Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7417059 | Substituted aromatic-ring compounds, process for producing the same and use The present invention is directed to a class of cyclohexene derivatives bearing sulfamoyl and ester groups which have an inhibitory activity on nitric oxide (NO) production and cytokine production, and are useful as an agent for the prophylaxis and/or treatment of d... | 08/26/2008 |
| 7358319 | Copolymerizable photoinitiators for UV-crosslinkable adhesives The invention relates to radically copolymerizable acetophenone or benzophenone derivatives, obtained by reaction of a) (meth)acrylic compounds exhibiting at least one isocyanate-reactive group [compounds a)] with b) compounds exhibiting at... | 04/15/2008 |
| 7351825 | Cyclopropane compounds and pharmaceutical use thereof The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula (1): | 04/01/2008 |
| 7312177 | Thermosensitive recording materials A thermosensitive recording material comprising a substrate sheet and a thermosensitive colored image-forming layer formed on at least one surface of the substrate sheet and comprising at least one colorless or light-colored dye precursor and a color-developing agen... | 12/25/2007 |
| 7262317 | Freeze-dried preparation of n[o-(p-pivaloyloxybenzenasulfonylamino) benzoyl] glycine monosodium salt tetrahydrate and process for producing same A method for the preparation of a freeze-dried product of N-[o-(p-pivaloyloxybenzenesulfonylamino)benzoyl]glycine monosodium salt tetra-hydrate dissolved in a mixed solvent of water and ethanol, and the freeze-dried product obtained by the method. According t... | 08/28/2007 |
| 7244845 | Process for preparing cyclic N-substituted alpha-imino carboxylic acids The present invention relates to the novel methods of making matrix metalloproteinase inhibitors of Formula (I): ... | 07/17/2007 |
| 7230031 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof The present invention provides a compound represented by general formula (I): or pharmaceutically acceptable salts thereof, wherein W is O, S(O)m, CH2 and the like; R1 is halogen,... | 06/12/2007 |
| 7199265 | Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds and to methods for using such compounds such as in the regulation of m... | 04/03/2007 |
| 7189848 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation The present invention relates to a compound of the formula (I) The compound according to the invention is suitable for the preparation of herbicidal active substances such as sulfonylureas. ... | 03/13/2007 |
| 7179581 | Resist composition and patterning process Resist compositions comprising nitrogen heterocyclic compounds having a pyrrole or nitrogen-bearing 5-membered ring structure and a polar functional group have an excellent resolution and an excellent focus margin and are useful in microfabrication using electron be... | 02/20/2007 |
| 7153869 | Substituted amino acids as erythropoietin mimetics This invention relates to a series of substitituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molec... | 12/26/2006 |
| 7094919 | Preparation of substituted aromatic carboxylic acid esters Methods for preparing substituted aromatic carboxylic acid esters are described. In particular, the invention relates a method for preparing a nitro-substituted aromatic carboxylic acid ester: Additionally the inventio... | 08/22/2006 |
| 7084178 | Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides derivatives A series of N-cycloalkylcarboxamide derivatives of N-benzyl benzenesulfonamides of Formula I are described. The compounds inhibit β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's... | 08/01/2006 |
| 7071358 | Arylsulfonamidobenzylic compounds Arylsulfonamidobenzyl alcohols, amines and sulfonamides are provided which are useful in treating lipid disorders, metabolic diseases and cell-proliferative diseases. ... | 07/04/2006 |
| 7038073 | Synthesis of 2-alkyl amino acids A method of preparing a 2-alkyl amino acid involves the aziridination of an alkylacrylate and the opening of the aziridine ring by addition of a side chain. This method can result in the preparation of enantiomeric excess of a 2-alkyl amino acid. The invention also ... | 05/02/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 7034045 | Monofluoroalkyl derivatives The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders. ... | 04/25/2006 |
| 7002036 | Synthesis of 2-alkyl amino acids Non-natural amino acids such as 2-alkylated amino acids allow for the synthesis of a wider variety of peptidal and non-peptidal pharmaceutically active agents. A method of preparing a 2-alkyl amino acid involves a Michael-type addition of a nucleophile to a dialkyl ... | 02/21/2006 |
| 6998423 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders includ... | 02/14/2006 |
| 6982344 | Process for preparation of optically active sulfonamides and intermediates for their synthesis A method including resolution of a diastereomeric mixture represented by the formula wherein R1 and R2 are the same or different and each is an optionally substituted hydrocarbon group or an optio... | 01/03/2006 |
| 6936719 | Biaryl compounds as serine protease inhibitors Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat and/or prevent clotting disorders, and as anticoagulating agents. ... | 08/30/2005 |
| 6927224 | Selective estrogen receptor modulators The present invention provides, inter alia, triphenylethylene derivatives, such as, 3-{4-[6-(3-Methoxy-phenyl)-8,9-dihydro-7H-benzocyclohepten-5-yl]-phenyl}-acrylic acid, as selective estrogen receptor modulators. Also provided are methods for the treatment and/or p... | 08/09/2005 |
| 6916593 | Resist composition Although use of a nitrogen-containing compound as a basic compound component of a resist composition makes it possible to ease the T-top problem at an acid dissociation constant pKa falling within a range of 2 to 6, it is accompanied with the problem that the reacti... | 07/12/2005 |
| 6884821 | Carboxylic acid derivatives and drugs containing the same Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R1 is hydro... | 04/26/2005 |
| 6884903 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation The present invention relates to a compound of the formula (I) The compound according to the invention is suitable for the preparation of herbicidal active substances such as sulfonylureas. ... | 04/26/2005 |
| 6818765 | Benzene-sulphonamide derivatives and their uses Benzene-sulphonamide derivatives complying with the general formula (I): in which the different symbols have different meanings, their optical isomers and the salts pharmacologically acceptable of these derivatives, as... | 11/16/2004 |
| 6815556 | Compounds having fungicidal activity and processes to make and use same A compound according to formula one that is useful as a fungicide is provided. Additionally, processes to make and use same are provided. ... | 11/09/2004 |
| 6699994 | Biaryl compounds as serine protease inhibitors Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat and/or prevent clotting disorders, and as anticoagulating a... | 03/02/2004 |
| 6686494 | Synthesis of S-alkyl and S-aryl thiocarbamates, one-pot two-step general synthesis A method for preparing S-alkyl and S-aryl thiocarbamates comprising reacting a precursor thiol reagent with trichloroacetyl chloride to produce an S-alkyl and S-aryl trichloroacetyl thioester intermediate, which is reacted with an amine to yield the corre... | 02/03/2004 |
| 6677472 | Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same A thermosensitive recording material having high whiteness and resistance to color formation under high temperature, high humidity conditions has a thermosensitive colored image-forming layer formed on a substrate sheet and includes a dye precursor, a bin... | 01/13/2004 |
| 6649656 | Anthranilic acid derivatives The present invention relates to an anthranilic acid derivative expressed by the following formula (1) or the following formula (2), or its pharmacologically permissible salt or solvate. ##STR1##... | 11/18/2003 |
| 6613937 | S-nitroso- and S-nitro-N-acyl-L-cysteine ester derivatives as pharmalogically active agents and pharmaceutical compositions containing said compounds SNACE derivatives as pharmacological active agents and pharmacological compositions containing these compounds, in particular for transdermal, oral, rectal and inhalational application, are described.... | 09/02/2003 |
| 6590119 | Methods for the synthesis of dioxoalkanoic acid compounds The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.... | 07/08/2003 |
| 6573387 | Synthesis of ,ଲ-substituted amino amides, esters, and acids ,ଲ-Unsaturated amides and esters are converted to ,ଲ-substituted amino amides, esters, and acids. An ,ଲunsaturated amide or ester is first converted to an ,ଲ-hydroxysulfonamide or hydroxycarbamate amide ... | 06/03/2003 |
| 6566547 | Fungicides This invention relates to derivatives of acrylic acid useful as fungicides, to processes for preparing them, to fungicidal compositions containing them, and to methods of combating fungi, especially fungal infections in plants, using them.... | 05/20/2003 |
| 6552061 | Amino acid derivatives and anti-inflammatory agents Provided are an anti-inflammatory agent containing, as an active ingredient, at least one selected from amino acid derivatives represented by formula (I) ##STR1## wherein Ar represents an optionally substituted 2-hydroxyaryl group, n is 0 or 1, R | 04/22/2003 |
| 6541422 | Method for improving the selectivity of 1,3-cyclohexanedione herbicide A method of selectively controlling undesirable vegetation in crops by using a postemergent application of an herbicidally effective amount of a metal chelate of a 2-(substituted benzoyl)-1,3-cyclohexanedione compound to the locus of such undesirable vege... | 04/01/2003 |
| 6506764 | Hydroxamic and carboxylic acid derivatives Compounds of the formula B--X--(CH2)m --CR1 R2 --(CH2)n --CO--Y (I) have therapeutic utility as inhibitors of metalloproteinases etc.... | 01/14/2003 |
| 6506944 | Preparation of substituted olefins C6 compounds of the formula (I) E--CH2 --CH.dbd.CH--CH2 --E1 (I) are prepared by self metathesis or cross metathesis of compounds of the formulae (II) and/or (III) R--CH.dbd.CH--CH2 --E (II) R1 --C... | 01/14/2003 |
| 6503949 | Glucagon antagonists/inverse agonists Disclosed is a novel class of compounds of formula (I) ##STR1## wherein V, A, Y, Z, R1, E, X and D are as defined in the specification. These compounds act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to thei... | 01/07/2003 |
