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| Number | Title | Issue Date |
| 8022246 | Neuroprotective compositions and methods Neurite outgrowth-promoting prostaglandins (NEPPs) and other electrophilic compounds bind to Keap1, a negative regulator of the transcription factor Nrf2, and prevent Keap1-mediated inactivation of Nrf2 and, thus, enhance Nrf2 translocation into the nucleus of neuro... | 09/20/2011 |
| 7858824 | Aralkyltetrahydropyridines, their preparation and pharmaceutical compositions containing them The present invention relates to compounds of formula (IIIo): in which n is an integer from 1 to 5; Ao represents a partially saturated carbonaceous bi- or tricycle; it also relates to the... | 12/28/2010 |
| 6538149 | ARYL OR HETEROARYL SUBSTITUTED 3,4-DIHYDROANTHRACENE AND ARYL OR HETEROARYL SUBSTITUTED BENZO [1,2-G]CHROM-3-ENE, BENZO[1,2-G]-THIOCHROM-3-ENE AND BENZO [1,2-G]-1,2-DIHYDROQUINOLINE DERIVATIVES HAVING RETINOID ANTAGONIST OR RETINOID INVERSE AGONIST TYPE BIOLOGICAL ACTIVITY Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinoid antagonist and/or retinoid inverse-agonist-like biological activity.... | 03/25/2003 |
| 6399549 | Condensates A cyclic compound comprising m units of the formula Ia. ##STR1## and n units of the formula (Ib) ##STR2## joined together to form a ring, wherein Y and y2 are divalent bridging groups which may be the same or different in each unit; Ro | 06/04/2002 |
| 6344585 | Preparation process of fluorenes A tetrahydrofluorene, which is represented by the following formula (I) ##STR1## wherein R1 to R6 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or R1 and R2 are combi... | 02/05/2002 |
| 6180816 | Anti-viral compounds The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.... | 01/30/2001 |
| 6180815 | Anti-viral compounds The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.... | 01/30/2001 |
| 6175034 | Anti-viral compounds The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.... | 01/16/2001 |
| 5380925 | Cyclic amino acids and derivatives thereof Novel cyclic amino acids which are useful in preparing biologically active peptides as well as a process for the preparation of D and L enantiomers of the cyclic amino acids are described where an N-protected derivative of the racemic cyclic amino acid is... | 01/10/1995 |
| 4963585 | Compound, WF11605 and derivative thereof The invention relates to a compound of antimicrobial activity of the formula ##STR1## wherein R1 is hydrogen or lower alkanoyl, R2 is hydrogen or ##STR2## in which R4, R5, R6 and R7 | 10/16/1990 |
| 4874890 | Process for the production of deuterated methyl acrylate or deuterated methyl methacrylate There is provided the improved process for the production of deutrated methyl acrylate or methacrylate by the direct substitution of deuterium for hydrogens in methyl acrylate or methacrylate in the presence of a platinum Group metal catalyst.... | 10/17/1989 |
| 4874891 | Open "D" ring hormone analogs Compounds of the formula: ##STR1## and the pharmaceutically acceptable esters thereof, wherein rings A and B are selected from the group consisting of ##STR2## wherein x represents an aromatic ring, or the presence or absence of 0, 1, or ... | 10/17/1989 |
| 4732897 | Steroidic 5-reductase inhibitors The present invention relates to new 4-aza-17ଲ-substituted 5-androstan-3-ones, to a process for their preparation, to pharmacological compostions containing them, and to the use of said compounds as inhibitors of androgen action by means of t... | 03/22/1988 |
| 4585576 | Liquid-crystal nematic substances What is described is an improved opto-electronic component and display which uses novel liquid crystal nematic substances for the control of the light transmission and for the display of numbers symbols and images. The novel nematic liquid crystal substan... | 04/29/1986 |
| 4361578 | D-Homosteroids The invention is directed to 3-oxo-D-homosteroids and derivatives thereof which are useful as antiantigens.... | 11/30/1982 |
| 4173648 | 3ଲ-Hydroxy-18ଲ-olean-9-en-30-oic acids 3ଲ-Hydroxy-18ଲ-olean-9-en-30-oic acids having anti-ulcer activity of the formula ##STR1## compositions containing the same and process for their preparation.... | 11/06/1979 |
| 4147777 | Sericosides and method of use Pharmaceutically active compounds of the formula ##STR1## wherein R1, R2, R3 and R4, which may be the same or different, each represents a hydrogen atom or a substituted or unsubstituted aliphatic or aromat... | 04/03/1979 |
| 4103025 | Novel terpenes Pharmaceutically active compounds of the formula ##STR1## wherein --OR1, --OR2, --OR3 and --OR4, which may be the same or different, each represents a free or esterified hydroxyl group and --COOR5 | 07/25/1978 |
| 4093712 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 06/06/1978 |
| 4076944 | 3ଲ,14ଲ-Dihydroxy-14,17-seco-D-bisnorandrostan-17-oic acid derivatives 15-Oxasteroids of the androstane, pregnane, estrane, and 19-norpregnane series are useful as hormonal agents.... | 02/28/1978 |
| 4033995 | D-homo steroids D-Homo-21-carboxylic acids of the formula ##STR1## the represents a single bond or a double bond; X is a hydrogen atom, a fluorine atom, or methylene; Y is a hydrogen atom, a fluorine atom, or a chlorine atom; Z is methylene, carbonyl, ଲ-hydroxy... | 07/05/1977 |
| 4029692 | Steroid carboxylic acids and derivatives The present disclosure relates to steroid carboxylic acids and derivatives thereof. More particularly, the disclosure is concerned with D-homosteroid carboxylic acids and their derivatives, a process for the preparation thereof and pharmaceutical composit... | 06/14/1977 |
| 4021478 | Preparation of carboxylic acids from glycidonitriles with ionic lewis acids Process for preparing carboxylic acids by converting a glycidonitrile to a 2-oxopropionitrile via use of an ionic Lewis acid, and conversion of the 2-oxopropionitrile to the carboxylate salt with a base and of the salt to the carboxylic acid with acid. Th... | 05/03/1977 |
| 4013713 | Diarylvinyl-dihydrophenanthrene compounds New diarylvinyl-dihydrophenanthrene compounds of the formula ##STR1## wherein R1, R1 ', R2, R2 ', R3 and R3 ' are identical or different and represent hydrogen, alkyl with 1 to 12 carbon ... | 03/22/1977 |
| 3976684 | 1-Succinoyl-2,4-disubstituted-4b,5,6,7,8,8a,9,10-octahydro-9-oxo-ph enanthrenes and compositions and methods for treating lipodemia 1-succinoyl-2,4-disubstituted-4b,5,6,7,8,8a,9,10-octahydro-9-oxo-phenanthre nes, e.g., 1-succinoyl-2,4-dimethoxy-4b,5,6,7,8,8a,9,10-octahydro-9-oxo-phenanthrene are prepared by treating a corresponding 2,4-dimethoxy-4b,5,6,7,8,8a,9,10-octahydro-9-oxo-... | 08/24/1976 |
| 3939193 | D-Homosteroids A novel class of D-homosteroids is disclosed. These compounds have potent endocrinal activity, particularly as anti-inflammatory agents.... | 02/17/1976 |
| 3932482 | Polyhydro-2-phenanthrylideneacetic acids and esters thereof Alkyl polyhydro-2-phenanthrylideneacetates are prepared by interacting the corresponding 2-oxopolyhydrophenanthrenes with a tri-lower-alkyl -phosphono-lower-alkanoate. Said alkyl polyhydro-2-phenanthrylideneacetates are hydrolyzed to the free acid,... | 01/13/1976 |