Class 564/236 - Polyguanidines

Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein there are at least two guanidine groups.
No. of patents: 33
Last issue date: 10/28/2008

Number	Title	Issue Date
7442682	Transepithelial delivery of peptides with incretin hormone activities Compositions and methods are disclosed for the treatment of diabetes and related diseases using peptides with incretin hormone activity. Preferably, the peptide with incretin hormone activity is GLP-1, exendin or an analog of GLP-1 or exendin. The peptides with incr...	10/28/2008
7323594	Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro...	01/29/2008
7166745	Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro...	01/23/2007
7067698	Bi-directional synthesis of oligoguanidine transport agents Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds ...	06/27/2006
7022214	Carrier ampholytes of high pH range Carboxylic acid-substituted polyalkylene polyamines in which amine nitrogen atoms on the polyamine backbone structure are replaced by guanidine groups provide a pH range extending into high pH values. These substances are useful as carrier ampholytes in isoelectric ...	04/04/2006
6669951	Compositions and methods for enhancing drug delivery across and into epithelial tissues This invention provides compositions and methods for enhancing delivery of drugs and other agents across epithelial tissues, including the skin, gastrointestinal tract, pulmonary epithelium, ocular tissues and the like. The compositions and methods are al...	12/30/2003
6423748	Amido polybiguanides and the use thereof as antimicrobial agents Amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of amido polybiguanides is also disclosed. The amido polybiguanides are useful in the preservation of pharmaceutical composition...	07/23/2002
6316669	Bis-amido polybiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions Bis-amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of bis-amido polybiguanides is also disclosed. The bis-amido polybiguanides are useful in the preservation of pharmaceutical...	11/13/2001
6114392	Agmatine, and polyaminoguanidine-bound heterocyclic compounds for neurotrauma and neurodegenerative diseases The invention relates to the use of agmatine, in the treatment of acute neurotrauma (such as stroke) and degenerative disorders of the central and peripheral nervous system (such as dementia). The invention further provides novel compounds of general formula I...	09/05/2000
5910549	Method for preparation of alkoxyamines from nitroxyl radicals An improved process for free radical polymerization is produced making it possible to control the growth steps of a polymerization to produce homopolymers and copolymers, including block and graft copolymers. The process uses a long half-life radical init...	06/08/1999
5830917	L-N⁶ -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors There is disclosed a novel amino alcohol amine derivatives of L-N6 -(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors....	11/03/1998
5646188	Polyamine derivatives of 1-aminoindan A compound of general formula I ##STR1## wherein n is 1 or 2; R1 and R2 are each independently hydrogen, hydroxy, substituted or unsubstituted C1-4 alkyl, substituted or unsubstituted C1-4 alkoxy or halogen...	07/08/1997
5637621	Methods and compositions for treating Botrytis infections The invention provides fungicidal compounds having the general formula: X1 -A1 -B1 -C-B2 -A2 -X2 (I) wherein X1 is an amidine, a guanidine, or an imidazole group. A1 is either a ...	06/10/1997
5629348	Methods and compositions for treating septoria infections The invention provides fungicidal compounds having the general formula: X1 -A1 -B1 -C-B2 -A2 -X2 (I) wherein X1 is an amidine, a guanidine, or an imidazole group. A1 is either a...	05/13/1997
5627194	Anti-viral guanidino-substituted compounds Novel guanidino-substituted compounds are described having the following general formula (I): ##STR1## in which X may be carbon, oxygen, nitrogen or sulfur; R1 may be H, OH, linear or branched lower alkyl, lower alkoxy, lower (alkyl-substi...	05/06/1997
5599984	Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv...	02/04/1997
5496480	Ashless dispersants comprising reaction product of acylating agent and aminoguanidine Ashless dispersants are formed using polymers of propylene characterized in that they are liquid substantially linear polymers, they have stereo-irregularity in the polymer chain, at least 60 mol percent of the polymer has a terminal vinylidene group and,...	03/05/1996
5420350	Bis-biguanide compound useful as a disinfectant A novel bis-biguanide compound suitable for use as a disinfectant has the following formula: ##STR1## where n is an integer from 2 to 10 inclusive. A pharmaceutically acceptable salt, particularly gluconate salt of the compound is also useful as...	05/30/1995
5214208	Toner containing a dimer of diarylguanidine type compound for developing electrostatic image A toner for developing an electrostatic image comprises a binder resin and a dimer of a diarylguanidine type compound. The dimer is represented by the general formula (I) below: ##STR1## wherein R1, R2, R3, R4	05/25/1993
5081298	Bis(pentaalkylguanidinium) alkane salts as phase transfer catalysts ଱,ω-Bis(pentaalkylguanidinium) alkane salts such as 1,6-bis (penta-n-butylguanidinium) hexane dibromide are prepared by the reaction of a tetraalkyl urea with phosgene or phosphorus oxychloride, or by the reaction of a tetraalkyl thiourea with an N...	01/14/1992
5059624	Guanidine derivatives having hypotensive activity, composition containing them and process for obtaining them Guanidine derivatives of the following formulas (1) and (2): ##STR1## wherein: R1 is hydrogen or optionally substituted cinnamoyl, R2 is hydrogen, alkyl or alkenyl, with the proviso that R1 and R2 cannot be both...	10/22/1991
5023107	Hard tissue surface treatment A method of improving the adhesion of an adhesive to the surface of hard tissue. Before the adhesive is applied, the hard tissue surface is primed with a polybiguanide or an addition salt thereof, or is pretreated with an aqueous solution of a magnesium s...	06/11/1991
4981965	Process for formation of base A base precursor in the form of a salt of an organic base with a carboxylic acid is disclosed. The organic base is a diacidic to tetraacidic base which is composed of two to four guanidine moieties and at least one linking group for the guanidine moities....	01/01/1991
4694086	Guanidine derivatives The novel guanidine derivative compounds having a molecular structure consisting of an aliphatic hydrocarbon chain wherein the guanidino group ##STR1## is bonded with the primary carbon atoms existing at the both ends thereof, and having an amino gro...	09/15/1987
4567174	Bis(1-substituted biguanide) derivatives A bis(1-substituted biguanide) derivative of the formula: or a tautomeric form thereof, wherein R1, R2 and R9, which may be the same or different, are each hydrogen, a 1-16C alkyl radical, a 3-16C cycloalkyl radical, a (3-12C c...	01/28/1986
4540497	Fluoroaliphatic radical-containing, substituted guanidines and fibrous substrates treated therewith Novel fluoroaliphatic radical-containing, substituted guanidines useful in the form of organic solutions or aqueous dispersions in the treatment of fibrous substrates, such as textile fibers, to impart oil and water repellency....	09/10/1985
4339459	Guanidinium compounds and their use as microbiocidal agents Guanidiunium salts of the formula 1 ##STR1## in which R1 and R2 are identical or different and denote alkyl, 2-hydroxyalkyl or alkenyl each having from 8 to 18 carbon atoms, or C8 -C18 alkoxypropyl, m and n...	07/13/1982
4317819	Amine derivatives The invention provides compounds of general formula ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which Y and Z, which may be the same or different, each represent oxygen, sulphur, .dbd.CHNO2 or .dbd...	03/02/1982
4258181	Substituted 9,10-anthracenebishydrazones This disclosure describes anthracene-9,10-bis-carbonyl-hydrazones and derivatives thereof useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors, and for inducing the regression and/or palliation of leukemia and related can...	03/24/1981
4166827	Bis-carbamylguanidinoazaalkane antimicrobial compounds Antimicrobial compounds are disclosed having the formula: wherein B is carbamylguanidino or thiocarbamylguanidino; Y is an alkylene group which contains one to three nitrogen atoms or which contains two nitrogens as part of a cyclic structure; and Z can repres...	09/04/1979
4110328	Bis-carbamylguanidinoazaalkane antimicrobial compounds Antimicrobial compounds are disclosed having the formula: wherein B is carbamylguanidino or thiocarbamylguanidino, Y is a nitrogen-containing alkylene group having the structural formula: ##STR1## WHEREIN: N = 2-4 m = 2-4 p = 1,2 q = 2-4 x = 0-3 y = 0-2 x...	08/29/1978
4092432	Mixtures having antimicrobial or pesticidal effect The present invention relates to mixtures of guanidated aliphatic polyamines, or their acid addition salts, having antimicrobial or pesticidal effect. More particularly the invention relates to such mixtures which have a total degree of guanidation exceed...	05/30/1978
4022698	Bis-(guanidine)-tetrabromodian and its production Tetrabromobisphenol A dissolved in aqueous alkalide solution is reacted with an aqueous guanidine carbonate solution to produce bis-(guanidine)-tetrabromodian having the following formula ##STR1## which compound has flame retardant properties....	05/10/1977

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Class 564/236 - Polyguanidines