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| Number | Title | Issue Date |
| 7371887 | Oligo(p-phenylene vinylene) amphiphiles and methods for self-assembly Amphiphilic oligo(p-phenylene vinylene) compounds and methods of use en route to self-assembled composites and device fabrication. ... | 05/13/2008 |
| 7348449 | Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof Novel ligand antagonists of the RAR receptors have the following structural formula (I): in which A is a CH2, CHOH, C═O or C═N—OH radical or a sulfur or selenium atom; B is a radical selected from among tho... | 03/25/2008 |
| 7195755 | Compositions comprising at least one hydroxide compound and at least one reducing agent, and methods for relaxing hair Compositions, optionally heat-activated, methods and kits for lanthionizing keratinous fibers to achieve relaxation of said keratinous fibers comprising applying to keratinous fibers a composition comprising at least one hydroxide compound and at least one reducing ... | 03/27/2007 |
| 7026510 | Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them (R)-Enantiomers of quaternary ammonium salts of general formula (I) are described: where R, R1, R2, R3, X and Z are as defined in the description. The process for their preparati... | 04/11/2006 |
| 6407120 | Neuropeptide Y antagonists The compound ##STR1## is a neuropeptide Y antagonist and is effective in treating feeding disorders, cardiovascular diseases and other physiological disorders.... | 06/18/2002 |
| 6288071 | 1-ethylene-2-alkylene-1,4-cyclohexadiene pesticides Pesticidally active cyclohexadienyl derivative compounds of the formula I that are esters, oximes or amides are claimed. These compounds may be used as fungicides, acaricides and insecticides in plant protection.... | 09/11/2001 |
| 6288122 | Gardos channel antagonists Novel inhibitors of potassium flux are disclosed. The inhibitors show surprising resistance to degradation in biological media and enhanced in vivo half-lives relative to non-fluorine substituted homologues. Methods for the use of these compounds include ... | 09/11/2001 |
| 6251917 | Benzamidoaldehydes and their use as cysteine protease inhibitors Compounds of the formula ##STR1## where R1, R2, R3, X and n are as defined in the description, are inhibitors of cysteine protease.... | 06/26/2001 |
| 6207716 | Non-steroidal ligands for the estrogen receptor Novel non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states.... | 03/27/2001 |
| 6172262 | Amphiphilic agents for membrane protein solubilization Disclosed are amphiphilic compounds comprising Formula I: ##STR1## wherein R1, R2, and R3 are C2 -C12 straight or branched alkyl; unsubstituted phenyl, biphenyl, C3 -C8 cycloalky... | 01/09/2001 |
| 6069247 | Process for preparing substituted acrylamides by reaction of propiolamides and aromatic rings The present invention relates to a process for preparing acrylamides; wherein, a propiolamide is reacted with an activated aromatic ring to yield a wide variety of acrylamides.... | 05/30/2000 |
| 6054457 | Benzamide derivatives and their use as vasopressin antagonists This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc, and represented by general formula (I): ##STR1## wherein R1 is aryl optionally substituted with lower alkoxy, etc., R2 is lower... | 04/25/2000 |
| 6005125 | Universal allyl linker for solid-phase nucleic acid synthesis A universal linker for solid-phase nucleic acid synthesis that is cleaved under conditions orthogonal to those used during the synthesis and deprotection of nucleic acids such as dsDNA or RNA fragments is disclosed. The invention includes compounds of the... | 12/21/1999 |
| 5965579 | Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharmaceutical compositions containing them The invention relates to compounds of the formula: ##STR1## Compounds of the above formula have a great affinity for the neurotensin receptors.... | 10/12/1999 |
| 5939449 | Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharmaceutical compositions containing them The invention relates to compounds of the formula: ##STR1## The compounds have great affinity for the neurotensin receptors.... | 08/17/1999 |
| 5922771 | Benzocycloalkene compounds, their production and use A compound of the formula ##STR1## wherein R1 and R2 independently represent H or an optionally substituted hydrocarbon group; R3 represents an optionally substituted hydrocarbon group; R4 represents H or a... | 07/13/1999 |
| 5877219 | Non-steroidal ligands for the estrogen receptor Described herein are non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states.... | 03/02/1999 |
| 5770736 | Reagents for cleavage or crosslinking of biomolecules using nondiffusible reactive intermediates Reagents for cleaving or crosslinking of biomolecules using nondiffusible reactive intermediates and a method of using the reagents. In one embodiment, the DNA binding element includes a phenyl group on each end, and each terminal phenyl group contains at... | 06/23/1998 |
| 5693630 | Phenylethyl and phenylpropylamines Compounds of the general formula ##STR1## or pharmaceutically acceptable salts thereof, wherein Z is a saturated or unsaturated 3 to 6 carbon chain, m is 2 or 3, R1 is a hydrogen atom, or a straight or branched C1-4 alkyl group,... | 12/02/1997 |
| 5686608 | Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates A process for preparing polycyclic aromatic compounds by cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates in the presence of metallic palladium as catalyst comprises adding to the reaction a) at least one... | 11/11/1997 |
| 5643950 | Triphenylalkyl antimicrobial agents The invention relates to triphenylalkyl antibacterial compounds of the general formula: ##STR1## pharmaceutical compositions containing the compounds, and methods for their production and use. These compounds are effective in inhibiting the acti... | 07/01/1997 |
| 5607931 | 1,2-disubstituted ethly amides as inhibitors of ACAT Amides of the formula ##STR1## wherein: R1 is A and R2 is B; R1 is B and R2 is A; or R1 and R2 are independently selected from the group B; A is phenyl, substituted phenyl, heteroaryl, or s... | 03/04/1997 |
| 5550236 | Process for cross-coupling aromatic boronic acids with aromatic halogen compounds or perfluoroalkylsulfonates A process for preparing polycyclic aromatic compounds by cross-coupling aromatic boronic acids with aromatic halogen compounds or perfluoroalkylsulfonates in the presence of metallic palladium, if desired applied to a support material, as catalyst, wherei... | 08/27/1996 |
| 5430060 | Acetamide derivatives The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, ... | 07/04/1995 |
| 5416118 | Bicyclic amides as inhibitors of acyl-coenzyme A: cholesterol acyl transferase Novel bicyclic amides of the formula ##STR1## wherein Ar1 and Ar2 are phenyl, R2 -substituted phenyl, heteroaryl or R2 -substituted heteroaryl, wherein R2 is 1 to 3 substituents independently sel... | 05/16/1995 |
| 5321031 | 1,2-disubstituted ethyl amides as inhibitors of ACAT Amides of the formula ##STR1## wherein: R1 is A and R2 is B; R1 is B and R2 is A; or R1 and R2 are independently selected from the group B; A is phenyl, substituted phenyl, heteroaryl, or s... | 06/14/1994 |
| 5270342 | Acetamide derivatives The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, ... | 12/14/1993 |
| 5208388 | 2,2-difluorocyclopropyl derivatives 2,2-Difluorocyclopropyl derivatives of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl and X represents hydroxymethyl, 2-hydroxyethyl, isocyanato, amino, amino hydrohalide or a radical o... | 05/04/1993 |
| 5202356 | Pesticidal cyclopropyl-2,4-dieneamides The present Application discloses pesticidally active compounds of the formula (I): Q Q1 CR2 =CR3 CR4 =CR5 C (.dbd.X) NHR1 or a salt thereof, wherein Q is an monocyclic aromatic ring. or fused b... | 04/13/1993 |
| 5186921 | Dopamine receptor ligands and image agents Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofur an, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain re... | 02/16/1993 |
| 5149709 | Inhibitors of acyl-coenzyme A: cholesterol acyl transferase Amides of the formula ##STR1## wherein R1 and R2 are independently heteroaryl, X-substituted heteroaryl, X-substituted phenyl, N-substituted triazinyl or N-substituted imidazolyl; and in addition, one of R1 and R... | 09/22/1992 |
| 5136081 | Process for the preparation of cyclopentene, cyclopentane and cyclohexane derivatives The invention provides a process for the preparation of fungicidally active cyclopentene derivatives of the general formula ##STR1## cyclopentane derivatives of the general formula ##STR2## and cyclohexane derivatives of the general formula ... | 08/04/1992 |
| 5122361 | Dopamine receptor ligands and imaging agents Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofur an, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain re... | 06/16/1992 |
| 5118697 | Cyclic beta-ketoamide ACAT inhibitors Novel cyclic beta-ketoamides which contain an aryl moiety having utility as blood cholesterol lowering agents rendering them useful in the treatment of atherosclerosis.... | 06/02/1992 |
| 5095147 | 2,2-difluorocyclopropyl derivatives 2,2-Difluorocyclopropyl derivatives of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl and X represents hydroxymethyl, 2-hydroxyethyl, isocyanato, amino, amino hydrohalide or a radical o... | 03/10/1992 |
| 5034418 | Diphenylethylene derivatives, pharmaceutical compositions containing same and treatment methods A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or... | 07/23/1991 |
| 4920222 | Preparation of 3,3-diarylacrylic acid amides 3,3-Diarylacrylic acid amides are prepared by the reaction of a benzophenone with an acetamide in the presence of a base characterized in that a sodium alcoholate is used as the base.... | 04/24/1990 |
| 4912217 | Preparation of 3,3-diphenylacrylic acid amides 3,3-diphenylacrylic acid amides are prepared by the reaction of a benzophenone with an acetamide in the presence of an alkali metal tertiary alcoholate characterized in that an alkali metal mono-alkyl carbonate is additionally present.... | 03/27/1990 |
| 4897397 | Aryl-alkynoic, alkenoic or alkanoic compounds and compositions useful as antiallergy and anti-inflammatory agents Certain aryl-alkynoic, alkenoic and alkanoic acids and derivatives and their use in treating inflammation, allergy and hyperproliferative skin disease are disclosed.... | 01/30/1990 |
| 4814483 | Process for the preparation of optionally substituted 2-benzyl-toluenes Optionally substituted 2-benzyl-toluenes can be prepared by reaction of optionally substituted 2-benzyl-tert.-alkyl-toluenes with an optionally substituted aromatic hydrocarbon in the presence of anhydrous iron-(III) halide. The reaction is carried out at... | 03/21/1989 |
