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| Number | Title | Issue Date |
| 8097748 | Amorphous compound and production method thereof An amorphous compound of the formula (1): wherein the temperature showing an endothermic peak by differential scanning calorimetry (DSC) is 40 to 80° C. and the solution rate into n-hexane at 25° C. in the following test sy... | 01/17/2012 |
| 8097747 | Process for the alkylation of phosphorus-containing compounds A process for alkylating a phosphorus-containing compound to provide an alkylated phosphorus-containing compound is provided which comprises alkylating 5 phosphorus-containing compound possessing at least one phosphorus-hydrogen alkylatable site with reactant which ... | 01/17/2012 |
| 7408075 | Synthesis of phosphocholine ester derivatives and conjugates thereof Aspects of the present invention include methods of synthesizing phosphocholine analogues and the phosphocholine conjugates formed therefrom and their use in preventing infections caused by microorganisms. ... | 08/05/2008 |
| 7365113 | Phosphate ester flame retardants from resorcinol-ketone reaction products Flavan-based and spirodichroman compound-based phosphate esters prepared by reacting flavans and spirodichroman compounds with phosphorus oxychloride, monophenyl dichlorophosphate, or diphenyl chlorophosphate compounds are described. The flavans and spirodichroman c... | 04/29/2008 |
| 7288577 | Polyurethane foam containing flame retardant blend of non-oligomeric and oligomeric flame retardants A polyurethane foam can be flame retarded by the incorporation therein of a flame retardant blend that comprises: (a) a non-oligomeric non-halogenated organophosphorus flame retardant (e.g., a phosphate ester) that is adapted for use in a polyurethane foam formulati... | 10/30/2007 |
| 7279515 | Resorcinol carbonate-based phosphate ester compounds as flame retardants Resorcinol carbonate-based phosphate esters are prepared by reacting resorcinol carbonates with phosphorous oxychloride or a chlorophosphate. The resorcinol carbonates can be synthesized by the reaction of resorcinol with phosgene or diphenyl carbonate. The resorcin... | 10/09/2007 |
| 7256317 | Process for the preparation of surfactant alcohols and surfactant alcohol ethers, the prepared products and their use The invention describes a process for the preparation of novel surfactant alcohols and surfactant alcohol ethers by derivatization of olefins having from about 10 to 20 carbon atoms or of mixtures of such olefins to give alkanols, and optional subsequent alkoxylatio... | 08/14/2007 |
| 7229978 | Process for preparing water soluble phosphonooxymethyl derivatives of alcohol and phenol A process for making water-soluble phosphonooxymethyl ethers of hindered alcohol and phenol containing pharmaceuticals, such as camptothecin, propofol, etoposide, Vitamin E and Cyclosporin A. In particular, the process for preparing water-soluble phosphonooxymethyl ... | 06/12/2007 |
| 7214810 | Alkoxyamines derived from beta-phosphorylated nitroxides, and use thereof for preparing polymerized or non-polymerized mono- or polyalkoxyamines The invention relates to the use of alkoxyamines of formula (I): for the preparation of polymerized or non-polymerized mono- or polyalkoxyamines of formula (II): ... | 05/08/2007 |
| 7214811 | Derivative of phosphoric acid ester salt or phosphoric acid ester adduct or mixtures thereof, method for the production thereof and their use A derivative of phosphoric acid ester salt or adduct or a mixture thereof is obtained from a reaction product, polycondensed with at least one aldehyde, of at least one polyol phosphoric acid ester with at least one organic nitrogen base. The derivative is advantage... | 05/08/2007 |
| 7208132 | Purification of endohedral and other fullerenes by chemical methods The invention provides a method of separating a first and a second set of fullerenes in a fullerene mixture. In the method of the invention, a stable fullerene cation is formed of one of the first or the second set of fullerenes. The fullerene cation is then separat... | 04/24/2007 |
| 7198863 | Fullerene based proton conductive materials A fullerene-based proton conductor including a proton conductive functional group connected to the fullerene by an at least partially fluorinated spacer molecule. Also, a polymer including at least two of the proton conductors that are connected by a linking molecul... | 04/03/2007 |
| 7166737 | Method for manufacturing phosphonate esters The present invention relates to a new manufacturing method for phosphonate esters, which have utility as a carbon-carbon binding formation agent, as well as a synthesis intermediate for biologically active substances such as medical drugs and agri-chemicals. | 01/23/2007 |
| 7135583 | Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters A novel process for preparation of alkenylphosphine oxides or alkenylphosphinic acid esters provided by which the objective compounds can be easily, safely and efficiently synthesized and easily separated and purified with little formation of by-products. Specifical... | 11/14/2006 |
| 7084115 | Inositol pyrophosphates, and methods of use thereof The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention rela... | 08/01/2006 |
| 7049456 | Method for preparing O,O-dialkyl S-[2-(alkylthio)alkyl] phosphorodithioates The invention relates to a method of preparing O,O-dialkyl S-[2-(alkylthio)alkyl] phosphorodithioates by treating O,O-dialkyl dithiophosphoric acids with a base in the substantial absence of organic solvent to obtain O,O-dialkyl dithiophosphoric acid salts that are ... | 05/23/2006 |
| 7009067 | Hexa-citrated phytate and process of preparation thereof The present invention relates to a new chemical compound known as hexa-citrated phytate and a method of production thereof. The new chemical compound has six citrate molecules attached at the hydroxyl group of a citric acid to phosphates of a phytate molecule. This ... | 03/07/2006 |
| 7008713 | Fullerene-based proton conductive materials A fullerene-based proton conductor including a proton conductive functional group connected to the fullerene by an at least partially fluorinated spacer molecule. Also, a polymer including at least two of the proton conductors that are connected by a linking molecul... | 03/07/2006 |
| 6949667 | Alkenylphosphonic ester and preparation process thereof Novel alkenylphosphonic acid esters of the following general formula (I): R1CH═CR2[P(O)(OCR3R4CR5R6O)] (I) and a simple process for the preparation thereof are provided by t... | 09/27/2005 |
| 6936215 | Processing methodology for the rational control of bilayer numbers leading to high efficiency production of lipid microtubules The wall thickness of lipid microtubules are controlled by selecting a methanol/water system and determining the required amount of a lipid to form the desired wall thickness. The lipid is dissolved in a small portion of the heated methanol and that clear solution i... | 08/30/2005 |
| 6909010 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids A facile synthesis of symmetric esters of C1-C10 alkylenebisphopsphonic acids is disclosed in which a C1-C10 alkylenebis(phosphonic dichloride) is reacted with an alcohol in the presence of a catalytic amount of 1H-tetrazo... | 06/21/2005 |
| 6890676 | Fullerene based proton conductive materials A fullerene-based proton conductor including a proton conductive functional group connected to the fullerene by an at least partially fluorinated spacer molecule. Also, a polymer including at least two of the proton conductors that are connected by a linking molecul... | 05/10/2005 |
| 6740618 | Alkyl cobalt(III) dioximates and process for forming the same This invention is directed to alkyl cobalt (III) dioximates and methods for making these dioximates. The alkyl cobalt (III) dioximate has the following structural formula: wherein R1, and R2 are ind... | 05/25/2004 |
| 6727378 | Process for the production of a phosphorus-containing organic compound A process for the production of an organic phosphorus-containing product, which comprises reacting a phosphorus-containing oxide with an unsaturated hydrocarbon in the presence of a boron-containing compound at a temperature of less than or equal to 50° C. ... | 04/27/2004 |
| 6713623 | Tetraphosphonate bicyclic trisanhydrides Disclosed are novel bicyclic tris(anhydride)s useful as intermediates in the synthesis of biologically active compounds, and the compounds which may be synthesized from such intermediates. ... | 03/30/2004 |
| 6677374 | Nitrate esters and methods of making same Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effective amount of a th... | 01/13/2004 |
| 6632957 | Process for the preparation of (dialkylphosphono)alkyl (meth)acrylate The invention relates to a process allowing the preparation of a (dialkylphosphono)alkyl (meth)acrylate, corresponding to the formula: ##STR1## by reaction of an alkyl (meth)acrylate A of formula: ##STR2## with a dialkylphosphonated alcohol B of formula: ... | 10/14/2003 |
| 6566545 | Menthol derivatives and process for preparing the same The present invention provides a menthol derivative represented by the following Formula 1 and a method for preparing the menthol derivative. The menthol derivative represented by the Formula 1 is prepared by reacting menthol and phosphorous oxychloride w... | 05/20/2003 |
| 6495720 | Method for preparing alkoxyamines from nitroxides The invention relates to a process for preparing alkoxyamines. This process consists in mixing, in an organic solvent, a metal salt, a ligand for the metal, a halocarbon compound ZX and a nitroxide, in keeping the reaction medium stirring at a temperature... | 12/17/2002 |
| 6448401 | Process for water soluble azole compounds An improved process is provided for preparing water-soluble prodrugs of triazole antifungal compounds containing a secondary or tertiary hydroxyl group. More particularly, the improved process is directed toward preparation of water-soluble triazole antif... | 09/10/2002 |
| 6417383 | Thermosensitive cyclotriphosphazene derivatives and a preparation method thereof The present invention relates to novel cyclotriphosphazene derivatives represented by Formula (1) and a preparation method thereof wherein HNA is an amino acid group selected from glycine group(--NHCH2 COO-), aminomalonic acid group(... | 07/09/2002 |
| 6326490 | Tetraphosphonate bicyclic trisanhydrides Disclosed are novel bicyclic tris(anhydride)s useful as intermediates in the synthesis of biolologically active compounds, and the compounds which may be synthesized from such intermediates.... | 12/04/2001 |
| 6215013 | Preparation of phosphonic acid derivatives A method for the preparation of alkene phosphonic acids and salts thereof, such as VDPA (vinylidene diphosphonic acid) is disclosed. The products can be produced in a stable, substantially pure form and in high yield. The method includes the azeotropic re... | 04/10/2001 |
| 6048995 | Process for the preparation of diphosphonate derivatives A process for the preparation of a compound of formula I, ##STR1## wherein R1 and R2 are independently C1-6 alkyl, R3 is hydroxy and R4 and R5 are independently C1-6 alkyl is ... | 04/11/2000 |
| 5973179 | C-15 phosphonate reagent compositions for the manufacture of compounds such as lycopene and methods of synthesizing the same The present invention describes novel phosphonate reagent compositions of the formula: ##STR1## wherein R and R'=C1 -C4 alkyl groups, or R, R'=(CH2)n (n=2 or 3) or [CH2 C(CH3)2 | 10/26/1999 |
| 5952519 | C-15 phosphonate reagent compositions for the manufacture of compounds such as canthaxanthin and methods of synthesizing the same The present invention describes novel C-15 allenic phosphonate reagent compositions of the formula: ##STR1## The invention also describes novel C-15 allylic phosphonate reagent compositions of the formula: ##STR2## The invention also descri... | 09/14/1999 |
| 5905163 | Method for preparing aminomethylphosphonate derivatives via hydrogenation of cyanophosphonate derivatives A novel process for preparing aminomethylphosphonate derivatives involves the hydrogenation of cyanophosphonate derivatives in the presence of a catalyst to produce aminomethylphosphonate derivatives.... | 05/18/1999 |
| 5886217 | Method of producing aryl-substituted, amino-acylated phosphonic-acid derivatives with the aid of metal complexes of chiral, amphiphilic ligands The invention is relates to a method of producing aryl-substituted, amino-acylated phosphonic-acid derivatives with the aid of metal complexes of chiral amphiphilic ligands in that according to the invention -N-acyl-protected, ଲ-substituted a... | 03/23/1999 |
| 5883122 | Nitrate esters and their use for neurological conditions Aliphatic nitrate esters having a sulfur or phosphorus atom ଲ or γ to a nitrate group and their congeners having efficacy as neuroprotective agents are described. Preferred nitrate esters may be synthesized by nitration of a 3-bromo-1,2-propanediol... | 03/16/1999 |
| 5861525 | Method for preparing cyanophosphonate derivatives from phosphate esters and cyanide A process for preparing cyanophosphonate derivatives involves contacting a phosphate ester and cyanide in a reaction mixture under conditions sufficient to produce a cyanophosphonate derivative. That cyanophosphonate derivative product can subsequently be... | 01/19/1999 |
