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Class 558/401 - Benzene ring and cyano connected by a chain consisting of two carbons multiple bonded to each other


Subclass of Class 558 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein a chain consisting of two carbons multiple
No. of patents: 121
Last issue date: 04/26/2011


1        
NumberTitleIssue Date
7932415Process for manufacturing entacapone
New processes for manufacturing entacapone are provided. ...
04/26/2011
7750177Process for the preparation of entacapone
A process for the preparation of entacapone, in particular as the polymorphic form A, comprising the preparation of a compound of formula (V), wherein R is C1-C6 alkyl, by condensation of N,N-diethy...
07/06/2010
7592475Branched alpha-cyanostilbene fluorophores
A branched α-cyanostilbene fluorescent materials with a new structure useful to the organic electroluminescence display (OELD), which includes the organic substance in the state of powder, liquid and film with the stilbene core structure and the terminal branched p...
09/22/2009
7563922Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]amino]benzonitrile of formula (I), a N-oxide, a pharmaceutically acceptable acid addition salt, a quaternary amine or a stereochemically isomeric form thereof are pr...
07/21/2009
74767533-aryl-2-cyano-3-hydroxy-acrylic acid derivatives
Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R1 is hydrogen, C1-C20alkyl; C1-C20alkoxy; CF3; C6-C10aryl; or a radical of form...
01/13/2009
7385072Methods for the preparation of Entacapone
The invention disclosed in this application relates to an improved process for the preparation of Entacapone. In one embodiment the process involves: (i) reacting a 3-alkoxy-4-hydroxy-5-nitrobenzadehyde with N,N-diethylaminocyanoacetamide in the presence of a mild a...
06/10/2008
7317066Liquid crystal polymers
Liquid crystal polyester derived from phenylene-naphthalene monomers and one or more comonomers display an improved balance of properties, including low melt viscosity, fast cycle time in molding, very low mold shrinkage, high tensile and/or flexural strength, solve...
01/08/2008
7255874Biocompatible polymers and adhesives: compositions, methods of making and uses related thereto
Biocompatible polymers and adhesives have a cyanoacrylic core and other substituents such as therapeutic agents, targeting moieties, imaging agents, amino acid residues or other organic moieties. Exemplary uses of inventive compositions include use as sealants and a...
08/14/2007
7097789Thermoplastic containers exhibiting excellent protection to various ultraviolet susceptible compounds
Novel thermoplastic articles that contain novel ultraviolet absorbing compounds that are liquid in nature, are extremely low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat any discoloring wi...
08/29/2006
7094918Low-color ultraviolet absorbers for thermoplastic and thermoset high UV wavelength protection applications
Novel ultraviolet absorbing compounds that are liquid in nature, are low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat such discoloring), and are highly effective in providing protection in...
08/22/2006
6936735Photostable cationic organic sunscreen compounds and compositions obtained therefrom
Compounds of Formula I: wherein R, R1 and R2 are each independently hydrogen or linear or branched C1 to C10 alkyl, or linear or bra...
08/30/2005
6891058Low-color ultraviolet absorber compounds and compositions thereof
Novel ultraviolet absorbing compounds that are liquid in nature, are extremely low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat such discoloring), and are highly effective in providing pro...
05/10/2005
6680390Use of substituted vinyl-tetrahydronaphthalenes and vinyl-benzotetrahydropyrans as light protection agents
The invention relates to the use of compounds of the formula I ##STR1## in which X is the divalent radical of oxygen, a carbonyl radical, optionally aliphatically substituted imino or the radical .dbd.CR9 R10, Y is a carbonyl grou...
01/20/2004
6559216Low-color ultraviolet absorber compounds and compositions thereof
Novel ultraviolet absorbing compounds that are liquid in nature, are extremely low in color (and thus permit use without the concomitant necessity of adding large amounts of other coloring agents to combat such discoloring), and are highly effective in pr...
05/06/2003
6555702Protein kinase inhibitor
A compound of the formula I: ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy, alkoxy of 1-6 carbon atoms --CO2 Z, --O(CH2)m CO2 Z, --...
04/29/2003
6555287Non-subliming, difunctionalized ultraviolet dyes for use in anti-reflective coatings
An improved light attenuating compound for use in the production of microdevices is provided. Broadly, the light attenuating compound is difunctional and can be directly incorporated (either physically or chemically) into photolithographic compositions su...
04/29/2003
6444279Liquid crystal propene or propenyl nitrile derivatives
Acetylene derivatives of the formula I ##STR1## in which R, A1, A2, Z1, Z2, Z3, L1, L2, L3, Y, m and n are as defined herein are suitable as components of liquid-crystallin...
09/03/2002
6379590Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications
A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se...
04/30/2002
6369226Substituted benzamide inhibitors of rhinovirus 3C protease
Nonpeptide benzamide-containing inhibitors of human rhinovirus (HRV) 3C protease are described....
04/09/2002
6331564Use of triaryl methane compounds for inhibiting unwanted cellular proliferation associated with inflammatory disease
The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation, and in particular inflammatory diseases associated with...
12/18/2001
6248893Non-heterocyclic oxonol infrared radiation sensitive compounds
Infrared radiation-sensitive compounds have been found that are represented by Structure DYE as follows: ##STR1## wherein R is a secondary or tertiary amine that contains no heterocyclic group, R1 and R2 are independently carbocyclic...
06/19/2001
6207716Non-steroidal ligands for the estrogen receptor
Novel non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states....
03/27/2001
6153784Removal of halides from halide-containing nitrile mixtures
Halides are removed from halide-containing nitrile mixtures by (a) thermally treating the halide-containing nitrile mixture, (b) subsequently adding a base to the thermally treated nitrile mixture and (c) subsequently separating off the base from the nitrile mixture. Am...
11/28/2000
6107508Convergent synthesis of ଱-aryl-ଲ-ketonitriles
The present invention relates to processes for the production of ଱-aryl-ଲ-ketonitriles, which serve as synthetic intermediates in the preparation of a series of biologically important molecules such as corticotropin releasing factor (CRF) rece...
08/22/2000
6096918Aryl-acrylic acid esters
The acrylic acid esters of Formula I are useful for the delivery of organoleptic compounds, especially for flavors, fragrances, masking agents and antimicrobial compounds. They can also deliver fluorescent whitening agents....
08/01/2000
6028103Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation
The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation. The active compounds are substituted triaryl methane co...
02/22/2000
5981569Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease
The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction and particularly KDR/FLK-1 receptor signal transduction in order to regulate and/or modulate vasculogenesis and angiogenesis. The invention is bas...
11/09/1999
5951841Electroplating baths salts of aromatic hydroxy compounds and their use as brighteners
Salts of aromatic hydroxy compounds are used as brighteners in acidic electroplating baths. Furthermore, acidic electroplating baths for the electrolytic deposition of metallic layers onto shaped articles comprise, as brighteners, at least one novel salt ...
09/14/1999
5929117Immunotherapeutic agents
Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor ଱, nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory con...
07/27/1999
5888481Cinnamamides and their use as stabilizers
The invention relates to novel cinnamamides, a process for their manufacture and their use as UV absorbers. The cinnamamides of the invention may be used as UV absorbers in a variety of engineered resins such as polyamides (especially nylon 6 and 6,6), po...
03/30/1999
5877219Non-steroidal ligands for the estrogen receptor
Described herein are non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states....
03/02/1999
5830441Photostable UV absorbent containing A-cyano cinnamyl moiety
A photostable UV absorbent with maximum absorption above 340 nm having the formula: ##STR1## wherein R is --CO(R2) or phenyl optionally substituted with lower alkyl and/or lower alkoxy; R2 is --alkyl, --O(C2+ alkyl), ...
11/03/1998
5789448Benzoylethylene derivative
Disclosed is a benzoylethylene derivative represented by the following formula (I) or a salt thereof. ##STR1## R1 to R5 : a hydrogen atom, --OR9 (R9 : a hydrogen atom, a C1 -C5 alkyl g...
08/04/1998
5741821Use of natural products and related synthetic compounds for the treatment of cardiovascular disease
Use of a compound of formula (I), wherein Ar is an aromatic ring system comprising one or more optionally substituted phenyl rings optionally linked to or fused with one or more other optionally substituted phenyl rings or one or more 5 or 6-membered, opt...
04/21/1998
5703265Monofunctional n--(2--cyanoethenyl)sulfonamides
A compound having the structure: ##STR1## is disclosed. R1 is defined in the specification. The compounds are charged control agents for use in electrostatographic toners and developers....
12/30/1997
5696243Diphenylamine compounds, polymers prepared therefrom and non-linear optics devices containing the same
Diphenylamines of the formula ##STR1## where the ring A can be benzo-fused, and D is aryl or a five-membered aromatic heterocyclyl which contains one to three hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur, in the hete...
12/09/1997
5681835Non-steroidal ligands for the estrogen receptor
Prescribed herein are novel non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states....
10/28/1997
5663410Cis-4-(2,2,3,3-tetrafluoropropoxy)-cinnamonitrile and trans-4-(2,2,3,3-tetrafluoropropoxy)-cinnamonitrile and a process for their preparation
The present invention relates to the compounds cis-4-(2,2,3,3-tetrafluoropropoxy)cinnamonitrile and trans-4-(2,2,3,3-tetrafluoropropoxy)cinnamonitrile and to a process for their preparation. The process relates to the preparation of cis-4-(2,2,3,3-te...
09/02/1997
5650511Process for the preparation of 9-deazaguanine derivatives
Derivatives of 9-deazaguanine are prepared by reacting an aldehyde or ketone with a dialkylaminomalonate to form the corresponding enamine. The enamine is then reacted with a base to form a cyclic pyrrole. The cyclic pyrrole is reacted with an urea compou...
07/22/1997
5627207Arylethenylene compounds which are useful as tyrosine kinase inhibitors
The present invention provides compounds of the formula ##STR1## wherein Y is a naphthyl, tetrahydronaphthyl, pyridyl, quinolyl, isoquinolyl or indolyl ring system, R is a moiety which is an acrylic acid, a CN-substituted acrylic acid, acrylamide, ac...
05/06/1997
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