Class 560/143 - Salicylic acid or functional derivative

Subclass of Class 560 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the phenolic moiety is salicyclic acid,
No. of patents: 37
Last issue date: 06/23/2009

Number	Title	Issue Date
7550624	Pharmaceutically active salts and esters of 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol and 3- (3-dimethylamino-1-ethyl-1-hydroxy-2-methylpropyl)-phenol and methods of using same Pharmaceutically active salts and esters of 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol and 3-(3-dimethylamino-1-ethyl-1-hydroxy-2-methylpropyl)-phenol, and methods of using the same for treating or inhibiting increased urinary urgency or urinary inconti...	06/23/2009
6790978	Thyromimetic organic compounds Compounds of the present invention of the formula are thyromimetic agents which can be used to prevent and/or treat diseases associated with an imbalance of thyroid hormones, such as hypo- and hyper-thyroidism, obesity, ...	09/14/2004
6747003	Modified vitamin K-dependent polypeptides The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described. ...	06/08/2004
6689896	Thyromimetic organic compounds Compounds of the formula ##STR1## in which W is O, S, S(O) or S(O)2 ; X is --SR4, --S(O)R4, or --S(O)2 R4, --S(O)2 NR5R6; or X is --C(O)NR5R6 provided that --C(O)NR5R6 is located at the 3', 4' or 5' position; Y is O or H	02/10/2004
6599942	Thyromimetic organic compounds Compounds of the formula ##STR1## in which W is O, S, S(O) or S(O)2 ; X is --SR4, --S(O)R4, or --S(O)2 R4, --S(O)2 NR5R6; or X is --C(O)NR5R6 provided that --C(O)NR5R6 is located at the 3', 4' or 5' position; Y is O or H	07/29/2003
6566394	Salicylamide derivatives Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) an...	05/20/2003
6545018	Oxamic acids and derivatives as thyroid receptor ligands The present invention provides novel compounds of the Formula ##STR1## and prodrugs thereof, geometric and optical isomers thereof, and pharmaceutically acceptable salts of such compounds, prodrugs and isomers, wherein R1 -R8 and W a...	04/08/2003
6512137	Synthesis method of nitroxymethylphenyl esters of aspirin derivatives The invention describes a method for the synthesis of nitroxymethylphenyl esters of aspirin derivatives....	01/28/2003
6436916	Ibuprofen-aspirin and hydroxymethylacylfulvene analogs Ibuprofen-aspirin compounds useful in treating aspirin or ibuprofen-treatable conditions and hydroxymethylacylfulvene analogs useful as antitumor drugs....	08/20/2002
6326398	Oxamic acids and derivatives as thyroid receptor ligands The present invention provides novel compounds of the Formula ##STR1## and prodrugs thereof, geometric and optical isomers thereof, and pharmaceutically acceptable salts of such compounds, prodrugs and isomers, wherein R1 -R8 and W a...	12/04/2001
6278014	Synthetic procedure for the manufacture of aspirin The present invention provides a method for the synthesis of acetyl salicylic acid comprising mixing acetic anhydride and salicylic acid in approximately or exactly stoichiometric proportions and calcium oxide or zinc oxide, obtaining a yield of a mixture...	08/21/2001
6255277	Localized use of nitric oxide-adducts to prevent internal tissue damage A method for preventing adverse effects associated with the use of a medical device in a patient by introducing into the patient a device of which at least a portion includes a prophylactic or therapeutic amount of a nitric oxide adduct. The nitric oxide ...	07/03/2001
6077970	Carboxylic acid esters of 2-hydroxy-5-isoalkyl-beta-methylstyrene The present invention relates to carboxylic acid esters of 2-hydroxy-5-isoalkyl-beta-methylstyrenes wherein the said isoalkyl substituent comprises 8-18 carbon atoms....	06/20/2000
6037338	Method for treating aspirin-treatable cancers The present invention relates to a biodegradable plastic made from a combination of at least one synthetic plastic polymer, at least one natural polymer and a natural polymer attacking agent and articles made therefrom. The present invention further relat...	03/14/2000
5985927	Medicaments for the selective treatment of tumor tissues Medicinal products for the selective control of tumor tissue and a method for control of such tumor tissue by administration of such product to a host. The products comprise: (a) two different compounds having a pH below 7 when the compounds are present i...	11/16/1999
5973072	Polymeric vehicles which include a phenolic urethane reactive diluent The present invention is directed to a polymeric vehicle, the formulated coating composition and a coating binder made from the polymeric vehicle and a method for making the polymeric vehicle where the polymeric vehicle includes a phenolic urethane reacti...	10/26/1999
5760261	Higher fatty acid derivatives of salicylic acid and salts thereof The present invention also relates to a method of treating aspirin-treatable conditions comprising administering to a patient in need of such treatment a compound of Formula I ##STR1##...	06/02/1998
5703073	Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs Nonsteroidal antiinflammatory drugs which have been substituted with a nitrogen monoxide group; compositions comprising (i) a nonsteroidal antiinflammatory drug, which can optionally be substituted with a nitrogen monoxide group and (ii) a compound that d...	12/30/1997
5599974	Aldehydic agents for allosteric modification of hemoglobin Chemical compounds which interact inside the central water cavity of hemoglobin and bridge between the two ଱ subunits can be used to allosterically modify hemoglobin towards tense and relaxed states. The functional groups employed are aldehydes and ...	02/04/1997
5599959	Analogues of acetylsalicylic acid and novel uses thereof The present invention provides a salicylate analogue having the structure ##STR1## wherein R is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl; pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, ...	02/04/1997
5498729	Prodrug compositions Compositions degrading by hydrolysis to release a bioactive compound having carboxylic acid moieties, which are organic acid anhydrides having the following formula: ##STR1## wherein R' is a residue of a therapeutic bioactive compound, for example, ...	03/12/1996
5136084	Process for the acetylation of a mono-substituted phenol or a mono-substituted naphthol A novel process for the acetylation of a mono-substituted phenol or a mono-substituted naphthol is disclosed which comprises reacting the said mono-substituted phenol or the said mono-substituted naphthol respectively with vinyl acetate at a temperature o...	08/04/1992
5041615	Preparation of bis(salicyl) diesters Bis(salicyl) diesters useful as cross-linking agents for hemoglobin are prepared in high yield and purity by reacting salicylic acid or a derivative thereof with a lower aliphatic dicarboxylic acid halide in a lower aliphatic ketone or nitrile solvent in ...	08/20/1991
4908111	Process for the preparation of 7-(2-diethylaminoethyl)-theophylline acetyl salicylate and use thereof A process for the preparation of 7-(2-diethylaminoethyl)-theophylline acetylsalicylate and use of the product obtained. The process comprises prior filtering of a solution of the reactants through a layer of diatomaceous earth and activated carbon, coolin...	03/13/1990
4849417	Acetylsalicylic acid derivative and pharmaceutical composition thereof The hydrated complex of magnesium acetylsalicylate and urea of formula ##STR1## possesses exceptional analgesic and antipyretic properties. It may be crystallized from a solution obtained by reacting acetylsalicylic acid with magnesium carbonate in t...	07/18/1989
4783551	Potassium acetylsalicylate addition compound and process of preparing The invention is drawn to a compound of the formula ##STR1## which can be prepared by the reaction of acetylsalicylic acid with potassium carbonate or potassium bicarbonate in the presence of minor amounts of water. The compound is a substantially st...	11/08/1988
4764637	Hydrated magnesium acetylsalicylate/urea complex preparation The hydrated complex of magnesium acetylsalicylate and urea of formula ##STR1## possesses exceptional analgesic and antipyretic properties. It may be crystallized from a solution obtained by reacting acetylsalicylic acid with magnesium carbonate in t...	08/16/1988
4748174	Water soluble salts of an NSAID with meglumine/glucamine The water soluble acid addition salts of an NSAID, such as acetylsalicylic acid, fenbufen, diflunisal, piroxicam, naproxen, or the like, with either glucamine or meglumine (N-methylglucamine) are useful anti-inflammatory and analgesic drugs, well adopted ...	05/31/1988
4724266	Pharmaceutical composition with antithrombotic activity The present invention provides combination of materials for strengthening the antithrombotic action of acetylsalicylic acid. It covers a composition which contains diltiazem or a pharmaceutically acceptable acid-addition salt thereof in combination with a...	02/09/1988
4692546	Process for producing acyloxy aromatic carboxylic acids Acyloxy aromatic carboxylic acids, e.g., 4-acetoxybenzoic acid, are prepared by oxidizing with oxygen an acyloxy aromatic ketone, e.g., 4-acetoxyacetophenone in the presence of manganese cations and a lower-carboxylic acid anhydride as catalyst and a co-r...	09/08/1987
4324801	Phenylguanidine acetylsalicylate compounds, process for production thereof, and pharmaceutical composition thereof A compound of the formula ##STR1## wherein R1 is a member selected from the group consisting of a hydrogen atom, lower alkyl groups and lower alkoxy groups, R2 is a member selected from the group consisting of a hydrogen atom, h...	04/13/1982
4316046	Process for the preparation of aryl carboxylates A process for the preparation of aryl carboxylates is provided in which an arylmetallo carboxylate is contacted with an aryliodoso carboxylate in liquid medium to form the desired aryl carboxylate. Promoters can be employed to increase the rate of reactio...	02/16/1982
4316045	Catalytic process for the production of aryl carboxylates A process for the catalytic preparation of aryl carboxylates is provided in which an arylmetallo carboxylate is contacted in liquid medium with an organic peracid in the presence of a catalytic amount of an aryl iodide, to form the desired aryl carboxylat...	02/16/1982
4218445	N,N'Dibenzylethylenediamine-diacetylsalicylate, a novel chemotherapeutic agent for pain relief by external application N, N'-dibenzylethylenediamine-diacetylsalicylate for effecting an analgesic, antipyretic, spasmolytic or anti-inflammatory response in a mammalian host....	08/19/1980
4096252	4-Trifluoromethylbenzoic acid derivatives as thromboembolic agents 2-OR-4-trifluoromethylbenzoic acid wherein R is H or acyl. The compounds are useful in the treatment of pathological cardiovascular conditions, particularly in the prophylaxis of the thromboembolic diseases. The compounds are made by reacting m-trifluoromethyl...	06/20/1978
3985792	Stable sodium acetylsalicylate and method for its manufacture A novel crystalline form of sodium acetylsalicylate (sodium aspirin) is obtained by first precipitating sodium aspirin dihydrate in crystalline form and thereafter dehydrating it to form anhydrous sodium aspirin. The process is carried out under controlle...	10/12/1976
3957853	Metformine salt of acetylsalicylic acid The invention provides metformine monoacetylsalicylate as a novel salt hag valuable pharmacological properties, particularly for the treatment of glycemia....	05/18/1976

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Class 560/143 - Salicylic acid or functional derivative