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| Number | Title | Issue Date |
| 7399877 | Phospholipid derivative A phospholipid derivative represented by the following formula (I) wherein R1CO and R2CO independently represent an acyl group; R3 represents hydrogen atom, or a hydrocarbon group; symbol “a” represents an integer of 0 to 4; symb... | 07/15/2008 |
| 7141557 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.... | 11/28/2006 |
| 7135584 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.... | 11/14/2006 |
| 6150344 | Hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases Compounds of Formula I ##STR1## are disclosed as inhibitors having activity against the aspartyl proteases, plasmepsin and cathepsin D. The compounds are therefore useful for treatment of diseases such as malaria and Alzheimer's disease. In pref... | 11/21/2000 |
| 6136797 | Phospholipid derivatives of phosphono-carboxylic acids, the production of said derivatives and the use of said derivatives as antiviral medicaments The present invention concerns new lipid derivatives of phosphonocarboxylic acids of the general formula I, ##STR1## in which the meaning of the symbols is elucidated in the description, tautomers thereof and their physiologically tolerated esters an... | 10/24/2000 |
| 6030960 | Method of treating hepatitis virus infections A method of treating hepatitis virus infection is disclosed. The method comprising administering to a human subject in need of such treatment an effective hepatitis virus-combatting amount of an alkyl lipid or alkyl lipid derivative.... | 02/29/2000 |
| 5916922 | Phenyl glyoxamides as SPLA2 inhibitors A class of novel phenyl glyoxamides is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.... | 06/29/1999 |
| 5770584 | Method of treating hepatitis virus infections A method of treating hepatitis virus infection is disclosed. The method comprising administering to a human subject in need of such treatment an effective hepatitis virus-combatting amount of an alkyl lipid or alkyl lipid derivative.... | 06/23/1998 |
| 5741923 | Ethylenically unsaturated compounds An improved process for producing ethylenically unsaturated phosphate ester compounds, especially 2-(methacryloyloxyethyl)-2' (trimethylammoniomethyl) phosphate, (HEMA-PC) comprises a two step reaction in the first of which a phospholane reagent is reacte... | 04/21/1998 |
| 5686633 | Inks, particularly for ink jet printing Inks, particularly inks for ink jet printing, contain at least one compound of the formula I ##STR1## as a stabilizer. The symbols R1, R2, R3, R4, R3 ' and R4 ' are as defined in claim... | 11/11/1997 |
| 5639732 | Phosphorous-containing cysteine and serine protease inhibitors The present invention is directed to novel phosphorous-containing inhibitors of cysteine or serine proteases. Methods for the use of the protease inhibitors are also described.... | 06/17/1997 |
| 5519006 | Phosphonated arylethanolamine compounds with anti-hyperglycemic and/or anti-obesity activity | 05/21/1996 |
| 5505936 | Phosphoric diesters which absorb UV rays, method of preparing the same, and cosmetic compositions containing the same Phosphoric diesters having formula (1): ##STR1## wherein R1 is an acyl group having at least one phenyl group; R2 is a C2-12 linear or branched alkylene group which may optionally be inserted with an oxygen atom betwe... | 04/09/1996 |
| 5436245 | Phosphate substituted amino or imino acids useful as antihypertensives Hypotensive activity is exhibited by new phosphonate substituted amino or imino acids of the formula ##STR1## isomeric mixtures thereof and pharmaceutically acceptable salts thereof, wherein: X is an imino or amino acid of the formula ##STR2##... | 07/25/1995 |
| 5344930 | Fluorine and phosphorous-containing amphiphilic molecules with surfactant properties Compounds of the general formula: ##STR1## are useful as surfactants in the preparation of fluorocarbon emulsions, which can be used as oxygen-carrying blood substitutes, and for many other therapeutic and diagnostic applications. They are further us... | 09/06/1994 |
| 5329029 | Phosphatidylalkanolamine derivatives and their use in generating phospholipid conjugates An efficient, technically straightforward and inexpensive process for generating conjugates of phospholipids with biologically important molecules is described.... | 07/12/1994 |
| 5151521 | 1-aminoethyl phosphonic acid derivatives New phosphonic acid derivatives are described which display antibacterial activity.... | 09/29/1992 |
| 5073547 | Dopamine pro-drug A monophosphorylated L-dopa ester of formula ##STR1## (wherein the asterisk, R, R1, R2 and R3 have the meanings shown in the description), salts thereof with pharmaceutically acceptable acids or bases, a process for t... | 12/17/1991 |
| 5061806 | Phosphinic acid derivatives New phosphonic acid derivatives are described which display antibacterial activity.... | 10/29/1991 |
| 5051413 | Unsaturated amino acids The invention relates to unsaturated amino acids of the formula I ##STR1## in which R1 represents hydroxy or etherified hydroxy, R2 represents hydrogen, alkyl, hydroxy or etherified hydroxy, R3 represents hydrogen, al... | 09/24/1991 |
| 5006651 | Phosphinic acid derivatives The invention relates compounds of the formula ##STR1## wherein R1 -R5 and X have the significance given in the description, and their pharmaceutically acceptable salts. The compounds of formula I inhibit the enzyme collagenase ... | 04/09/1991 |
| 4906764 | Process for producing phosphinylamino acid derivatives A process for producing a phosphinylamino acid derivative of the formula: ##STR1## wherein R1 is a lower alkyl group, R2 is a hydrogen atom, a lower alkyl group, a halo-lower alkyl group or a substituted or unsubstituted phenyl ... | 03/06/1990 |
| 4897166 | Antifoaming additive for acid liquids Acidic liquids, such as galvanic electrolyte solutions for metal electroplating, contain a surfactant and a foam inhibiting agent which is a perfluoroalkyl-containing ester of phosphoric acid.... | 01/30/1990 |
| 4886542 | Herbicide compositions of N-(phosphonomethylglycyl) sulfonylamines and process for using same Herbicidal compounds of formula: ##STR1## in which R1 denotes an optionally halogenated alkyl radical containing from 1 to 4 carbon atoms, R denotes the hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, R2 den... | 12/12/1989 |
| 4788182 | Phosphatidyl compounds, processes for their manufacture, and their use Described are phosphatidyl compounds of the formula I ##STR1## in which R1 represents C3-14 -alkanoyl, benzoyl, the acyl radical of an -aminocarboxylic acid that is other than glycine, L-alanine and derivatives thereof ha... | 11/29/1988 |
| 4777279 | Process for the preparation of L-homoalanin-4-yl(methyl)-phosphinic acid and its alkyl esters Process for the preparation of L-homoalanin-4-yl(methyl)-phosphinic acid (esters) of the formula I ##STR1## (R, R1 =H, alkyl) or salts thereof by reacting an R-3-isopropyl-2,5-dialkoxy-3,6-dihydropyrazine of the formula II with a �... | 10/11/1988 |
| 4755614 | Preparation of herbicides containing a phosphonate group from intermediate benzoxazines Preparation of intermediates for herbicides of formula ##STR1## by the reaction of organic phosphites with benzoxazines of formula in which Bzx denotes the radical of formula: ##STR2## X is a usual substituent of phenols n is an integer from 0 to 4 R... | 07/05/1988 |
| 4755209 | Certain herbicidal 2-pyridyloxy(or phenoxy)-phenoxy-lower alkanoylaminomethylene-phosphonil acids or esters thereof A phenoxyalkanoylaminomethylphosphonic acid represented by the following formula (I) ##STR1## wherein X and Y are identical or different and each represents a hydrogen atom, a halogen atom, CF3 or an alkyl group having not more than 5 ... | 07/05/1988 |
| 4738708 | N-sulphonyl-N-[N'phosphonomethylglycyl]amine and derivatives as herbicides Herbidical compounds of the formula: ##STR1## in which R1 denotes an optionally substituted hydrocarbon radical, R denotes the hydrogen atom or has one of the meanings given for R1 ; R2 and R3 denote the hy... | 04/19/1988 |
| 4723029 | Organic acid-substituted guanidine anthelmintics This invention relates to organic acid-substituted guanidine compounds. Also disclosed are methods for preparing the compounds, compositions containing them, and methods for their use as anthelmintics.... | 02/02/1988 |
| 4716156 | Phosphonodithioylacetyl phenyl aminoacid ethyl esters Novel compounds having the formula ##STR1## wherein R is lower alkyl having 1 to 6 carbon atoms, have shown utility as insecticides and miticides.... | 12/29/1987 |
| 4654072 | Herbicidal phosphonomethyl amides Compounds having the formula ##STR1## in which R is hydrogen, cyano or --COOR2 ; R1 is hydrogen or C1 -C4 alkyl; R2 is hydrogen or C1 -C4 alkyl; and Z is ##STR2## ... | 03/31/1987 |
| 4599205 | 1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids The invention is related to 1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids having the formula I ##STR1##... | 07/08/1986 |
| 4579691 | Haloacylaminoalkylphosphonates When applied as safeners, the haloacylaminoalkylphosphinates, haloacylaminoalkylphosphinates and haloacylaminoalkylphosphine oxides of the formula I below are able to protect cultivated plants from the phytotoxic effects of herbicides. Suitable crops are ... | 04/01/1986 |
| 4560752 | Phosphinates or phosphonates useful for control of weeds Novel 5-(substituted amino)phenoxyalkyl-, phenylthioalkyl-, phenylsulfinylalkyl-, and phenylsulfonylalkylphosphinates and phosphonates, synthesis thereof, intermediates therefor, and the use of said novel compounds for the control of weeds.... | 12/24/1985 |
| 4534899 | Synthetic phospholipid compounds Synthetic phospholipid compounds and their method of preparation, which compounds are phosphatidylethanolamine polycarboxyl polyalkylene glycols and are prepared by the reaction of a phosphatidylethanolamine, a polycarboxylic acid, such as succinic or glu... | 08/13/1985 |
| 4483853 | Amino acid isomers, their production and their medicinal use The (-)-D-isomers of compounds of the general formula ##STR1## in which X stands for an acidic radical, especially a radical of phosphonic acid, sulphonic acid, boronic acid or tetrazole, R stands for an alkylene, alkenylene or alkynylene radical with 3 o... | 11/20/1984 |
| 4454073 | N-[Carboxyl(carbamoyl)carbonyl)-aminomethyl phosphonic acids Substituted methylphosphonic acids as herbicides.... | 06/12/1984 |
| 4426525 | Certain phosphoric acid ester derivatives of 1,3-dioxy propane Tridecyloxy- or tetradecyloxy-propane derivatives of the formula: ##STR1## wherein R1 is tridecyl or tetradecyl, R2 is hydrogen or --OCH3, and R3, R4 and R5 independently represent hyd... | 01/17/1984 |
| 4416831 | Amino and substituted amino phosphinylalkanoyl compounds Compounds of the formula ##STR1## wherein X is an imino acid or ester and R1 is hydrogen, ##STR2## are useful hypotensive agents due to their angiotensin converting enzyme inhibition activity.... | 11/22/1983 |
