Class 564/349 - Alkanol group only between the amino nitrogen and the ether oxygen which is bonded directly to the aryl ring or ring system (i.e., aryloxy alkanol amines)

Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which are phenoxy alkanol amines wherein the additional
No. of patents: 167
Last issue date: 05/06/2008

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Number	Title	Issue Date
7368608	1-amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives An 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivative represented by the following formula (1), wherein cycle A may have further 1 to 4 substituents, and said substituent means a substituent selected from the group consisti...	05/06/2008
7338953	Method of treating chronic fatigue syndrome Disclosed herein are methods of treating an individual suffering from, chronic fatigue syndrome. The methods generally include administration of a therapeutic amount of racemic reboxetine, or a pharmaceutically acceptable salt thereof, to the individual. ...	03/04/2008
7335839	Load cell interface for a bed having a stud receiver with a roller axis parallel with an axis of a load cell stud A load cell apparatus has a load cell adapted to couple to a first structure. The load cell comprises a load cell body and a sensor. The sensor provides an output signal indicative of an amount of weight applied to the load cell. A stud extends away from the load ce...	02/26/2008
7276503	Method of treating chronic fatigue syndrome Disclosed herein are methods of treating an individual suffering from, chronic fatigue syndrome. The methods generally include administration of a therapeutic amount of optically pure (S,S) reboxetine, or a pharmaceutically acceptable salt thereof, to the individual...	10/02/2007
7241762	Method of treating peripheral neuropathy Disclosed herein are methods of treating an individual suffering from peripheral neuropathy. The methods generally include administration of a therapeutic amount of racemic reboxetine, or a pharmaceutically acceptable salt thereof, to the individual. ...	07/10/2007
7229782	Antibodies specific to multiple beta blockers and methods for their use The present invention is directed antibodies specific to multiple beta blockers, as well as immunogens used to produce the antibodies and immunoassay kits and methods for using the antibodies. ...	06/12/2007
7227039	RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol The present invention relates to RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol of the formula (1), process for preparation thereof by selective allylation of p-hydroxy phenyl ethanol and use thereof in a preparation of RS betaxolol of formula (2)...	06/05/2007
7129379	3-amino-propoxphenyl derivatives (l) Compounds of formula (Ia) as potent, β1-specific beta blockers with a short duration of action in the systemic circulation, wherein R is 3′,4′-dimethoxyphenyl, R1 is hydrogen, and R2 is selected from methyl, ethyl, propyl, isobu...	10/31/2006
7030160	Propanolaminotetralines, preparation thereof and compositions containing same The invention relates to phenoxypropanolamines, to pharmaceutical compositions containing them, to processes for preparing them, and to the method of use thereof in the treatment of diseases that are improved by beta-3 agonist action. ...	04/18/2006
7019172	Process for preparation of S-(-)-betaxolol and salts thereof The present invention relates to an improved process for preparation of S-(−)-betaxolol salts. More particularly the present invention relates to the preparation of hydrochloride salt of S-(−)-betaxolol of formula (1) ...	03/28/2006
7001615	Sustained release ophthalmic, otic and nasal suspension Sustained release suspension formulations for ophthalmic, otic and nasal administration are disclosed. The formulations comprise a basic active, a cation exchange resin, and a combination of a polymeric suspending agents to provide superior resuspendability. ...	02/21/2006
6989465	S-(−)-1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of S-(−)betaxolo The present invention relates to a novel compound S-(−)-1-{4-[2-(allyloxy)-ethyl] phenoxy}-3-isopropylamino propan-2-ol of formula 1 and to a process for the preparation thereof. More particularly the present invention relates to a process for preparing S-(−)-1-...	01/24/2006
6525222	Process for preparing amines Amines are prepared by reacting aldehydes or ketones at elevated temperature under elevated pressure with nitrogen compounds selected from the group of ammonia, primary and secondary amines, and with hydrogen in the presence of a catalyst, wherein the cat...	02/25/2003
6521667	Calcilytic compounds The present invention features calcilytic compounds. "Calcilytic compounds" refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial e...	02/18/2003
6458955	Process for preparation of pharmaceutically desired enantiomers Improved processes for preparation of high enantiomeric purity compounds center on resolution using simulated moving bed chromatography of a racemic precursor early in the synthesis. Resolution is effected with high enantiomeric purity, and subsequent rea...	10/01/2002
6376711	Method for the preparation of aryl ethers The invention relates to a method for preparing aryl ethers that are useful as antidepressants. The invention also relates to intermediates useful in the method and to methods for preparing such intermediates....	04/23/2002
6355805	댣-adrenergic receptor agonists The present invention is directed to multibinding compounds which are 댣 adrenergic receptor agonists and are therefore useful in the treatment and prevention of metabolic disorders such as obesity, diabetes, and the like....	03/12/2002
6281393	Polyols useful for preparing water blown rigid polyurethane foam Mannich polyols having a viscosity of from 300 to 3,500 cps (0.3 to 3.5 Pa*s) at 25° C. are prepared by admixing a phenol, an alkanolamines, and formaldehyde mixed in molar ratios of from 1:1:1 to 1:2.2:2.2 resulting in an initiator which can be alkoxyla...	08/28/2001
6239313	Process for the solid state synthesis of enantiopure B-aminoalcohols from racemic epoxides The invention relates to a process for the solid state synthesis of enantiopure ଲ-aminoalcohols by preparing inclusion complexes of aryloxyepoxide with cyclodextrin by adding an epoxide in equimolar ratio in an organic solvent to an aqueous solution...	05/29/2001
6127537	Method for preparing 3-amino-1,2-propandiol derivatives A method for the preparation of 3-amino-1,2-propandiol derivatives of the formula (I) ##STR1## by reacting a compound of the formula (II) ##STR2## with RNH2, wherein R and R1 have the same meaning as given in the descr...	10/03/2000
6069177	3-Hydroxy-propanamine derived neuronal reuptake inhibitors 3-Hydroxy-propanamine derivatives and acid salts thereof having chiral centers at the C1 and C2 positions exhibit synaptosomal reuptake inhibition of neurotransmitters, and as such represent a new class of psychotropic agents useful ...	05/30/2000
6057442	Preparation of amines Amines are prepared from primary or secondary alcohols and nitrogen compounds selected from the group of ammonia, primary and secondary amines, at from 80 to 250° C. under pressures from 0.1 to 40 MPa with hydrogen in the presence of a catalyst comprisin...	05/02/2000
6057476	Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers A process for preparation of 3-amino-2-hydroxy-1-propyl ether of the formula ##STR1## wherein R1 is substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heterocyclic ring, R2	05/02/2000
6022894	Method of using calcilytic compounds The present invention features calcilytic compounds. "Calcilytic compounds" refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial e...	02/08/2000
5977410	N-[(fluoroalkoxy) phenoxyalkyl]benzamide compounds, intermediates thereof, process for producing the same, and agricultural and horticultural pesticides Disclosed are A N-[(fluoroalkoxy)phenoxyalkyl]benzamide compound represented by the formula (1): ##STR1## wherein R1 and R3 may be the same or different and represent a hydrogen atom, a halogen atom, a C1-4 alkyl grou...	11/02/1999
5942633	Process for the selective alkylation of betaxolol intermediates The present invention relates to a process for the selective alkylation of intermediates of betaxolol....	08/24/1999
5776985	Fluorinated propranolol and related methods Fluorinated beta blockers, such as propranolol, are presented with amplified antioxidant effects and various levels of beta blocking effects. Mixtures are also presented of fluorinated antioxidant drugs, such as propranolol, with fluorinated antioxidant n...	07/07/1998
5731463	Selective alkylation of an alcohol substituted phenol compound The present invention relates to a process for the selective alkylation of intermediates of betaxolol....	03/24/1998
5684202	Tertiary amines, a process for their preparation and their use as hardening accelerators The present invention relates to novel tertiary amines derived from bisphenoles, diepoxides and aromatic secondary amines, to a process for their preparation and to their use as hardening accelerators for ethylenically unsaturated cold hardenable acrylic ...	11/04/1997
5635534	Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses Compounds of formula (I): ##STR1## (wherein: R0 is hydrogen, methyl or hydroxymethyl; R1 is substituted alkyl; R2 and R3 are each hydrogen, halogen, hydroxy, alkoxy, carboxy, alkoxycarbonyl, alkyl, nitro, h...	06/03/1997
5556864	଱-ω-diarylalkane compounds serotonin-2 receptor agonists Compounds of formula (I): ##STR1## [wherein: R1 is aryl; R2 is hydrogen, alkyl, alkoxy, halogen or cyano; R3 is a group of formula --B--NR4 R5, where R4 and R5 are independe...	09/17/1996
5530127	Preparation of amines A process for the preparatiion of an amine which comprises reacting a primary or secondary alcohol and a nitrogen compound selected from the group consisting of ammonia and primary and secondary amines, at temperatures of from 80° to 250° C. and pressur...	06/25/1996
5504087	1-phenoxy-2-propanol derivatives useful in treating hypertension and glaucoma A hypotensive agent and antiglaucoma agent which comprise a compound represented by the following formula: ##STR1## (wherein R1 is hydrogen, or a lower alkyl or lower alkoxy group; R2 is an isopropylamino, tert-butylamino, ...	04/02/1996
5482964	Substituted phenoxyhydroxypropyl amines as central nervous system agents Substituted phenoxyhydroxy amines and derivatives thereof are described as well as methods for the preparation and pharmaceutical compositions of same, which are central nervous system agents useful in the treatment of neurological disorders including tra...	01/09/1996
5461175	Method for separating enantiomers of aryloxipropanolamine derivatives, and chiral solid-phase chromatography material for use in the method A method for separating enantiomers of a derivative of an aryloxipropanolamine is disclosed, characterized in that the derivative is contacted with a chiral solid-phase chromatography material containing molecular imprints of an optically pure enantiomer ...	10/24/1995
5426227	Enantioselective process for the preparation of leveobunolol The invention relates to a new, industrially advantageous, process for the preparation of the known beta-adrenergic blocking agent, levobunolol, not requiring resolution of racemic bunolol, based on the enantioselective synthesis of an oxiranic intermedia...	06/20/1995
5391476	Non-ionic surface active compounds Water-soluble, non-ionic surface active compounds are provided having the formula ##STR1## wherein R1 and R2 are each independently hydrogen or an alkyl group having from 1 to 4 carbon atoms; X is a hydrophobic substituted or un...	02/21/1995
5391735	Process for the preparation of 3-substituted derivatives of 1-amino-2-hydroxy-propane The present invention relates to a new process for the preparation of 3-substituted derivatives of 1-amino-2-hydroxy-propane in the form of single diastereoisomers, to certain of these diastereoisomers, and to compounds which are intermediates in the new ...	02/21/1995
5382689	Process for preparation of bevantolol hydrochloride Disclosed is a new process for preparing bevantolol hydrochloride suitable for industrial production in which bevantolol hydrochloride can be obtained in a high yield and HVA of an expensive material can be recovered. The process for the preparation of be...	01/17/1995
5347050	3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them The compounds of formula I, ##STR1## wherein the substituents have various significances, and physiologically acceptable hydrolyzable derivatives thereof having the hydroxy group in the 2 position of the 3-aminopropoxy side chain in esterified form, ...	09/13/1994

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Class 564/349 - Alkanol group only between the amino nitrogen and the ether oxygen which is bonded directly to the aryl ring or ring system (i.e., aryloxy alkanol amines)