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| Number | Title | Issue Date |
| 7279597 | Phenyl amine carboxylic acid compounds and compositions for delivering active agents Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/09/2007 |
| 7183432 | Synthesis of ynamides A method of synthesizing diacetylenic amides is described. The key steps of the invention include the reaction of an aldehyde with the monoanion of a diacetylene and the reductive removal of a propargylic alcohol. The invention offers the first known method of synth... | 02/27/2007 |
| 7157603 | Method for the separation of oligomeric N-substituted (meth)acrylamide compounds and conjugates thereof which are reversibly thermally precipitating The method of separating reversibly thermally precipitable oligomeric N-substituted (meth)acrylamides and conjugates thereof from aqueous solution includes thermally precipitating the oligomeric N-substituted (meth)acrylamides and the conjugates thereof from an aque... | 01/02/2007 |
| 7129274 | Phenoxy carboxylic acid compounds and compositions for delivering active agents Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/31/2006 |
| 6967250 | Energy transfer dyes Energy transfer dyes, their preparation, and their use as labels in biological systems is disclosed. The dyes are preferably in the form of cassettes which enable their attachment to a variety of biological materials. The dyes and the reagents that can be made from ... | 11/22/2005 |
| 6960355 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 11/01/2005 |
| 6750368 | Process for preparing sulphuric methacrylamide and device for implementing it The present invention relates to a process for preparing sulphuric methacrylamide. The process can include adding sulphur trioxide and a second part of acetone cyanohydrin without sulfuric add to a reaction medium, after a first part of acetone cyanohydrin with sulp... | 06/15/2004 |
| 6562963 | Process for the preparation of macrocyclic metalloprotease inhibitors The present invention is directed to a process for the preparation of a compound of formula (X-a) ##STR1## or a pharmaceutically acceptable salt form thereof, wherein: R1 is selected from the group consisting of: C1-5 alkyl substituted wi... | 05/13/2003 |
| 6552226 | Tandem acyl-Claisen rearrangement in the preparation of chiral products A novel tandem acyl-Claisen rearrangement reaction is provided. An allylic reactant such as an allylic amine or an allylic thioether, having at least two functional groups that enable the reactant to undergo at least two successive Claisen rearrangement r... | 04/22/2003 |
| 6506939 | Production of acrylic monomers A process for the preparation of a mixture comprising a compound of formula (1) and a compound of formula (2) ##STR1## wherein R1 is an optionally substituted C1-20 alkyl, optionally substituted C3-4 alkenyl, optionally su... | 01/14/2003 |
| 6166253 | Process for producing N-(1-alkoxyethyl)carboxylic amides A process for producing N-(1-alkoxyethyl)carboxylic amides by reacting alcohols of 1-5 carbon atoms with N-vinylcarboxylic amides in the presence of an acidic catalyst, or by utilizing unreacted starting material, unreacted intermediate or unrecovered pro... | 12/26/2000 |
| 5852214 | Process for producing n-(1-alkoxyethyl) carboxylic amides A process for producing N-(1-alkoxyethyl)carboxylic amides by reacting alcohols of 1-5 carbon atoms with N-vinylcarboxylic amides in the presence of an acidic catalyst, or by utilizing unreacted starting material, unreacted intermediate or unrecovered pro... | 12/22/1998 |
| 5723665 | Ethenyl amide compound production process A process for producing an ethenyl amide compound, which comprises reacting a Schiff base compound having a carbon atom adjacent to a carbon atom constituting an imino group and at least one hydrogen atom on the carbon atom with an acylhalide at a reduced... | 03/03/1998 |
| 5587515 | Method of manufacturing N-monosubstituted (meth)acrylamides A process for producing N-monosubstituted acrylamides in high yields without forming by-products. The process comprises preparing a ଲ-dialkylamino-(methyl)propionic ester by the reaction of a (meth)-acrylic ester with a specified dialkylamine, conve... | 12/24/1996 |
| 5567716 | Trans and cis traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity Traumatic acid salts, wherein B is a cation selected from: a) a quaternary ammonium, b) a cation of a linear or branched C1 -C20 mono-, di- or trialkanolamine, c) a cation of a biologically active primary, secondary or tertiary amine, d) silve... | 10/22/1996 |
| 5538998 | Halopropiolamide compound, production and use thereof There are provided with a novel N-substituted-3-halopropiolamide compound, a method of producing the compound, and a composition for controlling noxious organisms containing the compound. The present compound exhibits superior antimicrobial and antifungal... | 07/23/1996 |
| 5312984 | Amidation of vinyl chloride with dimethylamine using a supported palladium catalyst A continuous process for making N,N-dimethylacrylamide (NNDMA) is disclosed which uses a commodity chemical, namely vinyl chloride (VCl), which is amidated with dimethylamine (DMA) and carbon monoxide in the presence of a supported palladium(O) triorganop... | 05/17/1994 |
| 5180851 | Preparation of N-(l-alkoxyalkyl)formamide and alkylidene bisformamides using amine neutralized ion exchange resins This invention relates to an improved process for the formation of N-(l-alkoxyalkyl)amides with coproduction of alkylidene bisamides. The N-(l-alkoxyalkyl)formamides of this invention are prepared by reacting formamide with an acetal or hemiacetal carboxy... | 01/19/1993 |
| 5177264 | Process for preparing an N-substituted (meth)acrylamide derivative An N-substituted dialkylacetal (meth)acrylamide of formula II: ##STR1## wherein n represents 3 or 4; R1 represents hydrogen or methyl; and R2 represents an alkyl of 1 to 3 carbon atoms is prepared by thermally decomposing an ami... | 01/05/1993 |
| 5166434 | Process for the preparation of aromatic-substituted unsaturated amides A process is disclosed for preparing aromatic-substituted unsaturated amides. The process comprises treating a compound of the formula ##STR1## where Ar is C6 to C10 aryl unsubstituted or substituted with at least one halo, amin... | 11/24/1992 |
| 5159113 | Process for the palladium-catalyzed amidation of vinyl chloride A unique two-step process is disclosed for the surprisingly high rate of amidation of vinyl chloride (VCl) with carbon monoxide and certain amines catalyzed by an effective amount of monodentate tertiary phosphonium complexes of Pd(0). The rate is orders ... | 10/27/1992 |
| 4933449 | Preparing 3-(4 chlorophenyl)-3-(3,4-dimethoxyphenyl) acrylic acid morpholide in the presence of potassium tert-butylate The invention provides a process for the preparation of 3,3-diaryl acrylic acid amides of the formula ##STR1## in which A, B and Q are as defined in the specification, characterized by condensing a compound of formula ##STR2## with a compou... | 06/12/1990 |
| 4898977 | Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives The invention relates to novel processes and intermediates for the preparation of 5-amino-4-hydroxyvaleric acid derivatives of the formula ##STR1## in which R1 represents hydrogen, optionally substituted alkyl, cycloalkyl, cycloalkyl-lower... | 02/06/1990 |
| 4835312 | Production process of N-substituted amide compounds An N-substituted amide compound is produced with a high yield by initiating a reaction among a starting amide compound such as a saturated or unsaturated, aliphatic or aromatic carboxylic acid amide, a halogen-substituted compound such as an alkyl halide ... | 05/30/1989 |
| 4644083 | Process for the production of N-substituted ,ଲ-unsaturated carboxylic acid amides The present invention relates to a process for the production of N-substituted ,ଲ-unsaturated carboxylic acid amides, which proceeds from the ,ଲ-unsaturated carboxylic acid amide that is unsubstituted at the amido nitrogen, which... | 02/17/1987 |
| 4605740 | Process for the production of N-substituted acrylic acid amides The present invention relates to a process for the production of N-substituted acrylic acid amides by conversion of 2-carboalkoxy-t-oxabicyclo(2,2,1)hept-5-enes with primary or secondary amines to 2-carboxamide-7-oxabicyclo(2,2,1)hept-5-enes and the therm... | 08/12/1986 |
| 4570018 | Fluorocyclopropanes A novel chemical, fluorochlorocyclopropane (I) of the following formula: ##STR1## is prepared by the addition of fluorochlorocarbene to the corresponding olefin (II) of the following formula: The compound is a useful intermediate for synthesizing some che... | 02/11/1986 |
| 4565889 | Process for the production of N-(3-dimethylaminopropyl)methacrylamide N-(3-dimethylaminopropyl)methacrylamide is prepared by the non-catalytic pyrolysis of N-(3-dimethylaminopropyl)-3-dimethylaminopropyl-2-methyl propionamide in a closed reactor. The N-(3-dimethylaminopropyl)methacrylamide is not removed from the reaction ... | 01/21/1986 |
| 4554377 | Production of N-vinyl carboxylic acid amides The invention relates to the preparation of N--alkoxyethyl-carboxylic acid amides from dimethyl acetal and a carboxylic acid amide such as acetamide and to the preparation of secondary N-vinyl carboxylic acid amides such as N-vinyl acetamide t... | 11/19/1985 |
| 4408073 | Process for preparation of , ଲ-unsaturated N-substituted-carboxylic acid amides The invention relates to a process for the preparation of , ଲ-unsaturated N-substituted carboxylic acid amides, novel , ଲ-unsaturated N-substituted carboxylic acid amides, a process for the polymerization of these novel , ... | 10/04/1983 |
| 4347379 | Synthesis of alpha-alkoxycarboxylic acids Numerous alpha-carboxylic acids are prepared in a liquid medium by the reaction of an organic compound having at least one reactive hydroxyl or thiol group, with a monoketone, and a haloform, in the presence of a phase transfer catalyst and an alkali meta... | 08/31/1982 |
| 4330482 | Process for the preparation of halogenoalkenes In the process for the production of a halogenoalkene of the formula ##STR1## in which R1 is an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aralkyl, aralkenyl or aryl radical or an optionally substituted heter... | 05/18/1982 |
| 4312998 | Method for making N-substituted acrylamides The invention relates to a process for the preparation of N-substituted acrylamides of the general formula ##STR1## wherein Y denotes a bivalent straight - or branched chain radical with 2 to 30, preferably 2 to 18, and particularly 2 to 6 carbon ato... | 01/26/1982 |
| 4302584 | Preparation of 3,3-dimethyl-pent-4-enoic acid amides A process for the preparation of 3,3-dimethyl-pent-3-enoic acid amides of the formula I ##STR1## where R1 and R2 may be identical or different and each is alkyl of 1 to 4 carbon atoms, or R1 and R2 together... | 11/24/1981 |
| 4287363 | Preparation of N-(alkylaminoalkyl)acrylamides A catalytic process for the preparation of N-(alkylaminoalkyl)acrylamides is disclosed which comprises subjecting a corresponding ଲ-aminopropionamide to a temperature of about 100°-250° C. in presence of a catalyst comprising a magnesium, calcium ... | 09/01/1981 |
| 4286105 | Process for the preparation of antioxidant amides An inexpensive and nonhazardous process for the preparation of an amide wherein an organic acid reacting with an aryl amine to form an intermediate hydroxy aryl amide and then dehydrating the hydroxy aryl amide to form a , ଲ unsaturated amide... | 08/25/1981 |
| 4267372 | Preparation of N-substituted acrylamide monomers having cationic substituents Reaction of a beta-aminopropionamide with an acrylic acid or its derivative provides an N-substituted acrylamide monomer having cationic substituents attached thereto. The instant reaction occurs under mild processing conditions at a temperature between a... | 05/12/1981 |
| 4237067 | Process for the manufacture of ,ଲ-unsaturated N-substituted carboxylic acid amides Process for the manufacture of ,ଲ-unsaturated N-substituted carboxylic acid amides of the general formula ##STR1## in which R1 represents H or CH3 R2 represents H or CH3, and Y represents a divalent... | 12/02/1980 |
| 4147718 | Method for making methacrylic acid, its nitrile and its esters In the method of making a compound of the formula ##STR1## wherein X is carboxyl, a carboxylic acid ester group --COOR2, or cyano, by reaction of a compound of the formula CH3 CH2 X with methylal in the presence of a ... | 04/03/1979 |
| 4031138 | Stable substituted acrylamides or methacrylamides Covers a new composition of matter comprising a stable N-(ω-monoalkylaminoalkyl) acrylamide or methacrylamide monomer characterized by the following structural formula: ##STR1## where R1 and R2 are hydrogen or methyl, R3 | 06/21/1977 |
