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| Number | Title | Issue Date |
| 7754912 | Polymerizable compounds A novel polymerizable compound of the present invention is represented by the following general formula (I). Due to the presence of a reactive phenolic hydroxyl group at the end of the molecule, it can be reacted easily with various functional compounds and is usefu... | 07/13/2010 |
| 7413782 | Polymerizing binaphthalene derivatives Provided are a polymerizing liquid-crystalline compound of formula (1). In formula (1), Q1 to Q4 each independently represent a formula (2), a hydrogen atom, a halogen atom, an alkyl group or the like;... | 08/19/2008 |
| 7345189 | Process for the preparation of adapalene A process for the preparation of a compound of formula (I), or a salt thereof wherein R is H, C1-C8 alkyl, aryl or aryl-C1-C8 alkyl; comprising the reaction between a compound of ... | 03/18/2008 |
| 7329368 | Temperature compensating chiral dopants The present invention relates to a chiral compound, and an article utilizing the same, represented by the following structures I-1, I-2, I-3, or 1-4: wherein the chiral compound demonstrates thermochromic tempera... | 02/12/2008 |
| 7247742 | Recycling polyethylene naphthalate containing materials in a process to produce diesters A process for preparing a dialkylester of a naphthalenedicarboxylic acid comprising directing a liquid phase reaction mixture comprising a low molecular weight alcohol, a naphthalenedicarboxylic acid, a dialkylester of a naphthalenedicarboxylic acid, and a polyethyl... | 07/24/2007 |
| 7166726 | Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity Disclosed herein are compounds of the formula wherein R1 is independently H or alkyl of 1 to 6 carbons; R2 is optional and is defined as lower alkyl of 1 to 6 carbons, F, Cl, Br... | 01/23/2007 |
| 7135590 | Gallic acid derivative and process of preparing the same This invention provides a plant growth regulatory activity of a new biologically active synthetic molecule methanone-(3′,4′,5′-trimethoxy) phenyl, 1-naphthyl, 2-O-4″-ethyl but-2″-enoate. More particularly, the invention relates to the potent plant growth p... | 11/14/2006 |
| 7129261 | Cytotoxic agents The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as ot... | 10/31/2006 |
| 7087600 | Peptidyl prodrugs and linkers and stabilizers useful therefor The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as ot... | 08/08/2006 |
| 7074826 | R-NSAID esters and their use The present invention concerns esters of R-enantiomers of a non-steroidal anti-inflammatory drug, which is substantially free from the S-enantiomer. The compounds of the invention may be used in treating a disease or illness in a mammal. To this end, a composition c... | 07/11/2006 |
| 7056954 | Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor In accordance with the present invention, there are provided methods to modulate processes mediated by retinoid receptors, employing high affinity, high specificity ligands for such receptors. In one aspect of the present invention, there are provided ligands which ... | 06/06/2006 |
| 6992108 | Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor A method for modulating lipid metabolism in a subject by administering 9-cis retinoic acid is presented. The 9-cis retinoic acid is more specific for the retinoid X receptor than is retinoic acid. ... | 01/31/2006 |
| 6984604 | Supported bis(phosphorus) ligands and their use in the catalysis Supported bis(phosphorus) ligands are disclosed for use in a variety of catalytic processes, including the isomerization, hydrogenation, hydroformylation, and hydrocyanation of unsaturated organic compounds. Catalysts are formed when the ligands are combined with a ... | 01/10/2006 |
| 6942980 | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities Methods of characterizing and identifying negative hormones of nuclear receptors. Also disclosed are methods of making modulators of retinoid nuclear receptor transactivation activity, assays for agonists, antagonists, and negative hormones of the RAR receptor, and ... | 09/13/2005 |
| 6905739 | Optically active materials A compound is of formula (I), in which: A1 to A4, E1 and E2 each independently represent hydrogen or an optionally-substituted hydrocarbon group; B1 and B2 each independently represent a single bond, ... | 06/14/2005 |
| 6897237 | MMP-12 inhibitors A compound of the formula (I): wherein R1 is hydroxy and the like; R2 is optionally substituted lower alkyl and the like; R3 is hydrogen atom and the like; R4 is optionally s... | 05/24/2005 |
| 6875895 | Bis (diphenylvinyl) arene compound Provided is a bis(diphenylvinyl)arene compound having a reactive functional group on phenyl group, represented by below formula (1), wherein, Ar is an arylene group and has one or more substituents; R1-R | 04/05/2005 |
| 6846890 | Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization A novel norbornene derivative represented by a general formula (1m) shown below is provided. By conducting a ring opening polymerization of this norbornene derivative, or by performing a subsequent hydrogenation following the ring opening polymerization, a ring open... | 01/25/2005 |
| 6835427 | Optically active compound and liquid crystal composition containing the compound An optically active compound containing 5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-bi-2-naphthol of the general formula (1) as an asymmetric source, wherein n is an integer of 1 to 10, Y is a hydrogen atom, an alkyl gr... | 12/28/2004 |
| 6770775 | Method of synthesizing optically enriched α-halo-esters, and product and composition therefrom A method of synthesizing highly optically enriched α-halo-esters comprises reacting acid halides with a cinchona alkaloid catalyst and a base to form intermediate ketenes. The ketenes are reacted with electrophilic halogenating reagents to produce α-halo-esters wi... | 08/03/2004 |
| 6747154 | Process for preparing scopine esters A process for preparing a compound of formula 1 from a compound of formula 2 the process comprising reacting in one step the compound of formula 2 with a compound of formula ... | 06/08/2004 |
| 6740256 | Chiral swallow-tailed liquid crystal and its fabrication method A chiral swallow-tailed liquid crystal is provided. The present chiral swallow-tailed liquid crystal is synthesized from a chiral material. The present chiral swallow-tailed liquid crystal is composed of the compound of (N,N′-diethyl (s)-2-{6-[4-(4′-alkoxyphenyl... | 05/25/2004 |
| 6730371 | Optically active compound and liquid crystal composition containing the compound An optically active compound of the following general formula (1) useful as a chiral dopant, and use thereof, wherein each of X and Y is independently a hydrogen atom or a fluorine atom, R is (C2H5)... | 05/04/2004 |
| 6727098 | Biaryl-type compounds, CD color fixing agent and method for determination of absolute configuration A novel achiral biaryl-type compound and a circular dichroism (CD) color fixing agent are provided. Furthermore, a method for determining an absolute configuration of a chiral compound is carried out by introducing the above achiral biaryl-type compound into the chi... | 04/27/2004 |
| 6720039 | Liquid crystalline compounds and process for producing the same A liquid crystalline compound having a novel structure and a process for producing the same are provided. The liquid crystalline compound is represented by the following general formula (I): wherein R1 and R | 04/13/2004 |
| 6699532 | Optically active compound and liquid crystal composition containing the compound An optically active compound of the general formula (1) useful as a chiral dopant, and use thereof for a liquid crystal composition, ##STR1## the above optically active compound having a remarkably large helical twisting power (HTP) of as large as 50 or m... | 03/02/2004 |
| 6627652 | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors Process of treatment of mammals, including humans to treat diseases or conditions of the type which are normally treated with retinoid-like compounds is disclosed, with pharmaceutical compositions containing an active compound which is a selective agonist... | 09/30/2003 |
| 6617469 | Process for preparing malonic diesters in a reactor with internal heat exchangers A process for preparing malonic diesters by carbonylation of haloacetic esters and reaction with monohydric alcohols and a base in the presence of a transition metal catalyst, preferably a catalytic cobalt carbonyl complex, using a stirred reactor with on... | 09/09/2003 |
| 6610883 | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass... | 08/26/2003 |
| 6610877 | Aromatic carboxylic acid derivatives Compounds of the formula ##STR1## wherein R1 is a residue of the formula ##STR2## and R2 -R10 have the significance given in the specification can be used as pharmaceuticals, particularly for the repair of photodamaged ... | 08/26/2003 |
| 6586618 | CC-1065 analog synthesis Improved synthesis of seco(-)CBI (5-hydroxy-3-amino-1-[S]-(chloromethyl)-1,2-dihydro-3H-benz(e)indole): ##STR1## and improved syntheses therefrom of a wide variety of CC-1065 analogs that comprise a cyclopropabenzidole (CBI) alkylating moiety, and which a... | 07/01/2003 |
| 6538161 | Fluorescent substances The objective of this invention is to provide fluorescent compounds comprising a naphthalene skeleton, an electron donating group substituted at the 2- or 1-position of the naphthalene skeleton, and an electron attractive group substituted at the 6- or 4-... | 03/25/2003 |
| 6495710 | Synthesis and use of dimethyl 1,5-naphthalenedicarboxlyates and intermediates therefrom The synthesis of dimethyl-1,5-naphthalenedicarboxylate and polymers and articles formed therefrom is disclosed, as well as applications for dimethyl-1,5-naphthalenedicarboxylate, its corresponding acid 1,5-NDA, and various synthesis intermediates.... | 12/17/2002 |
| 6492542 | Method for producing carboxylic acid tertiary alkyl ester A carboxylic acid tertiary alkyl ester (Chemical formula 1) of high purity is obtained at a high yield ratio, by continually adding an esterification agent possessing a monovalent acid group, which agent is ester-interchangeable with a tertiary alcohol, t... | 12/10/2002 |
| 6479693 | Process for the preparation of a saturated carboxylic acid The present invention relates to a process for the preparation of a carboxylic acid ester of the general formula II, ##STR1## wherein R is alkyl or aryl, R1 is aryl, substituted aryl, naphthyl or substituted naphthyl or alkyl, R2, R | 11/12/2002 |
| 6409812 | AZO compounds and process for producing the same A diamide type azo compound represented by the general formula (I): ##STR1## which is derived from 2-hydroxy-3,6-dicarboxylic acid and at least one of the amide moieties in the compound is an aliphatic amide moiety, various use of the same and process for... | 06/25/2002 |
| 6410592 | Aminomethylcarboxylic acid derivatives The present invention relates to aminomethylcarboxylic acid derivatives general formula (I), wherein Z is (CH2)n, O, S, SO, SO2 or N--R5 ; n is 0, 1 or 2; X represents 1-3 substituents independently selected fro... | 06/25/2002 |
| 6333435 | Process of synthesizing binaphthyl derivatives A process of synthesizing a compound of the formula 1: ##STR1## is disclosed, which comprises reacting a compound of the formula 2: ##STR2## with diphenylphosphine in the presence of an amine base and a nickel catalyst to produce a compound of formula 1.... | 12/25/2001 |
| 6323174 | Diene compound and process for producing the same The invention provides a chain diene compound with desirable regioselectivity, in the presence of a specific ruthenium compound. This chain diene compound is a promising raw material for terpene. It has a structure represented by the general formula (I): ... | 11/27/2001 |
| 6320068 | Preparation of arylphosphines The present invention pertains to a process for the preparation of an arylphosphine of the formula R1 OC--Ar--PR2 R3 wherein Ar is aryl or heteroaryl; R1 is an alkoxy or amine group; and R2 and R... | 11/20/2001 |
