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| Number | Title | Issue Date |
| 7390899 | Process for the synthesis of high purity 3,5-diamino-6-(2,3-dichlorophenyl) (1,2,4-triazine) The present invention relates to a new process for the synthesis of high purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine of formula (I) using 2,3-dichlorobenzoyl cyanide and an aminoguanidine salt as starting materials. 2,3-dichlorobenzoyl cyanide is reacte... | 06/24/2008 |
| 7317066 | Liquid crystal polymers Liquid crystal polyester derived from phenylene-naphthalene monomers and one or more comonomers display an improved balance of properties, including low melt viscosity, fast cycle time in molding, very low mold shrinkage, high tensile and/or flexural strength, solve... | 01/08/2008 |
| 7056640 | Sulfonydiazomethanes, photoacid generators, resist compositions, and patterning process Sulfonyldiazomethane compounds containing a long-chain alkyl- or alkoxy-naphthyl group are novel and useful as photoacid generators. Chemical amplification type resist compositions comprising the same are suited for microfabrication because of many advantages includ... | 06/06/2006 |
| 7034045 | Monofluoroalkyl derivatives The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders. ... | 04/25/2006 |
| 7026094 | Substituted oxime derivatives and the use thereof as latent acids New oxime sulfonate compounds of the formula (I) and (II), wherein R1 is C1-C12alkyl, C1C4haloalkyl, hydrogon, OR9, NR10R11, SR12 or is phenyl which is unsubstituted o... | 04/11/2006 |
| 6900353 | Cyclopentyl sulfonamide derivatives The present invention provides compounds of formula (I): useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders. ... | 05/31/2005 |
| 6699904 | PPAR agonists PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-c... | 03/02/2004 |
| 6515162 | Method of preparing retroviral protease inhibitor intermediates Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective meth... | 02/04/2003 |
| 6485886 | Oxime derivatives and the use thereof as latent acids New oxime derivatives of formula (I) or. (II), wherein m is 0 or 1; R1 inter alia is phenyl, naphthyl, anthracyl, phenanthryl or a heteroaryl radical; R'1 is for example C2 -C12 alkylene, phenylene, naphthylene;... | 11/26/2002 |
| 6362230 | Sulphonamide derivatives The present invention provides novel sulphonamide derivatives which are useful for potentiating glutamate receptor function in a mammal requiring treatment, processes for their preparation, and pharmaceutical compositions containing them.... | 03/26/2002 |
| 6306840 | Cell adhesion inhibitors The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of us... | 10/23/2001 |
| 6174922 | Sulphonamide derivatives The present invention provides novel sulphonamide derivatives which are useful for potentiating glutamate receptor function in a mammal requiring treatment, processes for their preparation, and pharmaceutical compositions containing them.... | 01/16/2001 |
| 6165237 | Fuel and lubricant additives Compounds of the general formula I Z--CH2 --NY2-n Hn (I) where n is 0 or 1, z is a straight-chain or branched polyalkyl radical having a number average molecular weight of from about 150 to 40,000, and Y is... | 12/26/2000 |
| 6063953 | Chemical-sensitization photoresist composition Disclosed are novel high-sensitivity positive- and negative-working chemical-sensitization photoresist compositions capable of giving a highly heat-resistant patterned resist layer of high resolution having excellently orthogonal cross sectional profile w... | 05/16/2000 |
| 6020515 | Process for the preparation of malononitrile A novel process for the preparation of malononitrile which involves subjecting a (2-cyano-N-alkoxy)acetimidoyl halide to a high-temperature treatment.... | 02/01/2000 |
| 6004724 | Oxime sulfonates and the use thereof as latent sulfonic acids New oximsulfonate compounds of the formulae I or II, ##STR1## wherein m is 0 or 1; x is 1 or 2; R1 is, for example phenyl, which is unsubstituted or substituted or R1 is a heteroaryl radical that is unsubstituted or substituted,... | 12/21/1999 |
| 5968978 | Biphenylsulfonylcyanamides, process for their preparation, and their use as medicament Compounds of the formula I ##STR1## in which the symbols have the meanings indicated in the claims, have outstanding antiarrhythmic properties. They exhibit a cardioprotective component. They can inhibit or greatly decrease, in a preventive manner, ... | 10/19/1999 |
| 5932766 | Process for the preparation of substituted keto-enamines The present invention discloses a process for the preparation of a compound having formula 4: ##STR1## The process comprises the step of reacting an enolate having the formula: ##STR2## with a Grignard reagent. The enolate salt is formed in situ... | 08/03/1999 |
| 5859279 | Compound and process A process for the preparation of a compound of formula (VI), optionally in enantiomerically-enriched form (R or S), comprises chemoselective reduction of a novel compound of formula (V), wherein Ar1 and Ar2 are independently selected... | 01/12/1999 |
| 5846999 | Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones The compounds of the formula: ##STR1## wherein R1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl or polyfluoroalkyl; R2 and R3 are, independently, hydrogen or an acyl substituent ... | 12/08/1998 |
| 5834618 | Process for the preparation of 3-amino-2-hydroxy-4-phenylbutyronitrile derivatives 3-Amino-2-hydroxy-4-phenylbutyronitrile derivatives represented by the formula (3) may be prepared by reacting an aminoaldehyde derivative represented by the formula (1) with a cyanohydrin derivative represented by the formula (2) in the presence of a met... | 11/10/1998 |
| 5763639 | Process for producing quarternary glycine nitriles A process for preparing quaternized glycine nitriles of formula I ##STR1## comprising reaction of the corresponding precursor amine, aldehyde, hydrocyanic acid or alkali metal cyanide, and subsequent quaternization with an alkylating agent, wherein t... | 06/09/1998 |
| 5703266 | 3-substituted para-aminophenols The invention concerns the use of a 3-substituted para-aminophenol as an oxidation dye precursor for dyeing keratinous fibres, in particular human hair. The 3-substituted para-aminophenol has formula: ##STR1## where R1 represents alkyl, al... | 12/30/1997 |
| 5637770 | Hexa-cyclic compound A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-... | 06/10/1997 |
| 5631405 | Method of forming amino acid-derived diaminopropanols useful as chemical intermediates for protease-inhibitors The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized. This method incl... | 05/20/1997 |
| 5629442 | Process for producing -hydroxyiminophenylacetonitriles A process is disclosed to produce an -hydroxyiminophenylacetonitrile of the general formula [II]: ##STR1## wherein R1, R2, R3 and Z are each as defined in the specification, characterized in that a crude nitril... | 05/13/1997 |
| 5618966 | Method forming protease inhibitor synthetic intermediates The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized. This method incl... | 04/08/1997 |
| 5599994 | Amino acid-derived diaminopropanols The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized. The method inclu... | 02/04/1997 |
| 5571942 | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor.... | 11/05/1996 |
| 5543573 | Hydrazinecarboxyamide derivatives, a process for production thereof and uses thereof The present invention relates to a hydrazinecarboxamide derivative of the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, which has a wide insecticidal spectrum at a low dosage, a process for pr... | 08/06/1996 |
| 5530014 | Cyclohexadiene derivatives The cyclohexadiene derivatives are prepared by reaction of cyclohexanones with amines and subsequent dehydration. The compounds are suitable as active compounds in medicaments on account of their property of being selective modulators of calcium channel-d... | 06/25/1996 |
| 5523454 | Ortho-substituted phenylacetamides Ortho-substituted phenylacetamides I ##STR1## (R1 =H, alkyl, cycloalkyl, alkenyl, alkynyl, phenylalkynyl, alkoxyalkyl, alkoxycarbonyl, phenyl, phenylalkyl, phenylalkenyl or phenoxyalkyl, 5- or 6-membered heterocycle with 1-3 hetero atoms t... | 06/04/1996 |
| 5498746 | Process for the preparation of 5,6-dihydroxyindole and intermediate compounds Process for the preparation of 5,6-dihydroxyindole, wherein the compound of formula: ##STR1## in which R' denotes a hydrogen atom or an optionally substituted benzyl radical, is subjected either to the action of hydrogen under pressure or to a h... | 03/12/1996 |
| 5498745 | Substituted di-t-butylphenols Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents.... | 03/12/1996 |
| 5492641 | ଲ-aminonitriles and N-alkyl-1,3-propylenediamines and their use as fuel additives and lubricant additives ଲ-Aminonitriles of the following formula I ##STR1## where R1 is an aliphatic hydrocarbon radical having alkyl side groups and a number average molecular weight of from 250 to 5,000 and R2, R3 and R4, ... | 02/20/1996 |
| 5476960 | 댚minonitriles derived from reaction of carbonyl compounds and fatty aklyl alkylene diamines An -aminonitrile compound derived from the reaction, in the presence of a cyanide source of (1) a bisulfite adduct of a carbonyl compound selected from the group consisting of an aldehyde and a ketone with (2) a fatty alkyl alkylene diamine contain... | 12/19/1995 |
| 5475138 | Method preparing amino acid-derived diaminopropanols The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized. This method incl... | 12/12/1995 |
| 5457131 | Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, 2-hydrocarbyl sulfonamidomethyl and derivatives thereof as therapeutic agents The present invention relates to cyclopentane heptanoic or cyclopentane heptenoic acid, 2-hydrocarbyl sulfonamidomethyl, and derivatives thereof, useful as therapeutic agents. In particular, the therapeutic agents of this invention are useful as ocular hy... | 10/10/1995 |
| 5451607 | Hydrazone derivatives, process for producing same, insecticides and/or acaricides containing same as active ingredient and intermediate compounds thereof There are disclosed hydrazone derivatives of the general formula [I]: ##STR1## wherein R1 is halogen, etc.; R2 is hydrogen or C1 -C6 alkyl, etc.; R3 is hydrogen or C1 -C6 alkyl, ... | 09/19/1995 |
| 5416111 | Cyano-containing n-phenyl-amino-terminated non-peptidyl -succinamidoacyl aminodiols as anti-hypertensive agents Non-peptidyl compounds characterized generally as -succinamidoacyl aminodiols containing a cyano group and having an N-phenyl-amino-type group at the N-terminus are useful as renin inhibitors for the treatment of hypertension.... | 05/16/1995 |
