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| Number | Title | Issue Date |
| 7932422 | Use of chlorine guanabenz derivatives for treating polyglutamine expansion associated diseases The invention relates to chlorine Guanabenz derivatives for treating Huntington's disease and other polyglutamine expansion associated diseases. More specifically, it relates to the use of the molecule of formula (I) wherein R═H or Cl and the phenyl group is at le... | 04/26/2011 |
| 7291647 | Guanylhydrazone compounds, compositions, methods of making and using The present invention relates to compounds having the formula: salts thereof; compositions comprising one or more of the compounds and/or salts thereof; methods of using; and methods of m... | 11/06/2007 |
| 6660246 | Ligands and metal complexes thereof Novel compounds of the formula ##STR1## and novel complexes of these compounds with metals are useful in diagnostic and therapeutic methods.... | 12/09/2003 |
| 6284798 | Guanidine derivatives, methods of preparing them and their use as drugs The invention concerns new guanidine derivatives of formula (I), methods of preparing them and their use in drugs containing compounds, of formula (I), wherein ##STR1## wherein x is --NH--NH--CH2 R1 and R1 denotes C8 | 09/04/2001 |
| 6211304 | Mordants for ink-jet receptors and the like Novel mordants based upon a poly(alkylene oxide) backbone and either pendant phosphonium or quaternized-nitrogen compounds are disclosed. The mordants find use in stopping or controlling ink-bleeding in ink-jet receptors and photographic films.... | 04/03/2001 |
| 6180676 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 01/30/2001 |
| 6136987 | Use of arylguanidinium xanthogenates as vulcanization accelerators and process for the production thereof This invention relates to the use of arylguanidinium xanthogenates as vulcanization accelerators, to a process for the production thereof and to the arylguanidinium xanthogenates.... | 10/24/2000 |
| 6114392 | Agmatine, and polyaminoguanidine-bound heterocyclic compounds for neurotrauma and neurodegenerative diseases The invention relates to the use of agmatine, in the treatment of acute neurotrauma (such as stroke) and degenerative disorders of the central and peripheral nervous system (such as dementia). The invention further provides novel compounds of general formula I... | 09/05/2000 |
| 6063819 | Neuroprotective poly-guanidino compounds which block presynaptic N and P/Q calcium channels Neuroprotective drugs are disclosed with at least 3 branches extending outwardly from a center atom or group, each branch having a guanidino group at its terminus. All branches preferably should be identical, and distributed around the center atom or grou... | 05/16/2000 |
| 5856571 | Semicarbazide-containing linker compounds for formation of stably-linked conjugates and methods related thereto Linker compounds for formation of stably-linked conjugates are disclosed. Such linker compounds are semicarbazide-containing linker compounds useful in forming conjugates having stable semicarbazone linkages. The stably-linked conjugates have utility in a... | 01/05/1999 |
| 5852009 | Compositions, including pharmaceutical compositions, for inhibiting the advanced glycosylation of proteins, and therapeutic methods based thereon The present invention relates to compositions and methods for inhibiting protein aging. Accordingly, a composition is disclosed which comprises an agent or compound capable of inhibiting the formation of advanced glycosylation end products of target prote... | 12/22/1998 |
| 5837737 | Hydrazinedicarboximidamide compounds and pharmaceutical composition comprising same Modulators of neurotransmitter release including substituted guanidines, N"-aminoguanidines, and N,N'N",N"'-tetrasubstituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use o... | 11/17/1998 |
| 5753684 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 05/19/1998 |
| 5714617 | Processes for producing a salt of N-guanidino thiourea and 3-amino-5-mercapto-1,2,4-triazole A method for producing 3-amino-5-mercapto-1,2,4-triazole, useful as an intermediate compound for a medicine or pesticide, or the intermediate thereof, a salt of N-guanidino thiourea from aminoguanidine thiocyanate or a thiocyanate and an aminoguanidine co... | 02/03/1998 |
| 5705531 | 1,5-disubstituted 7A-methylperhydroinden-3A-ol derivatives, useful in treating cardiovascular disorders, processes for their preparation and pharmaceutical compositions containing the same 1,5-Disubstituted 5a-methylperhydroinden-3a-ol derivatives of formula (I): ##STR1## where either the symbol - - - - represents a single bond, the group A is in cis configuration with respect to the 3a-hydroxy, 7a-methyl and 1-L groups, and A is (CH.dbd.CH... | 01/06/1998 |
| 5698563 | Bis-hydrazones! The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises bis(guanylhydrazone) of the formula ##STR1## capable of inhibiting the format... | 12/16/1997 |
| 5693673 | Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene)bishydrazine caroximidamide! Process for the preparation of 2,2'-(1-methyl 1,2-ethanediylidene)bishydrazine carboximidamide! by: a) reacting aminoguanidine hydrochloride with methylglyoxal aldehyde or methylglyoxal dimethyl acetal; and b) purifying the 2,2'-(1-methyl-1,2-ethanediylidene... | 12/02/1997 |
| 5639911 | Hydrazones Compounds of formula I ##STR1## wherein A, X, Z and R1 -R5 are as defined in the description, and their salts have valuable pharmaceutical properties and are effective especially against tumours. They are prepared in a manner kn... | 06/17/1997 |
| 5612332 | Di- and triaminoguanidines, and methods of use The present invention relates to compounds, compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises a di- or tri-aminoguanidine capable of inhibiting the formation of adva... | 03/18/1997 |
| 5599984 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 02/04/1997 |
| 5559243 | Processes for producing a salt of N-guanidino thiourea and 3-amino-5-mercapto-1,2,4-triazole A method for producing 3-amino-5-mercapto-1,2,4-triazole, useful as an intermediate compound for a medicine or pesticide, or the intermediate thereof, a salt of N-guanidino thiourea from aminoguanidine thiocyanate or a thiocyanate and an aminoguanidine co... | 09/24/1996 |
| 5494934 | Guanidine compounds A compound of formula (I): ##STR1## in which: R1 represents substituted or unsubstituted phenyl or (C3 -C7) cycloalkyl, R2 represents trifluoromethyl or (C3 -C4) cycloalkyl, A represents --... | 02/27/1996 |
| 5478946 | Guanidino compounds as regulators of nitric oxide synthase Compounds of the formula: ##STR1## useful as regulators of nitric oxide synthase that indirectly modulate cyclic guanosine monophosphate (cGMP), pharmaceutical compositions thereof, for treating disorders of vascular smooth muscles, macrophages, ... | 12/26/1995 |
| 5464858 | Heme binding compounds and use thereof Inhibitors of nitric oxide formation from arginine useful for treating hypotension, inflammation, stroke and to restore vascular contractile sensitivity to the effects of 댑 adrenergic agonists are physiologically active compounds includi... | 11/07/1995 |
| 5461076 | Hydrazones Compounds of formula I ##STR1## wherein A, X, Z and R1 -R5 are as defined in the description, and their salts have valuable pharmaceutical properties and are effective especially against tumors. They are prepared in a manner kno... | 10/24/1995 |
| 5444082 | 3,9-disubstituted-spiro(5.5)undecanes active on the cardiovascular system, process for their preparation and pharmaceutical composition containing same 3,9-disubstituted-spiro[5.5]undecanes and ##STR1## wherein, R, Y, A, B and n are defined in the specification, pharmaceutical compositions containing same for the treatment of cardiovascular disorders, such as heart failure and hypertension, are disc... | 08/22/1995 |
| 5403955 | Mordants for ink-jet receptors and the like Novel mordants based upon a polyethyleneimine backbone and either pendant phosphonium or quaternized-nitrogen compounds are disclosed. The mordants find use in stopping or controlling ink-bleeding into ink-jet receptors and photographic films.... | 04/04/1995 |
| 5395855 | Hydrazones Compounds of formula I ##STR1## wherein A, X, Z and R1 -R5 are as defined in the description, and their salts have valuable pharmaceutical properties and are effective especially against tumors. They are prepared in a manner kno... | 03/07/1995 |
| 5380945 | Guanidino compounds as regulators of nitric oxide synthase Compounds of the formula: ##STR1## useful as regulators of nitric oxide synthase that indirectly modulate cyclic guanosine monophosphate (cGMP), pharmaceutical compositions thereof, for treating disorders of vascular smooth muscles, macrophages, ... | 01/10/1995 |
| 5296498 | Guanidine compounds A compound of formula (I): ##STR1## in which: R1 represents substituted or unsubstituted phenyl or (C3 -C7) cycloalkyl, R2 represents trifluoromethyl or (C3 -C4) cycloalkyl, A represents --... | 03/22/1994 |
| 5200541 | Non-centrosymmetric organometallic molecules, process of preparation and application in nonlinear optics and intermediates The products having general formula (I) ##STR1## in which R represents a C1 -C18 alkoxyl, C1 -C18 alkylthio, C1 -C18 monoalkylamino or C2 -C36 dialkylamino group,... | 04/06/1993 |
| 5087733 | Sulfur containing quaternary ammonium salts as hair conditioning agents Processes for conditioning human hair by treatment with selected sulfur containing quaternary ammonium compounds, compositions useful for such processes and novel quaternary compounds useful in the processes.... | 02/11/1992 |
| 5041661 | Method of producing triaminoguanidine nitrate A process for preparing triaminoguanidine nitrate from relatively impure -99 percent)/commercial guanidine nitrate and commercial grade aqueous hydrazine (50-64 weight percent) in alcohol by: (1) adding enough hydrazine to form monoaminoguanidine nitrate... | 08/20/1991 |
| 4906778 | Process for the production of aminoguanidine bicarbonate A process for the preparation of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting there... | 03/06/1990 |
| 4800232 | Process for producing triaminoguanidine nitrate and the high melting point product so produced A process for producing triaminoguanidine nitrate, and, more specifically, a process which involves reacting hydrazine, nitric acid and cyanamide in specified molar ratios. Also claimed is the high melting point product so produced.... | 01/24/1989 |
| 4295982 | Sulfurized aminoguanidine reaction product and lubricant compositions containing same Products from aminoguanidines or their salts, monocarboxylic acids and sulfur and their use as anti-rust and anti-corrosion additives are covered herein.... | 10/20/1981 |
| 4113775 | Triaminoguanidinium salt of tetranitroethane An energetic salt of tetranitroethane and triaminoguanidine which can be used as a high energy solid propellant oxidizer.... | 09/12/1978 |
| 3950421 | Method of producing triaminoguanidine nitrate A method of producing triaminoguanidine nitrate wherein a source of free nitrate ions is provided in an aqueous medium during reaction of guanidine nitrate and hydrazine to increase the yield of triaminoguanidine nitrate.... | 04/13/1976 |
| 3939272 | Solubilizing process for oil insoluble pesticides This invention concerns a process for converting normally oil-insoluble, nitrogen-containing pesticidal compounds to oil-soluble complexes by treatment with alkylated phenols, and to the oil-soluble complexes resulting therein.... | 02/17/1976 |
