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Class 562/425 - Having plural rings


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Processes wherein the alkali metal phenolate contains plural
No. of patents: 34
Last issue date: 04/18/2006


NumberTitleIssue Date
7030133Inhibitors of formation of advanced glycation endproducts (AGEs)
The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of reducing sugars in the blood an...
04/18/2006
6525210Chiral ligands, transition-metal complexes thereof and uses thereof in asymmetric reactions
Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include phospholanes, P,N ligands, N,N ligands, biphenols, and chelating phosphines. The ferrocene-based irridium (...
02/25/2003
6521786Process for the production of aromatic acids
A description is given here of a novel process for the production of monocarboxylic and polycarboxylic aromatic acids by the catalytic oxidation in homogeneous phase of aromatic compounds carrying at least one oxidizable substituent group attached directl...
02/18/2003
6337350Inhibitors of formation of advanced glycation endproducts (AGEs)
Derivatives of aryl and heterocyclic ureido and aryl and heterocyclic carboxamido phenoxy isobutyric acids have been found to inhibit the nonenzymatic glycation of proteins which often results in formation of advanced glycation endproducts and crosslinks....
01/08/2002
6316665Process for producing diacids by carboxylation of phenolic compounds
An oxidation free process for converting a hydroxy substituted aromatic to an aromatic diacid which comprises reacting a hydroxy substituted aromatic with excess basic salt in the presence of carbon dioxide at disproportionation/isomerization reaction con...
11/13/2001
6133475Process for producing 2-hydroxynaphthalene-3,6-dicarboxylic acid
The present invention relates to a process for preparing 2-hydroxynaphthalene-3,6-dicarboxylic acid which comprises reacting potassium 2-naphtholate and carbon dioxide at a temperature 290° C. or higher under a pressure 30 kg/cm2 (G) or higher...
10/17/2000
5927283Allosteric modifiers of hemoglobin
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The effect has particular application in a wide variety of treatments including hypoxia, hypothermia, ischemia, stroke, ARDS, COPD, surgic...
07/27/1999
5705521Use of allosteric hemoglobin modifiers in combination with radiation therapy to treat carcinogenic tumors
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The effect has particular application in radiation oncology applications. The compounds are capable of acting on hemoglobin in whole blood...
01/06/1998
5677330Medical uses of allosteric hemoglobin modifier compounds in patient care
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The effect has particular application in a wide variety of treatments including hypoxia, hypothermia, ischemia, stroke, ARDS, COPD, surgic...
10/14/1997
5648375Use of hydrophobic compounds and anesthetics in combination with allosteric hemoglobin modifiers
Allosteric hemoglobin modifier compound activity on p50 is potentiated by using the compound in combination with a hydrophobic compound such as an anesthetic....
07/15/1997
5599971Method for producing 1,4-dihydroxy-2-naphthoic acid
A method for producing 1,4-dihydroxy-2-naphthoic acid which comprises the steps of: subjecting 1,4-dihydroxynaphthalene into an alkali metal salt formation reaction in an organic medium capable of dissolving 1,4-dihydroxynaphthalene using an alkali metal ...
02/04/1997
5532406Process for preparing aromatic hydroxycarboxylic acids
A process for preparing aromatic hydroxycarboxylic acids or di-salts thereof by reaction of alkali metal phenolates or naphtholates with carbon dioxide, in the presence or absence of a further alkali metal salt, which comprises introducing the solid pheno...
07/02/1996
5312976Process for the preparation of 2-hydroxy-naphthalene-6-carboxylic acid
2-Hydroxy-naphthalene-6-carboxylic acid or its dipotassium salt is obtained in a good yield and purity without substantial formation of the isomeric compound 2-naphthol-3-carboxylic acid by reacting potassium ଲ-naphtholate with potassium carbonate i...
05/17/1994
5075496Manufacture of 2,6-hydroxynaphthoic acid
2,6-hydroxynaphthoic acid is made by reacting 2-naphthol with cesium or rubidium hydroxide to obtain cesium or rubidium naphthoxide, and reacting the naphthoxide with CO2 in the presence of cesium or rubidium carbonate....
12/24/1991
5011984Manufacturing method for 2-hydroxynaphthalene-6-carboxylic acid
The present invention provides a production of 2-hydroxynaphthalene-6-carboxylic acid improved in the yield and the selective ratio, in which ଲ-naphthol and water formed in the reaction system are eliminated therefrom through the reaction....
04/30/1991
4966992Process for production of aromatic hydroxycarboxylic acid
The present invention provides a method of production of aromatic hydroxycarboxylic acids by the reaction of alkaline metal salts of phenols or naphthols with carbon dioxide, in which free phenols or free naphthols produced as by-products in the reaction ...
10/30/1990
4916257Process for the purification of 2-hydroxynaphthalene-6-carboxylic acid
The invention relates to a process for purification of 2-hydroxynaphthalene-6-carboxylic acid by recrystallization. In this process, the crude acid is recrystallized from water-miscible linear or cyclic aliphatic ethers, aliphatic polyethers or aliphatic ...
04/10/1990
4873367Method for preparing 4-hydroxy-3-phenylbenzoic acid
4-Hydroxy-3-phenylbenzoic acid is prepared by carbonation of a 2-phenylphenol alkali metal salt in the presence of a liquid N,N-dialkylcarboxamide such as dimethylformamide. Carbonation may be effected at atmospheric pressure or at superatmospheric pressu...
10/10/1989
4780567Process for producing aromatic hydroxycarboxylic acids
This invention provides a process for selectively producing aromatic hydroxycarboxylic acids, which comprises subjecting a liquid mixture consisting of a polycyclic aromatic hydrocarbon, an alkali metal salt of an aromatic hydroxy compound and a free arom...
10/25/1988
4529817Process for preparing aromatic hydroxycarboxylic acids
Aromatic hydroxycarboxylic acids are prepared by reacting an alkali metal salt of an aromatic hydroxy compound in solid phase with carbon dioxide, by reacting an alkali metal salt of an aromatic hydroxy compound in the form of granules in a fluidized bed ...
07/16/1985
4508920Process for the preparation of aromatic hydroxycarboxylic acids
Aromatic hydroxycarboxylic acids are prepared by reacting alkali metal salts of aromatic hydroxy compounds in the solid phase with carbon dioxide in a process in which the alkali metal salt of the aromatic hydroxy compound is reacted at temperatures of 12...
04/02/1985
4345094Process for the production of 6-hydroxy-2-naphthoic acid
The production of 6-hydroxy-2-naphthoic acid from anhydrous potassium 2-naphthoxide and carbon dioxide is improved by forming a mixture of 0.8-1.2 moles of 2-hydroxynaphthalene per equivalent of potassium base, dehydrating the mixture, adding carbon dioxi...
08/17/1982
4345095Process for the production of 6-hydroxy-2-naphthoic acid
The production of 6-hydroxy-2-naphthoic acid from anhydrous potassium 2-naphthoxide and carbon dioxide is improved by forming a mixture of 0.8-1.45 moles of 2-hydroxynaphthalene per equivalent of potassium base, dehydrating the mixture, adding carbon diox...
08/17/1982
4329494Recycling techniques in the production of 6-hydroxy-2-naphthoic acid
The production of 6-hydroxy-2-naphthoic acid from anhydrous potassium 2-naphthoxide and carbon dioxide is improved by introducing 3-hydroxy-2-naphthoic acid to the initial stages of the process....
05/11/1982
4297508Process for producing 2 hydroxy-naphthalene-3-carboxylic acid
A process for producing 2-hydroxynaphthalene-3-carboxylic acid comprising reacting carbon dioxide with a homogeneous liquid mixture comprising an alkali metal salt of ଲ-naphthol, ଲ-naphthol and a specific alkylbenzene is disclosed....
10/27/1981
4287357Process for the production of 6-hydroxy-2-naphthoic acid
The production of 6-hydroxy-2-naphthoic acid from anhydrous potassium 2-naphthoxide and carbon dioxide is improved by forming a mixture of 0.8-1.2 moles of 2-hydroxynaphthalene per equivalent of potassium base, dehydrating the mixture, adding carbon dioxi...
09/01/1981
4239913Process for preparing 2-hydroxynaphthalenecarboxylic acids
A process for preparing 2-hydroxynaphthalenecarboxylic acids which comprises reacting a liquid mixture of 1 mole of an alkali ଲ-naphtholate, 0.05 to 3 moles of ଲ-naphthol, and 0.1 to 5 times the weight of the alkali ଲ-naphtholate of ligh...
12/16/1980
4057576Process for isolating 2-hydroxynaphthalene carboxylic acids from reaction mixtures of the alkali metal salts of 2-hydroxynaphthalene with carbon dioxide
An improved process for isolating 2-hydroxynaphthalenecarboxylic acids from reaction mixtures of the alkali metal salts of the 2-hydroxynaphthalene with carbon dioxide had been found which comprises diluting with water the reaction mixture which contains ...
11/08/1977
4038309Production of 2-hydroxynaphthalene-3-carboxylic acid
The production of 2-hydroxynaphthalene-3-carboxylic acid by heating sodium ଲ-naphtholate in the presence of an araliphatic compound containing two aromatic radicals and/or in the presence of an aromatic ether having at least one aromatic radical eth...
07/26/1977
4034006Process for the manufacture of alkali salts of 3,5-disubstituted 4-hydroxybenzoic acids and their free acids
A new process for the preparation of alkalimetal salts of 3,5-substituted 4-hydroxybenzoic acids and the free acids thereof, which comprises reacting a 2,6-disubstituted phenol in a mixture of water and a dipolar aprotic solvent with an alkalimetal hydrox...
07/05/1977
4032568Production of 2-hydroxynaphthalene-3-carboxylic acid
2-HYDROXYNAPHTHALENE-3-CARBOXYLIC ACID IS PRODUCED BY HEATING A MIXTURE OF POTASSIUM ଲ-NAPHTHOLATE AND SODIUM ଲ-NAPHTHOLATE TO A TEMPERATURE OF AT LEAST 180° C, reacting it with carbon dioxide and treating the salt formed with an acid. The pr...
06/28/1977
4020102Production of 2-hydroxynaphthalene-3-carboxylic acid
2-Hydroxynaphthalene-3-carboxylic acid is prepared by the reaction of sodium-ଲ-naphtholate with carbon dioxide, extraction of the reaction mixture in the presence of water with benzene or a benzene derivative in a specific ratio and separation of th...
04/26/1977
4017538Alkyl thio sulfinyl and sulfonyl oxamic compounds, compositions and methods of use
It has now been discovered that novel compounds of the figure below and their pharmaceutical compositions are useful in the prophylactic treatment of sensitized humans and animals for allergy and anaphylactic reactions of a reagin or non-reagin mediated n...
04/12/1977
4002675Manufacture of 2-hydroxy-naphthalene-3-carboxylic acid
A process for the manufacture of 2-hydroxy-naphthalene-3-carboxylic acid by heating sodium ଲ-naphtholate or a mixture of potassium ଲ-naphtholate and sodium ଲ-naphtholate with nitrogen compounds and/or polyphosphates containing at least 3...
01/11/1977
 
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