...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 7417164 | Fluorescent dyes for use in glucose sensing A novel class of compounds that includes HPTS-Cys-MA, and methods of making them are disclosed herein. The class of compounds including HPTS-Cys-MA are useful as fluorescent dyes for analyte detection. ... | 08/26/2008 |
| 7414076 | Methods and compositions for treating amyloid-related diseases Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease. ... | 08/19/2008 |
| 7399577 | Halogenated oxime derivatives and the use thereof Compounds of the formula (I) or (II) wherein R1 is C1-C10haloalkylsulfonyl, halobenzenesulfonyl, C2- C10haloalkanoyl, halobenzoyl; R2 is halogen or C1-C10 haloalkyl; Arl is pheny... | 07/15/2008 |
| 7244764 | Methods and compositions for treating amyloid-related diseases Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease. ... | 07/17/2007 |
| 6943268 | Method for induction of L-selectin shedding The invention provides anti-thiol reagents which inhibit enzyme activity of cell-associated protein disulfide isomerase (PDI) by oxidizing or blocking PDI active site vicinal thiol groups which normally participate in disulfide bond rearrangement of PDI substrates. ... | 09/13/2005 |
| 6531628 | Substantive water-soluble 2-hydroxy sulfobetaines of cinnamidoalkylamines Substantive UV-absorbing water-soluble 2-hydroxy sulfobetaine of cinnamidoalkylamines of Formula I. Hair, skin and fabric care compositions containing the compounds of Formula I. ##STR1## wherein, R1 is a substituent, selected from H, halo, --O... | 03/11/2003 |
| 6153789 | Purification of aqueous dye solutions The present invention provides a method of purifying an aqueous dye solution having an aldehyde and/or ketone impurity including a step of reacting the impurity with a hydrazine derivative, forming a water-insoluble hydrazone compound. The hydrazone compo... | 11/28/2000 |
| 6147253 | N-protected/N-substituted-beta-amino-hydroxy sulfonates N-protected/N-substituted alpha-amino aldehydes, which are useful as pharmaceuticals and pharmaceutical intermediates, can be stored and shipped in a more stable form as N-protected/N-substituted-beta-amino hydroxy sulfonates which can be readily converte... | 11/14/2000 |
| 6011140 | Reactive azo dyes with an aminonaphthalenesulfonic acid coupling component and intermediates therefor Reactive dyes of the formula ##STR1## where n is 1 or 2, G1 is hydrogen or hydroxyl, G2 is hydrogen or hydroxysulfonyl, G3 is hydrogen or arylazo, R1 is hydrogen or hydroxysulfonylmethyl, R2 is hydrogen or... | 01/04/2000 |
| 5948939 | Selective amidination of diamines An ω-guanidino--amino-acid (or its functional derivative) or a compound containing it may be prepared by the reaction of the ω-amino group of an ,ω-diamino acid (or its functional derivative) or a compound containing it with a formamidine... | 09/07/1999 |
| 5847201 | N-protected/N-substituted-beta-amino hydroxy sulfonates N-protected/N-substituted alpha-amino aldehydes, which are useful as pharmaceuticals and pharmaceutical intermediates, can be stored and shipped in a more stable form as N-protected/N-substituted-beta-amino hydroxy sulfonates which can be readily converte... | 12/08/1998 |
| 5817861 | Process for the preparation of an intermediate useful in the synthesis of iodinated contrast media A process for the preparation of (S)-N,N'-bis2-hydroxy-1-(hydroxymethyl)ethyl!-5-(2-acetoxy-propionylamino )-2,4,6-triiodo-isophthalamide, an intermediate useful for the synthesis of iopamidol, by reaction between L-5-(2-acetoxy-propionylamino)-2,4,... | 10/06/1998 |
| 5789557 | Reactive azo dyes with a coupler of the aminonaphthalene series Reactive dyes of the formula ##STR1## where n is 1 or 2, R1 is hydrogen or hydroxysulfonyl, R2 is hydrogen or hydroxyl, R3 is substituted C1 -C4 -alkyl, C5 -C7 -cycloalkyl or sub... | 08/04/1998 |
| 5763610 | Composition and processes for treating subterranean formations A composition comprising a nitrogen-containing olefinic compound and a process for using the nitrogen-containing olefinic compound to produce a water-soluble polymer which has applications in a subterranean formation are provided. The nitrogen-containing ... | 06/09/1998 |
| 5686492 | Disubstituted p-fluorobenzenesulfonamides Described herein are disubstituted p-fluorobenzenesulfonamides, containing a CF3 group, of general formula I ##STR1## which are suitable as NMR diagnostic agents.... | 11/11/1997 |
| 5326906 | Process for the extractive removal of phospho- and sulfobetaines from acidic reaction solutions The ampholytes are extracted from the reaction solution with a liquid cation exchanger which is immiscible with the acidic aqueous reaction solution, where the cation exchanger is dissolved in at least one organic solvent which is immiscible with water an... | 07/05/1994 |
| 5264622 | Water-soluble methylenebis(dialkylaniline) derivatives and application thereof Novel water-soluble methylenebis(dialkylaniline) derivatives of the following general formula and salts thereof are disclosed. They are useful as dye-forming substances in quantitative determination of peroxides in the copresence of peroxidase or the like... | 11/23/1993 |
| 5120872 | Compounds containing a 3-sulfoalkanoylamino or 3-sulfoalylsulfonylaminoaniline coupling component A compound of the formula ##STR1## in which R1 and R2 independently of one another are each C1 -C10 alkyl which is unsubstituted or substituted by hydroxyl, C1 -C4 alkoxy, phenyl, sulf... | 06/09/1992 |
| 5110985 | Process for preparing carboxyalkyl-substituted hydroxylamine A process for preparing a carboxyalkyl-substituted hydroxylamine represented by formula (I) ##STR1## where L represents an alkylene group; A represents a hydrogen atom, a sulfo group, a carboxy group, a phosphono group, a trialkylammonio group, ... | 05/05/1992 |
| 5026905 | Fluorescent dyes The present invention describes a class of dyes for use in staining cell samples and methods of making such dyes. A preferred class of dyes known as detergent dyes which possess the ability to stain cells in whole blood and are only slowly leached or lost... | 06/25/1991 |
| 4985595 | Aminobenzamide derivatives Aminobenzamide derivatives of the formula (I) ##STR1## wherein: R1 and R2 each represents a lower alkoxy group, R3 represents a hydrogen atom, a lower alkyl group, a lower acyl group, a lower alkoxycarbonyl group or --R | 01/15/1991 |
| 4978781 | Low-foam alkali-stable amphoteric surface active agents The present invention relates to low-foam alkali-stable surface active agents which are amphoteric. The subject materials are hydroxypropyl sultaines.... | 12/18/1990 |
| 4898944 | Precursors for the preparation of water-soluble triphendioxazine dyestuffs Precursors for the preparation of fiber-reactive triphendioxazine dyestuffs correspond to the general formulas: ##STR1## in which Y' is a vinyl, a beta-hydroxyethyl or an ethyl group which contains in the beta-position a substituent which can be elim... | 02/06/1990 |
| 4891159 | Low-foam alkali-stable amphoteric surface active agents Novel surface active agents of the formula: ##STR1## wherein R is selected from the group consisting of alkyl, aryl, alkylaryl groups of 2-18 carbons and alkoxymethyl wherein the alkoxy group is of 2-18 carbon atoms, R2 and R3 a... | 01/02/1990 |
| 4837330 | Preparation of sulfatobetaines Sulfatobetaines are prepared by reacting an adduct of a base having a tertiary N atom and sulfur trioxide with an alkylene oxide in the presence of an alkylene carbonate as a solvent.... | 06/06/1989 |
| 4781866 | Process for producing amidine sulfonic acid intermediates for guanidines An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H2 O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can th... | 11/01/1988 |
| 4704229 | Surface-active compounds of the sulfobetaines family, their manufacture and use, particularly for enhanced oil recovery New surface-active compounds of the sulfobetaines group are manufactured. They comply with the general formula: ##STR1## wherein each of R1, R2 and R3 is substantially a hydrocarbon radical, each of R4 and ... | 11/03/1987 |
| 4693850 | Methane sulfonic acid derivatives Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride. Included is a hydrogen peroxide oxidation of a thiourea (II) to a sulfonic acid (I) which may then be reacted with morpholine to form the carboxi... | 09/15/1987 |
| 4656270 | Process for producing guanidines such as linogliride Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride. Included is a hydrogen peroxide oxidation of a thiourea (II) to a sulfonic acid (I) which may then be reacted with morpholine to form the carboxi... | 04/07/1987 |
| 4656291 | Process for producing amidine sulfonic acids An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H2 O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can th... | 04/07/1987 |
| 4588435 | N-substituted amino propane sulfonic acid derivatives and plant growth regulating use The invention relates to new N-substituted amino propane sulfonic acid derivatives of the Formula I ##STR1## and salts and hydrates thereof, a process for the preparation thereof and plant growth regulating agents comprising the same wherein R1 | 05/13/1986 |
| 4562249 | Bis(4-((chloro substituted phenyl)azo)anilino methylenes There are described novel yellow to red azo compounds of the formula I ##STR1## wherein each D independently of the other is the radical of an aromatic or heterocyclic diazo component, each Z independently of the other is hydrogen or a C1 ... | 12/31/1985 |
| 4543216 | Polymerizable amino acid compounds and their production A polymerizable amino acid compound of the formula: ##STR1## wherein R1, R2 and R3 are each hydrogen or methyl, R4 is C1 -C20 alkyl optionally bearing at least one hydroxyl and optiona... | 09/24/1985 |
| 4536314 | Bleach compositions comprising non-linear aliphatic peroxycarboxylic acid precursors Detergent compositions, detergent additive products and bleaching compositions containing aliphatic peroxyacid bleach precursors of formula ##STR1## are provided, where L is a leaving group of defined formula whose conjugate acid has a pKa of from 6 ... | 08/20/1985 |
| 4521619 | Therapeutically useful sulphur-containing benzylidene derivatives Benzylidene derivatives of the formula: ##STR1## wherein n represents an integer from 1 through 4, R represents an amino radical, a monoalkylamino group containing 1 through 4 carbon atoms in the alkyl radical, a dialkylamino group containing 1 throu... | 06/04/1985 |
| 4507446 | Water-soluble or water-dispersible resinous sulphur or phosphorus containing salts, their preparation, and their use in coatings Water-soluble or water-dispersible resinous salts are prepared by `tipping` an epoxy resin with a phenol, then carrying out a Mannich reaction with an aldehyde (usually formaldehyde) and an aminosulfonic or aminophosphonic acid, followed by salt formation... | 03/26/1985 |
| 4499272 | NH4+ Or group IA metal 2,7-dimethyl-1,2,3-tetrahydro-ଲ-hydroxy-1-quinolinepropanesulfonate s 2-Hydroxy-3-halo-1-propanesulfonates are reacted with certain arylamines, preferably in the presence of a base such as KOH or NaOH in one or more of ethylene glycol, propylene glycol, 2-ethoxyethanol and the like to give 2-hydroxy-3-(arylamino)-1-propanes... | 02/12/1985 |
| 4452746 | Polymerizable amino acid compounds and their production A polymerizable amino acid compound of the formula: ##STR1## wherein R1, R2 and R3 are each hydrogen or methyl, R4 is C1 -C20 alkyl optionally bearing at least one hydroxyl and optiona... | 06/05/1984 |
| 4414414 | 4,4'-Dithiodianil Novel 4,4'-dithiodianil compounds are prepared by reacting 4,4'-dithiodianiline with an aromatic or pyridine aldehyde, such as 4-nitrobenzaldehyde. The novel dithiodianil compounds can be employed for detecting thiol compounds. They react with thiols to y... | 11/08/1983 |
| 4396714 | N-Sulfoalkylaniline derivatives N-sulfoalkylaniline derivatives in which at least one sulfoalkyl of 2 to 4 carbon atoms is attached to the nitrogen atom which are useful as dyestuff forming substances, a composition for determining the presence of peroxides using such compounds and the ... | 08/02/1983 |