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| Number | Title | Issue Date |
| 8173830 | Vinyl ester production from acetylene and carboxylic acid utilizing homogeneous catalyst A process for the selective production of vinyl ester by the reaction of a carboxylic acid with acetylene with a homogeneous catalyst is disclosed and claimed. In a preferred embodiment of this invention, reaction of benzoic acid and acetylene in the presence of Gro... | 05/08/2012 |
| RE43006 | Aryl-acrylic acid esters The acrylic acid esters of Formula I are useful for the delivery of organoleptic compounds, especially for flavors, fragrances, masking agents and antimicrobial compounds. They can also deliver fluorescent whitening agents. ... | 12/06/2011 |
| 7473797 | Methods of 1,3-enyne preparation using copper (I) catalysts A copper(I) bi-dentate ligand complex-catalyzed procedure for synthesis of 1,3-enynes. The methods and/or systems of this invention afford a variety of enynes, tolerate a variety of sensitive functional groups, and can be employed without resort to expensive palladi... | 01/06/2009 |
| 7381832 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives Polyhalogenated cinnamic acids and cinnamic acid derivatives are prepared by reacting diazonium salts accessible from polyhalogenated anilines with acrylic acid or acrylic acid derivatives in the presence of a homogeneous, palladium-containing catalyst at about −5... | 06/03/2008 |
| 7235583 | Fatty acid-anticancer conjugates and uses thereof The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided. ... | 06/26/2007 |
| 7157458 | Bifunctional energy-reversible acyl-compositions Energy-reversible acyl conjugates, intermediates, and related compositions are disclosed. In preferred aspects, examples of such compositions include: ... | 01/02/2007 |
| 7129247 | Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents The present invention relates to novel heterocyclyl-containing diaryl sulfide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing... | 10/31/2006 |
| 7115728 | Human peroxisome proliferator activated receptor γ The present invention relates to a novel human peroxisome proliferator activated receptor, hPPARγ. hPPARγ differs from the mouse peroxisome proliferator activated receptor γ in the nucleotide sequence and the amino acid sequence. The invention provides isolated, ... | 10/03/2006 |
| 7098025 | Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor This invention relates to the isolation and cloning of the promoter and other control regions of human PPARγ gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the level o... | 08/29/2006 |
| 7084281 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins A novel synthesis reaction for highly stereospecific tri- and tetra-substituted olefins is described. A single stereoisomer of stable α-halo-α,β-ester is produced in high yield by the reaction of aldehyde or ketone with a trihalogenated compound such as trichloro... | 08/01/2006 |
| 7081281 | Polymerizable liquid crystal compound, liquid crystal composition and optical anisotropic material The present invention provides a polymerizable liquid crystal compound having an excellent durability against blue laser light and having a small refractive index and small light absorption, a liquid crystal composition containing the compound, and an optical anisot... | 07/25/2006 |
| 7071151 | Compositions comprising photo-labile perfume delivery The present invention relates to photo-labile pro-fragrances, as well as a fragrance raw material delivery system comprising: i) from about 0.001% to about 100% by weight, of a photo-labile pro-fragrance compound having the formula... | 07/04/2006 |
| 7019104 | Diamine novel acid dianhydride and novel polyimide composition formed therefrom An object of present invention is to provide a diamine and an acid dianhydride having photoreactivity and thermoreactivity and a polyimide composition containing the diamine and the acid dianhydride as monomer components, and specifically to synthesize a diamine and... | 03/28/2006 |
| 6977057 | Embossing process A method for manufacturing an embossed surface including a polymer composition having reactive moieties and a first glass transition temperature of Tg1. The method includes embossing the surface at temperature Temb; and raising the first glass ... | 12/20/2005 |
| 6956129 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives Polyhalogenated cinnamic acids and cinnamic acid derivatives are prepared by reacting diazonium salts accessible from polyhalogenated anilines with acrylic acid or acrylic acid derivatives in the presence of a homogeneous, palladium-containing catalyst at about −5... | 10/18/2005 |
| 6936636 | 5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity Compounds of the formula: where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects... | 08/30/2005 |
| 6927302 | Process for the arylation of olefins The present invention encompasses a process for preparing arylolefins by reacting one or more arylamines with one or more organic nitrites, in the presence of one or more olefins which bear at least one hydrogen atom on the double bond and in the presence of acid an... | 08/09/2005 |
| 6730798 | Process for the preparation of substituted octanoyl amides Compounds of formula (II) are simultaneously halogenated in the 5 position and hydroxylated in the 4 position under lactonization, the halolactone is converted into a hydroxylactone and then the hydroxy group into a leaving group, the leaving group is replaced with ... | 05/04/2004 |
| 6720445 | Acetyloxymethyl esters and methods for using the same Novel acetyloxymethyl esters are disclosed. Methods of treating an illness, including cancer, hemological disorders and inherited metabolic disorders, and treating or ameliorating other conditions using these compounds are also disclosed. The compounds are effective... | 04/13/2004 |
| 6696606 | Solid phase synthesis of arylretinamides A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reactin... | 02/24/2004 |
| 6689899 | Diamine and acid anhydride The present invention provides a novel diamine and a novel acid anhydride which are applicable for a polyimide and includes a cinnamoyl group or a derived cinnamoyl group. The novel diamines and acid anhydrides have photo-reactivity and heat-reactivity in... | 02/10/2004 |
| 6667341 | Delta dicarbonyl compounds and methods for using the same Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having an oxygen, s... | 12/23/2003 |
| 6599938 | Compounds having MIF antagonist activity There is disclosed a genus of optionally substituted Schiff base condensation products (and the carba analogs thereof) comprising an amino acid component and a benzaldehyde component, that have MIF (macrophage migration inhibitory factor) antagonist activ... | 07/29/2003 |
| 6590119 | Methods for the synthesis of dioxoalkanoic acid compounds The invention relates to improved methods of producing aryl dioxoalkanoic acid compounds and derivatives useful as intermediates for diarylpyrrole therapeutic agents by the alcoholysis of benzoylcyclohexanone ketal compounds.... | 07/08/2003 |
| 6566560 | Resorcinolic compounds The invention provides a resorcinol derivative and a method of using the resorcinol derivative to attenuate the growth of a neoplasm.... | 05/20/2003 |
| 6562995 | Delta dicarbonyl compounds and methods for using the same Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having an oxygen, s... | 05/13/2003 |
| 6538154 | Process for the preparation of cinnamic esters The present invention relates to a process for the synthesis of cinnamic esters and/or cinnamic acids by condensation of aldehydes with carboxylic anhydrides, using iron(II) salts as catalyst.... | 03/25/2003 |
| 6531625 | Cinnamic esters In a novel process for the synthesis of cinnamic esters or substituted cinnamic esters, carboxylic esters are reacted, by condensation, with benzaldehyde or substituted benzaldehydes, respectively, in the presence of a solid with basic properties.... | 03/11/2003 |
| 6509493 | Method for producing atropic acid ethyl ester A process for preparing ethyl atropate by reacting ethyl phenylacetate with paraformaldehyde in the presence of a base is described and entails employing as ethyl phenylacetate a product which contains not more than 0.03% of the corresponding methyl pheny... | 01/21/2003 |
| 6495719 | Histone deacetylase inhibitors Compounds having a zinc-binding moiety, such as, for example, a hydroxamic acid group, can inhibit histone deacetylase. Histone deacetylase inhibition can repress gene expression, including expression of genes related to tumor suppression. Inhibition of h... | 12/17/2002 |
| 6436991 | Composition and method containing products extracted from Commiphora sp. for prevention and treatment of abnormal cell growth and proliferation in inflammation, neoplasia and cardiovascular disease Ferulate compounds derived from extracts from the plant Commiphora wightii are used in compositions and methods for prevention and treatment of abnormal cell growth and proliferation in inflammation, neoplasia and cardiovascular disease.... | 08/20/2002 |
| 6392111 | Method for producing olefins Olefins containing aromatic substituents are synthesized without the addition of phosphonium salts or phosphanes with the aid of a PdII compound as a catalyst in the presence of nitrogen-containing additives such as N,N-dimethylglycine and a ba... | 05/21/2002 |
| 6362357 | Use a catalyst system comprising nickel palladium or platinum and imidazoline-2-ylidene or imidazolidine-2-ylidene in stille coupling reactions This invention provides a process for conducting Stille coupling reactions. The processes of the present invention make use of N-heterocyclic carbenes as ancillary ligands in Stille couplings of aryl halides. A Stille coupling can be carried out by mixing... | 03/26/2002 |
| 6331655 | Process for the preparation of aromatic carbonyl compounds from styrenes The present invention relates to a novel process for the preparation of aromatic carbonyl compounds by oxidative cleavage of styrenes using lipases and hydrogen peroxide or hydrogen peroxide donors in the presence of carboxylic acids or carboxylic esters.... | 12/18/2001 |
| 6313340 | Process for the preparation of methyl p-vinylbenzoate and p-vinyl benzoic acid, and their use in latex compositions The present invention describes a process for the direct preparation of methyl p-vinylbenzoate from methyl p-formylbenzoate using ketene in the presence of potassium acetate. The chief products obtained from the process are about a five to two ratio of me... | 11/06/2001 |
| 6207857 | Precursor compounds The compounds of the formula I ##STR1## are precursors for organoleptic and antimicrobial compounds. The latter are generated in the presence of skin bacteria, enzymes or acidic or alkaline conditions. One precursor molecule can provide one or more differ... | 03/27/2001 |
| 6162943 | Method for producing -alkoxy--trifluoromethyl-aryl acetic esters and -aryl acetic acids Process for the preparation of -alkoxy--trifluoromethyl-arylacetic esters of the formula (I) ##STR1## wherein R is a component selected from the group consisting of C1 -C6 -alkyl, C2 -C6 ... | 12/19/2000 |
| 6133471 | Process for producing chromans A process for producing chromans, comprising reacting a phenol, a formaldehyde and an alcohol in the presence of a secondary amine and an acid, to generate an alkoxymethylphenol compound with the ortho position to the phenolic hydroxyl group substituted w... | 10/17/2000 |
| 6130349 | Catalytic compositions and methods for asymmetric allylic alkylation Complexes of a selected class of chiral ligands with molybdenum, tungsten or chromium, preferably molybdenum, are effective as catalysts in highly enantioselective and regioselective alkylation of allylic substrates. Such compositions provide a versatile ... | 10/10/2000 |
| 6124495 | Unsaturated oxyalkylene esters and uses thereof This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating cutaneous ulcers, treating gastrointestinal disorders, treating b... | 09/26/2000 |
