Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 7601865 | Recovery of organic acids A method is disclosed for the recovery of an organic acid from a dilute salt solution in which the cation of the salt forms an insoluble carbonate salt. A tertiary amine and CO2 are introduced to the solution to form the insoluble carbonate salt and a com... | 10/13/2009 |
| 7329759 | Illudin analogs useful as antitumor agents The present invention provides illudin analogs of the general formula (I): where R1 is (CH2)n—X—Y or H; n is 0 to 4; X is O or S or N or absent; and Y... | 02/12/2008 |
| 7173151 | Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals The invention relates to arylcycloalkyl-substituted derivatives and to their physiologically acceptable salts and physiologically functional derivatives. What is described are compounds of the formula I, i... | 02/06/2007 |
| 6953850 | Protecting groups for carbohydrate synthesis The invention provides collections of orthogonally-protected monosaccharides as universal building blocks for the synthesis of glycoconjugates of non-carbohydrate molecules, neo-glycoconjugates and oligosaccharides. This orthogonal protection strategy allows for the... | 10/11/2005 |
| 6909014 | Intermediates for the synthesis of ether compounds The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a compo... | 06/21/2005 |
| 6884821 | Carboxylic acid derivatives and drugs containing the same Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R1 is hydro... | 04/26/2005 |
| 6855832 | O- or S-substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity Compounds of the formula where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity. ... | 02/15/2005 |
| 6740778 | Method for the preparation of oleanolic acid and/or maslinic acid The present invention relates to a method for preparing oleanolic acid and/or maslinic acid and physiologically acceptable salts thereof, which comprises the steps of extracting olive plant and/or products obtained in the olive oil-manufacturing processes with water... | 05/25/2004 |
| 6723843 | Oligosaccharide synthesis The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-glycoside type to... | 04/20/2004 |
| 6573337 | Oligosaccharide synthesis The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-g... | 06/03/2003 |
| 6495711 | Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters The invention relates to a process for preparing (-)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by the formula (I) ##STR1## wherein R1 and R2 are as described within the specification.... | 12/17/2002 |
| 6476258 | Process for producing aryloxyacetic acids An industrially advantageous process for producing an aryloxyacetic acid represented by the formula (2): ##STR1## wherein m represents an integer of 1 or 2, n represents an integer from 0 to 4, Ar represents a aromatic hydrocarbon ring, each Rs independen... | 11/05/2002 |
| 6444843 | Producing method of (hydroxyalkyl) alicyclic carboxylic acids and intermediates for producing the same and producing method of such intermediates (Acyloxyalkyl)aromatic carboxylic acids are produced by partial oxidation of alkyl substituted aromatic compounds which are represented by the following General Formula (1) CHR1 R2 --Ar--(R3)n (1) (where Ar is an ar... | 09/03/2002 |
| 6437177 | -hydroxy, -amino, and halo derivatives of ଲ-sulfonyl hydroxamic acids as matrix metallopropteinases inhibitors The present invention provides a compound of formula I ##STR1## or pharmaceutical acceptable salts thereof wherein R1 is C4-12 alkyl, C4-12 alkenyl, C4-12 alkynyl, --(CH2)h --C3-8 | 08/20/2002 |
| 6420612 | Bicycloheptene derivatives and processes for the preparation of the same Bicycloheptene compounds represented by general formula (1) and being useful as intermediates for the production of agricultural chemicals or drugs (wherein X is hydroxycarbonyl, hydroxymethyl, halogenomethyl, nitromethyl, or methylthiomethyl); and a proc... | 07/16/2002 |
| 6417389 | Process for the preparation of HPB esters This invention relates to a novel advantageous process for the stereoselective preparation of 2-hydroxy-4-phenylbutyrates (HPB esters) and of their precursors. This is done by starting from readily accessible -unsaturated -hydroxy-γ-keto es... | 07/09/2002 |
| 6211197 | Prostaglandin receptor ligands Compounds and methods for treating prostaglandin mediated diseases, and certain pharmaceutical compositions thereof are disclosed. The compounds are represented by formula II: Ar1 --W--Ar2 --X--Q II The compounds of the invention are str... | 04/03/2001 |
| 6191292 | Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof The invention relates to precursors of the A-ring of vitamin D, of the formula (I): ##STR1## in which A, R, R1 and R2 are as defined in the specification. The invention also relates to a method of preparing compounds (I) comprising t... | 02/20/2001 |
| 6136853 | Sordarin derivatives PURPOSE: To produce a novel antibiotic substance zofimarin having antimicrobial activity against fungi and obtain an antimicrobial agent containing the antibiotic substance zofimarin as an active constituent, by cultivating a microorganism, belonging to t... | 10/24/2000 |
| 6130354 | Process for the preparation of shikimic acid and its derivatives The present invention discloses a process for the preparation of shikimic acid or its derivatives from quinic acid or its derivatives by dehydration with Vilsmeier reagent. The present invention further discloses intermediates produced by this process and... | 10/10/2000 |
| 6103932 | Substituted cyclic amino acids as pharmaceutical agents Substituted cyclic amino acids of formula ##STR1## are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropatholo... | 08/15/2000 |
| 6066763 | Process for preparing free -hydroxy acids from ammonium salts thereof A process for preparing -hydroxy acids by heating ammonium salts of -hydroxy acids of general formula (I), removing the formed ammonia and water, adding water to the residue, and heating the obtained mixture, wherein R is hydrogen, C1 | 05/23/2000 |
| 6025518 | Substituted cyclopentene derivatives and method for preparing the same A substituted cyclopentene derivative of formula (V): wherein X1 is (-OZa, ଲ-H) or (-H, ଲ-OZa), X3 is (-OZd, ଲ-H), (-H, ଲ-OZd), or oxygen atom... | 02/15/2000 |
| 6010733 | Aspartylamide derivatives and sweeteners Novel aspartylamide derivatives such as N-(-L-aspartyl-(1R,2S,4S)-1-methyl-2-hydroxy-4-phenylhexylamide, N--7(N'-3,3-dimethylbutylaspartyl)-(1R,2S,4S)-1-methyl-2-hydroxy-4- phenylhexylamide) and the like, and a sweetener containing the a... | 01/04/2000 |
| 6004905 | Hyperabas: biologically active abscisic acid analogs with unsaturated carbon substituents at the 8'-methyl or 9'-methyl carbon atoms The invention disclosed relates to a new class of abscisic acid (ABA) analogs of formula I ##STR1## wherein one of R1 is alkenyl, alkynyl, aryl, cycloalkenyl, other farther substituted carbon chain including deuterium containing residues, ... | 12/21/1999 |
| 5968916 | Fluoroalkenyl compounds and their use as pest control agents Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds are particularly useful for systemic control of pests.... | 10/19/1999 |
| 5916919 | Retrovirus protease inhibitors A compound composition and method of treating a retrovirus infection are disclosed. In particular, isolated triterpenes have been shown to have significant inhibitory activity against HIV-1.... | 06/29/1999 |
| 5859054 | Leukotriene B4 derivatives, process for their production and their use as pharmaceutical agents Pharmacologically active leukotriene-B4 derivatives of general formula I, ##STR1## are described, in which R1 represents CH2 OH, CH3, CF3, COOR4, CONR5 R6, or R | 01/12/1999 |
| 5859284 | Preparation of carbocyclic compounds The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the syn... | 01/12/1999 |
| 5808134 | Cyclopropane derivatives and method of preparing the same An intermediate for the production of (3-oxo-2-oxobicyclo3,1,0!hexan-1-yl) methanol represented by formula (II): ##STR1## selected from the group of compounds (9)-(11) as shown below, wherein R1 represents a lower alkyl group, R3 | 09/15/1998 |
| 5792876 | Process for producing acetals A process is described for producing acetals comprising reacting an aldehyde or a ketone with an alcohol in the presence of a titanium compound having an acetylacetone as a ligand, or in the presence of a compound selected from the group consisting of sta... | 08/11/1998 |
| 5750765 | 7-substituted quinone methides as inhibitors for unsaturated monomers Ethylenically unsaturated monomers are protected from premature polymerization during manufacture and storage by the incorporation therein of an effective stabilizing amount of a 7-substituted quinone methide compound.... | 05/12/1998 |
| 5714517 | Fluoroalkenyl compounds and their use as pest repellents Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds, for example, 3,4,4-trifluoro-3-butene-1-amine or 3,4,4-trifluoro-3-butenoic acid, are particularly useful ... | 02/03/1998 |
| 5705529 | N-benzoyl amino acid derivatives pharmaceutical compositions containing them and process for preparing same The invention relates to novel N-benzoylamino acid derivatives of the general formula (I), ##STR1## wherein R1 and R2, which are the same or different, stand for a hydroxyl group optionally bearing an acetyl group; or a C1-... | 01/06/1998 |
| 5639902 | (Cyclohexyl)alkene compounds The invention relates to a compound selected from these of formula (I): ##STR1## in which R1, R2, R3, R4, R5 and B are as defined in the description, their enantiomers and diastereoisomers, their Z an... | 06/17/1997 |
| 5583247 | 7-substituted quinone methides as inhibitors for unsaturated monomers Ethylenically unsaturated monomers are protected from premature polymerization during manufacture and storage by the incorporation therein of an effective stabilizing amount of a 7-substituted quinone methide compound.... | 12/10/1996 |
| 5502075 | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents Leukotriene-B4 derivatives of formula I ##STR1## their salts with physiologically compatible bases and their cyclodextrin clathrates are described.... | 03/26/1996 |
| 5488136 | Process for the racemization of nonracemic 3-oxyocylopentane- or -hexanecarboxylic acids or their esters with C1 -C6 -alcohols Racemates are obtained from non-racemic 3-oxocyclopentane or 3-oxocyclohexane carboxylic acids or their esters by esterification and ketalization of the non-racemic acid with orthoformic acid ester in an alocohol, racemization and hydrolysis of the produc... | 01/30/1996 |
| 5473103 | Biopolymers derived from hydrolyzable diacid fats A monomeric diacid derivative includes at least two fatty acids coupled by a hydrolytically or enzymatically degradable bond. In a biological environment, the bond degrades forming naturally occurring fatty acid products thereby allowing elimination.... | 12/05/1995 |
| 5449684 | Cytotoxic compounds Compounds isolated from a marine sponge, and derivatives thereof, have the formulae: ##STR1## in which R1 is H or lower alkyl; R2 is OH or CH3 ; R3 is OH or CH3, and R4 H or MPTA. The ... | 09/12/1995 |
