"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 7098197 | Phosphonate compounds The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and th... | 08/29/2006 |
| 7094772 | Phosphonate compounds The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and th... | 08/22/2006 |
| 7081533 | Cycloaliphatic/aromatic diphosphines and use thereof in catalysis The present invention concerns novel unsymmetrical chiral diphosphines of a mixed aliphatic-aromatic type and processes for synthesizing them, complexes of these compounds and their use as catalysts. ... | 07/25/2006 |
| 7057061 | Chiral monophosphorus compounds The present invention relates to catalysts comprising chiral monophosphorus compounds and their use, the chiral monophosphorus compounds themselves and also their precursors. ... | 06/06/2006 |
| 7034014 | Phosphonate compounds The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and th... | 04/25/2006 |
| 6800778 | Process for producing optically active naphthalene derivative and optical resolver therefor The present invention provides a method of producing an optically active form of a compound represented by the formula (I) having a steroid C17,20-lyase inhibitory activity and is useful as an agent for the prophylaxis or treatment of prostatism, tumor su... | 10/05/2004 |
| 6790928 | Process for producing polycarbonates 100 parts by weight of the polycarbonate produce by melt polycondensation of a carbonic acid diester and a dihydroxy compound and 0.0001 to 0.1 part by weight of a phosphite compound represented by following Formula (I) are formulated: | 09/14/2004 |
| 6756402 | Cyclipostins, process for their preparation and use thereof The invention relates to compounds of formula I in which R1, R2, E, X1, X2, and X3 have the meaning as described in the specification and claims, obtained by culturi... | 06/29/2004 |
| 6440891 | Catalyst comprising a complex of a metal of subgroup VIII, on the basis of a phosphonite ligand and method for hydroformylation The catalyst comprises at least one bi- or more highly dentate phosphonite ligand of the general formula I ##STR1## or salts and mixtures thereof and is useful in a process for hydroformylating compounds containing at least one ethylenically unsatura... | 08/27/2002 |
| 6426429 | Process for the preparation of hindered phosphites A process to produce organic phosphites from the group consisting of: ##STR1## wherein each R1 , R2, and R3 is independently selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, iso-propyl, n-butyl, t-b... | 07/30/2002 |
| 6310260 | Separation processes This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted rea... | 10/30/2001 |
| 6307109 | Separation processes This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar rea... | 10/23/2001 |
| 6307108 | Metal-ligand complex catalyzed processes This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more formylester products from a reaction product fluid comprising one or more unreacted unsaturated es... | 10/23/2001 |
| 6307110 | Separation processes This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more products from a continuously generated reaction product fluid comprising one or more unreacted rea... | 10/23/2001 |
| 6303830 | Metal-ligand complex catalyzed processes This invention relates to a process for separating one or more organophosphorus ligand degradation products, one or more reaction byproducts and one or more formylester products from a reaction product fluid comprising one or more unreacted unsaturated es... | 10/16/2001 |
| 6303829 | Separation processes This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, said one or more products, one or more nonpolar rea... | 10/16/2001 |
| 6294680 | Process for the production of semi synthetic statins via novel intermediates A process has been provided to produce semi synthetic statins, as for instance simvastatin with a high yield, for another statin, preferably a naturally occurring statin, as for instance lovastatin. Also a number of novel intermediate compounds, prepared ... | 09/25/2001 |
| 5962744 | Process for hydrocarbonylations in supercritical carbon dioxide A process comprising subjecting at least one compound containing at least one carbon--carbon double bond or at least one carbon--carbon triple bond, hydrogen and carbon monoxide, to a hydrocarbonylation reaction in supercritical carbon dioxide, in the pre... | 10/05/1999 |
| 5952530 | Separation processes This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, a nonpolar solvent and said one or more products, w... | 09/14/1999 |
| 5932772 | Separation processes This invention relates to a process for separating one or more products from a reaction product fluid comprising a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, a polar solvent and said one or more products, wher... | 08/03/1999 |
| 5891939 | Phosphites, process for producing them and their use Phosphites inhibitors for organic material represented by the formula: ##STR1## wherein R1, R2, R4 and R5 independently represent hydrogen atom, an alkyl group, a cycloalkyl group, an alkylcycloalkyl group,... | 04/06/1999 |
| 5889095 | Phosphites, process for producing the same and their use A phosphite stabilizer for organic material is represented by the formula (1): ##STR1## wherein R1, R2, R4 and R5 is hydrogen, alkyl, cycloalkyl, alkyl, cycloalkyl, aralkyl or phenyl; R is hydrogen or alkyl... | 03/30/1999 |
| 5874494 | Phosphites, process for producing them and their use Phosphites which are useful as a deterioration inhibitor for organic material and are represented by the following formula: ##STR1## wherein R1, R2, R5 and R6 represent a hydrogen atom, an alkyl group, a cy... | 02/23/1999 |
| 5843339 | Phosphites and their production and use Phosphites represented by the general formula (I): ##STR1## wherein R1, R2, R4 and R5 independently represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 5 to 8 car... | 12/01/1998 |
| 5830936 | Phosphites, process for producing them and their use Phosphites which are a deterioration inhibitors for organic material represented by the formula: ##STR1## wherein R1 and R2 independently represent a hydrogen atom, or certain hydrocarbyl radicals; X represents a direct bond, a ... | 11/03/1998 |
| 5786497 | Process for the preparation of phosphites A process for producing organo-phosphites is described that involves heating a di-substituted phosphorohalidite, a phenolic compound, and a polymeric amine. An especially useful polymeric amine is N,N,N'N'-tetraethyl-1,3-propanediamine. Conversions in exc... | 07/28/1998 |
| 5736599 | Diphosphites A diphosphite is provided derived from phosphorous trihalide, tetra alkyl hindered bisphenol, and a neoalkyl diol. The phosphites exhibit improved stability and are useful as thermal oxidative stabilizers for thermoplastic compositions.... | 04/07/1998 |
| 5677432 | Immunological detection of organophosphates A compound useful for forming immunoconjugates used in the detection of organophosphate pesticides is provided. The compound has the formula ##STR1## wherein X is selected from the group consisting of R--O--, R--S-- and R--NH--, where R is an optiona... | 10/14/1997 |
| 5623009 | Neo-diol phosphites as polymer stabilizers A phosphite is provided having the formula: ##STR1## wherein Y1 is an alkyl group and Y2 is selected from the group consisting of sec-butyl and tert-butyl. The phosphite exhibits enhanced stability including hydrolytic and UV st... | 04/22/1997 |
| 5618961 | Diphosphites A diphosphite is provided derived from phosphorous trihalide, tetra alkyl hindered bisphenol, and a neoalkyl diol. The phosphites exhibit improved stability and are useful as thermal oxidative stabilizers for thermoplastic compositions.... | 04/08/1997 |
| 5618962 | Diphosphites A diphosphite is provided derived from phosphorous trihalide, tetra alkyl hindered bisphenol, and a neoalkyl diol. The phosphites exhibit improved stability and are useful as thermal oxidative stabilizers for thermoplastic compositions.... | 04/08/1997 |
| 5600032 | Method for producing an unsaturated alcohol A method for producing an unsaturated alcohol having a chain structure formed by oligomerization of a conjugated alkadiene, which comprises reacting a conjugated alkadiene and water in the presence of carbon dioxide by means of a palladium compound and a ... | 02/04/1997 |
| 5576365 | Phosphorus type stabilizer and an organic material stabilized by the same An organic phosphorus compound represented by the following formula (I): ##STR1## wherein R1 and R2 independently represent alkyl having 1-8 carbon atoms, cycloalkyl having 5-8 carbon atoms, alkylcycloalkyl having 6-12 carbon at... | 11/19/1996 |
| 5523448 | Diphosphites A diphosphite is provided derived from phosphorous trihalide, tetra alkyl hindered bisphenol, and a neoalkyl diol. The phosphites exhibit improved stability and are useful as thermal oxidative stabilizers for thermoplastic compositions.... | 06/04/1996 |
| 5464889 | Phosphite antioxidants Neoalkyl phosphite provided which exhibit improved levels of stability. The phosphites are hindered and are useful in stabilizing thermoplastic compositions.... | 11/07/1995 |
| 5451623 | Neoalkyl alkylidene-2,2'-bisphenyl and biphenyl phosphite esters Neoalkyl alkylidene-2,2'-bisphenyl phosphite esters are provided. The phosphites exhibit enhanced thermal and hydrolytic stability, and are useful as additives in thermoplastic resin compositions to enhance the thermal oxidative stability thereof.... | 09/19/1995 |
| 5424348 | Neo-diol phosphites as polymer stabilizers A phosphite is provided having the formula: ##STR1## wherein Y1 is an alkyl group and Y2 is selected from the group consisting of sec-butyl and tert-butyl. The phosphite exhibits enhanced stability including hydrolytic and UV st... | 06/13/1995 |
| 5414033 | Phenyl phosphites for use as stabilizers for organic materials Novel compounds of the formula I and formula II ##STR1## in which R and R1, independently of one another, are hydrogen or C1 -C4 alkyl or together with the carbon atom to which they are attached form a 3,4-dehydrocycl... | 05/09/1995 |
| 5362898 | Bis(pentaerythritol phosphate alcohol) alkylphosphonate A bis(pentaerythritol phosphate alcohol) alkylphosphonate compound, such as one comprising an alkyl group of from about one to four carbon atoms, preferably bis(pentaerythritol phosphate alcohol) methylphosphonate, is a flame retardant compound. Such a co... | 11/08/1994 |
| 5308902 | Biphosphites Biphosphites of formula I ##STR1## wherein m is 0, 1 or 2, n is 1 to 4 or 6, R1 is hydrogen or C1 -C4 alkyl and, if m=2, the radicals R1 are identical or different, and A is the radical of an at least n-hyd... | 05/03/1994 |