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| Number | Title | Issue Date |
| 7763751 | Hydroxylamine derivatives This invention is related to hydroxylamino derivatives of the general formula (I) wherein n is 0, 1 or 2; R1 and R2, independently of each other, are H, OH or OCH3; R3 is H or CH3; R4 is H, C1 | 07/27/2010 |
| 7745663 | 5-Substituted-2-phenylamino benzamides as MEK inhibitors An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the prese... | 06/29/2010 |
| 7663001 | Preparation of isoxazolin-3-ylacylbenzene A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C | 02/16/2010 |
| 7491846 | Process for producing hydroxylamine It is an object of the present invention to provide a process for producing a hydroxylamine by reacting a salt of hydroxylamine with an alkali compound, where the yield reduction due to formation of a complex between the produced hydroxylamine and a salt produced as... | 02/17/2009 |
| 7425652 | Preparation of alkanolamines Alkanolamine compositions are disclosed. The composition comprises an alkanolamine and hydroxylamine or hydrazine. Preferred alkanolamine includes diethanolamine, triethanolamine, and mixtures thereof. The composition of the invention has significantly reduced disco... | 09/16/2008 |
| 7417168 | Method for preparing hydroxylamine A method for preparing hydroxylamine is provided that includes the steps of (i) pretreating an acidic buffer solution; and (ii) reducing nitrate ions in the acidic buffer solution with hydrogen to give hydroxylamine in the presence of catalysts, wherein the pretreat... | 08/26/2008 |
| 7399885 | Method for preparing hydroxylamine A method for preparing hydroxylamine, comprising the steps of: (i) pretreating the acidic buffer solution with the compounds having a functional group represented by formula (I), thereby removing metal impurities from the acidic buffer solution; and (ii) reducing ni... | 07/15/2008 |
| 7396959 | Process for preparing symmetrical and unsymmetrical N,N-dihydrocarbylhydroxylamines A process for preparing N,N-dihydrocarbylhydroxylamines of the general formula (I) where R1, R2, R3 and R4 are selected independently from among hydrogen, aliphatic, cycloaliphati... | 07/08/2008 |
| 7381843 | Method for preparing hydroxylamine A method for preparing hydroxylamine by reducing nitric acid or its salt with hydrogen gas in an aqueous medium in the presence of a catalyst, wherein reduction of nitric acid or its salt is performed in a reactor comprising a reaction section, a cooler disposed at ... | 06/03/2008 |
| 7361755 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines This invention pertains to a novel process for preparing sterically hindered N-substituted alkyloxyamines from alkenes by the transition-metal-catalyzed reaction of a intermediate alkylborane with a sterically hindered nitroxyl radical. ... | 04/22/2008 |
| 7323596 | Antimicrobial agents Compounds of formula (I) and (IA) have antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH(═O) or of formula C(═O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except whe... | 01/29/2008 |
| 7309802 | Preparation of isoxazolin-3-ylacylbenzene A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, ... | 12/18/2007 |
| 7297819 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization The present invention relates to open chain alkoxyamine compounds, a polymerizable composition comprising a) at least one ethylenically unsaturated monomer and b) at least one open chain alkoxyamine compound. Further aspects of the present invention are a process fo... | 11/20/2007 |
| 7291669 | Stabilized polyolefin compositions Polyolefin compositions comprising a particular hindered phenolic antioxidant selected from the group consisting of tris(3,5-di-tert-butyl-4-hydroxybenzyl)isocyanurate, 1,3,5-tris-(3,5-di -tert-butyl-4-hydroxybenzyl)-2,4,6-trimethylbenzene and the calcium salt of th... | 11/06/2007 |
| 7279601 | Optically active α-aminooxyketone derivatives and process for production thereof The corresponding α-aminooxy ketone is manufactured with a high yield and a high enantioselectivity. A manufacturing method for an optically active α-aminooxy ketone derivative expressed by formula (1), wherein a ketone expressed by formula (2) is caused to react ... | 10/09/2007 |
| 7226964 | Composition comprising a nitroxide, a promoter and optionally a free-radical initiator The present invention relates to the prevention of scorching before crosslinking of a thermoplastic and/or elastomeric composition with peroxides or azo compounds. This is achieved by using a nitroxide in combination with at least one crosslinking promoter (promoter... | 06/05/2007 |
| 7214825 | O-(3-chloropropenyl) hydroxylamine free base An O-substituted hydroxylamine having the following general formula: R1—CHX—O—NH2 wherein X is hydrogen or an alkyl; and R1 is an unsubstituted or substituted phenyl, thienyl, furanyl, pyrrolyl or —CR | 05/08/2007 |
| 7186273 | Treatment of textiles with fluorinated polyethers A polymer adapted for the Shrink resist treatment of textile materials imparting water, stain and/or oil repellency. The polymer includes a fluorinated polyether. ... | 03/06/2007 |
| 7176242 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as i... | 02/13/2007 |
| 7084196 | Flame retardant compositions Polymeric substrates, for example polyolefins such as polypropylene, can be made flame retardant by the incorporation therein of a synergistic mixture of (i.) at least one compound selected from the group consisting of nitroxyl stabilizers, hydroxylamine stabilizers... | 08/01/2006 |
| 7049308 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less th... | 05/23/2006 |
| 7022390 | Polyester and polyamide compositions of low residual aldehyde content A mixture of a polyester, such as poly(ethylene terephthalate) PET, or a polyamide, and a suitable stabilizer selected from the group consisting of hydroxylamine stabilizers, substituted hydroxylamine stabilizers, nitrone stabilizers and amine oxide stabilizers, whe... | 04/04/2006 |
| 6998419 | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same Disclosed are 3,4,5-trisubstituted aryl nitrone compoundsd and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have formula (I); where R1–R4 are as defined in the specification. The discl... | 02/14/2006 |
| 6974853 | Acrylate contact adhesive materials having tight molecular weight distribution An initiator system for radical polymerization, which comprises a combination of compounds of the formulae: ... | 12/13/2005 |
| 6919481 | Alkoxyamines containing a vinyl group, their applications and methods of their production Alkoxyamines containing a vinyl group as represented by the following general formula (1) are produced in a method which comprises a process of heating divinyl benzene, nitroxide compound and organic peroxide up to a temperature at which the organic peroxide decompo... | 07/19/2005 |
| 6908650 | Polyester and polyamide compositions of low residual aldehyde content A mixture of a polyester, such as poly(ethylene terephthalate) PET, or a polyamide, and a suitable stabilizer selected from the group consisting of hydroxylamine stabilizers, substituted hydroxylamine stabilizers, nitrone stabilizers and amine oxide stabilizers, whe... | 06/21/2005 |
| 6906104 | Aminediols for the treatment of Alzheimer's disease The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treat... | 06/14/2005 |
| 6902695 | Stabilizer combination for the rotomolding process A process for the production of polyolefin hollow articles comprises charging the polyolefin with a stabilizer combination comprising (a) at least one compound from the group of the organic phosphites or phosphonites, (b) one or more compounds selected from the grou... | 06/07/2005 |
| 6875831 | Mono and multifunctional alkoxyamines for the preparation of functionalized macromers The invention pertains to a compound of formula (I), (II) or (III) wherein R1 and R2 are independently of each other hydrogen, C1-C18alkyl, C3-C18alkeny... | 04/05/2005 |
| 6841703 | Open chain alkoxyamine compounds and their use as polymerization regulators The invention relates to a compound of formula Ia, Ib or Ic The open chain alkoxyamine compounds are useful for the polymerization of ethylenically unsaturated monomers. The compounds of the present invention provide p... | 01/11/2005 |
| 6841668 | Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines Sterically hindered N-substituted aryloxyamines are prepared by the Keggin polyoxometalate or the transition metal substituted polyoxometalate (TMS-POM) catalyzed decomposition of diazonium salts in the presence of a sterically hindered nitoxyl radical. These compou... | 01/11/2005 |
| 6828460 | Resorcinol derivatives The present invention relates to the use of certain resorcinol derivatives as skin lightening agents. ... | 12/07/2004 |
| 6815425 | Pharmaceutical composition containing pGLU-GLU-PRO-NH2 and method for treating diseases and injuries to the brain, spinal cord and retina using same A nueroprotectant composition wherein the active ingredient is pGLU-GLU-PRO-NH2 or a combination of pGLU-GLU-PRO-NH2 (EEP) and N-tert-Butyl-α-(2-sulfophenyl)nitrone (SPBN) or other nitrone. A method of treating and preventing diseases and inju... | 11/09/2004 |
| 6787570 | Substituted N-cycloalkyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted N-Alkyl/Alkenyl/Cycloalkyl/Heterocycyl N-Aryl/Heteroaryl tertiary-Heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and metho... | 09/07/2004 |
| 6716878 | Antimicrobial agents Compounds of formula (I) are antibacterial agents: wherein Z represents a radical of formula —N(OH)CH(═O) or of formula —C(═O)NH(OH), and R1-R4 are as defined in the specification. A method ... | 04/06/2004 |
| 6717012 | Antioxidant nitroxides and nitrones as therapeutic agents The invention provides novel adamantane compounds having one of the following formulas: wherein: R1 and R3 are H, OH, alkyl, cycloalkyl, amino or aryl, and can be the same or different; | 04/06/2004 |
| 6700007 | Method for preparing alkoxyamines from nitroxides A process for preparing alkoxyamines in a biphasic medium comprises mixing an ionic liquid, an organic solvent, a metal salt, a ligand for the metal, a halocarbon compound ZX and a nitroxide, keeping the reaction medium stirring at a temperature of betwee... | 03/02/2004 |
| 6696472 | Substituted N-phenoxy-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 02/24/2004 |
| 6686424 | Preparation of functionalized alkoxyamine initiator and its use A one-pot process for the preparation of functional alkoxyamines of the general formula (I), ##STR1## is disclosed. The process entails (1) reacting an oxidizing agent with a sterically hindered secondary amine to produce an aqueous phase and a nitro... | 02/03/2004 |
| 6677379 | Substituted N,N-disubstituted diamino compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroary tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating ... | 01/13/2004 |
