3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 7226719 | Limited play data storage media and coating formulations thereon The present invention provides a formulation for a reactive dye layer for a limited-play optical storage medium, the reactive formulation including at least one carrier material or curable acrylate monomer, at least one reactive material disposed within the carrier ... | 06/05/2007 |
| 7208142 | Indanylidene compounds Novel indanylidene compounds can be used as UV-A filters in cosmetic compositions for protecting skin and hair and for technical applications. ... | 04/24/2007 |
| 7166750 | Process for the preparation of 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone is produced by reacting 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester or 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxylic acid... | 01/23/2007 |
| 7049271 | Phenyl-substituted 2-enamino-ketonitriles The present invention relates to novel phenyl-substituted 2-enamino-ketonitriles of the formula (I): in which Ar, X, Z, Y and K are each as defined in the description, to a plurality of pro... | 05/23/2006 |
| 7049458 | Process for producing β-ketonitrile compound A process comprising reacting an aliphatic carboxylic ester compound with acetonitrile in the presence of a metal alkoxide to yield a metal salt of a β-ketonitrile compound, subsequently transferring the salt to an aqueous medium, and neutralizing the solution to o... | 05/23/2006 |
| 6963007 | Diacetylenic materials for sensing applications Diacetylenic materials for the colorimetric detection of an analyte or exposure to certain environmental factors are disclosed as well as the polymerization reaction products of these diacetylenic compounds. ... | 11/08/2005 |
| 6899886 | Acylacetonitriles, process for preparation thereof and miticides containing the same The acylacetonitrile compound of the invention is represented by the formula (1): wherein R1 represents —C(O)ZR2; R2 represents C1-6 alkyl, C1-4 haloalkyl or the... | 05/31/2005 |
| 6509379 | Phenylacetic acid derivatives, process and intermediate products for their preparation, and their use as fungicides and pesticides Phenylacetic acid derivatives of the formula I ##STR1## where the variables are as disclosed herein, their salts, processes and intermediates for their preparation, and their use for controlling harmful fungi and animal pests.... | 01/21/2003 |
| 6485886 | Oxime derivatives and the use thereof as latent acids New oxime derivatives of formula (I) or. (II), wherein m is 0 or 1; R1 inter alia is phenyl, naphthyl, anthracyl, phenanthryl or a heteroaryl radical; R'1 is for example C2 -C12 alkylene, phenylene, naphthylene;... | 11/26/2002 |
| 6344580 | Process for the preparation of 2,2-dimethyl-5-(4-chlorobenzyl) cyclopentanone and an intermediate useful therefore There is provided a process for the prepartion of 2,2-dimethyl-5-(4-chlorobenzyl)cyclopentanone. ##STR1## a key intermediate in the production of the antifungal agent metconazole. Also provided is the intermediate compound, 5-(4-chlorobenzyl)-5-cyano-2,2-... | 02/05/2002 |
| 6331564 | Use of triaryl methane compounds for inhibiting unwanted cellular proliferation associated with inflammatory disease The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation, and in particular inflammatory diseases associated with... | 12/18/2001 |
| 6300512 | Method for producing a 1-(3-cyclopentenyloxy-4-alkoxyphenyl)-4-oxocyclohexanecar-bonitrile This invention relates to a process for converting isovanillin to substituted 4-cyano-4-(3,4-disubstitutedphenyl)cyclhexanones. These ketones are useful in preparing certain PDE4 ingibitors wherein the 1-postion keto group is converted to a carboxylic aci... | 10/09/2001 |
| 6069258 | Cosmetic preparations comprising photostable UV-A filters A cosmetic preparation which comprises a sunscreen agent for protecting the human epidermis against UV light in the range from 280 to 400 nm, which comprises, in a cosmetically suitable carrier, alone or together with compounds which absorb in the UV regi... | 05/30/2000 |
| 6028103 | Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation. The active compounds are substituted triaryl methane co... | 02/22/2000 |
| 5977123 | Oximether and acrylic acid derivatives and their use as fungicides The invention relates to novel oximether and acrylic acid derivatives of the formula (I) ##STR1## in which Z, G, Ar, E, R1 and R2 have the meanings as given in the specification, to processes for their preparation and to their u... | 11/02/1999 |
| 5968977 | Ketonitrile derivatives and antibacterial agent and drugs containing the same The present invention is directed to a ketonitrile derivative represented by the following formula (1): ##STR1## (wherein R1 is a hydrogen atom or a lower alkyl group; each of R2, R3, R4, and R5,... | 10/19/1999 |
| 5861421 | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds This invention relates to derivatives of 4,4-(disubstituted)cyclohexan-1-ones and related compounds which are useful for treating allergic and inflammatory diseases.... | 01/19/1999 |
| 5846999 | Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones The compounds of the formula: ##STR1## wherein R1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl or polyfluoroalkyl; R2 and R3 are, independently, hydrogen or an acyl substituent ... | 12/08/1998 |
| 5846907 | Herbicidally active pyrazol-4-ylbenzoyl compounds Pyrazol-4-ylbenzoyl compounds of the formula I ##STR1## where Z is a 5- or 6-membered heterocyclic saturated or unsaturated radical, Q is a pyrazole ring and L and M are as defined in the specification, their use as herbicidal compounds and to proces... | 12/08/1998 |
| 5846906 | Herbicidally active phenyldiketone compounds Herbicidally active phenyldiketone compounds of the formula I ##STR1## in which the substituents have the following meanings: L and M are hydrogen, C1 -C6 -alkyl, C2 -C6 -alkenyl, C2 -C6 | 12/08/1998 |
| 5804532 | Herbicidal 2-cyano-1,3-diones Herbicides derived from 2-cyano-1,3-diones have the formula: ##STR1## wherein R, R1, R2 R3, R4 and R5 are as defined in the description. The compounds are intended for use pre- and post-emergence... | 09/08/1998 |
| 5650511 | Process for the preparation of 9-deazaguanine derivatives Derivatives of 9-deazaguanine are prepared by reacting an aldehyde or ketone with a dialkylaminomalonate to form the corresponding enamine. The enamine is then reacted with a base to form a cyclic pyrrole. The cyclic pyrrole is reacted with an urea compou... | 07/22/1997 |
| 5571942 | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor.... | 11/05/1996 |
| 5543549 | Process for the preparation of a substituted 2,5-Diamino-3-Hydroxyhexane Intermediates and processes are disclosed which are useful for the preparation of a substantially pure compound of the formula: ##STR1## wherein R6 and R7 are each hydrogen or R6 and R7 are independently se... | 08/06/1996 |
| 5476935 | Dyes for use in thermal dye transfer Dye-donor element for use according to thermal dye transfer comprising least one dye corresponding to the general formula (I): ##STR1## wherein Z is --CN, --COOR1 or --CONR2 R3 ; R1 is --H, (cyclo)alkyl, or... | 12/19/1995 |
| 5446067 | Oxime ethers and fungicides containing them Oxime ethers of the formula ##STR1## wherein m, G, R, R1, X, Y, and Z are as defined herein and fungicides containing these compounds.... | 08/29/1995 |
| 5426226 | Intermediates for making ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor. An intermediate for preparing the novel compounds have the following formula: ... | 06/20/1995 |
| 5380755 | Alkyl and alkylbenzyl ethers of substituted hydroquinones The present invention provides alkyl and alkylbenzyl ethers of substituted hydroquinones and pharmaceutical compositions containing them. The present invention further provides methods of using these compounds and compositions to inhibit monoamine oxidase... | 01/10/1995 |
| 5286893 | Alkenoic acid compounds for mechanism-based inactivation of dehydropeptidase activity Alkenoic acid compounds are described. The compounds which are dehydropeptidase inactivators contain a ##STR1## moiety which is substituted with a halomethylene or a cyano moiety as R3. The enzyme deprotonates the alpha --CH2 gr... | 02/15/1994 |
| 5283352 | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same Catechol compounds of formula I ##STR1## where R1, R2, R3 and X are as described herein are effective Catechol-O-methyltransferase inhibitors.... | 02/01/1994 |
| 5247119 | Phenylacetonitrilehydroxyalkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives A class of substituted phenylacetonitrilehydroxyalkylaminoalkyl-ortho-substituted aryl compounds having immunosuppressive properties is described. Compounds of this class would be useful in reducing recipient rejection of transplanted organs and for ... | 09/21/1993 |
| 5235068 | Process for producing acylaromatic compounds Acylaromatic compounds ##STR1## (Q: aromatic compound residue; R: straight, branched or cyclic aliphatic group, aromatic group or araliphatic group) are prepared in high yield by a reaction, in the presence of a boron trifluoride complex catalyst, of... | 08/10/1993 |
| 5234894 | Carbonyl acetonitrile derivative and herbicide containing it as an active component A cyanoketone derivative of the following formula (1) ##STR1## wherein A1 is a substituted or unsubstituted phenyl or naphthyl group or a substituted or unsubstituted heterocyclic group; each of X1, X2 and X3 is... | 08/10/1993 |
| 5223536 | 1,4-diaryl-1-cyclopropyl-4-substituted butanes as insecticides and acaricides The 1,4-diaryl-1-cyclopropyl-4-substituted butane pesticides of the following formula are effective as insecticides and acaricides: ##STR1## in which X and Y are independently hydrogen, halogen, alkyl, alkoxy, cycloalkylalkoxy, alkylcarbonyl, alkoxyc... | 06/29/1993 |
| 5200426 | Inhibitors of neutral endopeptidase/CALLA as chemotherapeutic agents The present disclosure relates to inhibitors of neutral endopeptidase (NEP) which are proposed as novel agents for the treatment of CALLA+ positive cancers as well as other conditions such as hypertension.... | 04/06/1993 |
| 5190999 | -carbonylphenylacetonitrile derivatives as stabilizers for organic materials Compositions comprising an organic material liable to oxidative, thermal and/or actinic degradation and at least one compound of the formula I ##STR1## are described in which n is 1-6, R, R1, R2, R3 and R4 ... | 03/02/1993 |
| 5182401 | Preparation of 3-amino-2-(het)aroyl-acrylic acid derivatives A process for the preparation of a 3-amino-2-(het)aroyl-acrylic acid derivative fo the formula ##STR1## in which Y represents a nitrile, or an ester group, --COOR1, or an acetyl group, where R1 denotes C1 -C4 | 01/26/1993 |
| 5175170 | ଲ-amino acid derivatives Non-peptidyl compounds characterized generally as cycloalkyl/cycloalkylkyl-N-terminal amino hydroxy ଲ-amino acid derivatives are useful as renin inhibitors for treatment of hypertension. Compounds of particular interest of the formula ##STR1## ... | 12/29/1992 |
| 5147892 | Benzyl ketones and fungicides containing them Benzyl ketones of the formula ##STR1## where X is CH or N, Y is O or NR4, R1, R2 are H or alkyl, R3 is halogen, cyano, nitro, alkyl, cycloalkyl, alkoxy, haloalkyl, arylalkyl, arylalkoxy, aryloxy or aryl, and the... | 09/15/1992 |
| 5142091 | , ଲ-unsaturated ketones and ketoxime derivatives The present invention provides an , ଲ-unsaturated ketone and ketoxime derivative represented by the formula ##STR1## wherein Y is oxygen atom or hydroxyimino group, Z is cyano or alkoxycarbonyl group, R1 and R2 are ... | 08/25/1992 |