine compound in the presence of a base to give a heterocyclic aromatic amine or an arylamine, respectively. In this reaction, a catalyst comprising a palladium compound and a tertiary p... | 07/27/1999 |
| 5684132 | Preparation of protected amines or alkylated amino acids The present invention relates to a process for preparing protected amines or amino acids. The invention furthermore relates to the use of tocopheryl radicals or radicals derived therefrom as protective groups for amines and amino acids, and to compounds o... | 11/04/1997 |
| 5576460 | Preparation of arylamines A method of preparing an arylamine compound includes reacting a metal amide comprising a metal selected from the group consisting of tin, boron, zinc, magnesium, indium and silicon, with an aromatic compound comprising an activated substituent in the pres... | 11/19/1996 |
| 5550292 | Benzylamine derivatives A benzylamine derivative or salt thereof having antidepressant and antianxiety activities having the general formula: ##STR1## wherein R1 is a lower alkyl group; R2 is a cycloalkyl group; and R3 is a halogen atom; or salt ... | 08/27/1996 |
| 5536877 | Preparation of arylbenzylamines A process for the preparation of arylbenzylamines by the reaction of arylamines with a benzyl chloride, wherein the reaction is carried out in the presence of both a phase-transfer catalyst and a base selected from the group consisting of the inorganic ba... | 07/16/1996 |
| 5440049 | Process for producing enyne derivatives A compound of the formula: ##STR1## wherein R11 is hydrogen, lower alkyl, haloloweralkyl, lower alkenyl, lower alkynyl or cycloalkyl and R21 is a group selected from the group consisting of: ##STR2## wherein R3 | 08/08/1995 |
| 5436373 | Process for the preparation of N-benzyl-N-organoaminoalkanol N-benzyl-N-organo-substituted aminoalkanol is prepared by reacting benzyl chloride or substituted benzyl chloride with an organo-substituted aminoalkanol in the presence of a molar excess of the starting aminoalkanol and, optionally, water, and in the abs... | 07/25/1995 |
| 5296612 | Process for producing enyne derivatives A process for producing an enyne derivative, and intermediate, which is useful for preparing compounds showing strong inhibiting activities against squalane epoxidase of Eumycetes and strong anti-cholesterol activities. The process comprises reacting a co... | 03/22/1994 |
| 5231183 | Process for producing enyne derivatives A process for producing an enyne derivative, and intermediate, which is useful for preparing compounds showing strong inhibiting activities against squalane.epoxidase of Eumycetes and strong anti-cholesterol activities. The process comprises reacting a co... | 07/27/1993 |
| 5210303 | Process for producing benzylamines A process for producing a benzylamine which comprises reacting a benzyl halide with an aqueous ammonia solution in the presence of an aromatic aldehyde represented by the formula: ##STR1## wherein R represents a hydrogen atom, a halogen atom or a low... | 05/11/1993 |
| 5001251 | Optical resolution of DL-3-acylthio-2-methylpropanoic acid An optically active amine compound and a method for preparing same are provided which compound has the structure ##STR1## in the form of its R-(+) enantiomer or S-(-) enantiomer, wherein R and R1 are independently H, lower alkyl or halogen... | 03/19/1991 |
| 4956055 | Preparation of bidentate ligands A process is disclosed for preparing bidentate ligands of the formula: ##STR1## wherein: each Ar is independently selected from aromatic ring compounds having 6 up to 14 carbon atoms, e.g., phenyl, naphthyl, phenanthryl and anthracenyl; the x bonds a... | 09/11/1990 |
| 4954227 | Preparation of bidentate ligands A process is disclosed for preparing bidentate ligands of the formula: ##STR1## wherein: each AR is independently selected from aromatic ring compounds having 6 up to 14 carbon atoms, e.g., phenyl, naphthyl, phenanthryl and anthracenyl; the x bonds a... | 09/04/1990 |
| 4942261 | Process for preparation of allyl type amine An allyl type amine is prepared by reacting an allyl type alcohol represented by the following formula: ##STR1## wherein R1, R2 and R3 independently stand for a hydrogen atom, an aliphatic hydrocarbon group or alicycl... | 07/17/1990 |
