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| Number | Title | Issue Date |
| 7803962 | Process for the resolution of racemic verapamil A new process is described for the resolution of racemic verapamil, which allows the desired enantiomer to be obtained in high yields and with high enantiomeric purity. The process uses optically active 2,3-bis[(2-fluorobenzoyl)oxy]butanedioic acid as the resolving ... | 09/28/2010 |
| 7301044 | Preparation of chiral amino-nitriles A process and intermediates for producing 3-amino nitrites. The process involves resolving an enantiomeric mixture of chiral 3-amino nitrites in the presence of a chiral acid in a solvent system to produce a chiral 3-amino nitrile salt. The process may further compr... | 11/27/2007 |
| 7232845 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 06/19/2007 |
| 7183443 | Process for the preparation of enantiomerically enriched compounds Process for the preparation of enantiomerically enriched amino aldehydes and amino alcohols, wherein a corresponding enantiomerically enriched amino nitrile is subjected to hydrogenation in the presence of hydrogen, a hydrogenation catalyst, preferably a Pd-catalyst... | 02/27/2007 |
| 7097848 | Synergistic insecticidal mixtures The invention relates to insecticidal mixtures comprising the compound of the formula (I) and at least one further known active compound selected from the group consisting of abamectin, emamectin or emamectin ben... | 08/29/2006 |
| 7091233 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 08/15/2006 |
| 7022869 | Methods of asymmetrically synthesizing enantiomers of casodex, its derivatives and intermediates thereof Methods of synthesizing pure enantiomers of acylanalides such as Casodex® (bicalutamide) and its derivatives utilizing a compound having a ring structure that, when opened, provides a substituent having the structure of Formula I: | 04/04/2006 |
| 6994866 | Combinations of active ingredients, which exhibit insecticidal and acaricidal properties The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in... | 02/07/2006 |
| 6730803 | Synthetic intermediate for epothilone derivative and production method thereof The β-keto ester compound, β-hydroxy acid compound and acetonide form of a 1,3-diol derivative of the formulas (I), (V) and (VIII) wherein each symbol is as defined in the specification, are useful as a synthetic inter... | 05/04/2004 |
| 6583306 | Methods of asymmetrically synthesizing enantiomers of Casodex, its derivatives and intermediates thereof Methods of synthesizing pure enantiomers of acylanalides such as Casodex.RTM. (bicalutamide) and its derivatives utilizing a compound having a ring structure that, when opened, provides a substituent having the structure of Formula I: ##STR1## wherei... | 06/24/2003 |
| 6465684 | Process for the separation of a mixture of enantiomers A diastereomer complex obtained via a process for the separation of enantiomers is disclosed, wherein separation can be rapidly effected such that enantiomers are obtained with high e.e. values. The process permits the separation of mixtures of enantiomer... | 10/15/2002 |
| 6235927 | Process for the separation of a mixture of enantiomers A diastereomer complex obtained via a process for the separation of enantiomers is disclosed, wherein separation can be rapidly effected such that enantiomers are obtained with high e.e. values. The process pets the separation of mixtures of enantiomers i... | 05/22/2001 |
| 6184381 | Process for preparing optically active compounds This document describes a novel and practically excellent process for the preparation of optically active compounds, such as optically active alcohols or amines which are useful for various applications, for example, as synthetic intermediates of pharmace... | 02/06/2001 |
| 5929279 | Preparation of Bisoximes A process for the preparation of largely isomerically pure -bisoximes of the formula Ia R1 O--N.dbd.CR2 --CR3 .dbd.N--OR4 Ia where the groups R1 O-- and R2 on the N.dbd.C bond are cis to ... | 07/27/1999 |
| 5910601 | Chiral nitriles, their preparation and their use for the manufacture of verapamil and analogues The subject invention concerns a process for preparing a single enantiomer, either R or S, of R'--NH--(CH2)3 --C(Ar)(CN)--R. The process is particularly useful for preparing verapamil, and analogues thereof, in single enantiomeric fo... | 06/08/1999 |
| 5900503 | Process for producing optically active cyanohydrins An optically active cyanohydrin represented by the following general formula (1): ##STR1## wherein each of R1 and R2 is a hydrogen atom or an amino-protecting group, and the configurations relating to the carbon atoms at the *2-position and *3-p... | 05/04/1999 |
| 5892093 | Resolution A reproducible process for preparing a substantially single enantiomer (R or S) of 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexanoic acid, or an analogue thereof, thereby providing single enantiomer acid for the first time, proceeds by means of a classical... | 04/06/1999 |
| 5886207 | Optically active compound of flubrocythrinate, a process for preparing the same This invention relates to optically active compounds of Flubrocythrinate, their preparations and uses. The insecticidal and miticidal activities of the optically active compounds of the present invention are apparently higher than that of mixture racemic ... | 03/23/1999 |
| 5821369 | Racemisation process A process for the racemization of an enantiomerically-enriched compound of formula (3), comprises treatment of enantiomerically-enriched (3) with a base to obtain anion (4), optionally in protonated form, which is then combined with CH2 =CH--Y | 10/13/1998 |
| 5650524 | Process for preparing (R)-3-amino-5-methoxychroman A process for preparing (R)-3-amino-5-methoxychroman is provided. The process comprises the steps of (i) dissolving racemic 3-amino-5-methoxychroman and L(+)tartaric acid in water to form the tartrate salt; (ii) heating the solution until a clear solution... | 07/22/1997 |
| 5648386 | Separation of enantiomers of cimaterol, (-)-cimaterol and the use thereof in pharmaceutical compositions and animal feeds The invention relates to the separation of enantiomers of cimaterol, (-)-cimaterol, the addition salts thereof and processes for preparing them and their use in pharmaceutical compositions and animal feeds.... | 07/15/1997 |
| 5493047 | Method of preparing optically active cyanohydrin derivatives The invention relates to a method of preparing an optically active cyanohydrin carboxylic acid ester from an optically active cyanohydrin of opposite configuration, wherein said starting cyanohydrin is converted with a carboxylic acid in the presence of a... | 02/20/1996 |
| 5457224 | Resolution of racemic verapamil A process for the resolution of racemic verapamil which comprises reacting the free base of the compound with optically active dibenzoyltartaric acid or ditoluoyltartaric acid in the molar ratio from 1:1 to 1:2 in a methanol/water mixture in the ratio fro... | 10/10/1995 |
| 5395957 | Separation of enantiomers of cimaterol, (-)-cimaterol and the use thereof in pharmaceutical compositions and animal feeds The invention relates to the separation of enantiomers of cimaterol, (-)-cimaterol, the addition salts thereof and processes for preparing them and their use in pharmaceutical compositions and animal feeds.... | 03/07/1995 |
| 5334744 | Isomerisation process A process for obtaining an isomer of a compound of general formula R--CH(CN)--R' (I) wherein each of R and R' may be any organic radical linked directly or through a heteroatom to the carbon atom bearing the cyano group ... | 08/02/1994 |
| 5312957 | Enantioselective hydrocyanation of aromatic vinyl compounds The invention provides a process for enantioselective hydrocyanation of aromatic vinyl compounds which produces nonracemic mixtures of chiral, arylpropionitriles; novel carbohydrate phosphorus and nickel catalyst compositions; and optically pure (S)-... | 05/17/1994 |
| 5278338 | Racemization process for optically active carboxylic acids, salts and esters A method for racemizing an optically active carboxylic acid, or ester thereof, of the formula: ##STR1## where R1 is hydrogen, hydroxy, halo, cyano, C1 to C6 linear or branched alkoxy, amino or substituted amino or the... | 01/11/1994 |
| 5241087 | Enantiomeric enrichment of cyanohydrins A method of enantiomerically enriching chiral cyanohydrins is disclosed that involves selective cleavage of the unwanted enantiomer into its cleavage products HCN and the corresponding aldehyde or ketone by use of an enantioselective dehydrocyanation cata... | 08/31/1993 |
| 5200561 | Process for producing optically active amines Disclosed is a process for producing an optically active amine represented by the formula (IV) ##STR1## wherein R7 and R8 each denote an alkyl group, aryl group or aralkyl group, providing that they do not denote the same group ... | 04/06/1993 |
| 5153349 | Process for the preparation of cypermethrine isomers The invention relates to a process for the preparation of such isomer mixtures of cypermethrine of the Formula (I) ##STR1## wherein carbon atoms indicated by 1, 3 and stand for a chiral carbon atom and the wavy line indicates cis or trans con... | 10/06/1992 |
| 5128497 | Conversion of pyrethroid isomers to more active species Crystalline pyrethroid isomers or enantiomer pairs are converted to more pesticidally active isomers by contacting a hydrocarbon slurry of the starting isomers with an epimerization agent selected from the group consisting of 1,1,3,3-tetramethylguanidine ... | 07/07/1992 |
| 5110976 | Insecticidal composition comprising more than one active ingredient A process is disclosed for preparing a synergistic, crystalline product consisting of solely enantiomer pair 1RCisS and 1SCisR and enantiomer pair 1RTransS and 1STransR of cypermethrin in a 3:7 to 5:5 crystalline mixture, which comprises the steps of: (a)... | 05/05/1992 |
| 5015764 | Preparation of optically active aliphatic carboxylic acids A process for the separation of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process comprises (i) forming a salt solution comprising said racemic mixture of a C1 to C6 linear or branche... | 05/14/1991 |
| 5011995 | Process for the preparation of optically active secondary amines Asymmetric hydrogenation of prochiral N-aliphatic ketimines to give optically active secondary amines at a temperature from -20° to 80° C., a hydrogen pressure of 105 to 107 Pa, with the addition of catalytic amounts of an iridium ... | 04/30/1991 |
| 4997970 | Conversion of pyrethroid isomers to move active species Crystallizable pyrethroid isomers or enantiomer pairs are converted to more pesticidally active isomers by contacting a hydrocarbon slurry of the starting isomers with a base and a catalyst, the catalyst being substantially soluble in the slurry and selec... | 03/05/1991 |
| 4962223 | Process for the synthesis of the levodopa New process for the synthesis of the levodopa, L-(-)-2-amino-3-(3,4-dihydyphenyl)propionic acid, drug used in the treatment of the Parkinson's disease. The process consists in resolving with d-camphorsulfonic acid, or with a salt thereof, the d,l-2-... | 10/09/1990 |
| 4910309 | Enrichment of optical of 2-(4-aryloxyphenoxy)-propionic acids by crystallization as hydrates The optical purity of an optically active 2-(4-aryloxyphenoxy)propionic acid is enriched by formation of the hydrate of the enantiomer in excess and its removal from solution.... | 03/20/1990 |
| 4853477 | Separation of diastereomers of cyclopropanecarboxylic acid esters A process for the separation of mutually diastereomeric forms of a cyclopropanecarboxylic acid ester of the formula ##STR1## in which R1 represents hydrogen or halogen, R2 represents hydrogen or halogen, R4 represents hydr... | 08/01/1989 |
| 4782174 | Process for the preparation of certain pairs of enantiomers of -cyano-3-phenoxy-4-fluorobenzyl permethrate A process for the preparation of a mixture principally comprising the (b) 1R-3R-S+1S-3S- and (d) 1R-3S-S+1S-3R-R enantiomers of the compound -cyano-3-phenoxy-4-fluorobenzyl permethrate, comprising dissolving a mixture of all 8 ste... | 11/01/1988 |
| 4749809 | Optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof The present invention relates to an optically active borane complex represented by the general formula, ##STR1## wherein R1 represents an aryl group, R2 represents an alkyl group and a mark * means an asymmetric carbon, and a me... | 06/07/1988 |
