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| Number | Title | Issue Date |
| 7893298 | Method for concentrating an aqueous ammonium carbamate stream The invention relates to a method for concentrating an aqueous ammonium carbamate stream, which has been formed in a process for the preparation of urea, has a pressure between 0.20 MPa and 0.9 MPa, a temperature between 35° C. and 95° C., and contains at least 25... | 02/22/2011 |
| 7238834 | Piperidine derivatives and process for their production The present invention relates to substantially pure piperidine derivative compounds of the formulae: wherein R1 is hydrogen or hydroxy; R2 | 07/03/2007 |
| 7060851 | Method of preparing retroviral protease inhibitor intermediates Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtai... | 06/13/2006 |
| 7019003 | Peptide deformylase inhibitors Novel PDF inhibitors and novel methods for their use are provided. ... | 03/28/2006 |
| 6914157 | Method for obtaining an ammonium carbamate solution from a gas mixture containing NH3, H2O and CO2 The invention relates to a method for obtaining an ammonium carbamate solution from a gas mixture that contains more than 40 wt. % NH3, less than 50 wt. % CO2 and less than 40 wt. % H2O and has a pressure between 0.1 MPa and 4 MPa, c... | 07/05/2005 |
| 6903232 | Process for the preparation of a highly pure pharmaceutical intermediate, 4-(cyclopropylcarbonyl)-α, α-dimethylphenylacetic acid This invention relates to a novel process to obtain highly pure 4-(cyclopropylcarbonyl)-α,α-dimethylphenylacetic acid of Formula I through crystallization from a mixture of para and meta regioisomers of Formula I and II in cyclohexane, whereby the amount of undesi... | 06/07/2005 |
| 6806384 | Production method of β-amino-α-hydroxycarboxylic acid The present invention provides a production method of an optically active β-amino-α-hydroxycarboxylic acid, which includes the following steps (a)-(c): (a) treating an optically active N-carbamate protected β-amino epoxide with ... | 10/19/2004 |
| 6803378 | HIV integrase inhibitors Novel diketoacid compounds of Formula I are provided which are useful as HIV integrase inhibitors and for the treatment of AIDS or ARC. ... | 10/12/2004 |
| 6703498 | Water-soluble polymeric metal ion affinity compositions and methods for using the same Water-soluble metal ion affinity compounds and methods for using the same are provided. The subject compounds include an aspartate based metal chelating ligand bonded to a water-soluble polymeric substrate, where the ligand is complexed with a metal ion. ... | 03/09/2004 |
| 6686494 | Synthesis of S-alkyl and S-aryl thiocarbamates, one-pot two-step general synthesis A method for preparing S-alkyl and S-aryl thiocarbamates comprising reacting a precursor thiol reagent with trichloroacetyl chloride to produce an S-alkyl and S-aryl trichloroacetyl thioester intermediate, which is reacted with an amine to yield the corre... | 02/03/2004 |
| 6399809 | Process for the preparation of amino acid derivatives Process for the preparation of amino acid derivatives of the general formula I ##STR1## where R1 -R4 are as defined herein, from the corresponding malonic acid monoester amides of the general formula II ##STR2## by Hofmann degr... | 06/04/2002 |
| 6207868 | Asymmetric synthesis catalyzed by transition metal complexes with chiral ligands This invention is to develop novel transition metal catalysts for the practical synthesis of important chiral molecules. The invention emphasizes asymmetric catalysis based on chiral bidentate phosphine ligands with cyclic ring structures which could be u... | 03/27/2001 |
| 6063955 | Method for producing optically active erythro-3-amino-2-hydroxybutyric esters and acids thereof A method for producing an optically active erythro-3-amino-2-hydroxybutyric ester as an important intermediate of pharmaceutical agents, specifically HIV protease inhibitor, in high purity and in high yield. The method includes producing an optically acti... | 05/16/2000 |
| 6034271 | Betaine gemini surfactants made from amines Amphiphilic amphoteric compounds of formula (I) ##STR1## wherein R1, R2, R3, R4, R5, and n are as defined in the disclosure.... | 03/07/2000 |
| 6007865 | Reversing the formation of advanced glycosylation endproducts The present invention relates to compositions and methods for inhibiting and reversing nonenzymatic cross-linking (protein aging). Accordingly, compositions are disclosed which comprise an agent capable of inhibiting the formation of advanced glycosylatio... | 12/28/1999 |
| 5990170 | Therapeutic use of mono and bicarboxylic acid amides active at the peripheral cannabinoid receptor The following description concerns a therapeutic method for the treatment of diseases connected with the modulation of the cannabinoid peripheral receptor, comprising administering amidic derivatives of mono and bicarboxylic acids with aminoalcohols or ar... | 11/23/1999 |
| 5981797 | Preparation of diamine carbamates Diamine carbamates are prepared by spraying liquid diamine into carbon dioxide gas, in the optional presence of a propellant.... | 11/09/1999 |
| 5932595 | Matrix metalloprotease inhibitors The present invention relates to compounds of Formula I: ##STR1## that are matrix metalloprotease inhibitors, pharmaceutical compositions containing them, methods for their use and methods of preparing these compounds.... | 08/03/1999 |
| 5932616 | Potent inducers of terminal differentiation and methods of use thereof The present invention provides the compound having the structure: ##STR1## wherein each of R1 and R2 are independently the same as or different from each other; when R1 and R2 are the same, each is a substi... | 08/03/1999 |
| 5905127 | Polymerizable mesophases based on substituted unsaturated carboxylic acids Mesogens are provided based on substituted unsaturated carboxylic acids such as acrylic and methacrylic acid. Substitution of a variety of hydrophobic tails onto the carboxylic acid or acid derivative via the vinyl carbon proximal to the carbonyl of the c... | 05/18/1999 |
| 5840972 | Process for preparing NG -monoalkyl-L-arginine and related compounds A process is disclosed for the preparation of NG -monoalkyl-L-arginine and related compounds and salts thereof, for example NG -monomethyl-L-arginine by reacting N-alkylaminoiminomethane sulphonic acid of formula (II) with an amino a... | 11/24/1998 |
| 5773465 | Tartronic acids, their acetalic ethers and o-esters Tartronic acid acetalic ethers and esters of the general formula: ##STR1## are provided and are useful in treatment of bone dysmetabolism. As examples, Ra and Rb may be hydrogen, B is a C2 -C12 acyl group, R is phenyl and n is 0... | 06/30/1998 |
| 5614503 | Amphipathic nucleic acid transporter A nucleic acid transporter to deliver a nucleic acids into cells, comprising a cationic compound having a cationic head group for binding the nucleic acid and a lipid tail for association with the membrane. A cationic compound usually is a polyamine or a ... | 03/25/1997 |
| 5581011 | Aromatic ketones and processes for their preparation The present invention relates to substantially pure piperidine derivative compounds of the formulae: ##STR1## wherein R1 is hydrogen or hydroxy; R2 is hydrogen; or R2 and R2 taken together form a second bond bet... | 12/03/1996 |
| 5571940 | Method for making conjugate moieties capable of chelating paramagnetic metals and designed for coupling with a factor responsive to specific cellular marker sites In this method, one attaches one or more chelatant molecules to a mono- or polyamino intermediate compound I which is temporarily immobilized on a solid phase by a splittable bond. Thereafter, said bond is split to release the desired conjugate moiety, wh... | 11/05/1996 |
| 5442088 | Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process L-amino acids of the formula I and salts thereof, ##STR1## in which R1 to R5 are defined as in claim 1 and n is ... | 08/15/1995 |
| 5414017 | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same Compounds of the formula ##STR1## wherein m is zero or 1; n is zero, 1 or 2; p is zero or 1 to 6 provided that m and p are not both zero; R3 is hydrogen, acyl, or benzyl; and R1 is hydrogen, alkyl, phenyl, substituted phenyl, ph... | 05/09/1995 |
| 5298655 | Farnesyl pyrophosphate analogs The present invention is directed to farnesyl pyrophosphate analogs which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the com... | 03/29/1994 |
| 5275752 | Method and product for inhibiting corrosion due to chlorides The corrosive effect of salt on reinforced concrete in roadways, overpasses, bridges and buildings is inhibited by the application of a composition which consists essentially of ammonium carbamate, or which consists essentially of ammonium carbamate combi... | 01/04/1994 |
| 5254611 | Water dispersable urethane acrylate oligomer Urethane oligomers having the formula: H2 C:CHCOORO[[COHNR'NHCO[O[CH2 ]t CCH3 X]m O]n [CONHR'NHCOYR"Y]p ]q CONHR'NHCOOROCOCH:CH2(I) as well as process therefor are de... | 10/19/1993 |
| 5247121 | Alkyl esters of n-carboalkyloxy amino-11-undecanoic acids, their processes of preparation and their use as thickening agents The alkyl esters of N-carboalkyloxy-11-aminoundecanoic acids have the following general formula: ##STR1## wherein R is linear or branched C7-30 alkyl, linear or branched C4-22 alkenyl or a radical of formula: ##STR2## ... | 09/21/1993 |
| 5219644 | Treated polymer fabrics This invention relates to an article comprising: (A) at least one polymer fabric treated with (B) at least one wetting agent which comprises at least one compound of the formulae ##STR1## wherein each R1 is independently a hydrocarbyl group ha... | 06/15/1993 |
| 5209966 | Treated polymer fabrics This invention relates to an article comprising: (A) a polymer fabric treated with (B) a wetting agent which comprises at least one compound of the formula ##STR1## wherein R1 is a hydrocarbyl group having about 8 to about 150 carbon atoms; R | 05/11/1993 |
| 5200551 | Method of preparing an intermediate for the manufacture of bambuterol The present invention relates to an improved method for the preparation of an intermediate for bambuterol, i.e. for the preparation of 2'-bromo-3,5-di[N,N-dimethylcarbamoyloxy]acetophenone (1), by reacting 3,5-dihydroxyacetophenone with N,N-dimethylcarbam... | 04/06/1993 |
| 5194660 | Processes for producing carbamates and isocyanates Processes for producing carbamates comprise contacting a first reactant selected from primary amine components, secondary amine components, urea components and mixtures thereof; carbon monoxide; at least one organic hydroxyl component and at least one oxy... | 03/16/1993 |
| 5189205 | Process for preparing isocyanates A process for preparing isocyanates comprising (a) contacting carbon dioxide and a primary amine in the presence of an aprotic organic solvent and an organic, nitrogenous base to produce the corresponding ammonium carbamate salt, and (b) reacting the ammo... | 02/23/1993 |
| 5155131 | Alkylthioethanamine carbamic acid derivatives and their use in biocidal compositions Alkylthioalkylamine carbamic acid derivatives are prepared which correspond to the formula: ##STR1## wherein R and R1 are both independently alkyl groups containing from 6 to 16 carbon atoms, and m and n are both independently integers of ... | 10/13/1992 |
| 5110986 | Synthesis of N-t-alkyl-1,2-diacylhydrazines This application relates to a process for preparing a N-t-alkyl-1,2-diacylhydrazine by reacting a 1,3,4-oxadiazole with a tertiary alkyl cation precursor in the presence of a strong acid catalyst. Preferably, the 1,3,4-oxadiazole is a 2,5-disubstituted-1,... | 05/05/1992 |
| 5109011 | P-acylaminophenoxycarbamates and derivatives This invention relates to p-acylaminophenoxycarbamates having the formula ##STR1## where R1 and R2 are each independently hydrogen, loweralkyl, aryl and arylloweralkyl; R3 is hydrogen, loweralkyl, aryllowerallkyl; R | 04/28/1992 |
| 5079076 | Composition and polymer fabrics treated with the same This invention relates to a composition prepared by reacting, in the presence of a redox initiator and a mineral acid, (a) at least one hydroxyl-containing imide, amide or mixtures thereof of a hydrocarbyl substituted carboxylic acid or anhydride having a hydr... | 01/07/1992 |
