Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 7393969 | Particular calixarenes method for production and use thereof The present invention relates to calix[4]arenes which effectively bind alkali metal ions (Na+, K+) and transport them over phase boundaries, their preparation and use. ... | 07/01/2008 |
| 7371887 | Oligo(p-phenylene vinylene) amphiphiles and methods for self-assembly Amphiphilic oligo(p-phenylene vinylene) compounds and methods of use en route to self-assembled composites and device fabrication. ... | 05/13/2008 |
| 7355077 | Process for preparing tolterodine A process for preparing tolterodine with high purity. ... | 04/08/2008 |
| 7265245 | Compounds useful for the treatment of diseases associated with the formation of amyloid fibrils The present invention provides new amyloidogenesis inhibiting compounds of formula (I): in which R1 is a —NRaRb group, where Ra and... | 09/04/2007 |
| 7232920 | Process for stereoselective reduction of β-ketoesters In one aspect, the invention provides a process for the preparation of compounds of Formula I wherein R1 is —CN, —OP, alkyl, aryl or heteroaryl; wherein P represents any su... | 06/19/2007 |
| 7199259 | Resolution of α-(phenoxy)phenylacetic acid derivatives The present invention provides a method for producing an enantiomerically enriched α-(phenoxy)phenylacetic acid compound of the formula (I): from its enantiomeric mixture, where R1 is alkyl or haloalk... | 04/03/2007 |
| 7064124 | NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient A NF-κB inhibitor represented by the following formula (I) is provided: ... | 06/20/2006 |
| 6974872 | Process for production of piperidine derivatives The present invention discloses processes for preparing piperidine derivative compounds of the formulae: wherein n is 0 or 1; R1 is hydrogen or hydroxy; | 12/13/2005 |
| 6972294 | Compounds, their preparation and use Disclosed are novel compounds of formula (I) wherein A1, A2, Ar, R5, R6, R8, M, Q, Y, Z, k, m and n are as defined in the specification. These compounds are useful ... | 12/06/2005 |
| 6949618 | Polymer compound, precursor for the same and thin film-forming method using the same polymer precursor Provided are polyimide and a thin film thereof which have a three-dimensional structure and therefore are excellent in a mechanical strength and a heat resistance as compared with those of conventional linear polyimide. The polyimide is obtained from a salt of multi... | 09/27/2005 |
| 6943196 | NF-κB inhibitor comprising phenylmethyl benzoquinone as the active ingredient An NF-κB inhibitor having as an active ingredient a benzoquinone derivative represented by the general formula (1) wherein R1, R2, and R3 are each independently H, alkyl having 1 to 5 carbons, or alkoxy having 1 to 5 carbons; R... | 09/13/2005 |
| 6930197 | Antihistaminic piperidine derivatives and intermediates for the preparation thereof This invention relates to a process for the preparation of compounds of the formula: wherein R1 is C1-C6alkyl and the C1-C6alkyl moiety is straight or branched. | 08/16/2005 |
| 6919458 | Process for production of piperidine derivatives The present invention relates to a process for preparing piperidine derivative compounds of the formulae: wherein n is 0 or 1; R1 is hydrogen or hydroxy; ... | 07/19/2005 |
| 6902859 | Chemically amplified resist composition and method for forming patterned film using same A chemically amplified resist composition which comprises a base resin reacting in the presence of an acid, a photo acid generator generating an acid upon exposure, and a compound having the combination of an acetal moiety and a site which is eliminated by an acid i... | 06/07/2005 |
| 6890520 | Thermally stable ferulic acid derivatives A ferulic acid derivative represented by the general formula (1); a process for preparing a ferulic acid derivative represented by the general formula (1), comprising reacting ferulic acid or an ester thereof represented by the general formula (2) with a dihalometha... | 05/10/2005 |
| 6802874 | Linear compounds containing phenol and salicylic acid units The invention disclosed herein relates to linear compounds in the form of oligomers or polymers containing unsubstituted or substituted phenol units and unsubstituted or substituted salicylic acid units. These compounds are useful as additives for lubricants and fue... | 10/12/2004 |
| 6803480 | Diphenylmethane derivatives The invention relates to novel diphenylmethane derivatives, processes for their preparation and their use in medicaments, in particular for the indications of arteriosclerosis and hypercholesterolaemia. ... | 10/12/2004 |
| 6800658 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell prolifera... | 10/05/2004 |
| 6703421 | Methods of using phenylmethylbenzoquinone and hydroquinone compounds for treatment of myocarditis, dilated cardiomyopathy and heart failure A method for prevention or treating myocarditis, dilated cardiomyopathy and heart failure comprising administering to a patient in need of such treatment a NF-.kappa.B inhibitor in a therapeutically effective amount, wherein said NF-.kappa.B inhibitor is ... | 03/09/2004 |
| 6677474 | Difunctional IDBM and related compounds as novel dentin bonding agents Novel unsaturated esters for use in dentistry as bonding agents are produced by a reaction of a cyclic dianhydride with unsaturated alcohols. The novel unsaturated ester products have the formula: ##STR1## wherein R2 is H or CH3.... | 01/13/2004 |
| 6677465 | Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters The invention relates to a process for the enantioselective preparation of glycide ester (I) by (a) dihydroxylation of a corresponding 3-phenyl cinnamate (II) by osmium (VIII) oxide catalysis in the presence of a Sharpless ligand and an oxidizing agen... | 01/13/2004 |
| 6667415 | Tertiary butyl 4,4-bis(4'-hydroxyphenyl) pentanoate derivatives and positive resist materials containing the same Disclosed are novel tert-butyl 4,4-bis(4'-hydroxyphenyl)pentanoate derivatives represented by the following general formula (I); ##STR1## wherein R1 represents a protective group which can be readily eliminated under an acidic condition, and R | 12/23/2003 |
| 6664380 | Perfluorosulfonylmethide compounds; use thereof for carbon-carbon bond formation Free perfluorosulfonylmethide compounds and metal salts thereof show strong catalytic activity in carbon-carbon bond formation reactions, in amounts as low as 0.1 mole %. Fluorous media may be used, especially biphasic fluorous media enabling ready recycl... | 12/16/2003 |
| 6646152 | Method of producing 2-hydroxycarboxylic acid esters A process for preparing 2-hydroxycarboxylic esters having a quaternary ଲ-carbon atom by reaction of glycidyl esters with an organoaluminum reagent is described.... | 11/11/2003 |
| 6596038 | Linear compounds containing phenol and salicylic acid units The invention disclosed herein relates to linear compounds in the form of oligomers or polymers containing unsubstituted or substituted phenol units and unsubstituted or substituted salicylic acid units. These compounds are useful as additives for lubrica... | 07/22/2003 |
| 6569897 | Alkenyldiarylmethane non-nucleoside HIV-1 reverse transcriptase inhibitors Alkenyldiarylmethane (ADAM) compounds have been found effective as anti-HIV agents. Novel ADAM compounds, their pharmaceutical formulations and a method of using same to treat viral infections are described.... | 05/27/2003 |
| 6455585 | Esters derived from substituted phennyl-cyclohexyl compounds New esters derived from substituted phenyl-cyclohexyl compounds, which are derived from Tramadol, process for obtaining them and their use for preparing a drug with analgesic properties. These new compounds of general formula (I) have a higher analgesic a... | 09/24/2002 |
| 6358431 | Calixarenes A method of imparting a water repellent surface to a hydrophilic substrate which comprises contacting the substrate with a solution or dispersion of a suitable calixarene in a liquid medium.... | 03/19/2002 |
| 6291689 | Method for the preparation of citalopram A method for the preparation of citalopram is described comprising reduction of the oxo group of a compound of formula (IV), ##STR1## wherein R1 is CN, C1-6 alkyloxycarbonyl or C1-6 alkylaminocarbonyl, ring closure of the ... | 09/18/2001 |
| 6288265 | Phloroglucidic acid and derivatives as antibacterial agents A series of phloroglucide derivatives are synthesized, which possess potent antibacterial activities. They include unsymmetrical phloroglucide analogs, phloroglucides attached to cephalosporins at the C-3' position, and 7-(phloroglucidamido)cephalosporins... | 09/11/2001 |
| 6235923 | Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity.... | 05/22/2001 |
| 6225494 | Trisubstituted phenyl derivatives having retinoid agonist or inverse agonist type biological activity Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity.... | 05/01/2001 |
| 6207852 | Smooth muscle spasmolytic agents, compositions and methods of use thereof The present invention relates to smooth muscle spasmolytic agents, pharmaceutical compositions containing them and method of using said compounds and compositions for the treatment of urinary incontinence, gastric hyperactivity (ex. Irritable Bowel Syndro... | 03/27/2001 |
| 6140529 | Synthesis of optically active cyclohexylphenylglycolate esters A process for the preparation of optically active cyclohexylphenylglycolate esters is described. The process utilizes carboxylic acid activation to couple (R)- or (S)-cyclohexylphenylglycolic acid (CHPGA) with 4-N,N-diethylamino butynol or other propargyl... | 10/31/2000 |
| 6121255 | Phloroglucide derivatives and their pharmceutical use A phloroglucide derivative having the following formula: ##STR1## wherein Q is halogen; X is CH2 or C.dbd.O; Y is cephalosporin having a formula of ##STR2## wherein Ph is phenyl, Ac is acetoxy, or pharmaceutically acceptable salts ... | 09/19/2000 |
| 6107517 | Thyroid hormone analogues and methods for their preparation Thyroid hormone analogues are disclosed. Methods of using such analogues and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.... | 08/22/2000 |
| 6103762 | Bi-aromatic compounds and pharmaceutical and cosmetic compositions containing same The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R1 is --CH3, --CH2 --O--R6, --OR6 or --COR7 ; R2 is --OR8, --SR... | 08/15/2000 |
| 6043247 | Modulators of molecules with phosphotyrosine recognition units The present invention relates to novel substituted acrylic acids, to methods for their preparation, compositions containing them, and their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to... | 03/28/2000 |
| 6037488 | Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity.... | 03/14/2000 |
| 6005125 | Universal allyl linker for solid-phase nucleic acid synthesis A universal linker for solid-phase nucleic acid synthesis that is cleaved under conditions orthogonal to those used during the synthesis and deprotection of nucleic acids such as dsDNA or RNA fragments is disclosed. The invention includes compounds of the... | 12/21/1999 |
