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Patent No. 6099319

Neuroimaging as a Marketing Tool

Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.

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Class 562/471 - Oxy, bonded directly to a ring, in same side chain as carboxyl, or salt thereof


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid contains an oxy group which is
No. of patents: 235
Last issue date: 01/24/2012


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NumberTitleIssue Date
8101794Crystalline forms of a 3-carboxypropyl-aminotetralin compound
The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1 -diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid for...
01/24/2012
8049035Crystalline potassium salt of lipoxin Aanalogs
This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characte...
11/01/2011
7906678Crystalline potassium salt of lipoxin A4 analogs
This invention is directed to the crystalline potassium salt of a lipoxin A4 analog of Formula (I): processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characte...
03/15/2011
7723537Skin lightening agents, compositions and methods
Disclosed is a coumarin derived compound of formula (I) as skin lightening agent alone or in combination with other skin benefit agents and together with a cosmetic vehicle: ...
05/25/2010
7714163Process for preparing quaternary acid and ammonium salts
A process for preparing a quaternary ammonium salt of a fibric acid, represented by the following reaction scheme: is carried out in a single operation starting from a phenol of formula (I), an α-halogenated ester of formu...
05/11/2010
7649110Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q—L1—P—L2—M—X—L3—A wherein the definitions of the variables ...
01/19/2010
7547802Compounds for the treatment of metabolic disorders
Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. ...
06/16/2009
7385082Preparation of 1,3-diphenylprop-2-en-1-one derivatives
The invention relates to a method for the preparation of de 1,3-diphenylprop-2-en-1-one substituted on one of the two phenyl groups by a carboxyalkyloxy group or a carboxyalkylthio group. ...
06/10/2008
7361686Compounds for the treatment of metabolic disorders
Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyper-lipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. Formula (I) wherein n is 1 or 2; m is 2 or 3; ...
04/22/2008
7348453Labile linkage for compound delivery to a cell
Described are ortho carboxy phenol derived acetals and compositions containing ortho carboxy phenol derived acetals which are useful for delivering biologically active compounds to cells. The acetals can be used to reversibly link up to three different molecules and...
03/25/2008
7342127Substituted anilide ligands for the thyroid receptor
Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7,...
03/11/2008
7338960Phenylalkanoic acid and phenyloxyalkanoic acid derivatives as hPPAR activators
A compound of formula (I) or a pharmaceutically acceptable salt, solvate, or hydrolysable ester thereof, wherein: ...
03/04/2008
73010504-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia. ...
11/27/2007
7302347Method for creating specific, high affinity nuclear receptor pharmaceuticals
This invention pertains to agonists that activate nuclear receptors. These agonists include an extension that contacts a region of the nuclear receptor outside the native ligand binding pocket. Methods for producing, identifying and designing such agonists are inclu...
11/27/2007
7276571Process for making phenylene dioxydiacetic acid and use thereof
A process for making phenylene dioxydiacetic acid comprises (a) contacting a dihydroxybenzene under reaction conditions with a salt of haloacetic acid in a solution without adding a haloacetic acid to produce a salt of phenylene dioxydiacetic acid; and (b) optionall...
10/02/2007
7268249Production process of optically pure 2-(4- hydroxyphenoxy)-propionic acid compounds
A process for producing optically pure R-hydroxyphenoxypropanoic acid or a salt or ester thereof by reaction of hydroquinone or a salt thereof with an S-halopropanoic acid or a salt thereof in the presence of a mild reducing agent. ...
09/11/2007
7238835Process for the preparation of substituted 2-(phenoxymethyl) benzoic acids
The invention relates to a process for the preparation of a compound of the general formula (I) in which a) a compound (II) is reacted in the presence of a base B1 with a compound (III) and
07/03/2007
7129274Phenoxy carboxylic acid compounds and compositions for delivering active agents
Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
10/31/2006
7087644Derivatives of dicarboxylic acid having pharmaceutical properties
The invention relates to compounds of formula (I) as well as the salts and stereoisomers thereof wherein the several variable groups are as defined in the specification and claims. Processes fo...
08/08/2006
7067640Cross-linked chiral compounds and methods of making thereof
The invention relates to a method which comprises synthesizing bifunctional compounds then chiral compounds from the bifunctional compounds, also to synthesizing supports comprising these chiral compounds, and the use of these supports for preparing or separating en...
06/27/2006
6924390Surface coating agents
Compounds useful as surface coating agents, including compounds of the formula: wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpo...
08/02/2005
6884907Hydroxamic acids and acyl hydroxamines as naaladase inhibitors
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neurona...
04/26/2005
6864287Derivatives of dicarboxylic acid having pharmaceutical properties
The present invention relates to the compounds of the general formula (I) and their salts and stereoisomers for the production of medicaments for the treatment of cardiovascular disorders. ...
03/08/2005
6784134Catalyst for preparation of unsaturated aldehyde and unsaturated carboxylic acid
A catalyst suited for catalytic vapor-phase oxidation of isobutylene, t-butanol or propylene to produce respectively corresponding unsaturated aldehyde and unsaturated carboxylic acid is provided. Said catalyst consists of ring-formed shaped bodies composed of (i) a...
08/31/2004
6756508Cinnamic acid salts, processes for their preparation, and their use as medicaments
The present invention relates to new cinnamic acid salts of salmeterol, processes for the preparation thereof as well as the use thereof as pharmaceutical compositions. ...
06/29/2004
6730798Process for the preparation of substituted octanoyl amides
Compounds of formula (II) are simultaneously halogenated in the 5 position and hydroxylated in the 4 position under lactonization, the halolactone is converted into a hydroxylactone and then the hydroxy group into a leaving group, the leaving group is replaced with ...
05/04/2004
6603040Surface coating agents
Compounds useful as surface coating agents, including compounds of the formula: ##STR1## wherein X1 comprises a first photoreactive species; X2 comprises a second photoreactive species; Y comprises a nonpolymeric core molecule c...
08/05/2003
6602878Acylquanidine derivatives, method for preparing same, application as medicines and pharmaceutical compositions containing them
Acylquanidines of the formula ##STR1## wherein the substituents are defined as in the specification which are antagonists of the vitronectin receptor and inhibitors of cell adhesion and bone resorption mediated by the osteoclasts....
08/05/2003
65766636-Keto prostaglandin F1଱ and analogs for treating dry eye
Compositions and methods for the treatment of dry eye and related diseases utilizing 6-keto-PGF1଱ and its analogs are disclosed....
06/10/2003
6541473Resorcinol derivatives
The present invention relates to certain resorcinol derivatives and their use as skin lightening agents....
04/01/2003
6525093Compounds to treat diabetes and associated conditions
Compounds are provided that lower blood glucose concentrations, lower serum triglyceride concentrations, lower systolic blood pressure, and increase glucose uptake by adipose tissue, but do not affect the expression of PPAR-γ by adipose tissue....
02/25/2003
6495715Calcium channel blockers
The present invention provides compounds that block calcium channels having the Formula I shown below. ##STR1## The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy an...
12/17/2002
6492550Alpha-substituted thio, -oxo trifluoromethylketones as phospholipase inhibitors
Inhibitors of the cytosolic phospholypase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula ##STR1## where X, Z, X1, R1, ...
12/10/2002
6482852Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
This invention concerns compounds for inhibiting intracellular signal transduction, especially intracellular signal transduction mediated by one or more molecular interactions involving a phosphotyrosine-containing protein. This invention also relates to ...
11/19/2002
6342592Chiral compounds, their synthesis and use as a support
The invention relates to a method which comprises synthesising bifunctional compounds then chiral compounds from the bifunctional compounds, also to synthesising supports comprising these chiral compounds, and the use of these supports for preparing or se...
01/29/2002
6340762Method for optical resolution of piperidine carboxylic acid derivative
A method for producing an optically active piperidine carboxylic acid derivative, which comprises subjecting a piperidine carboxylic acid derivative of the formula (1): ##STR1## wherein Z is a protecting group for the carboxyl group, to optical resol...
01/22/2002
6337306Phenoxyacetic acid derivatives and their use as herbicides
Phenoxyacetic acid derivatives of the formula: ##STR1## wherein R1, R2, Xn and A are as defined herein, and a process for preparing the derivatives. The derivatives are used as herbicides....
01/08/2002
6316666Method for producing purified phenylenedioxydiacetic acids
A method for producing phenylenedioxydiacetic acids of high purity at high yield from crude phenylenedioxydiacetic acids which mainly contains phenylenedioxydiacetic acids represented by the following general formula (I): ##STR1## wherein, R represen...
11/13/2001
6274385Attached tags for use in combinatorial chemistry synthesis
The present invention relates to a process of coding and identifying individual members of a chemical combinatorial library synthesized on a plurality of solid supports which undergo mix and split synthesis. The process provides for tagging the solid supp...
08/14/2001
6172239Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharamaceutical compositions containing them
The invention relates to compounds of the formula ##STR1## The compounds have agreat affinity for the neurotensin receptors....
01/09/2001
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