Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 7385064 | Catalysts for use in enantioselective synthesis Disclosed are compounds having the following formula: in which Z11 is selected from a substituted or unsubstituted saturated adamantyl or other polycyclic group and a substituted or unsubstituted branched acyclic... | 06/10/2008 |
| 7351389 | Aminocarboxylate ligands having substituted aromatic amide moieties Novel metal-chelate complexes comprising aminocarboxylate ligands including substituted aromatic amide moieties, such as those having the formula wherein R13, A1, R1 and R2 are as... | 04/01/2008 |
| 7297820 | Stilbene derivatives and their use for binding and imaging amyloid plaques This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregat... | 11/20/2007 |
| 7179926 | Aryloxyalkylamine NK-1/SSRI inhibitors The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts and solvates, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both. | 02/20/2007 |
| 7109343 | Metal catalysts and methods for making and using same Compounds having the formula: are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessa... | 09/19/2006 |
| 7045649 | C2-substituted idan-1-ols and their derivatives, processes for their preparation and their use as pharmaceuticals Embodiments of the invention relate to C2-substituted indan-1-ols and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention may include compounds of formula I | 05/16/2006 |
| 7015208 | C2-substituted indan-1-ols and their derivatives, processes for their preparation and their use as pharmaceuticals Embodiments of the invention relate to C2-substituted indan-1-ols and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention may include compounds of formula I | 03/21/2006 |
| 6958419 | Alkynyl S,N-acetal derivative and method of producing the same An alkynyl S,N-acetal derivative of the present invention is represented by the following structural formula: In the structural formula, R1 represents a hydrogen atom, an alkyl group, an aryl group, an alken... | 10/25/2005 |
| 6919380 | Derivatives of C2-substituted indan-1-ol systems for the prophylaxis or treatment of obesity Derivatives of C2-substituted indan-1-ol compounds of formula I: its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of obesity are disclosed herein. Co... | 07/19/2005 |
| 6812256 | Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity Polysubstituted indan-1-ol compounds of formula I, its physiologically acceptable salts and physiologically functional derivatives are disclosed Compositions comprising the same, methods of preparation and methods for ... | 11/02/2004 |
| 6762326 | C2-substituted idan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals Embodiments of the invention relate to C2-substituted indan-1-ones and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention include compounds of formula I | 07/13/2004 |
| 6686397 | Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity Polysubstituted indan-1-ol compounds of formula I, its physiologically acceptable salts and physiologically functional derivatives are disclosed: ##STR1## Compositions comprising the same, methods of preparation and methods for the prophylaxis or treatmen... | 02/03/2004 |
| 6670401 | Polysubstituted indan-1-ol compounds, and methods for their preparation and use Polysubstituted indan-1-ol compounds, methods for their preparation; and methods for their use are disclosed herein. In particular, the invention relates to polysubstituted indan-1-ol compounds of the formula I ##STR1## and their physiologically acceptabl... | 12/30/2003 |
| 6667345 | Derivatives of C2-substituted indan-1-ol systems for the prophylaxis or treatment of obesity Derivatives of C2-substituted indan-1-ol compounds of the formula I: ##STR1## its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of obesity are disclosed herein. Compositions comprising th... | 12/23/2003 |
| 6410746 | Metal cataltsts and methods for making and using same Compounds having the formula: ##STR1## are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessary to complete a 3-12 membered het... | 06/25/2002 |
| 6281379 | Process for producing norstatin derivatives This invention to provide a process for producing an optically active threo-phenylnorstatin derivative which does not require a toxic cyanating agent or a costly reagent, or a complicated procedure, and can be practiced on a commercial scale. This inventi... | 08/28/2001 |
| 6255496 | Trifluoromethyl ketone analogs as selective cPLA2 inhibitors Selective inhibitors of the cPLA2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula ##STR1##... | 07/03/2001 |
| 6150558 | Bis-o-amino(thio)phenols, and their preparation The invention relates to novel bis-o-aminophenols, and bis-o-aminothiophenols of the following structure: ##STR1## where A1 to A6 are--independently of one another--H, F, CH3, CF3, OCH3, OCF... | 11/21/2000 |
| 6022906 | -aminoacetophenone photoinitiators Compounds of the formulae I, II, III and IV ##STR1## wherein Ar for example is a phenyl, biphenyl or benzoylphenyl group, which is unsubstituted or substituted; Ar1, for example, has the same meanings as Ar; Ar2 is inter alia ph... | 02/08/2000 |
| 5952316 | 2-amino-1,3-propanediol compound and immunosuppressant 2-Amino-1,3-propanediol compounds of the formula (I) ##STR1## wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R2, R3 | 09/14/1999 |
| 5925332 | Radioimaging and radiochemotherapy phenolic thioether amines and acyl derivatives thereof for use in diagnosing and treating pigmentation disorders Compounds useful in radioimaging and radiochemotherapy as it particularly relates to the treatment and location of malignant melanomas and other pigmenting disorders, as well as novel acyl derivatives of phenolic thioester amines and their use in composit... | 07/20/1999 |
| 5789448 | Benzoylethylene derivative Disclosed is a benzoylethylene derivative represented by the following formula (I) or a salt thereof. ##STR1## R1 to R5 : a hydrogen atom, --OR9 (R9 : a hydrogen atom, a C1 -C5 alkyl g... | 08/04/1998 |
| 5756068 | Methods of radioimaging and radiochemotherapy using phenolic thioeter amines and acyl derivatives thereof Compounds useful in radioimaging and radiochemotherapy as it particularly relates to the treatment and location of malignant melanomas and other pigmenting disorders, as well as novel acyl derivatives of phenolic thioester amines and their use in composit... | 05/26/1998 |
| 5741821 | Use of natural products and related synthetic compounds for the treatment of cardiovascular disease Use of a compound of formula (I), wherein Ar is an aromatic ring system comprising one or more optionally substituted phenyl rings optionally linked to or fused with one or more other optionally substituted phenyl rings or one or more 5 or 6-membered, opt... | 04/21/1998 |
| 5719176 | 2-amino-1,3-propanediol compound and immunosuppressant A 2-amino-1,3-propanediol compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, and an immunosuppressant containing the same as the active ingredient. In said formula R represents optionally substituted linear or branc... | 02/17/1998 |
| 5674909 | Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system Compounds of formula ##STR1## wherein R, R', R", R1, R2, R3, R4, R5, R6, X, Y, m, n and p have the meanings reported in the description; and their pharmaceutically acceptable salts are desc... | 10/07/1997 |
| 5639887 | MDR reversal agents Compounds of the general formula: ##STR1## wherein R1, R2, R3, R4 and R5 are herein described, A is a straight or branched (C2 -C12)alkyl or a phenyl moiety and B is a moiet... | 06/17/1997 |
| 5612381 | 1,2-ethanediol derivative and salt thereof process for producing the same, and cerebral function-improving agent comprising the same This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebro... | 03/18/1997 |
| 5604229 | 2-amino-1,3-propanediol compound and immunosuppressant 2-Amino-1,3-propanediol compounds of the formula (I) ##STR1## wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R2, R3 | 02/18/1997 |
| 5426226 | Intermediates for making ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor. An intermediate for preparing the novel compounds have the following formula: ... | 06/20/1995 |
| 5371247 | Preparation of substituted ethenes A potassium salt useful in the production of certain N-substituted alkyl or arylalkyl thionitroethenamines is produced by the reaction of the dipotassium salt of a 2-nitrodithio aliphatic acid such as 2-nitrodithio acetic acid with branched chain primary ... | 12/06/1994 |
| 5349108 | 5-substituted-2,4-diphenylpyrimidine derivatives, their production and use A compound of the formula (VIII): ##STR1## wherein R1 represents a halo-(C1 to C6)-alkoxy group at the ortho or meta position; and W2 represents a methanesulfonyl group, a methylthio group or ##STR2## ... | 09/20/1994 |
| 5302757 | Ultraviolet light sensitive onium salts A composition of matter including an onium salt and a method of forming images. The onium salt has a chromophore which absorbs ultraviolet radiation, an S, Se, As, N or P atom which is free of substituents exhibiting a higher energy occupied molecular orb... | 04/12/1994 |
| 5298483 | New matter of composition and method for using the same as plant bioregulators The present invention is directed to a new matter of composition in the form of chemical compounds and to a method for enhancing plant growth and the properties exhibited by plants treated with the compounds in accordance with this method. In particular, ... | 03/29/1994 |
| 5276190 | Method for the preparation of an alcohol The invention relates to a method for the preparation of an ,-disubstituted -amino alcohol from the corresponding amide with the aid of sodium in the presence of an alcohol as solvent. The conversion of amino acid amide to amino alcoh... | 01/04/1994 |
| 5212173 | Alkylaminoalkylamine and ether compounds, processes and intermediates for their preparation, and medicaments containing them Pharmacologically active compounds corresponding to the formula I ##STR1## in which n represents 2-5, m represents 2-6, R1 denotes hydrogen or lower alkyl, R2 represents an OR4 group in which R4 denotes lower alkyl ... | 05/18/1993 |
| 5198134 | Substituted naphthalenediamine stabilizers N-Allyl and N-methylene-thio substituted naphthalene-1,8- or -1,5-diamine compounds are very effective antioxidant stabilizers for organic material subject to oxidative or thermal degradation, particularly for lubricant compositions.... | 03/30/1993 |
| 5073173 | Dye couplers The present invention concerns the aminophenols (I) as novel couplers ##STR1## wherein R1 and R2 may be the same or different and are hydrogen, alkyl and hydroxyalkyl of from 1 to about 6 carbons in the alkyl moiety, or R1 | 12/17/1991 |
| 5023378 | Amine derivatives The invention provides compounds of the general formula (I) ##STR1## and physiologically acceptable acid addition salts, metabolically labile esters and solvates thereof in which R1 represents a halogen atom or a methyl, ethyl, n-propyl or n-bu... | 06/11/1991 |
| 5021429 | Pharmacologically active aminoalkylphenyl compounds and their use Compounds of the general formula: ##STR1## and physiologically acceptable salts, and hydrates, N-oxides and bioprecursors of such compounds and such salts in which R1 and R2, which may be the same or different, represent hydrogen ... | 06/04/1991 |