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Class 562/450 - Amide


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid contains the carbonyl residue
No. of patents: 355
Last issue date: 09/27/2011


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NumberTitleIssue Date
4279836Hydroxamic acid derivative and method of preparing metoclopramide using same
2-Chloro-4-N-(ଲ-diethylaminoethyl)aminocarbonyl-5-methoxybenzhydroxami c acid of the formula, ##STR1## or its metal salt, a process for their preparation and a process for preparing metoclopramide of the formula, ##STR2## using the abo...
07/21/1981
4275229Polymers having improved water resistance and monomers for same
Monoethylenically unsaturated beta-carbonyl-containing carboxyl functional monomers and addition polymers containing them and other monoethylenically unsaturated monomers are disclosed, as are methods of coating substrates with the polymers to provide fil...
06/23/1981
4264515Process for manufacturing a N-acyl ଱-amino acid
A N-acyl ଱-amino acid is manufactured by reacting an unsaturated vegetable oil or a C8 -C30 mono-olefinic compound with an amide, carbon monoxide and hydrogen, in the presence of a cobalt catalyst. The process is operated in on...
04/28/1981
4254035Process for the production of 2-acetamidocinnamic acid
2-acetamidocinnamic acid and substituted 2-acetamidocinnamic acids are prepared by reacting glycine with an aromtic aldehyde in the presence of acetic anhydride and a tertiary amine and subsequently treating with water....
03/03/1981
4250183N-(Substituted amino)alkanoyl-aminoalkanoic acids and salts, their use and their compositions
N-substituted ω-aminoalkanoyl-ω-aminoalkanoic acids and their pharmacologically-acceptable salts (with a base) are useful, e.g., in pharmaceutical-composition form for the treatment or prophylaxis of diseases which are based on inadequate performance of...
02/10/1981
4250192Novel substituted phenylacetic acid amide compounds
Phenylacetic acid amide compounds of the formula ##STR1## in which R1 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R2 is hydrogen, lower alkyl, lower alkoxy, hal...
02/10/1981
42422734-(Monoalkylamino)benzoic acid amides and imidates
This disclosure describes 4-(monoalkylamino)benzoic acid amides and imidates useful as hypolipidemic and antiatherosclerotic agents....
12/30/1980
4235969Procainamide antigen conjugates and antibodies
Compounds are provided for use in the preparation of reagents which can be used in immunoassays for the determination of benzamides of N,N-dialkylethyleneamines. A linking group is provided, at a particular site of the drug, which provides a link between ...
11/25/1980
4228304Novel cyclohexanecarboxylic acid and its derivatives
The present invention relates to novel cyclohexanecarboxylic acid and its derivatives represented by the general formula: ##STR1## (wherein R1 is selected from the group consisting of hydrogen or methyl; R2 is selected from the ...
10/14/1980
4228184Carboxyalkylacylamino acids
New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors....
10/14/1980
4220590Asymmetric catalysis
New optically active bis phosphine compounds which are usful in optically active catalysts. Such catalysts are particularly useful in catalytic asymmetric hydrogenation....
09/02/1980
4194050Process for producing an enamide
Enamides are prepared by hydrogenating oximes having at least one hydrogen atom at the ଱-position in the presence of a carboxylic anhydride using a ruthenium catalyst. These enamides are important to obtain amino group-containing compounds by reduct...
03/18/1980
4182891଱-Acetylenic derivatives of ଱-amino acids
Novel acetylenic derivatives of ଱-amino acids of the following general structure: ##STR1## wherein Z is ଲ-methylthioethyl, ଲ-benzylthioethyl, S-(5'-desoxyadenosin-5' -yl)-S-methylthioethyl, γ-guanidinopropyl, or RHN(CH2
01/08/1980
4182904Method of racemizing optically active N-acyl amino acids in aqueous solution
A process has been invented for the racemization of optically active N-acylamino acids in aqueous solution which comprises treating said optically active N-acylamino acids with ketene....
01/08/1980
4182899Optical resolution of amino acids into optical antipodes
The present application relates to the optical resolution into optical antipodes of compounds of the formula ##STR1## as well as to salts consisting of an optical isomer of a compound of the above formula and an optical isomer of 2-aminobutanol. The ...
01/08/1980
4177109γ-glutamyl-p-aminoanilide derivatives for measuring activity of γ-glutamyl transpeptidase
A γ-glutamyl-p-aminoanilide derivative of the formula: ##STR1## wherein R1 and R2 are independently lower alkyl; and R3 is hydrogen, lower alkyl, carboxyl or sulfo, can be produced by reacting a N-phthalyl-γ-glutamy...
12/04/1979
41547562-Substituted-4'-(monoalkylamino)-acetophenones
This disclosure describes 2-substituted 4'-(monoalkylamino)-acetophenones useful as hypolipidemic and anti-atherosclerotic agents....
05/15/1979
4147873଱-Vinyl derivatives of ଱-amino acids
Novel vinyl derivatives of ଱-amino acids of the following general structure: ##STR1## wherein R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy...
04/03/1979
4124533Metal coordination complexes containing optically active phosphine or arsine ligands
Process for the homogeneous catalytic hydrogenation of ଲ-substituted-଱-acylamido-acrylic acids which yields, after hydrogenation, an optically active mixture. The process comprises the hydrogenation of ଲ-substituted-଱-acylamido-acr...
11/07/1978
4123611N-protected amino compounds
6-Aminoacylamidopenicillanic acid or 7-amino-acylamidocephalosporanic acids are produced in high yields by acylating 6-aminopenicillanic acid or 7-aminocephalosporanic acid with an amino acid, or a functional equivalent thereof, having its amino group pro...
10/31/1978
4120870Metal phosphine complex
Group IB and IIB metal phosphine complexes are disclosed. These complexes are reacted with rhodium complex precursors to form useful enantioselective hydrogenation catalysts. Also disclosed is a method of preparing useful compounds having optical activity...
10/17/1978
41139437ଲ-[(2-Amino-1,2-dioxoethyl)amino]acyl cephalosporins
7ଲ-[(2-Amino-1,2-dioxoethyl)amino]acyl cephalosporins of the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl or a salt forming ion; R1 is hydrogen, lo...
09/12/1978
4111925Hydrolysis of esters of ଱-L-aspartyl-L-phenylalanine
A process which comprises contacting alkyl esters of ଱-L-aspartyl-L-phenylalanine with an aqueous solution containing barium ions, at a reaction pH greater than 7, to form ଱-L-aspartyl-L-phenylalanine....
09/05/1978
4105789Carboxyalkylacylamino acids
New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors....
08/08/1978
4088657Process for manufacturing N-acyl derivatives of glycines ଱-substituted by radicals of aromatic nature and novel products thereof
This is an improved process of manufacturing N-acyl derivatives of glycines ଱-substituted by radicals with an aromatic nature by condensation of the addition product of glyoxylic acid and an amide, with an aromatic compound. In a first stage, the re...
05/09/1978
40255513-Amino-N-substituted succinamic acids
3-Amino-N-substituted succinamic acids, prepared by coupling of a protected L-aspartic acid derivative with the appropriate amine followed by cleavage of the protecting groups, are potent sweetening agents and also exhibit pharmacological, e.g. anti-infla...
05/24/1977
40112603-Amino-N-substituted succinamic acids and intermediates thereto
The above-captioned compounds, prepared by coupling of a protected L-aspartic acid derivative with the appropriate amine followed by cleavage of the protecting groups, are potent sweetening agents and exhibit also pharmacological, e.g. anti-inflammatory, ...
03/08/1977
4008281Asymmetric catalysis
New optically active bis phosphine compounds which are useful in optically active catalysts. Such catalysts are particularly useful in catalytic asymmetric hydrogenation....
02/15/1977
4002671Substituted alkyl, aryl, aralkyl thio alkanamine addition salts
Organic amine-organic acid addition salts are employed in compositions for topical application to a human being having a scalp or skin characterized by an excessive secretion of sebum to improve the condition of the scalp or skin by reducing said excessiv...
01/11/1977
3996288Method of producing aldehydes by hydroformylation
When an alcohol or its hydrochloric or hydrobromic acid ester is held at 50° to 200° C and 10 to 500 atmospheres in the presence of hydrogen, carbon monoxide, the amide of a carboxylic acid, and a carbonylation catalyst, an aldehyde having one more carb...
12/07/1976
3978101Rhodium complexes of asymmetric diphosphines, their preparation and their use
Optically active diphosphines of the formula: ##EQU1## in which the phosphinomethyl groups are trans to each other, from rhodium complexes useful as catalysts in hydrogenating substituted acrylic acids and their esters to optically active propionic a...
08/31/1976
3960927Olefinic derivatives of amino acids
Novel compounds of the following general formula are useful pharmacologic agents: ##EQU1## R is selected from hydrogen, alkylcarbonyl wherein the alkyl moiety contains from 1 to 4 carbon atoms, alkoxycarbonyl wherein the alkoxy moiety contains f...
06/01/1976
3959356Acetylene derivatives of amino acids
Novel compounds of the following general formula are useful pharmacologic agents: ##EQU1## R is selected from hydrogen, alkylcarbonyl wherein the alkyl moiety contains from 1 to 4 carbon atoms, alkoxy-carbonyl wherein the alkoxy moiety contains ...
05/25/1976
3949000Asymmetric diphosphines, their preparation and their use
Optically active diphosphines of the formula: ##EQU1## in which the phosphinomethyl groups are trans to each other, form rhodium complexes useful as catalysts in hydrogenating substituted acrylic acids and their esters to optically active propionic a...
04/06/1976
3941836Cycloaliphatic carboxamides
Fuel compositions for internal combustion engines containing Diels-Adler adducts of N-3-oxohydrocarbon acrylamides or N-3-hydroxyhydrocarbon acrylamides with conjugated diene compounds such as 1,3-butadiene, cyclopentadiene. The adducts also have utility ...
03/02/1976
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