"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 7250446 | Mercaptophenyl naphthyl methane compounds and synthesis thereof Novel mercaptophenyl naphthyl methane compounds, their pharmaceutically acceptable salts and compositions comprised thereof are useful for the prevention or treatment of various medical indications associated with estrogen dependent diseases or syndromes related to ... | 07/31/2007 |
| 7145035 | Methods of ortho alkylation The present invention pertains to methods for preparing a compound of Formula (I), wherein A is O or N-L; each L is independently H or an acyl group; K is, together with the two contiguous linking carbon atoms, a phenyl ring, a 5- or 6-membered heteroaromatic ring o... | 12/05/2006 |
| 7132294 | Functionalized small molecules for use in chemical sensors The invention provides a device for selective molecular recognition, the device comprising a sensing portion, wherein said sensing portion includes a substrate having coated thereon a layer comprising a non-volatile, small molecule compound having at least two penda... | 11/07/2006 |
| 6479550 | -sulfenimino acid derivatives -Sulfenimino acid derivatives of formula I ##STR1## including the optical isomers thereof and mixtures of such isomers, wherein A is cycloalkyl, cycloalkenyl, aryl or heteroaryl, each optionally substituted, B is a direct bond or optionally substituted ... | 11/12/2002 |
| 6387954 | Alkenyl sulphonamide derivatives The present invention provides certain alkenyl sulphonamide derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.... | 05/14/2002 |
| 6350545 | Sulfonylimide compounds Novel sulfonylinide and sulfonylmethide compounds are described which are useful as conductive salts. Also described is the use of the above compounds in salt form in battery electrolytes, particular salts having mixed perfluorocaron and hydrocarbon group... | 02/26/2002 |
| 6326393 | Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases Compounds of Formula I ##STR1## are disclosed as inhibitors having activity against the aspartyl proteases, plasmepsin and cathepsin D. The compounds are therefore useful for treatment of diseases such as malaria and Alzheimer's disease. In preferred... | 12/04/2001 |
| 6288231 | Peptide-containing -ketoamide cysteine and serine protease inhibitors This invention relates to peptide-containing -ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.... | 09/11/2001 |
| 6242645 | Thermally stable aminosulfur trifluorides Diaryl-, dialkoxyalkyl-, alkylalkoxyalkyl-, arylalkoxyalkyl- and cyclic aminosulfur trifluorides fluorinating agents are disclosed.... | 06/05/2001 |
| 6242609 | Method for manufacturing a color coupler used in a silver halide photographic light-sensitive material A method for manufacturing a color coupler used in a silver halide photographic light-sensitive material using an ammonium trihalide. Said method for manufacturing the color coupler comprising the following step: a step for halogenating a coupling position of ... | 06/05/2001 |
| 6222064 | Fluorination with aminosulfur trifluorides A fluorination method of oxygen and halogen sites with diaryl-, dialkoxyalkyl-, alkylalkoxyalkyl-, arylalkoxyalkyl- and cyclic aminosulfur trifluorides fluorinating reagents is disclosed.... | 04/24/2001 |
| 6207860 | Thermally stable aminosulfur trifluorides Diaryl-, dialkoxyalkyl-, alkylalkoxyalkyl-, arylalkoxyalkyl- and cyclic aminosulfur trifluorides fluorinating agents are disclosed.... | 03/27/2001 |
| 6194463 | N-sulphonyl and N-sulphinyl amino acid amides as microbicides -Amino acid amides of formula (I) wherein the substituents are defined as follows: n is a number zero or one; R1 to R7 are as defined herein; R8 is C1 -C6 alkyl, C3 -C6 al... | 02/27/2001 |
| 6184385 | Process for the manufacture of a sulfenimide A process for the manufacture of a sulfenimide by reacting sulfenamide in slurry with a water immiscible organic solvent with an acid to yield a solvent slurry comprising sulfenimide product. The product is recovered from the solvent slurry by a method co... | 02/06/2001 |
| 6114580 | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds N-arylsulfilimine compounds, such as S,S-dimethyl-N-(2,6-dichlorophenyl)sulfilimine, were prepared and found to catalyze the reaction of aromatic sulfonyl chloride compounds, such as 2-chlorosulfonyl-7-fluoro-5-ethoxy[1,2,4]triazolo[1,5-c]pyrimidine, with... | 09/05/2000 |
| 6080886 | Fluorination with aminosulfur trifluorides A fluorination method of oxygen and halogen sites with diaryl-, dialkoxyalkyl-, alkylalkoxyalkyl-, arylalkoxyalkyl- and cyclic aminosulfur trifluorides fluorinating reagents is disclosed.... | 06/27/2000 |
| 5973148 | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds N-arylsulfilimine compounds, such as S,S-dimethyl-N-(2,6-dichlorophenyl)sulfilimine, were prepared and found to catalyze the reaction of aromatic sulfonyl chloride compounds, such as 2-chlorosulfonyl-7-fluoro-5-ethoxy[1,2,4]triazolo[1,5-c]pyrimidine, with... | 10/26/1999 |
| 5962531 | 5-aroylnaphthalene derivatives as anti-inflammatory agents The present invention relates to certain 5-aroylnaphthalene derivatives of formula (I): ##STR1## that are inhibitors of prostaglandin G/H synthase, pharmaceutical compositions containing them, methods for their use, and methods for preparing the... | 10/05/1999 |
| 5708034 | Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them Sulfonimidamides of the formula I ##STR1## in which at least one of the three substituents R(1), R(2) and R(3) is a ... | 01/13/1998 |
| 5514826 | Vinyl sulfenic acid derivatives The present invention is directed to novel vinyl sulfenic acid derivatives, useful for the synthesis of benzo b!thiophenes, in particular 2-arylbenzo b!thiophenes.... | 05/07/1996 |
| 5512701 | Process for the synthesis of vinyl sulfenic acid derivatives The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo b!thiophenes, in particular 2-aryl-benzo b!thiophenes.... | 04/30/1996 |
| 5403853 | Substituted N-aryl-1,2-diaminocyclobutene-3,4-diones The compounds of the formula: ##STR1## wherein R1 and R2 are, independently, hydrogen, straight or branched chain alkyl or mono- or bi-cyclic alkyl; A is a substituted phenyl group containing one or two substituents selected fro... | 04/04/1995 |
| 5324857 | Inhibition of the formation of nitrosamines Reaction of amine-containing substrates with hydrogen peroxide can suffer from certain problems, especially in the presence of transition metals. These problems include both in situ generation of impurities and particularly nitrosamines, which are alleged... | 06/28/1994 |
| 5227401 | Ethynyl alanine amino diol compounds for treatment of hypertension Compounds characterized generally as ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I ##STR1## wherein A is selected from CO and SO2 | 07/13/1993 |
| 5223535 | Propargyl glycine amino propargyl diol compounds for treatment of hypertension Compounds characterized generally as propargyl glycine amino propargyl diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I ##STR1## wherein A is selected from CO a... | 06/29/1993 |
| 5124348 | Pesticidal amides A compound of Formula (I): R1 (CA.dbd.CA1)x --C(.dbd.X)NR2 R3 (I) where R1 is alkyl optionally substituted by a group selected from alkoxy, alkenyl, alkynyl, alkenyloxy, alkynyloxy, aryl, aryloxy, ... | 06/23/1992 |
| 5112868 | Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition The present invention is novel selected hydroxamic acid derivatives of acyl residues of selected NSAIDS, i.e. having 5-lipoxygenase and cyclooxygenase inhibiting properties, pharmaceutical compositions for treating conditions advantageously affected by th... | 05/12/1992 |
| 5110989 | Herbicidal compounds and compositions The invention concerns novel compounds of the formula I ##STR1## wherein: W are selected from alkyl, alkenyl and alkynyl; X are selected from halogen, nitro, cyano, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, alkenyl, alkynyl, alkenylox... | 05/05/1992 |
| 5081284 | Proteinase inhibitor A novel N-substituted peptidyl compound represented by the general formula (1): ##STR1## where R1 is a straight-chained or branched acyl group having 2-10 carbon atoms, a branched, cyclic or partly branched cyclic alkyloxycarbonyl gro... | 01/14/1992 |
| 5055582 | Process for preparing thromboxane A2 antagonists This invention relates to a process for preparing useful thromboxane A2 inhibiting (b1;)7-[3-[1-[[(phenylamino)thioxomethyl]hydrazono]ethyl]-1 ,4-bicyclo[2.2.1]hept-2ଲ-yl]-heptenoic acids and useful derivatives ... | 10/08/1991 |
| 5047158 | Olefinic hydrocarbon modification with sulfur imides Hydrocarbon compositions, including oligomers and polymers, for use in improving the thermo-oxidative stability and the dispersancy and viscosity index improvement (for high molecular weight) properties of fuels and lubricating oils are disclosed. These c... | 09/10/1991 |
| 5023376 | Reduction of nitrosamine formation Reaction of amine-containing substrates with hydrogen peroxide can suffer from the problems of in situ generation of nitrosamines, which are allegedly carcinogens, as impurities and impaired product formation, especially in the presence of transition meta... | 06/11/1991 |
| 4964846 | Process for the E/Z stereoselective synthesis of homochiral five and six ring intermediate products This invention comprises a process for the production of unsymmetrical olefins from prochiral symmetrical ketones by addition of lithiosulfoximine from n-butyllithium and N-substituted S-methyl-S-phenyl-sulfoximine derivatives and then reaction with ... | 10/23/1990 |
| 4946992 | Heteroatom containing perfluoroalkyl terminated neopentyl glycols and compositions therefrom Heteroatom containing perfluoroalkyl terminated neopentyl glycols of the formulas HO[--CH2 C(CH2 X--E--Rf)2 CH2 O]1-3 --H or HO[--CH2 C(CH2 X--Rf)2 CH... | 08/07/1990 |
| 4777292 | Preparation of ortho-methyl anilines from ortho-amino benzyl sulfoxides This invention relates, in one of its aspects, to a process for the preparation of ortho-methyl anilines from ortho-amino benzyl sulfoxides. An ortho-amino benzyl sulfoxide is converted to an ortho-amino benzyl halide by reaction with a nonoxidizing acid ... | 10/11/1988 |
| 4772406 | Olefinic hydrocarbon modification with sulfur imides Hydrocarbon compositions, including oligomers and polymers, for use in improving the thermo-oxidative stability and the dispersancy and viscosity index improvement (for high molecular weight) properties of fuels and lubricating oils are disclosed. These c... | 09/20/1988 |
| 4628094 | Tris(disubstituted amino)sulfonium perfluoroalkoxides and perfluoroalkylmercaptides and process for their preparation Tris(disubstituted amino)sulfonium perfluoroalkoxides and tris(disubstituted amino)sulfonium perfluoroalkylmercaptides and process for their preparation.... | 12/09/1986 |
| 4626597 | 16-fluoro-16,17-didehydro prostanoids and process for their preparation 16-Fluoro-16,17-didehydro prostanoids, processes for their preparation, compositions containing them and methods of using them are disclosed. The compounds and compositions have pharmaceutical utility including, for example, luteolytic activity.... | 12/02/1986 |
| 4606862 | Amides of N-(3-(1-chloro-2-nitroethenylthio)propane) A process for preparing insecticidal N-acyl-tetrahydro-2-nitromethylene-2H-1,3-thiazines, intermediates involved therein and certain of the products.... | 08/19/1986 |
| 4596811 | Heterocyclic compounds, a process for their production and medicaments containing these compounds The invention relates to special heterocyclic compounds corresponding to general tautomeric formula I which are distinguished by improved antagonistic activity on histamine-H2 -receptors. The invention also relates to a process for producing th... | 06/24/1986 |