Quotables
"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8163952 | RAR receptor agonist ligands and use thereof in human medicine and cosmetics The invention relates to compounds corresponding to general formula (I) below: to the compositions containing same, to methods for the preparation thereof and to the use thereof in pharmaceutical compositions for use in hum... | 04/24/2012 |
| 8106232 | 3-carboxypropyl-aminotetralin derivatives and related compounds as mu opioid receptor antagonists The invention provides 3-carboxypropyl-aminotetralin compounds of formula (I): wherein R1, R2, R3, R4, R5, and R6 are defined in the specification, or a phar... | 01/31/2012 |
| 8101791 | Aminotetralin compounds as mu opioid receptor antagonists The invention provides aminotetralin compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, n, and m are defined in the specification, or a... | 01/24/2012 |
| 7485742 | Non-glycosidic and non-peptidic inhibitors of selectin, and the use thereof A new class of non-glycosidic and non-peptidic inhibitors of selectins with low molecular weight according to the general formula 1 is described, as well as methods for their production. These compounds represent a new clas... | 02/03/2009 |
| 7365197 | Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines This invention relates to a method for the regioselective synthesis of 4,6,7,8-substituted benzo[g]quinoline-3-carbonitriles and 4,6,7,8-substituted benzo[g]quinazolines as well as intermediates thereof. The compounds derived from this invention are useful for the t... | 04/29/2008 |
| 7361785 | Compound protecting against ultraviolet rays An ultraviolet ray protection agent including a compound having an ultraviolet ray protection effect as an active ingredient. The compound is expressed by general formula I′: wherein X represents NH or O; Y′ represents ... | 04/22/2008 |
| 7332320 | Protease producing an altered immunogenic response and methods of making and using the same The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that encode novel variants, host cells comprising DNA encoding novel variants... | 02/19/2008 |
| 7317125 | Diacylglycerol acyltransferase inhibitors Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutica... | 01/08/2008 |
| 7259188 | Methods and pharmaceutical compositions for treatment of anti-estrogen resistant breast cancer using RXR modulators Methods and compositions for the treatment of anti-estrogen resistant breast cancer using retinoid compounds which are modulators of Retinoid X Receptors. ... | 08/21/2007 |
| 7199265 | Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds and to methods for using such compounds such as in the regulation of m... | 04/03/2007 |
| 7196220 | Bone targeting compounds for delivering agents to the bone for interaction therewith The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or disease to the b... | 03/27/2007 |
| 7125991 | Compounds derived from benzoic acid esters, composition containing said compounds and use thereof The invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 represents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 ... | 10/24/2006 |
| 7115662 | Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives Disclosed are the compounds of formula I wherein R is methyl or ethyl; R1 is chloro or fluoro; R2 is hydrogen or fluoro; R3 is hydrogen, fluoro, chloro, methyl, ethyl, methoxy, et... | 10/03/2006 |
| 7097789 | Thermoplastic containers exhibiting excellent protection to various ultraviolet susceptible compounds Novel thermoplastic articles that contain novel ultraviolet absorbing compounds that are liquid in nature, are extremely low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat any discoloring wi... | 08/29/2006 |
| 7094918 | Low-color ultraviolet absorbers for thermoplastic and thermoset high UV wavelength protection applications Novel ultraviolet absorbing compounds that are liquid in nature, are low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat such discoloring), and are highly effective in providing protection in... | 08/22/2006 |
| 7091242 | Beta-amino acid derivatives as integrin receptor antagonists The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment of inflammatory diseases.... | 08/15/2006 |
| 7091380 | N-biphenylmethyl aminocycloalkanecarboxamide derivatives N-Biphenyl(substituted methyl) aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway. ... | 08/15/2006 |
| 7078565 | Benzamide derivatives as antagonists of orexin receptors Disclosed are phenyl-alkylene benzamides useful as orexin antagonists ... | 07/18/2006 |
| 7057038 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer... | 06/06/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 6930200 | Multicomponent synthesis of amino acids and derivatives thereof Mono-substituted and di-substituted alpha-amino acids and derivatives thereof, substituted at the alpha positon with one (mono-) or two (di-) substituents (R2 and/or R3) as shown in Formula 1: N(R4R5)C(R2R3... | 08/16/2005 |
| 6900244 | Anilino liver X-receptor modulators The present invention is directed to selective LXR modulators, small molecule compounds corresponding to Formula I and is further directed to a process of treating a condition in a mammal that is modulated by LXR using a therapeutically effective dose of a compound ... | 05/31/2005 |
| 6897333 | Process for the preparation of fibrates A process for the preparation of fibrates of formula I in which R1 is a halogen atom, a 2,2-dichloro-cyclopropyl group, a (4-chlorophenyul)-hydroxymethyl group, a-4-chlorobenzoyl group or a 2-(4-chlorobenzam... | 05/24/2005 |
| 6891072 | Process for production of dimers or aromatic monohydroxyl compounds The present invention provides a method for preparing dimer of a monohydroxy aromatic compound. In the method of the present invention, oxidative coupling reaction of a monohydroxy aromatic compound represented by formula [I]: Ar—OH [I] | 05/10/2005 |
| 6878723 | LTA4 hydrolase inhibitors The invention concerns compounds inhibiting LTA4 hydrolase of formula (I). The invention also concerns their therapeutic, in particular anti-inflammatory, applications. ... | 04/12/2005 |
| 6849742 | Binaphthol derivative and process for producing the same The present invention provides a binaphthol compound represented by formula [1]: and a salt thereof. The binaphthol compound of the present invention is useful for manufacturing antiseptic compounds or chiral catalysts... | 02/01/2005 |
| 6844003 | Compounds derived from benzoic acid esters, composition containing said compounds and use thereof The invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 presents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 or... | 01/18/2005 |
| 6831102 | Phenyl naphthol ligands for thyroid hormone receptor New thyroid receptor ligands are provided which have the general formula I: wherein R1 is halogen, trifluoromethyl, substituted or unsubstituted aryl, substituted or... | 12/14/2004 |
| 6777442 | Diphenyl derivatives The present invention relates to compounds of the general formula (I) in which X represents O, S, SO, SO2, CH2, CHF, CF2 or NR8, and Z represents a group of the formula | 08/17/2004 |
| 6774116 | Prodrugs via acylation with cinnamate A prodrug composition containing a cinnamate moiety and a biologically active molecule moiety which can be released by hydrolysis or activated by light is disclosed. The cinnamate moiety can have substituents of various electronically donating or electronically with... | 08/10/2004 |
| 6743914 | Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer... | 06/01/2004 |
| 6727281 | Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives Disclosed are the compounds of formula I wherein R is methyl or ethyl; R1 is chloro or fluoro; R2 is hydrogen or fluoro; R3 is hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy or ... | 04/27/2004 |
| 6699904 | PPAR agonists PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-c... | 03/02/2004 |
| 6667413 | Uracil compounds and use thereof The present invention relates to an uracil compound of the formula [I]: ##STR1## wherein W represents oxygen, sulfur, imino or C1 to C3 alkylimino; Y represents oxygen, sulfur, imino or C1 to C3 alkylimino; R | 12/23/2003 |
| 6664291 | Malonamic acids and derivatives thereof as thyroid receptor ligands The present invention relates to novel thyroid receptor ligands and, more particularly, relates to malonamic acids and derivatives thereof of Formula I, which are useful in the treatment of obesity, overweight condition, hyperlipidemia, glaucoma, cardiac ... | 12/16/2003 |
| 6649656 | Anthranilic acid derivatives The present invention relates to an anthranilic acid derivative expressed by the following formula (1) or the following formula (2), or its pharmacologically permissible salt or solvate. ##STR1##... | 11/18/2003 |
| 6624184 | Amide and diamide inhibitors of IMPDH enzyme for use in treating IMPDH-associated disorders The present invention discloses the identification of the inhibitors of IMPDH (inosine-5'-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as... | 09/23/2003 |
| 6610710 | Phenylalanine derivatives Phenylalanine derivatives of the following formula and analogues thereof have an antagonistic activity to 댔댧 integrin and a selectivity toward 댔댡 integrin. They are used as therapeutic agents for various diseases to which ... | 08/26/2003 |
| 6605742 | Cyclo azaphospha hydrocarbons Novel cyclo azaphospha hydrocarbons according to formula I ##STR1## are provided. The compounds are useful as metalloprotease inhibitors.... | 08/12/2003 |
| 6590119 | Methods for the synthesis of dioxoalkanoic acid compounds The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.... | 07/08/2003 |
