Class 564/299 - Benzene ring containing

Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the amine oxide contains a benzene ring.
No. of patents: 40
Last issue date: 05/08/2012

Number	Title	Issue Date
8173843	Amphiphilic derivatives of α-C-phenyl--butylnitrone Compounds derived from α-C-phenyl-N-tert-butylnitrone, a process for the preparation thereof and use thereof for the preparation of medicaments for use in preventing or treating oxidative stress-related diseases. ...	05/08/2012
7696383	N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs Embodiments of the invention relate to a compound of formula (1), or a tautomer, stereoisomer, hydrate, or solvate thereof, wherein R1 is H or CH3. Other embodiments of the invention relate to a pharma...	04/13/2010
7326730	Aminoadamantane derivatives as therapeutic agents The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and composi...	02/05/2008
6753429	1,4-disubstituted benzenes as insecticides Compounds of formula I: wherein A, B, D, and R are as defined herein and their agriculturally acceptable salts are disclosed as effective insecticides. In addition, compositions comprising an insecticidally effective amo...	06/22/2004
6717012	Antioxidant nitroxides and nitrones as therapeutic agents The invention provides novel adamantane compounds having one of the following formulas: wherein: R1 and R3 are H, OH, alkyl, cycloalkyl, amino or aryl, and can be the same or different;	04/06/2004
6689911	Process An integrated process for preparing ଱-(2,4-disulfophenyl)-N-tert-butylnitrone and its salts is disclosed in which N-tert-butylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutrali...	02/10/2004
6512136	Substituted 2-phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them New compounds of formula I are described ##STR1## The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders, where a reduction in the O-methylation of catecholamines may be o...	01/28/2003
6417401	Ether diamines amine oxides The present invention is related to a series of derivatives of novel ether diamine compounds prepared by the cyanobutylation reaction of an alcohol having 3 to 22 carbon atoms with 2-pentenenitrile to form a branched alkyl ether nitrile. The etheraminonit...	07/09/2002
6291702	Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping...	09/18/2001
6197825	Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping...	03/06/2001
6002002	Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions The present invention provides novel hydroxylamine derivatives represented by the general formula: wherein: X is O, --NH, or a group of formula NR', wherein R and R' are independently selected from alkyl, cycloalkyl, phenylalkyl, phenyl optionally substit...	12/14/1999
5892117	Preparation and uses of N-methylnitrone Oxidation of secondary amines with hydrogen peroxide and sodium tungstate is reported to give good yields of nitrones. However, when using dimethylamine in this manner, a considerable amount of N,N-dimethylformamide was produced as a co-product. To more s...	04/06/1999
5837717	Hydroxamic acid anesthetic compounds A compound of the following formula: ##STR1## and its pharmaceutically acceptable salt thereof, wherein R1 and R2 are independently hydrogen, C1-4 alkyl, C3-7 cycloalkyl, C2-4 alkenyl, C1-4	11/17/1998
5650425	Permanently ionic derivatives of steroid hormones and their antagonists The present disclosure relates to compounds of the general formulae: ##STR1## wherein DRUG is a steroid agonist or antagonist, a mixed agonist-antagonist, or a partial agonist, and to the use of such compounds as anti-inflammatory and anti-tumor agen...	07/22/1997
5639880	Preparation of amine oxides A process for preparing amine oxides of the general formula I ##STR1## where R1, R2 and R3 are each C1 -C30 -alkyl, C3 -C12 -cycloalkyl, C1 -C30 -hydroxyalk...	06/17/1997
5498791	Nitrosamine and nitrite inhibition A synergistic mixture of a carbonate and/or bicarbonate with a phosphonate, especially an organoamino methylene phosphonate or an N-oxide thereof, inhibits or reduces nitrosamine contamination during preparation, storage and/or heating of products which a...	03/12/1996
5461078	Anti-cancer compounds Compounds of formula (I) ##STR1## in which R1 is CH.dbd.CHR, CH.dbd.NNHR, CH.dbd.N--A--N(O)R'R" or CH2 --NH--A--N(O)R'R" and R2 is separately selected from hydrogen, CH.dbd.CHR, CH.dbd.NNHR, CH.dbd.N--A--(O)R'R" and C...	10/24/1995
5223541	Tramadol N-oxide material, enantiomers and compositions thereof, and their use This invention relates to a tramadol N-oxide material, enantiomers and compositions thereof and their use. The tramadol N-oxide material and compositions thereof are pharmacologically useful in treating pain, diarrhea and tussive conditions. The tramadol ...	06/29/1993
5164121	Pourable composition containing an amine oxide -polyethylene glycol mixture A pourable amine oxide composition which is suitable for use in detergent compositions is obtained by reacting a tert-amine with aqueous hydrogen peroxide in a normally liquid polyethylene glycol as the sole organic solvent. When the composition has a low...	11/17/1992
5162408	N-alkenyl substituted amine-N-oxide stabilizers N-Alkenyl substituted hydroxylamines of formula I ##STR1## where R1 and R2 are independently hydrogen, alkyl, aryl or phenylalkyl, and R3 to R7 are independently hydrogen, alkyl or substituted alkyl are ver...	11/10/1992
5087752	Synthesis of nitroxides using dioxiranes The subject invention relates to a method of synthesizing nitroxides from secondary amines. This method uses a suitable dioxirane compound such as dimethyldioxirane (DMD), which is relatively stable and simple to synthesize, as the oxidizing agent. A quan...	02/11/1992
5082938	Organic materials containing poly(oxyalkylene) moieties having enhanced functionality and their preparation Enhanced branched chain hydroxyl compounds are provided of formula Y--(Z)1-6 wherein Y is the residue of a nucleophile devoid of conjugated divalent linking moieties, and each Z is a poly(oxyalkylene) moiety having a molecular weight of from about 2...	01/21/1992
5082940	Process for the production of oxides of aromatic tertiary amines Aromatic tertiary amines are oxidized by means of hydrogen peroxide in an inert solvent medium in the presence of a catalyst selected from metal selenium and compounds of selenium. The process is applied to the preparation of oxides of heterocyclic aromat...	01/21/1992
5081300	N-alkenyl substituted amine-N-oxide stabilizers N-substituted hydroxylamines of formula I ##STR1## where R1 and R2 are independently hydrogen, alkyl, alkenyl, aryl or phenylalkyl, and R3 to R7 are independently hydrogen, alkyl or substituted alkyl are ve...	01/14/1992
5021429	Pharmacologically active aminoalkylphenyl compounds and their use Compounds of the general formula: ##STR1## and physiologically acceptable salts, and hydrates, N-oxides and bioprecursors of such compounds and such salts in which R1 and R2, which may be the same or different, represent hydrogen ...	06/04/1991
4992589	Substituted phenyl hydroxyethyl sulfones, and process for their preparation Compounds of the formula (1) ##STR1## in which X denotes a sulfur atom or the group ##STR2## in which R denotes a hydrogen atom, an alkylene-C1 -C4 -alkoxy-C1 -C6 - or alkyl-C1 -C6	02/12/1991
4960934	Amine oxide process The reaction of aqueous hydrogen peroxide with tert-amines to yield tert-amine oxides is catalyzed by the addition of a promoter amount of ammonium carbonate, ammonium bicarbonate or ammonium carbamate or mixtures thereof....	10/02/1990
4942260	Amine oxide process with CO₂ and aluminum Amine oxides which have low levels of nitrosamines or are substantially-free of nitrosamines are made by reacting tert-amines with hydrogen peroxide in the presence of carbon dioxide and aluminum metal....	07/17/1990
4696949	Novel tri-phenyl alkane and alkene derivatives and their preparation and use The invention provides novel compounds of the formula: ##STR1## wherein n is 0 to 4, R1 and R2, which can be the same or different are H, OH, alkoxy of 1 to 4 carbon atoms, benzyloxy or methoxymethoxy; R3 is H, OH, ha...	09/29/1987
4677049	Spin castable photobleachable layer forming compositions Spin castable mixtures having aryl nitrones are provided which are useful in making photobleachable layers for use in contrast enhanced photolithography....	06/30/1987
4661433	Storage stable aryl nitrone compositions Aryl nitrones, of the type used in contrast enhancement photolithography techniques, are stabilized by adding thereto a drying agent such as molecular sieve, silica gel or an alkylalkoxysilane. The resulting compositions are substantially storage stable....	04/28/1987
4399077	Certain polyoxy perfluorinated surface active oligomers Perfluorinated surface-active block or random oligomers of the formula ##STR1## where R denotes a C2 -C18 -hydrocarbon or- hydrofluorocarbon radical, Y denotes a C6 -C13 -fluorocarbon or- hydrofluorocarbon radic...	08/16/1983
4347381	Method of treating long chain alkyl amines or products derived therefrom The pink color content often produced in products such as amine salts, amine oxides, betaines, quaternary ammonium compounds or other compounds derived from long chain alkyl amines is eliminated by treating the products with trace amounts of a bleaching a...	08/31/1982
4275236	Tertiary di-(ଲ-hydroxy organo) amine oxides and their preparation Disclosed are tertiary amine oxides which comprise an amine oxide nucleus substituted with an organic group and with two hydroxy groups which have carbon atoms in at least the ଱, ଲ and γ positions, a hydroxyl group on the ଲ-carbon atom,...	06/23/1981
4264776	Production of secondary amines Tertiary amines such as alkyl or benzyl amines are catalytically oxidized by oxygen over an activated carbon catalyst to selectively produce secondary amines....	04/28/1981
4172093	Pharmacodynamically active indan derivatives The present invention relates to new pharmacodynamically active compounds of the general structure ##STR1## as well as the corresponding amine oxides, quarternary ammonium compounds and salts with physiologically acceptable acids. In formula I R...	10/23/1979
4169156	N-(2-aminocycloheptyl)alkanoylanilides N-(2-aminocycloheptyl)N-alkanoylanilides and their 2-N-oxides of the formula ##STR1## e.g., trans-3,4-dichloro-N-[2-(allylamino)cycloheptyl]propionanilide, and their pharmacologically acceptable salts, have been found to possess potent Central N...	09/25/1979
4153629	9,10-Dihydro-9,10-methanoanthracene N-oxide 9,10-Dihydro-9,10-methanoanthracene N-oxide derivatives represented by the formula: ##STR1## wherein A represents a straight or branched C1 -C6 alkylene; R1 and R2 each represents C1 -C4	05/08/1979
3957872	Benzobicycloalkane amine N-oxides and the salts thereof Benzobicycloalkane amines, their pharmacologically acceptable addition salts, intermediates therefore the processes for their preparation and use. The compounds of the invention exert analgesic and antiinflammatory activity....	05/18/1976
3952017	Tricyclic compounds 1-Methyl(or acetyl)-5H-dibenzo[a,d]cycloheptenes and 1-methyl(or acetyl)-10,11-dihydro-5H-dibenzo[a,d]cycloheptenes bearing a basic side chain at the 5-position, such as a 3-mono- or dimethylaminopropylidene, a 3-mono- or dimethylaminopropyl or a 3-dimeth...	04/20/1976

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Class 564/299 - Benzene ring containing