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| Number | Title | Issue Date |
| 7858819 | Tris(formylphenyl) and novel polynuclear phenol derived therefrom A new tris(formylphenyl) of the following general formula and polynuclear phenol derived therefrom: ... | 12/28/2010 |
| 7589228 | Fluorine-containing compound The present invention has an object to provide a fluorine-containing compound which can be used for applications such as additives making a transparent resin material low in a water absorbing ratio and high in water repellency without deteriorating of various proper... | 09/15/2009 |
| 7429669 | Therapeutic compounds Disclosed herein are compounds of the formula or salts or bioisosteres thereof. Therapeutic methods, medicaments, and compositions related thereto are also disclosed. ... | 09/30/2008 |
| 7393968 | Intermediates in producing phenoxyacetic acid derivatives and method of using the same The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has β3-adrenoceptor stimulating activity... | 07/01/2008 |
| 7368566 | Process and intermediates for preparing benzazepines Disclosed is a new process and intermediates for preparing benzazepines of Formula (I): wherein R1 and R2 are as defined herein. ... | 05/06/2008 |
| 7332622 | Process for preparing optically active nitro compounds and cyano compounds A process for preparing optically active nitro compounds and cyano compounds using a metal complex, which is obtained by reaction of an optically active nitrogen-containing compound and a periodic table group VIII metal complex, in the asymmetric Michael reaction. | 02/19/2008 |
| 7288624 | Inhibitors of interleukin-1β converting enzyme The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmace... | 10/30/2007 |
| 7267974 | Polyhydroxyalkanoate synthesizing microorganism and process of producing polyhydroxyalkanoate using the same Microorganisms showing higher productivity of unusual-polyhydroxyalkanoate (PHA) than ever by using an inexpensive substrate or under specific conditions are obtained from wild strains and mutant strains. The microorganisms are cultured with such substrates to synth... | 09/11/2007 |
| 7163959 | Prostagladin derivatives for the treatment of glaucoma or ocular hypertension The invention relates to ophthalmological compositions for topical treatment of glaucoma or ocular hypertension comprising an effective intraocular pressure reducing amount of a prostaglandin derivative of PGA, PGB, PGD, PGE or PGF, in which the omega chain contains... | 01/16/2007 |
| 7161022 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative A 4-phenyl-4-oxo-2-butenoate derivative is stably supplied in a short period of time, at low cost, in high purity and on an industrial scale by a process for producing the 4-phenyl-4-oxo-2-butenoate derivative, which comprises simultaneously or continuously reacting... | 01/09/2007 |
| 7135540 | Polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same The invention provides a polyhydroxyalkanoate having a bromo group in a unit and being thermally stable and capable of arbitrarily controlling physical properties, and a producing method thereof. According to the invention, there are provided a polyhydroxyalkanoate ... | 11/14/2006 |
| 7101906 | 2,3,4-substituted cyclopentanones as therapeutic agents Disclosed herein are compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, wherein a dashed line represents the presence or absence of a bond; ... | 09/05/2006 |
| 7056708 | Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule The present invention provides a method of effectively producing polyhydroxyalkanoate having an aromatic substituted residue in its monomer unit. In the method of producing polyhydroxyalkanoate by using microorganisms, microorganisms capable of producing polyhydroxy... | 06/06/2006 |
| 7015592 | Marking on underfill A marking is formed on an underfill between a die and a substrate. ... | 03/21/2006 |
| 6998423 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders includ... | 02/14/2006 |
| 6946269 | Alkyl esters of 3-(3,4-dihalophenyl)-2,6-dioxopiperidine-3-propionic acid of use as intermediates The invention relates to lower-alkyl esters of 3-(3,4-dihalophenyl)-2,6-dioxopiperidine-3-propionic acid derivatives, and to processes for preparing the same. ... | 09/20/2005 |
| 6939835 | Cyclic compounds and their use as precursors of fragrant alcohols Compounds of the formula in which the dotted lines indicate the position of single or double bonds, R1 represents a radical belonging to a fragrant alcohol of the formula R1OH, X represents a nucl... | 09/06/2005 |
| 6927300 | Process for the preparation of Latanoprost Disclosed is a process for the preparation of the anti-glaucoma drug Latanoprost, in good yield, in large amounts and with desired purity. Also disclosed are novel intermediates for the above process. ... | 08/09/2005 |
| 6911521 | Polyhydroxyalkanoate that comprises unit having substituted or unsubstituted (phenylmethyl) sulfanyl structure in side chain thereof and process for producing the same A polyhydroxyalkanoate that comprises a unit represented by the following chemical formula (1): wherein R1 is a substituent of an aromatic ring selected from the group consisting of H, CH3, C2H | 06/28/2005 |
| 6906113 | Surface-active photoinitiators Compounds of formula Ia, Ib and Ic, (Ic), in which R, R1 and R2 are e.g. phenyl, naphthyl, anthracyl, phenanthryl or a heterocyclic radical, are suitable as photoinitiators which accumulate at the surface of coatings. ... | 06/14/2005 |
| 6878718 | Phenylalanine enamide derivatives Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 | 04/12/2005 |
| 6861550 | Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same Microorganisms capable of producing novel polyalkanoates having 3-hydroxybenzoylalkanoic acids as monomer units by utilizing benzoylalkanoic acids as starting materials are cultured in media containing benzoylalkanoic acids and saccharides, and the polyhydroxyalkano... | 03/01/2005 |
| 6858747 | Process to prepare, 1,4-dihydropyridine intermediates and derivatives thereof An improved catalyst is disclosed for a process involving the preparation of benzylidene intermediates useful in the preparation of 1,4-dihydropyridine compounds and derivatives thereof useful as medicines such as for example felodipine. This is accomplished by the ... | 02/22/2005 |
| 6790979 | Curcumin analogues and uses thereof The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treat... | 09/14/2004 |
| 6670485 | Prostanoic acid derivatives as agents for lowering intraocular pressure The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; ... | 12/30/2003 |
| 6649172 | Amphipathic aldehydes and their uses as adjuvants and immunoeffectors This invention relates to novel aldehyde containing compounds and their uses as adjuvants and immunoeffectors.... | 11/18/2003 |
| 6639093 | Process for the preparation of hydroxybenzoic benzyl esters The invention relates to the preparation of hydroxybenzoic benzyl esters by reacting benzyl chloride with hydroxybenzoic acids in the presence of one or more amides.... | 10/28/2003 |
| 6635782 | Polyhydroxyalkanoate and manufacturing method thereof To provide a novel polyhydroxyalkanoate and a manufacturing method by a microorganism capable of substantially reducing unintended monomer units and obtaining the polyhydroxyalkanoate in a high yield. A microorganism capable of synthesizing a novel polyhy... | 10/21/2003 |
| 6593488 | 4-fluoro-3-oxocarboxylic esters and process for producing the same The present invention is to provide 4-fluoro-3-oxocarboxylates represented by the following formula (1): ##STR1## wherein R1 represents an alkyl group or an aryl group; R2 and R3 each represent a hydrogen atom or an alkyl group... | 07/15/2003 |
| 6590119 | Methods for the synthesis of dioxoalkanoic acid compounds The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.... | 07/08/2003 |
| 6586468 | ω-substituted phenyl-prostaglandin E derivatives and drugs containing the same as the active ingredient A ω-substituted phenyl-prostaglandin of formula (I), a process for the preparation thereof, a mediciament comprising it as active ingredient (all symbols have the same meaning as described in the specification). ##STR1## The compounds of the formula (I) ... | 07/01/2003 |
| 6576784 | Antiviral agents Novel antiviral (including antiretroviral) compounds are mono- or dicarboxylic acid esters of hypericin in which one or both of the methyl groups of hypericin are substituted by carboxylic acid ester groups of the formula COOR3 in which R3... | 06/10/2003 |
| 6555287 | Non-subliming, difunctionalized ultraviolet dyes for use in anti-reflective coatings An improved light attenuating compound for use in the production of microdevices is provided. Broadly, the light attenuating compound is difunctional and can be directly incorporated (either physically or chemically) into photolithographic compositions su... | 04/29/2003 |
| 6541655 | Catalytic compositions and methods for asymmetric allylic alkylation Complexes of a selected class of chiral ligands with molybdenum, tungsten or chromium, preferably molybdenum, are effective as catalysts in highly enantioselective and regioselective alkylation of allylic substrates.... | 04/01/2003 |
| 6509374 | Compounds, their preparation and use The present invention relates to compounds of the general formula I. The compounds are useful in the treatment of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 01/21/2003 |
| 6492550 | Alpha-substituted thio, -oxo trifluoromethylketones as phospholipase inhibitors Inhibitors of the cytosolic phospholypase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula ##STR1## where X, Z, X1, R1, ... | 12/10/2002 |
| 6469200 | Process for producing 2-alkylidene-4-bromoacetoacetic acid ester A process for producing a 2-alkylidene-4-bromoacetoacetic acid ester of the formula (3): ##STR1## wherein R1 and R2 each independently represent a lower alkyl group having 1-5 carbon atoms, the process is characterized by reacting a ... | 10/22/2002 |
| 6417389 | Process for the preparation of HPB esters This invention relates to a novel advantageous process for the stereoselective preparation of 2-hydroxy-4-phenylbutyrates (HPB esters) and of their precursors. This is done by starting from readily accessible -unsaturated -hydroxy-γ-keto es... | 07/09/2002 |
| 6380257 | Aromatic di-keto derivatives, processes for their production and their use as a pharmaceutical The present invention relates to new aromatic di-keto derivatives and to their pharmaceutically acceptable salts, esters, ethers and other chemical equivalents. The derivatives are glucose-6-phosphate translocase inhibitors and can be used in the treatmen... | 04/30/2002 |
| 6380249 | HIV integrase inhibitors Certain six-membered aromatic and heteroaromatic-dioxobutyric acid derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment ... | 04/30/2002 |
