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| Number | Title | Issue Date |
| 7321053 | Process for the manufacture of tocyl and tocopheryl acylates A process for the manufacture of a tocyl acylate or a tocopheryl acylate comprises reacting tocol or a tocopherol with an acylating agent in the presence of a solid heterogeneous Brönsted acid catalyst, said catalyst being an inorganic Brönsted acid on a solid car... | 01/22/2008 |
| 7288676 | Arylphenyl-substituted cyclic ketoenols The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulph... | 10/30/2007 |
| 7271297 | Process for producing vinyl ether compounds A process produces vinyl ether compounds and includes allowing a vinyl ester compound represented by following Formula (1): wherein R1, R2, R3 and R4 are the same or di... | 09/18/2007 |
| 7268160 | Remedies The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor producti... | 09/11/2007 |
| 7250528 | Process for producing indenol esters or ethers The present invention relates to a process for making indenol esters or ethers from an α-substituted cinnamic aldehyde derivative such as an acetal or an acylal. Said reaction is promoted by the use of strong mineral acids, sulphonic acids, acidic zeolites or Lewis... | 07/31/2007 |
| 7249907 | Spring loaded turnbuckle with quick disconnect A spring loaded tensioning device. The device includes an elongated tubular member containing a spring loaded rod which extends through a lower stop on the tubular member to an attachment feature such as a hook. At the upper end of the tubular member, a pivot housin... | 07/31/2007 |
| 7227043 | 2-phenyl-2-substituted-1,3-diketones The invention relates to novel phenyl-substituted cyclopentane- and cyclohexane-1,3-dione derivatives of the formula (I) in which W, X, Y, Z, A, B, Q1, Q2, Q3 | 06/05/2007 |
| 7166726 | Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity Disclosed herein are compounds of the formula wherein R1 is independently H or alkyl of 1 to 6 carbons; R2 is optional and is defined as lower alkyl of 1 to 6 carbons, F, Cl, Br... | 01/23/2007 |
| 7105471 | Arylphenyl-substituted cyclic ketoenols The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulph... | 09/12/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 6942980 | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities Methods of characterizing and identifying negative hormones of nuclear receptors. Also disclosed are methods of making modulators of retinoid nuclear receptor transactivation activity, assays for agonists, antagonists, and negative hormones of the RAR receptor, and ... | 09/13/2005 |
| 6872748 | Simplified resiniferatoxin analogues as vanilloid receptor agonist showing excellent analgesic activity and the pharmaceutical compositions containing the same The present invention is related to new vanilloid analogues containing resiniferatoxin pharmacophores, pharmaceutical compositions that have such analogues, and their uses as vanilloid receptor agonists and potent analgesics. The present invention provides a pharmac... | 03/29/2005 |
| 6869974 | Pharmaceutical compounds Compounds or their salts having general formulas (I) and (II): wherein s is an integer equal to 1 or 2, A is the radical of a drug that satisfies certain pharmacological tests, C and C1 are bivalent radicals, and precursors of the radicals B and B1 | 03/22/2005 |
| 6767923 | Benzhydryl derivatives Benzhydryl derivatives of the formula I, where the index and the variables are as defined below: X is oxygen or sulfur; R1, R3 are halogen, cyano, nitro, hydroxyl, mercapto, amino, alk... | 07/27/2004 |
| 6713464 | Derivatives of 3,3-diphenylpropylamines The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs. More particularly, the invention relates to novel prodr... | 03/30/2004 |
| 6709642 | Calixarene acetamido derivatives, preparation and use thereof for extracting strontium The invention concerns derivatives of calixarene having the formula: in which: R1 represents various hydrocarbon groups, R2 and R3 represent an alkyl, cycloalkyl or aryl gro... | 03/23/2004 |
| 6656968 | (Z)-styryl acetoxyphenyl sulfides as cyclooxygenase inhibitors Compounds of the formula ##STR1## are provided wherein R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen, halogen, hydroxyl, C1 -C8 alkyl, C1 -C | 12/02/2003 |
| 6613806 | Enhancement of the efficacy of benzoylbenzenes The invention relates to method for the enhancement of the activity and/or systemicity of fungicidal compositions containing at least one benzoylbenzene of formula I ##STR1## wherein R1 through R7, m and n are as defined in claim... | 09/02/2003 |
| 6552213 | Stereoselective route to produce tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, an intermediate in the synthesis of trans-resveratrol The present invention relates to a new stereoselective method for the preparation of tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene derivative of the formula (I) which is a key intermediate in the synthesis of trans-resverat... | 04/22/2003 |
| 6383499 | Topical medicament for the treatment of psoriasis A topical medicament for the treatment of psoriasis comprises metallic iodine, virgin wax, a variety of oils of animal and plant origin, camphor, chlorophyll and benzoic acid in a pharmaceutically acceptable emollient excipient base.... | 05/07/2002 |
| 6297399 | Indane compounds with smooth muscle relaxing and/or mast cell stabilizing and/or anti-inflammatory activity Indane compounds of general formulas (7) and (8) and their pharmaceutical use particularly to achieve smooth muscle relaxing activity and/or mast cell stabilizing activity and/or anti-inflammatory activity as described, wherein in formula (7) R2 | 10/02/2001 |
| 6162445 | Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (I): in which X is one of the radicals: ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary,... | 12/19/2000 |
| 6159988 | Arylcycloalkyl derivatives, their production and their use Compounds of formula I, ##STR1## and the physiologically tolerable salts thereof, wherein the substituents R1 -R4 have the meanings given in the specifications and show an activity against inflammatory conditions.... | 12/12/2000 |
| 6143922 | Diols and unsaturated monomers The present invention relates to a novel composition of diols, said composition of diols comprising HO--(H3 C)R4 C--Q--CR5 (CH3)--OH wherein Q is a diaryl group comprising two aryl groups linked together directly (as... | 11/07/2000 |
| 6083986 | Potassium channel inhibitors Compounds useful as potassium channel inhibitors and especially useful for the treatment of cardiac arrhythmias and cell proliferative disorders are described.... | 07/04/2000 |
| 6080739 | Colchicine-skeleton compounds, their use as medicaments and compositions containing them The present invention relates to colchicine and thiocolchicine derivatives which can be obtained from these molecules by functionalization of the C-7 to ketone or functionalization of the amino group. Said compounds have a marked antiblastic activity both... | 06/27/2000 |
| 6046354 | Diacyloxy propanol derivatives A novel glycerol derivative, a process for preparing the same, and a process for preparing a triazole derivative. An optically active 2-arylglycerol derivative which is novel and useful as a synthetic intermediate of medicament is provided, and furthermor... | 04/04/2000 |
| 6040470 | Sulfonyl compound and thermalsensitive recording medium using the same There is provided a developer composition including at least one of sulfonyl compounds represented by formula (1) and at least one of sulfonyl compounds represented by formula 2: ##STR1## wherein X is H or lower alkyl, R1, R2, R... | 03/21/2000 |
| 6037059 | High molecular weight dibenzoylresorcinol UV absorbers, coating compositions, articles and method of making Novel dibenzoylresorcinol compositions capable of absorbing ultraviolet light having the formula ##STR1## where Ar1 and Ar2 are independently substituted or unsubstituted monocyclic or polycyclic aryl groups, R is hydrogen, an a... | 03/14/2000 |
| 6025328 | Antitumor agents The present invention provides illudin analogs of the general formula I: ##STR1## wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceuticall... | 02/15/2000 |
| 5942290 | Molecular complex compounds of acylphosphine oxide and -hydroxy ketones as photoinitiators Molecular complex compounds comprising a mono-, bis- or trisacylphosphine oxide compound with an -hydroxy ketone compound are suitable as photoinitiators for the photopolymerization of free-radically polymerizable compounds.... | 08/24/1999 |
| 5883235 | Calix4!arene compounds for detection of calcium Calix4!arene compounds are disclosed that can be used as active components in a calcium sensitive sensor. The compounds exhibit strong calcium ion binding selectivity over sodium and potassium ions and they are stable during sterilization.... | 03/16/1999 |
| 5874611 | Butenyl hydroquinone derivatives A hydroquinone derivative (I) represented by the following formula: ##STR1## wherein R1 is a hydrogen atom, acetyl group or benzoyl group, such hydroquinone derivative being useful as an intermediate for chroman derivatives useful as a blo... | 02/23/1999 |
| 5856490 | Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification have retinoid-like biological activity.... | 01/05/1999 |
| 5808137 | Chalcones and esters thereof with antiproliferative activity in uterus, ovary and breast tumors The present invention relates to the use of some natural or synthetic chalcones and the esters thereof with straight or branched aliphatic acids, saturated and unsaturated, containing up to 22 carbon atoms in the therapy and prevention of the uterus, ovar... | 09/15/1998 |
| 5789413 | Alkylated styrenes as prodrugs to COX-2 inhibitors The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases c... | 08/04/1998 |
| 5763719 | Thermally stable fullerene derivatives and process for producing the same A fullerene derivative of the formula I ##STR1## where the symbols and indices have the following meanings: F is a fullerene radical of the formula (C20+2m), where m is a number from 1 to 50 R1 to R8 are identical or ... | 06/09/1998 |
| 5705659 | Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof Intermediate compounds represented as formula (I) useful for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof are disclosed. ##STR1## wherein R is tetrahydropyranyl, tetrahydrofuranyl, 2-ethoxyethyl, t-b... | 01/06/1998 |
| 5693251 | Optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements An optically active phenol useful in the preparation of liquid crystalline compounds which is represented by the formula (V): ##STR1## wherein R2 represents an alkyl or alkoxyalkyl group having 1 to 20 carbon atoms optionally substituted b... | 12/02/1997 |
| 5684198 | Method of preparing therapeutic amides Amides having formula I: ##STR1## wherein E, X, R2 and R3 have the meanings given in the specification, and pharmaceutically acceptable salts and pharmaceutically acceptable in vivo hydrolysable esters thereof, which are useful ... | 11/04/1997 |
