Class 558/425 - Halogen attached indirectly to the cyano group by nonionic bonding

Subclass of Class 558 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the cyano group is attached indirectly
No. of patents: 196
Last issue date: 06/22/2010

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Number	Title	Issue Date
7741507	Process for preparing Valsartan The invention relates to novel compound of formula (IV), which is an organic acid salt of N-[(2′-cyanobiphenyl-4-yl)methyl]-(L)-valine ester. This compound is an useful intermediate for process of preparation of Valsartan of formula (I), chemically known as (S)—...	06/22/2010
7576233	Method for the preparation of halogenated benzonitriles The present invention relates to a method for preparing halogenated benzonitriles by vapor phase ammoxidation at a reaction temperature in the range of 300 to 500° C. in a fixed bed reactor using a three-component catalyst. More particularly, the method of the inve...	08/18/2009
7569718	Production process of fluorinated benzonitrile The invention enables reduction of catalyst in producing tetrafluorobenzonitrile by decyanation of one cyano group of tetrafluorodicyanobenzene by using a synthetic zeolite, particularly Zeolite 3A, 4A or 5A, in the reaction. Therefore, the invention provides an ind...	08/04/2009
7316738	Milled submicron chlorothalonil with narrow particle size distribution, and uses thereof A method of milling chlorothalonil to form a sub-micron product having a narrow particle size distribution is presented. The milling involves wet milling of the chlorothalonil with high density milling media having a diameter between 0.1 mm and 0.8 mm, preferably be...	01/08/2008
7250199	Phenylcyclohexanes and a liquid-crystalline medium Novel phenylcyclohexanes of the formula I in which n is 0 to 7, Q1 and Q2 are H, or one of these radicals is alternatively CH3, r is 0, 1, 2, 3, 4 or 5, A is trans-1,4-cyclohexyle...	07/31/2007
7132561	Process for producing fluorinated dicyanobenzene An object of the invention is to provide a process for industrially producing fluorinated dicyanobenzenes using tetrachlorodicyanobenzene as a raw material. According to the present invention, fluorinated dicyanobenzene can be produced in a high yield by allowing te...	11/07/2006
6955837	Phenylcyclohexanes and a liquid-crystalline medium Novel phenylcyclohexanes of the formula I in which n is 0 to 7, Q1 and Q2 are H, or one of these radicals is alternatively CH3, r is 0, 1, 2, 3, 4 or 5, A is trans-1,4-cyclohexylene, 1,...	10/18/2005
6909023	Production method for benzenedimethanol compound To provide a novel method for producing a fluorinated benzenedimethanol compound useful as a starting material or an intermediate in the production of agricultural or medicinal chemicals in an industrially advantageous manner. A method for producing a fluorin...	06/21/2005
6861549	Production method of 4′-bromomethyl-2-cyanobiphenyl The present invention relates to a production method of 4′-bromomethyl-2-cyanobiphenyl, which includes reacting 4′-methyl-2-cyanobiphenyl with bromine in the presence of a radical initiator and an oxidant. According to the present invention, since bromine can be...	03/01/2005
6827876	Difluoromethyl ether derivative and process for producing the same A liquid crystalline compound represented by Formula (1c′): wherein R1 and R2, rings A1, A2, A3, A4 and A5, Z1, Z2	12/07/2004
6720458	Photooxidation catalyst and production process for aldehyde derivatives The present invention relates to a catalyst useful for a photooxidation reaction and also relates to a novel process for producing aldehydes, particularly aromatic aldehydes, which are useful as an intermediate for the production of agrochemical and medical preparat...	04/13/2004
6683213	Substituted aniline compounds The present invention relates to substituted aniline compounds of the formula 1 ##STR1## in which R21, R22 and R23 have the meanings indicated in the description. The compounds according to the invention are intermediates ...	01/27/2004
6680402	Benzamidoxime derivatives, intermediates and processes for their preparation, and their use as fungicides Benzamidoxime derivatives of the formula I: ##STR1## where R1 is difluoromethyl or trifluoromethyl R2 is hydrogen or fluorine R3 is C1 -C4 -alkyl which may be substituted by cyano, C1	01/20/2004
6673267	Phenylacetylene compound, liquid crystal composition, polymer, optically anisotropic product, and liquid crystal or optical element Phenylacetylene compounds are disclosed which are expected to exhibit high refractive index anisotropy, easy to mix with other liquid crystal compounds, has advantageous stability against light, and may be used as a material for producing various films an...	01/06/2004
6485799	Aniline derivatives, liquid-crystal composition containing the same, and liquid-crystal display element A aniline derivative represented by general formula (1) ##STR1## wherein R and R' represent independently each other alkyl with 1 to 10 carbon, alkoxyalkyl with 1 to 10 carbon, or hydrogen; x represents cyano, halogen, haloalkyl, haloalkyloxy, or 2-cyanoe...	11/26/2002
6468607	Naphthalene derivative and liquid crystal composition comprising the same Disclosed is a novel liquid-crystalline compound which is a naphthalene derivative useful as an electro-optical liquid crystal display material, a liquid crystal composition containing such naphthalene derivatives and a liquid crystal display device compr...	10/22/2002
6462218	Method for preparing 3-cyano-2,4-dihalogeno-5-fluoro-Benzoic acid The present invention relates to a process for preparing 3-cyano-2,4-dihalogeno-5-fluoro-benzoic acid, to intermediates for carrying out the process and to processes for preparing these intermediates....	10/08/2002
6437168	Method for production of aromatic fluorine compound A method for efficiently extracting a reaction product containing a target aromatic fluorine compound formed by the halogen exchange reaction of an aromatic chlorine compound with a fluorinating agent quickly from the reaction vessel without suffering par...	08/20/2002
6392084	Method for production of organic fluorine compound A method for the production of an aromatic fluorine compound is provided which is capable of preventing the occurrence of benzoic acid fluorides during the course of a halogenation exchange reaction or allowing removal of the benzoic acid fluorides formed...	05/21/2002
6313337	Method of making benzoyl halides and nitriles A method of making a benzoyl halide is disclosed. Into a reactor is placed a reaction mixture of a benzotrihalide and a benzaldehyde having the respective general formulas ##STR1## where each A is independently selected from halogen, CF3, R, or...	11/06/2001
6284154	Phenylcyclohexanes and a liquid-crystalline medium Novel phenylcyclohexanes of the formula I ##STR1## in which n is 0 to 7, Q1 and Q2 are H, or one of these radicals is alternatively CH3, r is 0, 1, 2, 3, 4 or 5, A is trans-1,4-cyclohexylene, 1,4-phenylene, 3-fluoro-1,4-ph...	09/04/2001
6214999	Method for preparing bromomenthyl-biphenyl derivatives The present invention relates to a process for the preparation of 4'-bromomethyl-biphenyl derivatives of the formula: ##STR1## by reacting a 4'-methyl-biphenyl derivative of the formula: ##STR2## with a brominating agent a in a hydrobromic acid/alkali met...	04/10/2001
6211399	Pressurized chlorination and bromination of aromatic compounds Disclosed is a method of adding 1 to 4 chlorine or bromine atoms to an aromatic ring of compound that has at least one electron-withdrawing groups on that ring. The aromatic compound is reacted with a chlorinating agent or a brominating agent in the prese...	04/03/2001
6187945	Process for producing cyanobenzyl compounds An industrially advantageous process for producing cyanobenzyl compounds under mild conditions from relatively easily available cyanobenzylamine having a cyano group on the benzene ring or a compound thereof which is ring-substituted with a chlorine atom,...	02/13/2001
6172225	Process for producing hydroxyarenes The invention relates to a novel process for producing thereof hydroxyarenes of the general formula (I) ##STR1## in which n represents the numbers 1, 2, 3 or 4, R represents cyano, carboxyl, formyl, nitro, halogen or represents alkyl, alkoxy, alkylthio, a...	01/09/2001
6166242	Method for producing compounds containing fluorine, in particular fluorobenzaldhydes and fluorobenzonitriles The invention concerns a method for producing compound containing fluorine, particularly fluorobenzaldehyde and fluorobenzonitrle, by a halogen exchange reaction with a compound of the formula I as fluorinating agent, defined in the specification, and a q...	12/26/2000
6149837	Phenylacetylene compound and liquid crystal composition comprising the same Provide is a novel phenylacetylene compound (1) which has a large anisotropy of refractive index, tends to be mixed with other liquid crystals, and is more advantageous in stability to light, a liquid crystal composition and a liquid crystal element usabl...	11/21/2000
6133468	Method for preparing substituted benzyl bromides Substituted benzyl bromides of the formula I ##STR1## where at least one substituent R1-5 is an electron-attracting group such as fluorine, chlorine, bromine, C1 -C4 -alkoxycarbonyl, cyano or nitro, and the other subs...	10/17/2000
6118018	Chlorination and bromination of aromatic compounds at atmospheric pressure Disclosed is a method of adding 1 to 4 chlorine or bromine atoms to an aromatic ring of compound that has at least one electron-withdrawing groups on that ring. The aromatic compound is reacted with a chlorinating agent or a brominating agent in the prese...	09/12/2000
6111114	Process for the preparation of 4-bromomethyl diphenyl compounds The compounds of the formula (I) wherein R is as defined in the disclosure, are prepared by bromination of compounds of the formula (II) by means of Br2 or HBr in the presence of H2 O2. ##STR1##...	08/29/2000
6020517	Process for production of benzonitrile and benzyl alcohol A process for producing a fluorinated benzonitrile comprising hydrogenolyzing a fluorinated dicyanobenzene substituted with 1 to 4 fluorine atoms and having the remainder which may be substituted with a chlorine atom in the presence of a catalyst to cause...	02/01/2000
6017467	Propiolonitrile derivatives and liquid crystal compositions comprising the same A propiolonitrile derivative of formula (I) ##STR1## wherein n1 and n2 each independently stand for 0 or 1; A1, A2 and A3 each independently represent a 1,4-phenylene, a 1,4-phenylene substituted by one or more fluorine atoms, a trans-1,4-cyclohexyle...	01/25/2000
5981789	Preparation of nuclear chlorinated aromatic compounds Disclosed is a method of preparing an aromatic compound having the general formula ##STR1## where R is CF3, OCF3, OC2 F5, CN, NCO, or COCl, m is 0, 1, or 2, n is 0, 1, or 2, q is 1 or 2, and q+m+n is an int...	11/09/1999
5976408	Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device An acrylonitrile derivative expressed by the following general formula I, a composition comprising the derivative and having an improved viscosity and optical anisotropy, and a liquid crystal display device: ##STR1## wherein rings A1 to A	11/02/1999
5977397	Removal of an impurity from a mixture with a codistillant Disclosed is a method of removing an acid halide, anhydride, or ester impurity from a mixture with a desired product with which it codistills. At least about a stoichiometric amount of a primary or secondary amine having a boiling point at least 10° C. h...	11/02/1999
5952386	Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen...	09/14/1999
5942648	Naphthalene derivatives Naphthalene derivatives of the fomula I ##STR1## in which: R1 is an alkyl or alkenyl radical which is unsubstituted, monosubstituted by CH or CF3 or monosubstituted by halogen and has 1 to 15 carbon atoms, it also being possible...	08/24/1999
5910617	Process for the preparation of aliphatic or cycloaliphatic chlorides The process according to the invention consists in preparing chlorides of aliphatic or cycloaliphatic hydrocarbons by reacting the corresponding mono- or polyalcohol with phosgene or thionyl chloride in the presence of at least one catalyst chosen from he...	06/08/1999
5891360	Phenylcyclohexanes and a liquid-crystalline medium Novel phenylcyclohexanes of the formula I ##STR1## in which n is 0 to 7, Q1 and Q2 are H, or one of these radicals is alternatively CH3, r is 0, 1, 2, 3, 4 or 5, A is trans-1,4-cyclohexylene, 1,4-phenylene, 3-fluoro-1...	04/06/1999
5866709	Process for making aromatic nitriles Disclosed is a process for making an aromatic nitrile by reacting a benzotrichloride with an ammonium halide in the presence of an oxygen-donating initiator at a temperature of about 150° to about 250° C. An optional catalyst of a metal oxide or a metal...	02/02/1999

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Class 558/425 - Halogen attached indirectly to the cyano group by nonionic bonding