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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 7462734 | Process for production of optically active α-fluoro-carboxylic ester derivatives The present invention relates to a process for producing an optically active α-fluorocarboxylate derivative represented by the formula [2], by reacting an optically active α-hydroxycarboxylate derivative with trifluoromet... | 12/09/2008 |
| 6989462 | Synthesis of 2-chloromethyl-6-methylbenzoic ester A process is described for preparing compounds of formula (I) where R is H, optionally halogen-substituted alkyl, cycloalkyl, aryl, alkyl-aryl or heteroaryl, and, in alkyl and cycloalkyl, one or more CH2 grou... | 01/24/2006 |
| 6972340 | Selective protein tyrosine phosphatatase inhibitors Compounds of formula (I) or therapeutically acceptable salts thereof, are selective protein tyrosine kinase-B (PTP1B) inhibitors. Preparation of the compounds, compositions containing the compounds, and treatment of di... | 12/06/2005 |
| 6946566 | Process for preparation of optically active halogeno hydroxypropyl compound and glycidyl compound A process for preparing regioselectively an optically active 1-halogeno-2-hydroxypropyl compound of the following formula; wherein X is halogen atom and Nu is a heteroatom having a substituent,... | 09/20/2005 |
| 6753444 | Method for producing 2,3,5,6-tetrahalogen-xylyidene compounds The invention relates to a process for preparing 2,3,5,6-tetrahaloxylylidene compounds of formula (I) where each Hal is independently fluorine or chlorine, and X is fluorine, chlorine, bromine, —O—R, or —O—C(═O... | 06/22/2004 |
| 6392089 | Photoreleasable protecting groups on alcohols, phosphates and diacids and the use thereof Alcohol, phosphate, and diacid derivatives that may be deprotected by irradiation are disclosed. The protecting group is an arylacyl or heteroarylacyl group.... | 05/21/2002 |
| 6111130 | Process for the preparation of trifluoromethyl containing derivatives The present invention relates to a process for the preparation of trifluoromethylated derivatives of the formula CF3 CCl.dbd.CHCH2 OC(.dbd.O)R, wherein R is unsubstituted or substituted C1 to C6 straight chain o... | 08/29/2000 |
| 5869506 | Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof The present invention provides a fluoropropene compound represented by Formula I: ##STR1## wherein R1 represents a C1 -C10 alkyl group or other groups, Z represents an oxygen atom or other groups, R2, R | 02/09/1999 |
| 5756816 | Process for the production of phenol derivatives A process for the production of a phenol derivative of the formula (2), which comprises subjecting a diester compound of the formula (1) in which a hydroxyl group is protected by an acyl group, to a reaction for removal of protection, wherein the reaction... | 05/26/1998 |
| 5665877 | Synthesis of bisindolylmaleimides The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because i... | 09/09/1997 |
| 5614647 | Intermediates for the synthesis of bisindolylmaleimides The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because i... | 03/25/1997 |
| 5541347 | Synthesis of bisindolylmaleimides The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because i... | 07/30/1996 |
| 5488133 | Iodinated aroyloxy ketones Compounds having the structure ##STR1## wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 20; R1, R2, R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, ary... | 01/30/1996 |
| 5455371 | Method of producing difluoromethyl ethers and esters and ethers and esters produced thereby A process for producing difluoromethyl ethers and esters by reacting an ether or an acid with a cadmium, zinc or bismuth compound containing the CF3 group and selected from the group consisting of Cd(CF3)2, Zn(CF3 | 10/03/1995 |
| 5453468 | Prepolymers containing a perfluoropolyethereal chain and carboxylic end groups, suitable as cross-linking agents for epoxy prepolymers The invention relates to two classes of prepolymers containing a perfluoropolyethereal chain and carboxylic end groups, suitable as cross-linking agents for epoxy prepolymers. The first class contains anhydride-derived end groups; the second lactone-deriv... | 09/26/1995 |
| 5374376 | Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element Disclosed are herein optically active aromatic compounds represented by the formula (I): ##STR1## wherein X represents --COO-- or --OCO--; Y represents --COO--, --OCO-- or --O--; R2 represents an alkyl or alkoxyalkyl group having 1 to 20 ... | 12/20/1994 |
| 5344638 | Compositions of iodobenzoic acid derivatives for visualization of the gastrointestinal tract Disclosed are contrast agents of the formula ##STR1## contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract wherein wherein Z=H, halo, C1 -C20 alkyl, cycloalkyl, lower alkox... | 09/06/1994 |
| 5292928 | Process for the reaction of a low-molecular hydroxyl compound with a carboxylic acid halide In a process for reacting a low molecular weight hydroxy compound with a carboxylic acid halide, a small amount of the acid halide is introduced into the reaction vessel and the remainder of the acid halide and the hydroxy compound are added gradually in ... | 03/08/1994 |
| 5275757 | Liquid crystal compounds and liquid crystal display devices Novel anti-ferroelectric liquid crystal compounds represented by the following general formula (I) and a liquid crystal display element wherein such a compound is used. ##STR1## Ph represents a phenylene group, R represents a straight-chain alkyl gro... | 01/04/1994 |
| 5254732 | N-fluorosulfonimides and their application as fluorinating agents The invention describes N-fluorosulfonimides which are useful as fluorinating agents. The N-fluorosulfonimides are stable, easily synthesized, and allow the introduction of fluorine into organic compounds under mild conditions.... | 10/19/1993 |
| 5238603 | Optically active liquid crystalline compound and a composition containing same A liquid crystal compound having specific features suitable to use for a display mode utilizing ferroelectric liquid crystals, particularly a large spontaneous polarization value and a liquid crystal composition using the compound are provided, which comp... | 08/24/1993 |
| 5207946 | Liquid crystal compounds A liquid crystal compound represented by formula (I): ##STR1## wherein R1 represents an alkyl group having from 3 to 18 carbon atoms; R2 represents an alkyl group having from 3 to 18 carbon atoms; X represents ##STR2## ... | 05/04/1993 |
| 5175348 | Process for the preparation of halogenated carboxylic acid esters The invention relates to a novel process for the preparation of halogenated carboxylic acid esters of formula I ##STR1## wherein R1 is alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl or aryl, R2 hydrogen is alkyl or cycloalkyl, and... | 12/29/1992 |
| 5171879 | Process for the preparation of chlorinated carboxylic acid esters The invention relates to a novel process for the preparation of chlorinated carboxylic acid esters of formula I ##STR1## wherein R1 is alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl or aryl and R2 hydrogen is alkyl or cycloalkyl, ... | 12/15/1992 |
| 5149843 | Conjugated diene compounds Conjugated diene compounds of the general formula: ##STR1## which are industrially advantageous intermediates for preparing sarcophytol A useful as an anticarcinogenic promotor or antitumor agent are provided.... | 09/22/1992 |
| 5136061 | Optically active pentane derivatives and intermediates thereof, and process for manufacturing same An optically active pentane compound of the general formula (I): ##STR1## wherein R1 represents a lower alkyl group having 1 to 4 carbon atoms, R2 represents a lower alkoxycarbonyl group having an alkoxy moiety of 1 to 4 carbon ... | 08/04/1992 |
| 5124070 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element Disclosed are herein optically active ester derivatives represented by the formula (I): ##STR1## (wherein R1 represents an alkyl group having 3 to 20 carbon atoms; R2 represents an optically active alkyl or alkoxyalkyl group hav... | 06/23/1992 |
| 5098602 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements This invention provides a novel halogen-containing ester compound represented by the following general formula (I): ##STR1## (wherein R is an alkyl group, A is selected from a single bond, --O--, --COO-- and --CO--, both of X and Y are halogen atoms ... | 03/24/1992 |
| 5011943 | FK-506 C10 -C24 process intermediates A process is described for the improved synthesis of the optically pure C10 -C24 fragment of the macrolide structure of the immunosuppressant FK-506. This compound is also useful as an intermediate for preparing FK-506 derivatives.... | 04/30/1991 |
| 4999454 | Process for the preparation of trichloromethyl carbinols The invention is directed to a new process for the preparation of carbinols of the general formula I ##STR1## by reaction chloral and olefins of the general formula ##STR2## and by optional acylation of the product comprising dissolving a cataly... | 03/12/1991 |
| 4985588 | Nucleus-fluorinated aromatic carboxylates and processes for their production A process for producing nucleus-fluorinated aromatic carboxylates, which comprise nucleus-fluorinating aromatic carboxylates of the following formula (1) with a fluorinating agent to obtain nucleus-fluorinated aromatic carboxylates of the following formul... | 01/15/1991 |
| 4973735 | Substituted trifluoroethyl esters of phenylacetic acid, processes for their preparation and their use as pesticides There are described new trifluoroethyl esters of phenylacetic acid of general formula I ##STR1## in which R1 and R2 have the meanings given in the description and processes for their preparation. The compounds show insecticidal ... | 11/27/1990 |
| 4959187 | Glycolate ester peracid precursors The invention provides novel bleaching compositions comprising peracid precursors with the general structure ##STR1## with R, R', R" and L as defined in the specification. Novel peracids and precursors are also herein disclosed. These peracid precurs... | 09/25/1990 |
| 4939290 | Benzoic acid derivatives Quinolonecarboxylic acid intermediaes useful in the preparation of antibacterial 6-fluouro-7-substituted-quinolonecarboxylic acids are prepared from 2-(iodo, bromo or chloro)-3-fluoro-4-(fluoro or chloro)-phenyl carboxylic acid or ester.... | 07/03/1990 |
| 4933510 | Propanol derivatives Propanol derivatives of formula (I) wherein X is a leaving group; R1 is H or a protecting group; and R2 is H, and R3 is a group--CH2 Y wherein Y is a leaving group; or R2 and R3 together fo... | 06/12/1990 |
| 4917817 | Optical active compound, process for producing same and liquid crystal composition containing same An optically active functional compound represented by the following formula (1) is disclosed: ##STR1## wherein R denotes an alkyl group having 1-14 carbon atoms; -X- denotes ##STR2## denotes a single bond, ##STR3## n=0, 1 or 2; and C*... | 04/17/1990 |
| 4898970 | Process for producing fluorinated esters This invention relates to a process for producing a fluorinated ester containing a trifluoromethyl group by esterification in the presence of γ-butyrolactone as a solvent, and more particularly a process or producing a fluorinated ester containing a trif... | 02/06/1990 |
| 4894181 | Carbocyclic compounds Carbocyclic compounds of the formula I ##STR1## wherein Q is a benzene or cyclohexane ring or a naphthalene system, X is in each case --CH2 --(CH2)p -- where it is also possible for one or two non-adjacent CH2 | 01/16/1990 |
| 4886619 | Fluorine-containing chiral smectic liquid crystals Compounds are provided which comprise a fluorocarbon terminal portion and a chiral hydrocarbon terminal portion, said terminal portions being connected by a central core, said compounds having tilted smectic mesophases or having latent tilted smectic meso... | 12/12/1989 |
| 4873018 | Optically active compound, process for producing same and liquid crystal composition containing same An optically active 2-fluoro-1-alkanol compound represented by the formula (Ia): ##STR1## wherein R is an alkyl group having 1-16 carbon atoms, and C* is an asymmetric carbon atom; and an optically active compound derived from the fluoroalkanol ... | 10/10/1989 |
