Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 8134020 | Polymerization of hydroxytyrosol mediated by horseradish peroxidases The present invention provides a method of producing polyhydroxytyrosol comprising the step of reacting hydroxytyrosol monomers or derivative thereof in a mixed solution comprising an enzyme, hydrogen peroxide, and an aqueous solvent. ... | 03/13/2012 |
| 8013179 | Anionic acid-labile surfactants and methods of use Anionic acid-labile surfactants may generally comprise compounds represented by the formulas: and wherein R1 is independently selected from —(CH2)0-9 | 09/06/2011 |
| 7271283 | High refractive index, UV-curable monomers and coating compositions prepared therefrom Disclosed herein are high refractive index monomers that are curable by ultraviolet light. These monomers may be a component of curable compositions useful in the preparation of optical articles. Also disclosed is a method of synthesizing the monomers. ... | 09/18/2007 |
| 7176267 | Fluorine-containing polyether monomer, and polymer and surface treatment agent comprising the same A fluorine-containing polymer which is an active component of a surface treatment agent having excellent water- and oil-repellency is constituted by a fluorine-containing polyether monomer of the formula: wher... | 02/13/2007 |
| 7053071 | Induction of apoptosis in cancer cells The present invention provides compounds that are inducers or inhibitors of apoptosis or apoptosis preceded by cell-cycle arrest. In addition, the present invention provides pharmaceutical compositions and methods for treating mammals with leukemia or other forms of... | 05/30/2006 |
| 7049455 | Process for producing shogaols and intermediates for the synthesis thereof In accordance with the invention, an industrial process for producing shogaols useful in the fields of for example foods, flavor, pharmaceutical products, qui-pharmaceutical products and cosmetics can be provided. The invention relates to novel intermediates represe... | 05/23/2006 |
| 6987198 | Acid generator and thin film composition containing the same The present invention relates to the compounds generating strong acids (described hereafter as “acid generators”) decomposed by heat and the composition of thin film containing the same. Provided are the compounds represented by the structure of formula I and th... | 01/17/2006 |
| 6939988 | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them Novel β-aryl-α-oxysubstituted alkylcarboxylic acids of the formula (I) and compositions containing them. The compounds have hypolipidemic, antihyperglycemic uses. ... | 09/06/2005 |
| 6864017 | Method of preparing lithium complex salts for use in electrochemical cells The invention relates to a method of preparing lithium complex salts and their intermediaries and to the use of these in electrolytes. ... | 03/08/2005 |
| 6756409 | Phenoxyphenyl alkanesulphonates The invention relates to novel phenoxyphenyl alkanesulphonates, processes for their preparation, their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment of states of pain and neurodegenerative disorders. | 06/29/2004 |
| 6747166 | Process for preparing carotenoid polyene chain compounds and intermediates for preparing the same The present invention provides an intermediate compound used for synthesis of polyene chain structure, that is an important moiety of carotenoid compounds, a process for preparing the same, and carotenoid polyene chain compounds prepared by using the intermediate, a... | 06/08/2004 |
| 6630509 | Phenalkyloxy-phenyl derivatives The present invention relates to certain phenalkyloxy-phenyl derivatives of formula (I) ##STR1## and analogs, to a process for preparing such compounds, which compounds have utility in treating clinical conditions associated with insulin resistance, ... | 10/07/2003 |
| 6268520 | Tricyclic compounds Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.... | 07/31/2001 |
| 6194586 | Selective sulphonation of the primary alcohol of a diol containing both primary and secondary alcohols This invention discloses an efficient process for selectively sulfonating the primary alcohol of a diol containing both primary and secondary alcohols.... | 02/27/2001 |
| 6130346 | Process for preparing an organic compound from an oxirane-containing compound in the presence of a tris(triaminophosphoranylideneamino)phosphine oxide A process for preparing an organic compound, comprising conducting an organic reaction in the presence of a phosphine oxide represented by formula (1); ##STR1## where R1 is the same or different and each represents a hydrogen or hydro... | 10/10/2000 |
| 6037378 | Phenylacetic acid derivatives, processes and intermediates for their preparation, and compositions comprising them Phenylacetic acid derivatives of the formula I ##STR1## where the substituents and the index have the following meanings: X is NOCH3, CHOCH3, CHCH3 ; Y is O, NR R1,R independently of one another are hydrogen and... | 03/14/2000 |
| 6020512 | Process and novel intermediates Novel processes and intermediates useful in the preparation of Cryptophycin compounds are disclosed.... | 02/01/2000 |
| 5973178 | Dye intermediates A compound of the formula: ##STR1## wherein: A is hydrogen, a substituted or unsubstituted C1 to C4 alkyl, a substituted or unsubstituted C1 to C4 alkoxy or a substituted or unsubstituted phenyl; W is a sub... | 10/26/1999 |
| 5814110 | Chemical compositions and use as fuel additives Distillate fuel is treated with additives whose structure match the crystal planes of the wax which crystallizes from the fuel to produce crystals below 4000 nanometres in size, suitable additive include novel sulpho-carboxylic materials particularly thei... | 09/29/1998 |
| 5705704 | Tricyclic compounds Novel tricyclic compounds of formula I as defined in the specification, a process for their preparation and their use for the preparation of optically active or racemic colchicine and thiocolchicine derivatives.... | 01/06/1998 |
| 5658951 | Diphenylcyclopropyl analogs Diphenylcyclopropyl analogs in which one or more of the phenyl rings includes alkoxy substituents including a dialkylaminoalkoxy group, an unsubstituted piperazine alkoxy group, a substituted piperazine alkoxy group, an unsubstituted piperidine alkoxy gro... | 08/19/1997 |
| 5550273 | Process for preparing fluorocarbon fluoroalkanesulfonates A process for preparing fluorocarbon fluoroalkanesulfonates comprises (a) forming a mixture comprising at least one fluoroalkanesulfonyl halide, e.g., perfluoromethanesulfonyl fluoride, at least one fluorocarbon-substituted carbinol, e.g., 1,1-dihydr... | 08/27/1996 |
| 5478960 | Process for the preparation of heterosubstituted acetals Heterosubstituted acetals of the formula ##STR1## can be obtained by reacting vinyl compounds of the formula CH2 .dbd.CH-A1 (II) with alkyl nitrites of the formula R1 --ONO ... | 12/26/1995 |
| 5468466 | Compositions of iodophenyl sulfonates for X-ray visualization of the gastrointestinal tract Disclosed are contrast agents of the formula ##STR1## contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract wherein ##STR2## Z=H, halo, C1 -C20 alkyl, cycloalkyl, ... | 11/21/1995 |
| 5466880 | Process for preparing ketone enantiomer A novel multi-step process for preparing the (4S)-enantiomer of 4-(3,4 -dichlorophenyl)-3,4-1(2H)- naphthalenone in a highly-optically pure form is disclosed. The process involved starts from the known 4-(3,4-dichlorophenyl)-4-ketobutanoic acid and procee... | 11/14/1995 |
| 5445963 | Alcohol-ester separation by recrystallization A process is disclosed for the separation of an enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene and an enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene from a first mixture containing both compounds. The process includes the steps of: (a) f... | 08/29/1995 |
| 5422367 | Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents Diphenylcyclopropyl analogs in which one or more of the phenyl rings includes substituents comprising a hydroxy group, a hydrogen atom, an acetate group or a substituted or unsubstituted alkoxy group. The compounds are useful as antiestrogens and anti-tum... | 06/06/1995 |
| 5372800 | Compositions of iodophenyl esters and iodophenyl sulfonates in film-forming materials for visualization of the gastrointestinal tract Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1##... | 12/13/1994 |
| 5312950 | Method for purification of alcohols A method for the purification of alcohols from organic soluble impurities has been discovered comprising treating the crude alcohol with a cyclic anhydride followed by an aqueous base and extracting the corresponding half-ester into aqueous solution leavi... | 05/17/1994 |
| 5304661 | Substituted-acyclic terpene compound Acyclic terpene compounds useful as intermediates for producing sarcophytol A which have an anti-carcinogenic promotor activity and anti-tumor activity, which compounds are shown by the general formula (I): ##STR1##... | 04/19/1994 |
| 5296627 | Ethylenically unsaturated poly(alkyleneoxy) surfactants Describes terminally ethylenically unsaturated poly(alkyleneoxy) surfactant compounds of the general formula, R--O--(R'O)m --(EO)n-1 --CH2 CH2 --X, wherein R is the ethylenically unsaturated hydrocarbon group, e... | 03/22/1994 |
| 5294511 | Photosensitive composition A photosensitive composition containing a compound having a group represented by formula(I) or (II), said group, when irradiated with actinic radiation, forming a carboxylic acid or a sulfonic acid: ##STR1## wherein R1 represents hydrogen,... | 03/15/1994 |
| 5292911 | Monocyclic terpene derivatives Novel monocyclic terpene derivative of the formula: ##STR1## wherein R is hydrogen atom, trimethylsilyl group or 1-ethoxyethyl group, and novel intermediates therefor. The terpene derivative (I) is a useful intermediate for preparing Sarcophytol A ha... | 03/08/1994 |
| 5268511 | Production of trifluorovinyl ethers A two step process, each of the steps being novel, for the production of trifluorovinyl ethers by reaction of a siloxane with selected acyl fluorides or carboxylic anhydrides, is disclosed. Also disclosed is a novel silyl ester intermediate.... | 12/07/1993 |
| 5262253 | Solid electrolytes derived by polymerization of vinyl sulfonate polyalkylene oxides This invention is directed to solid electrolytes containing a solid polymeric matrix derived from vinyl sulfonate polyalkylene oxides.... | 11/16/1993 |
| 5250715 | Optically active 2-methylenepentane derivative and process for preparing same The present invention provides an optically active 2-methylenepentane derivative represented by the general formula ##STR1## (wherein R1 is a protective group for hydroxyl, R3 is a protective group for hydroxyl, X is a halogen a... | 10/05/1993 |
| 5248828 | Method for preparing sulfones A method for preparing a sulfone represented by the following formula: ##STR1## wherein R' represents a lower alkyl group, an aryl group or an aryl group whose nucleus has at least one substituent selected from the group consisting of a halogen atom,... | 09/28/1993 |
| 5235084 | Method for preparing sulfones A method for preparing a sulfone represented by the following formula: ##STR1## wherein R and R' each represent a lower alkyl group, an aryl group or an aryl group whose nucleus has at least one substituent selected from the group consisting of a hal... | 08/10/1993 |
| 5216187 | Optically active 2-methylenepentane derivative and process for preparing same The present invention provides an optically active 2-methylenepentane derivative represented by the general formula ##STR1## (wherein R1 is a protective group for hydroxyl, R3 is a protective group for hydroxyl, X is a halogen a... | 06/01/1993 |
| 5210257 | Preparation of aryl compounds containing carboxyl and sulfonyl groups Novel aryl ethers, containing both a carboxylic acid and a sulfonic acid functionality; and a process for making them are described. These difunctional aryl compounds comprise: i) a carboxylic acid group or its derivative, ii) a first aromatic group bonded to ... | 05/11/1993 |