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Class 564/168 - Ring in a substituent E


Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the amino nitrogen containing residue
No. of patents: 168
Last issue date: 10/21/2008


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NumberTitleIssue Date
7439356Substituted indan derivatives
The present invention relates to intermediates of the formula useful in the preparation of piperazinyl-substituted indan derivatives, wherein Y is CONR2 wherein R2 is H or C1-C
10/21/2008
7374749Amino substituted hydroxyphenyl benzophenone derivatives
Described are amino substituted hydroxyphenyl benzophenone derivatives of formula (I), wherein R1, and R2 independently from each other are; C1-C20alkyl; C2-C20-alken...
05/20/2008
7345200Phase change ink formulations, colorant formulations, and methods of forming colorants
A compound having the formula wherein R1, Z, and the carbonyl can be comprised by a common ring, wherein R1 comprises a chromophore that absorbs light from the visible wavelength range, and wherein n i...
03/18/2008
7323595Phase change ink formulations, colorant formulations, and methods of forming colorants
A compound having the formula wherein R1, Z, and the carbonyl can be comprised by a common ring, wherein R1 comprises a chromophore that absorbs light from the visible wavelength range, and ...
01/29/2008
7147866UV-absorbing lipid vesicles
Highly effective vesicular compositions from UV-absorbing lipids are described in the present invention. Combination of UV-absorbing property and the vesicular delivery system results in higher levels of photoprotection to skin and hair. The vesicular compositions o...
12/12/2006
7122547Anthranilic acid amides and the use thereof as medicaments
The invention relates to anthranilic acid amides and the use thereof as medicaments for the treatment of diseases that are triggered by persistent angiogenesis, in addition to intermediate products in the production of anthranilic acid amides. ...
10/17/2006
7049271Phenyl-substituted 2-enamino-ketonitriles
The present invention relates to novel phenyl-substituted 2-enamino-ketonitriles of the formula (I): in which Ar, X, Z, Y and K are each as defined in the description, to a plurality of pro...
05/23/2006
7022879Phase change ink formulations, colorant formulations, and methods of forming colorants
The invention encompasses a compound having the formula: wherein R1, Z and the carbonyl can be comprised by a common ring, wherein R1 comprises a chromophore that absorbs light from the visible wav...
04/04/2006
6891066N-(4-substituted phenyl)-anthranilic acid hydroxamate esters
The present invention relates to oxygenated esters of 4-substituted-phenylamino benzhydroxamic acid derivatives, pharmaceutical compositions and methods of use thereof. ...
05/10/2005
6852761Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
The invention relates to polycyclic aryl and heteroaryl substituted benzene compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety ...
02/08/2005
6803383Inhibition of angiogenesis and tumor growth
Compounds which inhibit tumor growth and angiogenesis, of general formula (II) are provided. These compounds include glycyl lysine derivatives bound to a central aromatic linking core. ...
10/12/2004
6720452Adamantane derivatives
The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therap...
04/13/2004
6706765Aminoguanidines and alkoxyguanidines as protease inhibitors
Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR9 and R1-R4, R6-R9, R11, R12, Ra
03/16/2004
6683201Analine derivatives as OSC inhibitors
The present invention relates to compounds of formula (I) ##STR1## wherein U, Y, V, W, L, X, A1, A2, A3, A4, A5 and A6 are as defined in the description and claims and pharmaceutically acce...
01/27/2004
6660885Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
The invention relates to polycyclic aryl and heteroaryl substituted benzene compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of...
12/09/2003
6653309Inhibitors of IMPDH enzyme technical field of the invention
The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for inhibit...
11/25/2003
6638942Spiro-indolines as Y5 receptor antagonists
Compounds of general structural formula I ##STR1## are selective NPY Y5 receptor antagonists, useful in the treatment of obesity and the complications associated therewith....
10/28/2003
6624184Amide and diamide inhibitors of IMPDH enzyme for use in treating IMPDH-associated disorders
The present invention discloses the identification of the inhibitors of IMPDH (inosine-5'-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as...
09/23/2003
6610701Thrombin inhibitors
Compounds of the invention are useful in inhibiting thrombin and treating blood coagulation and cardiovascular disorders and have the following structure: ##STR1## wherein R3 is hydrogen or halogen, and u is N or CH....
08/26/2003
6545054Alkenyl and alkynyl compounds as inhibitors of factor Xa
Alkenyl and alkynyl compounds as potent and highly selective inhibitors of factor Xa isolated or assembled in the prothrombinase complex and compositions containing such alkenyl and alkynyl compounds are described. Such compounds show selectivity for fact...
04/08/2003
6521603Fungicides for the control of take-all disease of plants
A method of controlling Take-all disease of plants, by applying, preferably to the seeds prior to planting, a fungicide of the formula ##STR1## wherein Z1, and Z2 are C and are part of an aromatic ring which is benzene....
02/18/2003
6518310Aminoguanidines and alkoxyguanidines as protease inhibitors
Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: ##STR1## wherein X is O or NR9 and R1 -R4, R6 -R9, R11, R12, Ra, Rb, R
02/11/2003
6495693N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting ଲ-amyloid peptide release and/or its synthesis by use of such compounds
Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid...
12/17/2002
6489511Azomethine compound manufacture
Disclosed is a process for forming an azomethine compound, comprising: (a) reacting a compound "A" having an active methylene group or methine group with an arylprimaryamine compound "B"; (b) in the presence of a base and an oxidizing agent and in a solvent me...
12/03/2002
6458781Substituted diarylalkyl amides as calcium channel antagonists
The present invention provides compounds that block calcium channels and have the Formula I: ##STR1## The present invention also provides pharmaceutical compositions containing the compounds of Formula I and methods of using them to treat stroke, cer...
10/01/2002
6441043Glyoxylic acid amides
The invention relates to novel glyoxylic acid amides, to a plurality of processes for their preparation and to their use for controlliing pests....
08/27/2002
6441231Optically active quarternary ammonium salt with axial chirality, method for producing thereof, and application thereof for asymmetric synthesis of ଱-amino acid
A novel optically active quarternary ammonium salt with an axial chirality is provided. The quarternary ammonium salt can act as a phase-transfer catalyst to convert glycine derivatives into optically active ଱-amino acid derivatives by stereoselecti...
08/27/2002
6372885Solid-phase technology for the preparation of amides
Method for preparing a combinatorial chemistry library of compounds of the formula R1--C(.dbd.O)--NH--R2, wherein R1 and R2 are as defined in the specification, which comprises acylating a combinatorial chemistry intermediate of the formula 1A ##STR1...
04/16/2002
6355666Protected forms of pharmacologically active agents and uses therefor
In accordance with the present invention, there are provided normal modified forms of nonsteroidal anti-inflammatory drugs. Modified NSAIDs according to the invention provide a new class of anti-inflammatory agent which provide the therapeutic benefits of...
03/12/2002
6326510Bi-aromatic compounds, compositions containing them and uses
The invention relates to novel biaromatic compounds having general formula I ##STR1## and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovasc...
12/04/2001
6313166Phenyl acetic acid derivatives as pesticides
Compounds of the formula I ##STR1## and the isomers thereof, in which either a) X is an N atom and Y is OR11 or N(R12)R13, or b) X is CH and Y is OR11, and in which furthermore: R11 is C1 -C4
11/06/2001
6262302N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting ଲ-amyloid peptide release and/or its synthesis by use of such compounds
Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid pep...
07/17/2001
6255496Trifluoromethyl ketone analogs as selective cPLA2 inhibitors
Selective inhibitors of the cPLA2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula ##STR1##...
07/03/2001
6251917Benzamidoaldehydes and their use as cysteine protease inhibitors
Compounds of the formula ##STR1## where R1, R2, R3, X and n are as defined in the description, are inhibitors of cysteine protease....
06/26/2001
6248781Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
The present invention relates to compounds of formula (I) ##STR1## wherein R1, R2, R3, R4, R5, R6, R7, R8, Ar, X, Q, A, Y and Z are as defined in the specification. These ...
06/19/2001
6194612Template for solution phase synthesis of combination libraries
This invention features a template for synthesizing combinatorial libraries, methods of synthesizing combiatorial libraries of chemical compounds utilizing the template, and combinatorial libraries of chemical compounds formed by the methods of this inven...
02/27/2001
6194418Substituted aminosalicyclic acid amides with fungicidal effect and intermediate products for production thereof
The invention relates to novel substituted aminosalicylamides, to a plurality of processes for their preparation and to their use as fungicides, and also to novel intermediates and to a plurality of processes for their preparation....
02/27/2001
6153652N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting ଲ-amyloid peptide release and/or its synthesis by use of such compounds
Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid pep...
11/28/2000
6096924Process for the catalytic hydrogeneration of aromatic nitro compounds
One object of the invention is a process for the catalytic hydrogenation of aromatic nitro compounds in solution or in melt in the presence of hydrogen and at least one noble metal catalyst, nickel catalyst or cobalt catalyst, in which process a catalytic...
08/01/2000
6066672Amino compounds and angiotensin IV receptor agonists
The present invention provides an amino compound represented by Formula: ##STR1## wherein X is CH2 NH or CONH, Y is CH2 NH or CONH with the proviso that X and Y are not CONH at the same time; Z is CH.dbd.C(R4)R5
05/23/2000
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