Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 4064138 | Amino acid derivatives Disclosed are amino acid derivatives including amino acid fluoride phosphates and alkali metal amino acid fluoride phosphates.... | 12/20/1977 |
| 4061542 | 2-Methyl-L-arginine produced by cultivating streptomyces strain The compound 2-methyl-L-arginine having useful antibiotic and anti-bacterial properties and its methods of preparation from a new species of Streptomyces sp. X-11837 or from 5-hydroxy-2-pentanone.... | 12/06/1977 |
| 4058558 | Aromatic keto acids and derivatives having analgetic, antiinflammatory, and hypocholesterolemizing action This invention relates to new chemical compounds useful as drugs, as well as to pharmaceutical compositions containing the same. The new products are aromatic keto acid compounds with antiinflammatory as well as analgetic and hypocholesteremic activity and hav... | 11/15/1977 |
| 4054588 | Process for the preparation in a single stage of saturated omega-aminoacids from olefinically unsaturated omega-aldehydoacids The specification describes a process for preparing saturated omega-aminods from olefinically unsaturated omega-aldehydoacids. According to the invention, the starting aldehydoacid is transformed into the corresponding iminoacid, and this is subjected to... | 10/18/1977 |
| 4052194 | Oxime abscission agents A method of aiding in harvesting fruit wherein abscission is induced by application to the fruit bearing plant of an effective amount of a compound of the formula ##STR1## or a salt thereof, wherein R1 is hydrogen, halogen, alkyl, alkenyl,... | 10/04/1977 |
| 4032676 | N-polyhydroxyalkyl-amino acids, their manufacture and skin treating agents containing the same The present invention relates to N-polyhydroxyalkyl-amino acids of the formula ##STR1## wherein R1 represents a phenylene or a group of the general formula --CHR3 --, wherein R3 represents hydrogen, alkyl, benzyl ... | 06/28/1977 |
| 4031064 | Aminoplast curing agents Maleamic and fumaramic acids and certain of their derivatives make very good curing agents for converting aminoplast condensates to cured resins.... | 06/21/1977 |
| 4028401 | (Substituted)ureidoacetohydroxamic acids A series of (substituted)ureidoacetohydroxamic acids are useful as inhibitors of Angiotensin I converting enzyme.... | 06/07/1977 |
| 4007222 | Process for the production of 2-chlorocaproic acids 2-Chloro-n-caproic acid and 6-substituted 2-chloro-n-caproic acids are produced from n-caproic acid or 6-substituted n-caproic acids are chlorinated in the presence of sulfur halides and phosphorus halides at elevated temperatures using for each mole of c... | 02/08/1977 |
| 3998861 | Preparation of omega-carboxyalkanohydroxamic acids A method of preparing omega-carboxyalkanohydroxamic acids is provided by contacting an ammonium, Group IA or Group IIA metal salt of a nitrocycloalkanone with an acidic mineral acid salt in a carboxylic acid solvent.... | 12/21/1976 |
| 3994965 | D-N-(guanylureidoacetyl)--aminophenyl acetic acid and D-N-(guanylureidoacetyl)--aminophenyl acetyl chloride Method of producing N-(guanylureidoacetyl)--aminophenylacetic acid and the utility thereof in the production of N-(guanylureidoacetyl)--aminophenylacetyl chloride and the utility of the latter compound for producing the title penicillanic ac... | 11/30/1976 |
| 3991112 | Methylated muconic acid hydrazides Mono and dihydrazides of the cis-cis, cis-trans and trans-trans isomers of methylated muconic acids including -methylmuconic acid, ଲ-methylmuconic acid, ,'-dimethylmuconic acid, ,ଲ'-dimethylmuconic acid, ³... | 11/09/1976 |
| 3989749 | 11,12-Secoprostaglandins This invention relates to 8,10-diaza-9-oxo(and thioxo)-11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, and for the prevention of ... | 11/02/1976 |
| 3972921 | Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts The racemates of 2-deutero-3-fluoro-alanine and its salts are prepared by reductive amination of 3-fluoro-pyruvic acid, its hydrate or salts thereof, via the intermediate 2-imino-3-fluoro propionic acid salt, using alkali metal borodeuterides as reducing ... | 08/03/1976 |
| 3962319 | -Hydroxy-ଲ-aminocarboxylic acids New -hydroxy-ଲ-aminocarboxylic acids which are agents for masking metal ions and auxiliaries for the paper and textile industries. Other outlets are in the textile industry in dyeing and bleaching, in metal refining, in the foodstuffs industr... | 06/08/1976 |
| 3962317 | D-3,6-Diaminohexanoic acid 2-(carboxymethyl)-2-methylhydrazide, process of preparing and intermediates of said process This disclosure describes D-3,6-diaminohexanoic acid 2-(carboxymethyl)-2-methylhydrazide which is useful as an antibacterial agent.... | 06/08/1976 |
| 3954816 | Photosensitive material comprising polyacetylenic amine salts Amine salts of polyacetylenic compounds containing a carboxylate moiety, preferably in conjunction with a group capable of hydrogen bonding, have unusually high radiation sensitivity, and are useful radiation-sensitive components in imaging systems.... | 05/04/1976 |
| 3943253 | Guanido acids as fungicides Compounds of the formula ##EQU1## wherein R is Cn H2n and wherein n is an integer of 1 to 11, and wherein Y is the sulfonic acid (--SO3 H) group or carboxylic acid (--CO2 H) group, have been found to have f... | 03/09/1976 |
| 3941775 | 6-Aza-3H-1,4-benzodiazepines There are produced 6-aza-3H-1,4-benzodiazepines and 6-aza-1,2-dihydro-3H-1,4-benzodiazepines of the formula: ##SPC1## Wherein R1 is the group --NRa Rb, --NRa Rb Rc or --NRa acyl ... | 03/02/1976 |
| 3941777 | Compounds having juvenile hormone activity This invention is concerned with certain alkyl, terpenoid and olefinic oximethers of some aryl, pyridyl and alifatie aldehydes and ketones, and their preparation and use. These compounds possess improved juvenile hormonal activity which can be utilized fi... | 03/02/1976 |
| 3935266 | N-substituted guanidino acid derivatives An N-substituted guanidino acid derivatives having the following formula of ##EQU1## wherein R is an alkyl having 6 to 15 carbon atoms,. a cycloalkyl having 6 to 15 carbon atoms or an aryl(C6 to C8)alkyl(C1 to C9... | 01/27/1976 |
