William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Number | Title | Issue Date |
| 7915450 | Transfection reagents Disclosed are cationic lipid compounds and compositions of lipid aggregates for delivery of macromolecules and other compounds into cells. The compounds can be used alone or in combination with other compounds lo prepare liposomes and other lipid aggregates suitable... | 03/29/2011 |
| 7868208 | Polyquaternary alkyl polymers The present invention relates to a novel class of polymeric compounds having specific highly crosslinked cationic or amphoteric structure. These products are produced without free radical monomers ands are based upon an alkyl diamine which has been reacted to produc... | 01/11/2011 |
| 7851653 | Method of creating a solvent-free polymeric silicon-containing quaternary ammonium antimicrobial agent having superior sustained antimicrobial properties An antimicrobial polymer is disclosed containing silicon-containing quaternary ammonium groups, the polymer including in its structure repeating units of Formula II: R3N+R0nSiX′4-nY− â... | 12/14/2010 |
| 7601872 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting of N, O and S; L is any ... | 10/13/2009 |
| 7598421 | Materials for the delivery of biologically-active material to cells The invention provides a lipid of general formula (I) or (II): wherein X1, X2 and R1 to R5 are as defined herein. Such lipids are used to form complexes with a biologically-active... | 10/06/2009 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7300545 | Water-soluble polymer dispersion, process for producing the same and method of use therefor A water-soluble polymer dispersion, process for producing the same and a method of use therefor. In particular, the water-soluble polymer dispersion is one comprising water-soluble polymer fine particles of 100 μm or less diameter having at least one ionic property... | 11/27/2007 |
| 7214806 | Synthetic multiple quaternary ammonium salts This invention pertains to novel multiple quaternary ammonium salts and their derivatives represented by the formula: wherein each R1, R′1, R2, R′2, R3, ... | 05/08/2007 |
| 7208605 | Functionalized ionic liquids, and methods of use thereof One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze... | 04/24/2007 |
| 7193111 | Dimer poly-quaternary compounds The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid reacted with an dimethyl amino propyl amine to make an amido amine, which is subsequently reacted to make a polymeric quaternary compound.... | 03/20/2007 |
| 7189865 | Thiomolybdate analogues and uses thereof The current invention provides novel thiomolybdate derivatives, methods of making novel thiomolybdate derivatives, pharmaceutical compositions of novel thiomolybdate derivatives, methods of using novel thiomolybdate derivatives to treat diseases associated with aber... | 03/13/2007 |
| 7189874 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting of N, O and S... | 03/13/2007 |
| 7166745 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/23/2007 |
| 7026512 | Tertiary alkanolamines containing surface active alkyl groups The present invention relates to novel tertiary alkanolamines useful as catalysts for preparing polyurethane foams and as additives to reduce the dynamic surface tension of aqueous solutions. The tertiary alkanolamines may be represented by formula (I): ... | 04/11/2006 |
| 7002042 | Cationic liposomes for gene transfer The present invention relates to synthetic cationic lipids, liposome formulations and the use of such compounds to introduce functional bioactive agents into cultured cells. ... | 02/21/2006 |
| 6960690 | Process of making a compound by forming a polymer from a template drug A method of forming polymers in the presence of nucleic acid using template polymerization. Also, a method of having the polymerization occur in heterophase systems. These methods can be used for the delivery of nucleic acids, for condensing the nucleic acid, for fo... | 11/01/2005 |
| 6914041 | Laundry detergent compositions comprising zwitterionic polyamines and mid-chain branched surfactants The present invention relates to laundry detergent compositions which provide enhanced hydrophilic soil cleaning benefits comprising a zwitterionic polyamine, a surfactant system comprising a mid-chain branched surfactant, and carrier and other adjunct ingredients. | 07/05/2005 |
| 6903059 | Laundry detergent compositions comprising polyamines and mid-chain branched surfactants The present invention relates to detergent compositions comprising a polyamine with defined end capping units and a mid-chain branched surfactant and also optionally containing a bleach agent, aluminosilicate, silicate, and/or detersive enzyme. ... | 06/07/2005 |
| 6900313 | Chiral ionic liquids The invention relates to chiral ionic liquids of the general formula [A]n+[Y]n−, whereby n=1 or 2, the anion [Y]n− is the anion of an organic or inorganic proton acid and the cation [A]+ ... | 05/31/2005 |
| 6812198 | Laundry detergent compositions comprising hydrophobically modified polyamines The present invention relates to hydrophobically modified polyamines and laundry detergent compositions which comprise said polyamines, said compositions comprising: A) from about 0.01%, preferably from about 0.1%, more preferably ... | 11/02/2004 |
| 6716882 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transfor... | 04/06/2004 |
| 6706922 | Process of making a compound by forming a polymer from a template drug A method of forming polymers in the presence of nucleic acid using template polymerization. Also, a method of having the polymerization occur in heterophase systems. These methods can be used for the delivery of nucleic acids, for condensing the nucleic acid, for fo... | 03/16/2004 |
| 6673890 | Zwitterionic polyamines and process for their production A zwitterionic polyamine comprising a linear or branched hydrophobic polyamine backbone having 2 to 10 tertiary amino nitrogen atoms and a spacer between two tertiary nitrogen atoms wherein the spacer is, for example selected from C8 -C16 | 01/06/2004 |
| 6583234 | Process for preparing waterfastness additive Disclosed is a process which comprises (a) reacting allyl bromide with diethyl amine in a molar ratio of at least about 1 mole of allyl bromide per about 1.15 moles of diethyl amine and in a molar ratio of no more than about 1 mole of allyl bromide per ab... | 06/24/2003 |
| 6525012 | Liquid laundry detergent compositions having enhanced clay removal benefits The present invention relates to liquid laundry detergent compositions which provide enhance hydrophilic soil cleaning benefits, said compositions comprising: a) from about 0.01 to about 20% by weight, of a zwitterionic polymer which comprises a polyamine... | 02/25/2003 |
| 6426436 | Ether diamines quaternaries The present invention is related to a series of derivatives of novel ether diamine compounds prepared by the cynobutylation reaction of an alcohol having 3 to 22 carbon atoms with 2-pentenenitrile to form a branched alkyl ether nitrile. The etheraminonitr... | 07/30/2002 |
| 6399663 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-depende... | 06/04/2002 |
| 6384097 | Amine catalyst for producing rigid polyurethane foam An amine catalyst for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): ##STR1## where R1 to R6 are independently a linear or branched s... | 05/07/2002 |
| 6384177 | Process for producing polyurethane and polyisocyanurate An amine catalyst for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): ##STR1## where R1 to R6 are independently a linear or branched s... | 05/07/2002 |
| 6379294 | Process for preparing esterquats A process for preparing an esterquat composition comprising (a) reacting a tertiary amine according to formula I: ##STR1## wherein R1 represents a C3 -C6 hydrocarbon group, R2 represents a C3 -C6... | 04/30/2002 |
| 6307102 | Amine catalyst for producing polyurethane and polyisocyanurate An amine catalyst-for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): ##STR1## where R1 to R6 are independently a linear or branched s... | 10/23/2001 |
| 6177577 | Dicationic and polycationic monoprimary alcohols and derivatives thereof This invention relates to novel dicationic and polycationic monoprimary alcohol compounds and their derivatives, represented by the formula ##STR1## wherein each alk is independently alkyl of 1-8 carbon atoms; each ALK is independently alkyl of 1-8 carbon... | 01/23/2001 |
| 5851982 | Liquid softener compositions and quaternary ammonium salt To provide a liquid softener composition which is satisfactory in respects of softening effect, storage stability and water absorption properties, is excellent in biodegradability and is gentle with the environment. A liquid softener composition comprisin... | 12/22/1998 |
| 5824812 | Polyfunctional cationic cytofectins, formulations and methods for generating active cytofectin: polynucleotide transfection complexes Amine containing compounds and their use in the generation of cytofectin:polynucleotide complexes for transfection of cells, formulations, counterions, and reaction conditions for maximizing the transfection include using cationic amine compounds that hav... | 10/20/1998 |
| 5705695 | Quaternary Zintl composition (Et4 N)4 ›Au(Ag1-x Aux)2 Sn2 Te9 ! The quaternary Zintl material (Et4 N)4 ›Au(Ag1-x Aux)2 Sn2 Te9 ! that contains 1-D semiconducting chains composed of four metallic elements is prepared by treating ethylenediami... | 01/06/1998 |
| 5703131 | Method for the detoxification of mustard gas sulfur-containing quaternary ammonium ionene polymers and their use as microbicides A method for the detoxification of a mustard gas by reaction with a bis-tertiary diamine resulting in quaternary ammonium ionene polymers. Sulfur-containing quaternary ammonium ionene polymers which are useful as microbicides for controlling the growth of... | 12/30/1997 |
| 5674908 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-depende... | 10/07/1997 |
| 5650099 | Methods and compositions providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants A dicationic surfactant for enhancing the chemiluminescence of chemiluminescent compounds particularly dioxetanes which are triggerable is described. The surfactant has the formula X- (R1)3 A+ CH2 -Link-CH... | 07/22/1997 |
| 5623088 | Method of preparing 4-aminodiphenylamine A method of producing 4-ADPA is disclosed wherein aniline or substituted aniline derivatives and nitrobenzene are reacted under suitable conditions to produce 4-nitrodiphenylamine or substituted derivatives thereof and/or 4-nitrosodiphenylamine or substit... | 04/22/1997 |
| 5606033 | Displacement chromatography of proteins using low molecular weight anionic displacers A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight anionic species are exemplified, including aromatic rings having sul... | 02/25/1997 |