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Class 562/493 - Monocyclic


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid contains only one carbocyclic
No. of patents: 250
Last issue date: 01/10/2012


1              
NumberTitleIssue Date
8093422Method for deuteration of an aromatic ring
The present invention relates to a method for deuteration of a compound having an aromatic ring, using an activated catalyst, and the method comprises reacting a compound having an aromatic ring with heavy hydrogen source in the presence of an activated catalyst sel...
01/10/2012
7750182Process for production of iodine compounds and process for production of high-purity 5-iodo-2-methylbenzoic acid
Provided is a production method for an iodine compound in which iodine is reacted with a substrate in the presence of a porous material having a pore diameter of 500 nm or less or in the presence of the above porous material and an oxidizing agent and a production p...
07/06/2010
7723538Sulfonamides as L-CPT1 inhibitors
The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as def...
05/25/2010
7645901Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
01/12/2010
7572935Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
08/11/2009
7439372Therapeutic compounds
A compound having a structure is disclosed herein. Compositions, medicaments, and therapeutic methods related thereto are also disclosed. ...
10/21/2008
7365225Aryl dicarboxamides
The present invention is related to aryl dicarboxamides of formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose...
04/29/2008
7294278Method for oxygenating wastewater
A method and apparatus creates gas-enriched fluid that is used to treat wastewater. In one embodiment, the wastewater is withdrawn from a supply of wastewater to be treated, and the wastewater is delivered in an atomized manner to a vessel pressurized with gas to fo...
11/13/2007
7176240Pentanoic acid derivatives
The compound of the formula (I): wherein R1 is alkyl substituted by fluorine(s); R2 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR3R4, in w...
02/13/2007
7109238Calcilytic compounds
Novel calcilytic compounds and methods of using them are provided. ...
09/19/2006
7057067Process for the preparation of 2-halobenzoic acids
The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: ...
06/06/2006
7057038Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids
One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer...
06/06/2006
7057055Process for preparing a deuterated or tritiated compound
A process for labeling organic compounds with deuterium and tritium is described using specific catalysts. ...
06/06/2006
7015349Reduction of hair growth
Compositions including a conjugate of α-difluoromethylornithine can be applied topically to reduce hair growth. ...
03/21/2006
7008535Apparatus for oxygenating wastewater
A method and apparatus creates gas-enriched fluid that is used to treat wastewater. In one embodiment, the wastewater is withdrawn from a supply of wastewater to be treated, and the wastewater is delivered in an atomized manner to a vessel pressurized with gas to fo...
03/07/2006
6989462Synthesis of 2-chloromethyl-6-methylbenzoic ester
A process is described for preparing compounds of formula (I) where R is H, optionally halogen-substituted alkyl, cycloalkyl, aryl, alkyl-aryl or heteroaryl, and, in alkyl and cycloalkyl, one or more CH2 grou...
01/24/2006
6943257Process for preparation of aromatic halides from aromatic amines
The present invention provides a process for preparing an aromatic bromide or aromatic iodide from an aromatic amine derivative using nitrite anion and halodimethylsulfonium halide generated in situ from hydrobromic acid/DMSO or hydriodic acid/DMSO. The process for ...
09/13/2005
69366365-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity
Compounds of the formula: where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects...
08/30/2005
6727098Biaryl-type compounds, CD color fixing agent and method for determination of absolute configuration
A novel achiral biaryl-type compound and a circular dichroism (CD) color fixing agent are provided. Furthermore, a method for determining an absolute configuration of a chiral compound is carried out by introducing the above achiral biaryl-type compound into the chi...
04/27/2004
66898912-bromomethyl-6-methyl-benzoic acid and a process for the preparation thereof
A process for the preparation of 2-bromomethyl-6-methyl-benzoic acid (I) and derivatives thereof by selective bromination of 2,6-dimethylbenzoic acid (II) with sodium bromate and hydrobromic acid in the presence of light....
02/10/2004
6586625Synthesis of 2-halobenzyl alkanoic acid
A method for synthesizing compounds of Formula I ##STR1## in which R is alkyl or aryl and X is any halogen is described....
07/01/2003
6555078Method of preparing lithium salts
The present invention provides an inexpensive process for the preparation of lithium salts of formula LiX having a desired or required level of purity using lithium chloride and lithium sulfate. In the process of the invention, a lithium salt selected fro...
04/29/2003
6489507Process for the synthesis of 3,5-bis(trifluoromethyl)benzoic acid
The present invention is concerned with a novel process for the preparation of 3,5-bis(trifluoromethyl)benzoic acid (CAS 725-89-3). This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particu...
12/03/2002
6462227Stabilized o-iodoxybenzoic acid compositions and process for the preparation thereof
Compositions that comprise, for one mole of o-iodoxybenzoic acid, from 0.5 to 4 moles of an aliphatic acid of formula CH3 (CH2)n COOH, in which n is from 8 to 20, of a benzenecarboxylic acid of formula ##STR1## in which R...
10/08/2002
6455725Substituted cinnamic acids and cinnamic acid esters
The invention relates to substituted cinnamic acids and cinnamic acid esters of formula (I), wherein X represents F, Cl or J and R1 and R2 are the same or different and represent hydrogen, an optionally substituted C1 -C
09/24/2002
6420601Process for the preparation of 3,5-bis(trifluoro-methyl)-benzoyl chlorides and novel 3,5-bis(tri-halogenomethyl)-and 3,5-dimethylbenzoyl halides
3,5-Bis(trifluoromethyl)benzoyl chlorides optionally substituted with fluorine or chlorine are advantageously prepared by converting 3,5-dimethylbenzoic acids optionally substituted with fluorine or chlorine into the corresponding acid chlorides; complete...
07/16/2002
6414186Process for producing chloromethylphenylacetic acid
A method for preparing chloromethylphenylacetic acids represented by formula (II): ##STR1## wherein a methylphenylacetic acid represented by formula (I): ##STR2## is reacted with a chlorine gas, in an inert solvent, under the irradiation with light o...
07/02/2002
6410783Method of producing carboxylic acid salts
The present invention is a method of producing dry, alkali metal or ammonium carboxylic acid salt particles. In accordance with the invention, a molten carboxylic acid is mixed with a solution of an alkali metal-containing or ammonium-containing alkaline ...
06/25/2002
6391823Separation process
A process for separating a compound from a mixture of different compounds is disclosed for compounds comprising at least two negatively charged groups connected by a linker group. The process comprises treating the mixture with a material comprising layer...
05/21/2002
6392084Method for production of organic fluorine compound
A method for the production of an aromatic fluorine compound is provided which is capable of preventing the occurrence of benzoic acid fluorides during the course of a halogenation exchange reaction or allowing removal of the benzoic acid fluorides formed...
05/21/2002
6388123Substituted phenyl keto enols as pesticides and herbicides
The present invention relates to novel compounds of the formula (I) ##STR1## in which Het represents one of the groups ##STR2## in which A, B, D, G, V, W, X, Y and Z are as defined in the description, processes and intermediates for their preparation, and to ...
05/14/2002
6362365Preparation of trifluorobenzoic acids
The present invention relates to a process for preparing trifluorobenzoic acids of the formula ##STR1## in which R is a straight-chain or branched alkyl radical having 1 to 6 C-atoms, an unsubstituted phenyl radical, a substituted phenyl radical whic...
03/26/2002
6348624Process for making certain benzoic acid compounds
The subject invention involves processes for making 2,4-difluoro-3-Q1-benzoic acid, wherein Q1 is derived from an electrophilic reagent, comprising the steps of: (a) treating 1-bromo-2,4-difluorobenzene with a strong, non-nucleophilic base; then trea...
02/19/2002
6333431Processes for the preparation of fluorinated benzoic acids
An object of the present invention is to provide a commercially advantageous process for preparing a fluoro benzoic acid. The process according to the present invention comprises either alkylating a fluoro benzoic acid of the formula ##STR1## wherein...
12/25/2001
6307091Trifluoro-substituted benzoic acid, esters thereof and processes for preparing the same
The present invention is to provided a trifluoro-substituted benzoic acid, an ester thereof, particularly 2,3,4-trifluoro-5-iodobenzonic acid, 2,3,4-trifluoro-5-trifluoromethylbenzonic acid, esters thereof, which are useful as a starting material for synt...
10/23/2001
6303812Isolation of products from selective dehalogenation of haloaromatics
Disclosed is a method of isolating the aromatic product formed when a substrate having the general formula ##STR1## is dehalogenated, forming a product mixture of copper salts and aromatic product, where X is the halogen removed from the substrate to form...
10/16/2001
6288271Process for the preparation of (2,2,2-trifluoroethoxy)benzoic acids
A process for producing trifluoroethoxybenzoic acids or salts thereof by reaction of halobenzoic acids or salts thereof with 2,2,2-trifluoroethanol in the presence of a strong base and copper containing materials. The compounds obtained by the process of ...
09/11/2001
6268527Method for producing benzoic acid derivatives
The invention relates to a method for producing a benzoic acid derivative represented by the general formula (1). The method includes the step of reacting an aromatic compound represented by the general formula (2), with carbon monoxide and a hydroxy comp...
07/31/2001
6268513Phosphine ligands metal complexes and compositions thereof for cross-coupling reactions
The present invention discloses new efficient processes for various bond forming reactions, including Suzuki reactions and aryl aminations. Organic compounds (e.g., ligands), their metal complexes and compositions using those compounds, provide useful cat...
07/31/2001
6265601Methods for using phosphine ligands in compositions for suzuki cross-coupling reactions
The present invention discloses new efficient processes for various bond forming reactions, including Suzuki reactions. Organic compounds (e.g., ligands), their metal complexes and compositions using those compounds, provide useful catalysts. The inventio...
07/24/2001
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