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| Number | Title | Issue Date |
| 7858821 | Intermediate compounds useful to prepare dolasetron The present invention relates to intermediates useful in the synthesis of Dolasetron and synthetic precursors thereof, as well as to processes for obtaining them. In addition, it refers to the hydrochloric salt of Dolasetron and polymorphic forms of Dolasetron and p... | 12/28/2010 |
| 7531688 | Method for recovering unreacted alcohol from biodiesel product streams by flash purification A method for making fatty acid esters by reacting triglycerides with an excess of alcohol in a pressurized environment, where the unreacted alcohol component is separated from the reaction product by a flash purification techniques. In this manner, the pressure of t... | 05/12/2009 |
| 7416865 | Process for the preparation of dihydroxy esters and derivatives thereof A process is provided for the preparation of a compound of formula (1) wherein R and R′ represent optionally substituted hydrocarbyl groups and X represents a hydrocarbyl linking group. The process comprises either the st... | 08/26/2008 |
| 7338579 | Dewatering process A formaldehyde-containing product is separated from a formalin solution containing formaldehyde, water, and methanol by distilling in the presence of a water entraining compound, especially methyl propionate or methyl methacrylate. The product contains substantially... | 03/04/2008 |
| 7321059 | Compounds for use as surfactants Compounds of formula (I): or salts or solvate thereof, wherein: n and N independently represent an integer 2 to 12; m1 and m2 independently represent an integer 1 t... | 01/22/2008 |
| 7186272 | Condensation products of hydroxycarboxylic acids and glycols or glycerol The invention relates to reaction products of glycols, diglycols, higher glycols or glycerol with α-hydroxycarboxylic acids in a molar ratio of 1:2 or higher, especially conforming to the general formula (V) where R is hydrogen or a C1-3 alkyl group, pre... | 03/06/2007 |
| 7169950 | Method for producing monocarbonyl compounds or biscarbonyl compounds or hydroxyl compounds The invention relates to a method for producing monocarbonyl compounds or biscarbonyl compounds or hydroxyl compounds by ozonizing, unsaturated organic carbon compounds that, per molecule, have one or more olefinic or aromatic double bonds, which can be cleaved by o... | 01/30/2007 |
| 7157255 | Process for the preparation of dihydroxy esters and derivatives thereof A process is provided for the preparation of a compound of formula (1) wherein R and R′ represent optionally substituted hydrocarbyl groups and X represents a hydrocarbyl linking group. The process comprises ei... | 01/02/2007 |
| 7091375 | Method for the production of 2=-keto-l-gulonic acid CCalkyl esters The invention relates to a method for producing 2-keto-L-gulonic acid-C4–C10 alkyl ester by esterifying 2-keto-L-gulonic acid (KGS) with an unsaturated, branched or unbranched C4–C10 alcohol. The inventive method is ch... | 08/15/2006 |
| 6956018 | Polyoxyalkylene monoalkyl ether, process for producing the same, polymerizable polyoxyalkylene monoalkyl ether derivative, polymer of said derivative and dispersant comprising said polymer A polymerizable polyoxyalkylene monoalkyl ether derivative prepared by using a polyoxyalklene monoalkyl ether which gives, in gel permeation chromatography, a chromatogram which satisfies a relation expressed by an equation: S1/S0≦0.15, where... | 10/18/2005 |
| 6867321 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof The present invention provides a method for producing compound (XIV) useful as an intermediate for pharmaceutical agents efficiently and economically on an industrial scale without using ozone oxidation and highly toxic reagent, and an intermediate used for this met... | 03/15/2005 |
| 6825377 | Method for the dihydroxylation of olefins using transition metal catalysts This invention relates to process for dihydroxylation of olefins using transition metal catalysts to obtain monofunctional, bifunctional, and/or polyfunctional 1,2-diols of the formula (I) R1R2C(OH)—C(OH)R3R4â€... | 11/30/2004 |
| 6812368 | Diastereoselective hydrogenation of 1,3-hydroxyketones The invention relates to a novel process of diastereoselective hydrogenation of 1,3-hydroxyketones of formula (I) wherein R, R′ and R″ are as defined in claim 1 which is carried out in a solvent in the prese... | 11/02/2004 |
| 6667340 | Inhibitors of phosphatidyl myo-inositol cycle The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as ant... | 12/23/2003 |
| 6649786 | Ester-forming addition reaction product This invention provides a process to produce a hydroxyl group-containing ester-forming addition reaction product having an acid value of 20 mgKOH/g or less, which process is characterized in that 2,2-dimethylolalkanoic acid having 6 to 8 carbon atoms is m... | 11/18/2003 |
| 6620964 | Preparation of dihydroxycarboxylic esters in the absence of solvents A description is given of a process for preparing dihydroxycarboxylic esters and of an overall process for preparing R-(+)--lipoic acid.... | 09/16/2003 |
| 6610892 | Process for preparing 2,7-dimethyl-2,4,6-octatrienal monoacetals The invention relates to a process for preparing 2,7-dimethyl-2,4,6-octatrienal monoacetals of the general formula I ##STR1## which comprises a) condensing an ester phosphonium salt of the general formula II or an ester phosphonate of the general form... | 08/26/2003 |
| 6608230 | Single-stage method for producing -hydroxy ethers by oxidizing C=C unsaturated compounds with hydroperoxides A single-stage method for producing -hydroxy ethers by oxidizing olefinic substrates with organic hydroperoxides and opening the resultant oxirane ring by means of monovalent or polyvalent alcohols wherein a molybdenum compound in combination with ... | 08/19/2003 |
| 6573400 | Preparation of 2-keto-L-gulonic esters C1 -C10 -alkyl 2-keto-L-gulonates are prepared by esterifying 2-keto-L-gulonic acid or diacetone-2-keto-L-gulonic acid with a C1 -C10 -alcohol in the presence of an acidic catalyst by a process in which the este... | 06/03/2003 |
| 6462206 | Catalytic reduction of ketones and aldehydes using organometallic ruthenium complexes Ketones and aldehydes are hydrogenated to the corresponding alcohol or alkyl group, using H2 gas as the stoichiometric reductant, and organometallic ruthenium complexes as the catalysts.... | 10/08/2002 |
| 6452042 | Substituted propenoates and processes for the preparation thereof Substituted propenoates are prepared by eliminating an alcohol from a substituted malondialdehyde acetal, optionally in the presence of a homogeneous or heterogeneous catalyst.... | 09/17/2002 |
| 6407265 | Tin polyoxaalkanecarboxylates and compositions containing them Tin polyaalkanecarboxylates having the formula [(R1p R2q Sn)r Os ]t wherein R1 represents C1 -C6 alkyl, branched or straight, substituted or not by on... | 06/18/2002 |
| 6395920 | Process for preparing substituted acetals of malondialdehyde A process directed to the preparation of 2-substituted and 2,2-disubstituted acetals of malondialdehyde from ortho formates and substituted vinyl ethers in the presence of an acidic catalyst.... | 05/28/2002 |
| 6380439 | Single-stage method for producing -hydroxy ethers by oxidizing C=C-unsaturated compounds with hydroperoxides A single-stage method for producing -hydroxy ethers by oxidizing olefinic substrates with organic hydroperoxides and opening the resultant oxirane ring by means of monovalent or polyvalent alcohols wherein a molybdenum compound in combination with ... | 04/30/2002 |
| 6359168 | Compounds derived from menthol and use as refreshing agent Compounds of formula (I) ##STR1## in which R=H or CH3 and n is a whole number from 1 to 4. These compounds are useful as refreshing agents in various compositions, articles or products from flavor manufacture or perfumery.... | 03/19/2002 |
| 6329542 | Preparation of (S)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes The glycinamide of the formula ##STR1## is reacted with the dioxolane of the formula ##STR2## wherein L is a leaving group such as iodo, bromo, alkylsulfonyloxy, or arylsulfonyloxy to give the dioxolane of the formula ##STR3## Treating the dioxolane ... | 12/11/2001 |
| 6297396 | Method of crystallizing and purifying alkyl gallates A method for synthesizing alkyl gallates. Gallic acid and an alkyl alcohol of the order of the desired gallate are heated in a reaction vessel in the presence of a catalyst such as sulfuric acid or para-toluene sulfonic acid. Water is generated, forming a... | 10/02/2001 |
| 6288272 | Continuous process for preparing optically pure (s)-3,4-dihydroxybutyric acid derivatives The present invention relates to a continuous process for preparing optically pure (S)-3,4-dihydroxybutyric acid derivatives expressed by the following Formula 1 and more particularly, to the continuous process which enables preparing optically pure (S)-3... | 09/11/2001 |
| 6184376 | Synthesis of acyclic nucleoside derivatives Methods and novel intermediates of the formula: ##STR1## wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are --CH2 CH2 --, --CH2 CH2 CH2 | 02/06/2001 |
| 6043389 | Hydroxy and ether-containing oxyalkylene esters and uses thereof This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating cutaneous ulcers, treating gastrointestinal disorders, treating b... | 03/28/2000 |
| 6037489 | Method of purifying glyoxylic esters and distillation equipment for purifying glyoxylic esters A method for purifying glyoxylates includes (1) a coarse distillation process in which a crude glyoxylate in which water coexists is, in a film form, continuously subjected to coarse distillation, and (2) an azeotropic dehydration process in which the cru... | 03/14/2000 |
| 5997610 | Amphiphilic compounds with at least two hydrophilic and at least two hydrophobic groups based on dicarboxylic acid diamides The invention concerns amphiphilic compounds of general formula (I) ##STR1## with at least two hydrophilic and at least two hydrophobic groups based on diacarboxylic acid diamides. The amphiphilic compounds according to the invention are mostly surfa... | 12/07/1999 |
| 5965119 | Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of the formula: ##STR1## wherein: B is a leaving group or a residue of an amine-containing target moiety; G ... | 10/12/1999 |
| 5939580 | Process for preparing glyoxylic esters and their hydrates Process for preparing glyoxylic esters or their hydrates in which a water-soluble salt of a maleic or fumaric monoester or a mixture thereof is reacted with ozone in aqueous solution at temperatures of from 0 to 50° C., and the corresponding glyoxylic es... | 08/17/1999 |
| 5928393 | Fuel additive A fuel additive which comprises a compound selected from a novel amine, oxygen-containing and nitrogen-containing compounds having selected structures. The inventive additive when blended with a gasoline serves to suppress sludge or deposits in fuel intak... | 07/27/1999 |
| 5902895 | Method for the continuous production of esters of thermally unstable acids A method for the continuous production of esters of thermally unstable acids by the esterification, with or without a catalyst, of the acids with alcohols is provided. The method involves esterification at temperatures of approximately 80° C. to approxim... | 05/11/1999 |
| 5877334 | Intermediates useful in solid phase synthesis method A solid phase synthesis method and intermediates useful in the process are disclosed for the preparation of diamino diol and diamino alcohol inhibitors of HIV protease.... | 03/02/1999 |
| 5866606 | Nutritional formulations containing water-miscible lipid derivatives as anti-microbial agents A nutritional formulation containing an amount of diacetyltartaric acid esters of mono- and diglycerides effective to inhibit the infectious activity of pathogenic microorganisms is provided. A process of inhibiting the infectious activity of pathogenic m... | 02/02/1999 |
| 5808107 | Process for the preparation of hydroxy substituted gamma butyrolactones Preparation of 4-hydroxy substituted butyrolactones is described. A process for the preparation of 3-hydroxybutyrolactone, 1,2,4-trihydroxybutane and 3,4-dihydroxy acid methyl ester from malic acid is particularly described. The preparation of 4-hydroxyme... | 09/15/1998 |
| 5792876 | Process for producing acetals A process is described for producing acetals comprising reacting an aldehyde or a ketone with an alcohol in the presence of a titanium compound having an acetylacetone as a ligand, or in the presence of a compound selected from the group consisting of sta... | 08/11/1998 |