Class 558/210 - Benzene ring bonded directly to one of the chalcogens

Subclass of Class 558 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein one of the single bonded chalcogens is
No. of patents: 54
Last issue date: 09/20/2011

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Number	Title	Issue Date
8022239	Mechanism-based inactivators of autotaxin A novel class of compounds to inactivate autotaxin enzymes is provided. Such compounds include mono- and di-fluoromethylphenyl C12-C18 phosphodiesters and exhibit reactivity with autotaxin to ultimately reduce the size of the reactive sites the...	09/20/2011
7507851	Halocombstatins and methods of synthesis thereof The invention relates to novel compounds denominated halocombstatins. The halocombstatins are derivatives of combretastatin A-3, and include compounds that exhibit cancer growth cell inhibition against a panel of human cancer cell lines and the murine P388 leukemia,...	03/24/2009
7439289	Benzoylresorcinol-based phosphate ester compounds as flame retardants Benzoylresorcinol-based phosphate esters are obtained by reacting a benzoylresorcinol compound with a chlorophosphate. The benzoylresorcinol-based phosphate esters can function as flame retardants and/or UV stabilizers for polycarbonates (PC), poly(phenylene oxide) ...	10/21/2008
7365113	Phosphate ester flame retardants from resorcinol-ketone reaction products Flavan-based and spirodichroman compound-based phosphate esters prepared by reacting flavans and spirodichroman compounds with phosphorus oxychloride, monophenyl dichlorophosphate, or diphenyl chlorophosphate compounds are described. The flavans and spirodichroman c...	04/29/2008
7223747	Halocombstatins and methods of synthesis thereof The invention relates to novel compounds denominated halocombstatins. The halocombstatins are derivatives of combretastatin A-3, and include compounds that exhibit cancer growth cell inhibition against a panel of human cancer cell lines and the murine P388 leukemia,...	05/29/2007
7105501	Compositions with vascular damaging activity Compositions for the inhibition of the formation of new vaculature by angiogenesis are provided as in compounds which are salts comprising as an acidic component a compound of formula (1) wherein: R1, R2 and R3 are each independently...	09/12/2006
6855702	Combretastatin A-4 phosphate prodrug mono-and di-organic amine salts, mono-and di-amino acid salts, and mono-and di-amino acid ester salts Provided herein are novel and useful combretastatin A-4 prodrug salts that increase the solubility of combretastatin A-4, readily regenerate combretastatin A-4 in vivo under normal physiological conditions, and which produce physiologically tolerable products as a r...	02/15/2005
6743937	Efficient method of synthesizing combretastatin A-4 prodrugs Methods of synthesizing a phosphate ester of combretastatin A-4 and trans-isomers thereof in which combretastatin A-4 is reacted with dibenzylphosphite in the presence of carbon tetrabromide, or with 2,2,2-trichloroethyl phosphorodichloridate, to form a phosphate es...	06/01/2004
6670344	Combretastatin A-4 phosphate prodrug mono- and di-organic amine salts, mono- and di- amino acid salts, and mono- and di-amino acid ester salts Provided herein are novel and useful combretastatin A-4 prodrug salts that increase the solubility of combretastatin A-4, readily regenerate combretastatin A-4 in vivo under normal physiological conditions, and which produce physiologically tolerable prod...	12/30/2003
6486339	Phosphorylated product made by heating alkylated phenol in presence of solid acid catalyst The isomerization of an alkylated phenol composition that contains an ortho-alkyl substituted phenol component to isomerize and reduce the level of ortho-alkyl substituted phenol component therein can be accomplished by heating that composition in the pre...	11/26/2002
6299887	Phosphoric triesters and external compositions containing the same The present invention discloses phosphoric triesters represented by formula (1): ##STR1## wherein R1 represents C12-C24 alkyl or alkenyl, R2 represents C6-C24 alkyl, alkenyl, or aryl, and R3 represents C1-C6 alkyl, C2-C6 ...	10/09/2001
5936132	Alkene intermediates and synthesis thereof A chemiluminescent 1,2-dioxetane derivative having a formula (I): ##STR1## wherein R1 and R4 each represent, individually, hydrogen, an alkyl group, an alkoxyl group, a hydroxyl group, or --OS;(R9 R10 R	08/10/1999
5714361	Phosphatase/phosphodiesterase enzyme inhibitors and methods Described are preferred suicide inhibitors of phosphatase or phosphodiesterase enzymes, and methods for preparing halo enol phosphates which can serve as such suicide inhibitors....	02/03/1998
5561122	Combretastatin A-4 prodrug Disclosed herein are Combretastatin A-4 Prodrugs, having the general strure set forth below, which are useful in the treatment of one or more neoplastic diseases by means of chemotherapy. ##STR1##...	10/01/1996
5412140	Metal-free dithiophosphoric acid derivatives Alkyl glycidol ether/dithiophosphoric acid addition products corresponding to the following general formula: [R1 ]O[C(H)(H)][C(H)C(H)(H)(OH)(R4)] (I) in which R4 =[(R2 O)(R3 O)]P(S)S, R1 ...	05/02/1995
5245070	Alkyl phosphates having a branched alkyl group A compound represented by the following general formula I; ##STR1## wherein R1, R2 and R3 independently represent a hygrogen atom, alkyl group or aryl group, provided that at least one of R1, R2 ...	09/14/1993
5210261	Production of phosphorothioate salts Amine salts of phosphorothioic acids, useful for example in lubricant compositions, are made by forming a mixture of sulphur and an amine, and then adding a phosphite ester. The reaction is controlled by the rate of addition of the ester....	05/11/1993
5154754	Oil-in-water emulsions and a process for their preparation and their use Oil-in-water emulsions (microemulsions) containing 0.01-80% by weight of at least one agrochemical active substance of low water-solubility, one active substance for combating pests in the domestic and hygiene sector and/or one pharmacologically active su...	10/13/1992
5138084	Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives A process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives by treatment of a mixture of both 3-O-phosphate and 4-O-phosphate isomers with a strong mineral acid and optional esterification of the so obtained phosphoric ester of do...	08/11/1992
4814451	Process for preparing phosphorothioates and phosphates and phosphonothioates and phosphonates Certain phenyl and N-heterocyclic phosphorothioates and phosphonothioates and phosphates are prepared by the reaction of an appropriate alkali metal or alkaline earth metal --0-phenyl or N-heterocyclic compound with an appropriate phosphorochloridate, ph...	03/21/1989
4814448	Process for preparing phosphorothioates and phosphates Certain phenyl and N-heterocyclic phosphorothioates and phosphates are prepared by the reaction of an appropriate alkali metal or alkaline earth metal -O-phenyl or N-heterocyclic compound with an appropriate phosphorochloridate or phosphorochloridothioate...	03/21/1989
4803157	Hydrolyzable fluorescent substrates for phosphatases and analytical use thereof Hydrolyzable substrates for acid and alkaline phosphatases comprise blocked dye moieties which, when cleaved from the substrate during hydrolysis, provide fluorescent dyes having maximum absorptions above about 530 nm and maximum fluorescent emissions at ...	02/07/1989
4736053	Phosphoric ester derivatives and insecticidal and miticidal compositions containing said derivatives Disclosed are novel phosphoric ester derivatives of the formula (I): ##STR1## wherein R1 and R2 each represents a lower alkyl group; R3 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy g...	04/05/1988
4618447	Surfactant-based solvent system for dewatering different substrates This invention relates to improved drying compositions comprising a volatile halocarbon and one or more aromatic quaternary ammonium salts of a phosphate ester, and methods of using such compositions for cleaning and/or drying non-absorbent articles....	10/21/1986
4569930	2-Fluorophenyl(di)thiophosphates and their use in pest control 2-Fluorophenyl(di)thiophosphates of the formula ##STR1## where R1 is alkyl of 1 to 3 carbon atoms, R2 is alkyl or haloalkyl of 1 to 5 carbon atoms, alkoxyalkyl or alkylthioalkyl of 2 to 6 carbon atoms or cycloalkyl of 3 to 6 car...	02/11/1986
4511480	Corrosion inhibition in deep gas wells by phosphate esters of poly-oxyalkylated thiols Phosphate esters of oxyalkylated thiols are used as corrosion inhibitors for ferrous metals in deep gas wells....	04/16/1985
4496552	O-Halophenyl O-alkyl S-tert-butyl phosphorothioates as pesticides Compounds of the formula ##STR1## in which R1 is tertiary butyl, Ra and Rb are each bromine or chlorine, and Rc and Rd are each hydrogen, bromine or chlorine, having superior residual activity ag...	01/29/1985
4474776	Anthryl substituted phosphorus compounds as insecticides This invention discloses new insecticidal compounds of the formula ##STR1## wherein X and Y are each independently selected from the group consisting of halogen, alkyl, haloalkyl, nitro, alkylsulfinyl, alkylsulfonyl and cyano; m and n are integers fr...	10/02/1984
4462997	3-Fluorophenyl (di)thiophosphates, and their use for controlling pests 3-Fluorophenyl (di)thiophosphates of the formula ##STR1## where R1 is alkyl of 1 to 3 carbon atoms, R2 is alkyl or haloalkyl of 1 to 5 carbon atoms, alkoxyalkyl or alkylthioalkyl of 2 to 8 carbon atoms or cycloalkyl of 3 to 6 ca...	07/31/1984
4414208	O,S-Dialkyl-O-(4-fluorophenyl)-(di)thiophosphoric acid esters, and the use thereof for combating pests Novel O,S-dialkyl-O-(4-fluorophenyl)-(di)thiophosphoric acid esters of the formula ##STR1## where R1 is alkyl of from 1 to 3 carbon atoms, R2 is alkyl of from 1 to 5 carbon atoms, cycloalkyl of 5 or 6 carbon atoms, alkoxyalkyl ...	11/08/1983
4402883	Reclamation of organophosphate fluids Acidity of used organophosphate containing functional fluids is reduced by contact with activated alumina. The activated alumina is regenerated for reuse by a sequential leaching/heating process....	09/06/1983
4242333	Nematocidal unsubstituted phenyl esters of O-alkyl-S-alkyl-thiophosphoric acid New thiophosphoric acid esters of the formula ##STR1## and their manufacture are disclosed; in this formula R1 is methyl, yl, n-propyl or isopropyl and R2 is n-propyl or isopropyl. Such compounds are suitable as active ingredie...	12/30/1980
4171357	Cyclopropylmethylphosphoric acid derivatives New phosphoric acid derivatives, a process for their manufacture by reaction of cyclopropylmethyl halides with salts of phosphoric acid derivatives, and pesticides containing these new phosphoric acid derivatives as active ingredients....	10/16/1979
4152372	Thionophosphates Compounds which are useful as insecticide activators are described herein. The compounds are defined by the following formula: ##STR1## wherein R is selected from the group consisting of lower alkoxy, dimethyl, trimethyl, halogen, dihalogen, trifluor...	05/01/1979
4092312	Process for preparing phosphorothioates and phenylphosphonothioates Mixtures of (1) a quaternary ammonium salt(s) and (2) 1,4-diazabicyclo[2.2.2]octane are novel catalysts in the process of reacting an alkali metal phenate, pyridinate or pyrimidinate with an O,O-dialkyl phosphorochloridothioate or O-alkyl phenylphosp...	05/30/1978
4055638	Novel compounds, compositions containing such compounds, processes for their preparation and methods of treatment This invention relates to novel secondary phosphoric acid esters and salts thereof, having valuable pharmacological properties, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds,...	10/25/1977
4035488	Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters Organic phosphoric acid derivatives of the formula ##STR1## wherein R1 is C3 - C5 alkyl, optionally interrupted by oxygen or sulphur, R2 is methyl or ethyl, R3 is alkylcarbonyl, alkoxycarbonyl, aminoc...	07/12/1977
4028438	Phosphorothiolates Phosphorothiolates represented by the formula, ##STR1## wherein R is an alkyl; A is an alkyl, haloalkyl, alkenyl, alkinyl, alkylthioalkyl, phenylthioalkyl, phthalimidoalkyl or phenylalkyl; X is hydrogen, a halogen or an alkyl; and n is an integer of ...	06/07/1977
4025583	Amine adducts of ethyl oleyl acid orthophosphate Disclosed are lubricant compositions containing adducts of an amine with a phosphate ester of the formula: ##STR1## wherein R is hydrogen or alkyl having up to 25 carbon atoms in the chain, R' is hydrogen or alkyl having up to 7 carbon atoms except o...	05/24/1977
4006204	Phosphoric acid diesters The invention relates to compounds represented by the following general structure: ##STR1## and their method of making. These compounds are therapeutically useful as anti-inflammatory agents and operate as inhibitors of prostaglandin synthetase ...	02/01/1977

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Class 558/210 - Benzene ring bonded directly to one of the chalcogens