Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 7626056 | Cyclohexanesulfonyl derivatives as GlyT1 inhibitors to treat schizophrenia The present invention provides compounds of formula I: wherein R1 is an alkyl, phenyl, heterocyclyl, cycloalkyl, alkoxy, ester, amino or amide group; R2 is a phenyl, heterocycly... | 12/01/2009 |
| 7371887 | Oligo(p-phenylene vinylene) amphiphiles and methods for self-assembly Amphiphilic oligo(p-phenylene vinylene) compounds and methods of use en route to self-assembled composites and device fabrication. ... | 05/13/2008 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7265246 | Indane derivates as muscarinic receptor agonists The present invention relates to compounds of Formula I: I which are agonists of the M-1 muscarinic receptor ... | 09/04/2007 |
| 7166746 | N-bisaryl- and n-aryl-cycloakylidenyl-αhydroxy-and α-alkoxy acid amides The invention relates to N-bisaryl- and N-aryl-cycloalkylidenyl-a-hydroxy- and a-alkoxy acetic acid amides of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, C1–C12 | 01/23/2007 |
| 7094808 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment Polyamines having the formula: or a salt thereof with a pharmaceutically acceptable acid wherein: R1-R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having ... | 08/22/2006 |
| 7045579 | Coating composition comprising an acetal-functional binder The invention relates to a coating composition comprising an acetal-functional binder and a thiol-functional cross-linker, wherein the acetal-functional binder is represented by the following formula wherein P is... | 05/16/2006 |
| 7030272 | β-hydroxyalkylamides process for their production and their use This invention relates to a β-hydroxyalkylamide having the general Formula I: where R1 is H or a linear or branched C1 to C10 alkyl and R2 is a linear or branched C1 to C | 04/18/2006 |
| 6936736 | Amide derivative A compound of the formula: wherein Ar is optionally substituted phenyl, etc.; n is 0, 1 or 2; R1 is hydogen atom, optionally substituted alkyl, etc.; R2 and R | 08/30/2005 |
| 6891049 | Method for producing N-alkoxy-N-alkylamides The method for producing N-alkoxy-N-alkylamides of general formula (I): wherein R1 represents C1-10-alkyl, cyclo-C5-7-alkyl, cyclo-C5-7-alkenyl, C2-10-alkenyl, ary... | 05/10/2005 |
| 6790965 | Combinatorial dihydrobenzopyran library Combinatorial libraries are disclosed which are represented by Formula I: (T′—L)q—Ŝ—C(O)—L′—II′ I wherein: Ŝ is a solid support; T′—L— is an identifier residue; and —L′—II′ is a l... | 09/14/2004 |
| 6716881 | Carbanilides used as pesticides The present invention provides carbanilides of formula (I), wherein A, Q, R, X, Z and m are as defined herein. A plurality of processes for preparing these compounds is provided, along with methods of using the compounds... | 04/06/2004 |
| 6706765 | Aminoguanidines and alkoxyguanidines as protease inhibitors Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR9 and R1-R4, R6-R9, R11, R12, Ra | 03/16/2004 |
| 6593315 | Salicylic acid derivatives, processes for their preparation, compositions comprising them, and their use Salicylic acid derivatives of the formula I, ##STR1## where the index and the substituents have the following meanings: X is halogen, NO2, cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to be different from each ... | 07/15/2003 |
| 6548539 | Agents for regulation of colon cancer gene expression Compounds of the general structure according to Formula (I) ##STR1## wherein R1 is selected from alkyl, alkenyl, alkynyl, heteroalkyl, haloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl, and heterocycloalkyl; R2 is s... | 04/15/2003 |
| 6518310 | Aminoguanidines and alkoxyguanidines as protease inhibitors Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: ##STR1## wherein X is O or NR9 and R1 -R4, R6 -R9, R11, R12, Ra, Rb, R | 02/11/2003 |
| 6506937 | Substituted benzenesulfonylureas and -thioureas-processes for their preparation and their use as pharmaceuticals Benzenesulfonylureas and -thioureas of the formula I ##STR1## where R(1) is H or (fluoro)methyl, R(2) is H, Hal or (fluoro) (mercapto)alk(oxy)yl, E is O or S; Y is --[CR(3)2 ]n --, where R(3)=H or alkyl and n=1-4, X is H, Hal or alky... | 01/14/2003 |
| 6410749 | Process for the preparation of optically active amino alcohols Process for preparing optically active ଲ-amino alcohols represented by a general formula (2): Ra--C*H(OH)--C*H(Rb)--Rc wherein Ra and Rc are each independently hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, Rb is one memb... | 06/25/2002 |
| 6323315 | Dolastatin peptides The present invention provides compounds of the formula ##STR1## where R1 -R5 are each, independently, a hydrogen atom or a normal or branched C1 -C6 -alkyl group; A is a methionyl, phenylalanyl or phenylglycyl ... | 11/27/2001 |
| 6252112 | Process for the preparation of an enantiomer of a (1R, 4S) or (1S, 4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene derivative A novel process for the preparation of (1S, 4R)- or (1R, 4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2 -cyclopentene-1-methanol of the formula ##STR1## is described.... | 06/26/2001 |
| 6242609 | Method for manufacturing a color coupler used in a silver halide photographic light-sensitive material A method for manufacturing a color coupler used in a silver halide photographic light-sensitive material using an ammonium trihalide. Said method for manufacturing the color coupler comprising the following step: a step for halogenating a coupling position of ... | 06/05/2001 |
| 6194612 | Template for solution phase synthesis of combination libraries This invention features a template for synthesizing combinatorial libraries, methods of synthesizing combiatorial libraries of chemical compounds utilizing the template, and combinatorial libraries of chemical compounds formed by the methods of this inven... | 02/27/2001 |
| 6090981 | Substituted benzenesulfonylureas and -thioureas--process for their preparation and their use as pharmaceuticals Benzenesulfonylureas and -thioureas of the formula I ##STR1## where R(1) is H or (fluoro)methyl, R(2) is H, Hal or (fluoro)(mercapto)alk(ozy)yl, E is O or S; Y is --[CR(3)2 ]n --, where R(3)=H or alkyl and n=1-4, X is H, Hal or ... | 07/18/2000 |
| 6057477 | Metal salt catalyzed process to oxazolines and subsequent formation of chloroketones This invention relates to a process for the preparation of an -chloroketone compound comprising the steps of (i) cyclizing an alkynyl amide to form a 5-methyleneoxazoline ##STR1## (ii) chlorinating the 5-methyleneoxazoline using trichlorolsocyanuri... | 05/02/2000 |
| 6054457 | Benzamide derivatives and their use as vasopressin antagonists This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc, and represented by general formula (I): ##STR1## wherein R1 is aryl optionally substituted with lower alkoxy, etc., R2 is lower... | 04/25/2000 |
| 5859063 | Use of certain N-acetonylbenzamides as fungicides Certain N-acetonylbenzamides exhibit low toxicity to plants are particularly useful for control of fungi, especially Phycomycetes.... | 01/12/1999 |
| 5821130 | Combinatorial dihydrobenzopyran library Combinatorial libraries are disclosed which are represented by Formula I: (T'--L)q --S--C(O)--L'--II' I wherein: S is a solid support; T'--L-- is an identifier residue; and --L'--II' is a ligand/linker residue. These libraries c... | 10/13/1998 |
| 5734063 | 4-acylaminophenylacetylenealcohol compounds The present invention provides a method for preparation of a compound of the formula (I) useful as a fog restrainer for a silver halide light-sensitive material, especially for a heat-developing light-sensitive material and a synthetic intermediate for th... | 03/31/1998 |
| 5637121 | Poly(oxyalkylene) aromatic amides and fuel compositions containing the same Poly(oxyalkylene) aromatic amides having the formula: ##STR1## or a fuel-soluble salt thereof; wherein a is hydroxy, nitro, amino, N-alkylamino wherein the alkyl group contains 1 to 6 carbon atoms, or N,N-dialkylamino wherein each alkyl group indepen... | 06/10/1997 |
| 5616726 | Optically active aminoalcohol derivatives and method of producing same An object of the present invention is to provide a safe method of commercially producing optically active aminoalcohol derivatives, which serve as intermediates for the synthesis of medicinal chemicals such as the immunopotentiating anticancer agent besta... | 04/01/1997 |
| 5609848 | Radiohalogenated small molecules for protein labeling Haloaryl compounds are lithiated and thereafter metalated with one of the following organometallic groups: Sn(n--Bu)3 or SnMe3. The resulting aryltin compound can be transmetalated in site-specific reaction with one of the following ... | 03/11/1997 |
| 5585373 | 3-(7'-oxo-1'-aza-4'-oxabicyclo[3.2.0]-hept-3'-YL)propionic acid derivative as antitumor agent A derivative of 3-(7'-oxo-1'-aza-4'-oxabicyclo[3.2.0 ]hept-3'-yl)propionic acid represented by the formula ##STR1## wherein R1 is a hydrogen atom, a lower alkyl group optionally having one or more cycloalkyl groups, a lower acyl group, a b... | 12/17/1996 |
| 5523463 | Method of producing halogenated and alpha-aminoalchohols A process for the manufacture of N-protected -aminoketones and N-protected -aminoalcohols of the formula ##STR1## wherein X is halogen, one of Q1 and Q2 is hydrogen and the other is hydroxy or Q1 and Q | 06/04/1996 |
| 5508435 | Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- or gamma-ketoamides ଲ- or γ-Ketoesters and ଲ- or γ-ketoamides are asymmetrically reduced with a Ru(II)-BINAP derived catalyst at about 40° C. and about 50N/mm2 of hydrogen in the presence of a strong acid.... | 04/16/1996 |
| 5457108 | 5-oxo-dibenzo[a,d]cyclohepta-1,4-dienes The invention relates to substituted 5-oxo-di-benzo[a,d]cyclohepta-1,4-dienes of the formula (I) ##STR1## processes for their preparation and their use as retroviral agents.... | 10/10/1995 |
| 5354905 | N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivative An N-alkoxymethyl benzamide derivative represented by Formula (I); ##STR1## (In the formula, reference X indicates a halogen atom, references Y1 and Y2 indicate hydrogen atoms or halogen atoms, and may be identical or different,... | 10/11/1994 |
| 5338884 | Method for the preparation of arylalkanolamineacylates Acylamides or amine acylate salts of arylalkanolamines are prepared by reacting an arylisonitrosoalkanone with hydrogen and a carboxylic acid, carboxylic acid anhydride or carboxylic acid ester or mixture thereof in the presence of a transition metal cata... | 08/16/1994 |
| 5304572 | N-acetonylbenzamides and their use as fungicides Novel N-acetonylbenzamides and their use in controlling phytopathogenic fungi.... | 04/19/1994 |
| 5298647 | Aromatic compounds of amide structure derived from aminobenzoic acids, hydroxy-benzoic acids, cinnamic acids, urocanic acids and benzimidazoles, absorbing UVB and/or UVA Aromatic compounds absorbing UVB and/or UVA, substituted with an amide function, selected from the group consisting of ##STR1## whose variable substituents are as defined in the specification, e.g. ##STR2## are useful as photoprotective agents o... | 03/29/1994 |
| 5296612 | Process for producing enyne derivatives A process for producing an enyne derivative, and intermediate, which is useful for preparing compounds showing strong inhibiting activities against squalane epoxidase of Eumycetes and strong anti-cholesterol activities. The process comprises reacting a co... | 03/22/1994 |
