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| Number | Title | Issue Date |
| 7982070 | Ionizable isotopic labeling reagents for relative quantification by mass spectrometry Relative quantification of metabolites by Electrospray Ionization Mass Spectrometry (ESI-MS) requiring a mechanism for simultaneous analysis of multiple analytes in two or more samples. Labeling reagents that are reactive to particular compound classes and differ on... | 07/19/2011 |
| 7507859 | Functional synthetic molecules and macromolecules for gene delivery The present invention describes a synthetic non-viral vector composition for gene therapy and the use of such compositions for in vitro, ex vivo and/or in vivo transfer of genetic material. The invention proposes a pharmaceutical composition containing 1) a non-cati... | 03/24/2009 |
| 7300545 | Water-soluble polymer dispersion, process for producing the same and method of use therefor A water-soluble polymer dispersion, process for producing the same and a method of use therefor. In particular, the water-soluble polymer dispersion is one comprising water-soluble polymer fine particles of 100 μm or less diameter having at least one ionic property... | 11/27/2007 |
| 7294621 | Lipid analogs for combating tumors The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294620 | Lipid analogs for inhibiting HIV-1 activity The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294619 | Lipid analogs for inhibiting the activity of hepatitis B antigen The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7226501 | Process for the manufacture of a bitumen-aggregate mix suitable for road pavement The present invention relates to an aqueous quick-setting bitumen-aggregate mix suitable for cold pavement of roads, parking places, sidewalks and the like. The bitumen-aggregate mix is manufactured by mixing a mineral aggregate, water, a de-emulsifier, containing h... | 06/05/2007 |
| 7208605 | Functionalized ionic liquids, and methods of use thereof One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze... | 04/24/2007 |
| 7196221 | Ionic liquids and their use Ionic compounds having a freezing point of no more than 50° C., formed by the reaction of at least one amine salt of the formula R1R2R3R4N+X− (I) with at least one hydrated salt, which is a chlorid... | 03/27/2007 |
| 7183433 | Ionic liquids and their use as solvents Ionic compounds with a freezing point of up to 100° C. are formed by the reaction of an one amine salt of formula (I) R1R2R3R4N+X−, such as choline chloride with an organic compound (II) capable of... | 02/27/2007 |
| 7129287 | Clay nanocomposites prepared by in-situ polymerization A method for preparing exfoliated clay nanocomposites by in-situ polymerization comprising the steps of (a) providing a mixture of at least one type of monomer and at least one type of organophilic clay; and (b) initiating an in-situ polymerization reaction in the m... | 10/31/2006 |
| 7002042 | Cationic liposomes for gene transfer The present invention relates to synthetic cationic lipids, liposome formulations and the use of such compounds to introduce functional bioactive agents into cultured cells. ... | 02/21/2006 |
| 6972338 | Alkoxylated mono alkyl glyceryl ester phosphobetaine compounds The invention relates to a series of novel alkoxylated mono alkyl glyceryl ester phosphobetaine compounds, which are exceptional surface active agents that provide outstanding foam and are very mild to the hair and skin, in addition because of the presence of the es... | 12/06/2005 |
| 6967258 | Production of quaternary ammonium salt of hydroxycarboxylic acid and quaternary ammonium salt of inorganic acid A quaternary ammonium hydroxycarboxylate is produced by quaternizing a tertiary amine with a hydroxycarboxylic ester represented by the following Formula 1: wherein R1 to R3 are as defined in the ... | 11/22/2005 |
| 6964940 | Method of preparing quaternized amidoamine surfactants This invention is a method of preparing a quaternized amidoamine surfactant comprising reacting an amidotertiaryamine of formula with methyl halide and alkylene oxide, an aqueous quaternized amidoamine surfactant composition, a gelled aqueous composition comprising ... | 11/15/2005 |
| 6960690 | Process of making a compound by forming a polymer from a template drug A method of forming polymers in the presence of nucleic acid using template polymerization. Also, a method of having the polymerization occur in heterophase systems. These methods can be used for the delivery of nucleic acids, for condensing the nucleic acid, for fo... | 11/01/2005 |
| 6900313 | Chiral ionic liquids The invention relates to chiral ionic liquids of the general formula [A]n+[Y]n−, whereby n=1 or 2, the anion [Y]n− is the anion of an organic or inorganic proton acid and the cation [A]+ ... | 05/31/2005 |
| 6875889 | Monomers with quaternary amino groups, methods for making same, and novel (co)polymers obtained from said novel monomers The invention relates to compounds of formula (I), prepared by quaternising a compound (II) by means of at least one compound R3—X⊖: R1=H or —CH3; R2=—CH | 04/05/2005 |
| 6727388 | Demulsifying compound and a method of breaking or inhibiting emulsions The present invention is a demulsifying and corrosion-inhibiting compound formed from the salt of an amphiphilic amine and an amphiphilic acid. In a preferred embodiment of the invention, the demulsifier may be a salt of an alkyl amine and an alkyl aryl sulfonic aci... | 04/27/2004 |
| 6727387 | Quaternary ammonium salts having a tertiary alkyl group A compound of formula I: ... | 04/27/2004 |
| 6586632 | Preparation of quaternary ammonium compounds Quaternary ammonium dihydrogen phosphate or bisulfate salts are made by a process comprising the steps of: (1) forming a first mixture by contacting a quaternary ammonium halide with: (a) a water-insoluble organic solvent capable of forming a ternary azeo... | 07/01/2003 |
| 6576684 | Thermal- and photoinitiated radical polymerization in the presence of an addition fragmentation agent Disclosed are compositions from which radically initiated oligomers/polymers having a controlled molecular weight, low polydispersity and a vinyl or dienyl end group are prepared. Further subjects of the invention are a process for controlled radical ... | 06/10/2003 |
| 6573024 | Ammonium salt of organic acid and resist composition containing the same The present invention provides a novel ammonium salt of an organic acid. When the salt is used as a base additive for a chemically amplified resist, the environmental stability of the resist can be enhanced, and the T-top phenomenon can be effectively pre... | 06/03/2003 |
| 6545181 | Demulsifying compound and a method of breaking or inhibiting emulsions The present invention is a demulsifying and corrosion-inhibiting compound formed from the salt of an amphiphilic amine and an amphiphilic acid. In a preferred embodiment of the invention, the demulsifier may be a salt of an alkyl amine and an alkyl aryl s... | 04/08/2003 |
| 6538032 | Phytosphingosine derivatives with antitumor activity The present invention relates to an antitumor agent containing a phytosphingosine derivative, and more specifically, to an antitumor agent containing a phytosphingosine derivative of formula I as an active ingredient, ##STR1## wherein R1, ... | 03/25/2003 |
| 6489495 | Cationic amphiphiles for liposomal gene transfer This invention relates to the synthesis of novel cationic, amphiphilic lipids and their application as gene transfer vehicles in vitro and in vivo. For this a series of different lipids (diglycerides, steroids) were synthesized by modification with variab... | 12/03/2002 |
| 6458381 | Lipids and their use, for example, in liposomes The invention concerns novel lipid compounds suitable for the transport of biologically active substances or molecules in cells. A preferred compound according to the invention is L-lysine-bis-(O,O'-cis-9-octadecenoyl-ଲ-hydroxyethyl)-amide dihy... | 10/01/2002 |
| 6414170 | Preparation of cationic surfactants containing ester group in molecules The present invention relates to a method for preparing a cationic surfactant in which physical chemical characteristics such as softness, antistatic properties, etc. as well as biodegradability are quite excellent due to having an ester group and a hydro... | 07/02/2002 |
| 6384177 | Process for producing polyurethane and polyisocyanurate An amine catalyst for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): ##STR1## where R1 to R6 are independently a linear or branched s... | 05/07/2002 |
| 6384097 | Amine catalyst for producing rigid polyurethane foam An amine catalyst for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): ##STR1## where R1 to R6 are independently a linear or branched s... | 05/07/2002 |
| 6362370 | Wood preservatives Wood preservatives having biocidal properties which include quaternary ammonium compounds of general formula (I): ##STR1## wherein R1 is a C8-18 -alkyl group or an optionally substituted benzyl group, R2 is a C8-18 | 03/26/2002 |
| 6353137 | Stable aromatic amine composition, a process for preparing color stable aromatic amines, and the production of light colored aromatic amine-based polyether polyols This invention relates to stable aromatic amine compositions. These compositions comprise a) an organic compound containing at least one carboxylic acid group, and b) an aromatic amine. This invention also relates to a process for stabilizing the color of... | 03/05/2002 |
| 6307102 | Amine catalyst for producing polyurethane and polyisocyanurate An amine catalyst-for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): ##STR1## where R1 to R6 are independently a linear or branched s... | 10/23/2001 |
| 6235914 | Amine and quaternary ammonium compounds made from ketones and aldehydes, and compositions containing them A process for making a tertiary amine ester of the following formula (I): ##STR1## the process comprising: (a) reacting a ketone or an aldehyde having the formula ##STR2## with a glycol to form a ketal or an acetal; (b) reacting the ketal or the acetal with a... | 05/22/2001 |
| 6198000 | Intermediates useful in the synthesis of quinoline antibiotics A process for preparing a compound of the formula ##STR1## wherein R1, m, o and p are described below, which comprises adding a base of the formula ##STR2## wherein R2, R3 and R4 are as described below, to a sol... | 03/06/2001 |
| 6194606 | Intermediates The present invention provides compounds having the formula: ##STR1## in which R is hydrogen or C1 -C4 alkyl, preferably hydrogen and Y is hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy, CF3, ... | 02/27/2001 |
| 6087303 | Quaternary ammonium carboxylate and borate compositions and preparation thereof Wood preservative systems comprising (a) a biocidal effective amount of (i) at least one di C8 -C12 alkyl quaternary ammonium carboxylate having the formula ##STR1## wherein R1 and R2 are a C8 -C... | 07/11/2000 |
| 6072063 | Low-melting ester quats Ester quats of the formula (1) below are described: ##STR1## where RCO is an aliphatic acyl radical having 6 to 22 carbon atoms, R1 is a methyl radical, R2 is a C1 -C6 -alkyl radical, R3 is a C | 06/06/2000 |
| 6057455 | Preparation of intermediates useful in the synthesis of quinoline antibiotics A process for preparing a compound of the formula ##STR1## wherein R1, m, o and p are described below, which comprises adding a base of the formula ##STR2## wherein R2, R3 and R4 are as described below... | 05/02/2000 |
| 6054615 | Fluorinated quaternary ammonium salts Selected quaternary ammonium salts containing fluoroalkyl, preferably perfluoroalkyl, groups that are stable to bases are described. They are useful as phase transfer reaction catalysts, especially in basic media.... | 04/25/2000 |
